Snx18 (sorting nexin 18) - Rat Genome Database

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Gene: Snx18 (sorting nexin 18) Ictidomys tridecemlineatus
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Symbol: Snx18
Name: sorting nexin 18
RGD ID: 12564267
Description: ENCODES a protein that exhibits phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN mitotic cytokinesis (ortholog); positive regulation of autophagosome assembly (ortholog); positive regulation of GTPase activity (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN clathrin-coated vesicle (ortholog); cytoplasmic side of plasma membrane (ortholog); extracellular exosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sorting nexin-18
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213204,025,143 - 204,201,070 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648013,108,510 - 13,137,550 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Snx18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213204,025,143 - 204,201,070 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648013,108,510 - 13,137,550 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNX18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38554,517,759 - 54,648,005 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl554,517,759 - 54,546,586 (+)EnsemblGRCh38hg38GRCh38
GRCh37553,813,589 - 53,842,416 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36553,849,350 - 53,878,173 (+)NCBINCBI36Build 36hg18NCBI36
Build 34553,849,539 - 53,851,426NCBI
Celera550,767,064 - 50,795,890 (+)NCBICelera
Cytogenetic Map5q11.2NCBI
HuRef550,787,437 - 50,816,259 (+)NCBIHuRef
CHM1_1553,816,580 - 53,845,409 (+)NCBICHM1_1
T2T-CHM13v2.0555,345,475 - 55,475,784 (+)NCBIT2T-CHM13v2.0
Snx18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913113,728,715 - 113,755,100 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13113,728,715 - 113,755,100 (-)EnsemblGRCm39 Ensembl
GRCm3813113,592,179 - 113,618,564 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13113,592,179 - 113,618,564 (-)EnsemblGRCm38mm10GRCm38
MGSCv3713114,382,387 - 114,408,772 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613114,713,061 - 114,739,419 (-)NCBIMGSCv36mm8
Celera13117,901,784 - 117,928,168 (-)NCBICelera
Cytogenetic Map13D2.2NCBI
cM Map1364.0NCBI
Snx18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8246,965,498 - 46,991,516 (-)NCBIGRCr8
mRatBN7.2245,232,325 - 45,258,345 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl245,232,325 - 45,258,345 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx252,343,993 - 52,369,979 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0250,402,361 - 50,428,348 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0245,274,943 - 45,301,291 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0245,454,782 - 45,480,798 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl245,454,782 - 45,480,798 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0264,486,855 - 64,512,619 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4245,014,383 - 45,040,586 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1244,943,876 - 45,006,230 (-)NCBI
Celera241,000,711 - 41,026,746 (-)NCBICelera
Cytogenetic Map2q14NCBI
Snx18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544613,043,821 - 13,067,933 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544613,043,821 - 13,067,933 (-)NCBIChiLan1.0ChiLan1.0
SNX18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2459,181,347 - 59,419,695 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1557,334,972 - 57,573,292 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0559,270,053 - 59,508,359 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1561,101,061 - 61,129,397 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl561,101,056 - 61,129,397 (-)Ensemblpanpan1.1panPan2
SNX18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1460,803,245 - 60,945,317 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl460,835,783 - 60,945,828 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha460,569,927 - 60,710,959 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0461,295,275 - 61,436,640 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl461,302,014 - 61,436,904 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1461,185,900 - 61,215,498 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0461,201,579 - 61,342,650 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0461,720,198 - 61,861,418 (-)NCBIUU_Cfam_GSD_1.0
SNX18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1633,776,746 - 33,847,624 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11633,776,964 - 33,801,391 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21635,846,933 - 35,859,015 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SNX18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1450,782,842 - 50,810,220 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl450,782,929 - 50,811,253 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666082261,616 - 288,960 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Snx18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247594,850,555 - 4,879,478 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247594,851,014 - 4,879,365 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_005319637   ⟹   XP_005319694
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213204,172,015 - 204,201,070 (-)NCBI
SpeTri2.0NW_00493648013,108,510 - 13,137,550 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040271843   ⟹   XP_040127777
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213204,034,125 - 204,201,070 (-)NCBI
RefSeq Acc Id: XM_040271844   ⟹   XP_040127778
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213204,025,143 - 204,201,070 (-)NCBI
RefSeq Acc Id: XR_005727736
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213204,037,976 - 204,201,070 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005319694 (Get FASTA)   NCBI Sequence Viewer  
  XP_040127777 (Get FASTA)   NCBI Sequence Viewer  
  XP_040127778 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000019958.2
GenBank Protein KAG3266691 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005319694   ⟸   XM_005319637
- Peptide Label: isoform X1
- UniProtKB: I3N6G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040127778   ⟸   XM_040271844
- Peptide Label: isoform X3
- UniProtKB: I3N6G2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040127777   ⟸   XM_040271843
- Peptide Label: isoform X2
- UniProtKB: I3N6G2 (UniProtKB/TrEMBL)
Protein Domains
PX   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000025844 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000024003.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.60 UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/TrEMBL
  PX_dom UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  SNX18_PX UniProtKB/TrEMBL
  SNX18_SH3 UniProtKB/TrEMBL
  Snx9_fam UniProtKB/TrEMBL
  Sorting_nexin_WASP-bd-dom UniProtKB/TrEMBL
NCBI Gene Snx18 ENTREZGENE
PANTHER PTHR45827:SF4 UniProtKB/TrEMBL
  SORTING NEXIN UniProtKB/TrEMBL
Pfam BAR_3_WASP_bdg UniProtKB/TrEMBL
  PF00787 UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PIRSF Snx9 UniProtKB/TrEMBL
PROSITE PS50195 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART SH3 UniProtKB/TrEMBL
  SM00312 UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/TrEMBL
  SSF64268 UniProtKB/TrEMBL
UniProt I3N6G2 ENTREZGENE, UniProtKB/TrEMBL