Tpm4 (tropomyosin 4) - Rat Genome Database

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Gene: Tpm4 (tropomyosin 4) Ictidomys tridecemlineatus
Analyze
Symbol: Tpm4
Name: tropomyosin 4
RGD ID: 12563049
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN platelet formation (inferred); ASSOCIATED WITH Acute Coronary Syndrome (ortholog); asbestosis (ortholog); Esophageal Neoplasms (ortholog); FOUND IN actin cytoskeleton (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tropomyosin alpha-4 chain
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118204,857,159 - 204,874,401 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365964,406,283 - 4,418,932 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365964,406,301 - 4,423,775 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Tpm4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118204,857,159 - 204,874,401 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365964,406,283 - 4,418,932 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365964,406,301 - 4,423,775 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TPM4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381916,067,538 - 16,103,002 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1916,067,021 - 16,103,005 (+)EnsemblGRCh38hg38GRCh38
GRCh371916,178,348 - 16,213,812 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361916,048,325 - 16,074,408 (+)NCBINCBI36Build 36hg18NCBI36
Build 341916,048,324 - 16,074,408NCBI
Celera1916,080,322 - 16,115,740 (+)NCBICelera
Cytogenetic Map19p13.12-p13.11NCBI
HuRef1915,749,181 - 15,784,766 (+)NCBIHuRef
CHM1_11916,177,722 - 16,213,291 (+)NCBICHM1_1
T2T-CHM13v2.01916,201,542 - 16,237,074 (+)NCBIT2T-CHM13v2.0
Tpm4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39872,889,132 - 72,906,986 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl872,884,018 - 72,906,986 (+)EnsemblGRCm39 Ensembl
GRCm38872,135,288 - 72,153,142 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl872,130,174 - 72,153,142 (+)EnsemblGRCm38mm10GRCm38
MGSCv37874,659,191 - 74,677,028 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36875,064,281 - 75,082,118 (+)NCBIMGSCv36mm8
Celera876,490,967 - 76,508,585 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.81NCBI
Tpm4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81617,718,442 - 17,732,483 (-)NCBIGRCr8
mRatBN7.21617,684,415 - 17,698,456 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1617,683,195 - 17,705,984 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1617,743,321 - 17,757,333 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01618,875,963 - 18,889,968 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01617,796,254 - 17,810,266 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01619,385,810 - 19,399,851 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1619,385,736 - 19,399,903 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01619,244,141 - 19,258,182 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41618,108,914 - 18,122,956 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11618,108,911 - 18,122,954 (-)NCBI
Celera1617,899,051 - 17,913,092 (-)NCBICelera
Cytogenetic Map16p14NCBI
Tpm4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555241,415,848 - 1,432,139 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555241,419,061 - 1,432,114 (-)NCBIChiLan1.0ChiLan1.0
TPM4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22020,938,579 - 20,975,280 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11919,945,282 - 19,981,066 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01915,557,683 - 15,593,143 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11916,540,805 - 16,575,675 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1916,540,805 - 16,575,312 (+)Ensemblpanpan1.1panPan2
TPM4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12046,354,808 - 46,376,489 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2046,355,736 - 46,376,425 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2046,269,322 - 46,291,014 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02046,844,446 - 46,864,961 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2046,821,781 - 46,864,926 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12046,077,842 - 46,099,527 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02046,489,401 - 46,511,083 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02046,765,733 - 46,787,433 (-)NCBIUU_Cfam_GSD_1.0
TPM4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl261,453,725 - 61,476,781 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1261,453,721 - 61,476,781 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2261,150,543 - 61,173,575 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap2q24-q29NCBI
TPM4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1614,566,958 - 14,604,754 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl614,566,869 - 14,598,934 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660744,891,204 - 4,926,682 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tpm4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,132,215 - 1,152,319 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249081,135,240 - 1,155,175 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000019734   ⟹   ENSSTOP00000019886
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365964,406,283 - 4,418,932 (-)Ensembl
RefSeq Acc Id: XM_021731524   ⟹   XP_021587199
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118204,857,159 - 204,874,401 (-)NCBI
SpeTri2.0NW_0049365964,406,301 - 4,423,540 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021731525   ⟹   XP_021587200
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118204,861,872 - 204,874,401 (-)NCBI
SpeTri2.0NW_0049365964,411,011 - 4,423,775 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_021587199 (Get FASTA)   NCBI Sequence Viewer  
  XP_021587200 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000019886.2
RefSeq Acc Id: XP_021587199   ⟸   XM_021731524
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021587200   ⟸   XM_021731525
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSSTOP00000019886   ⟸   ENSSTOT00000019734


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000024252 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000019734.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  1.20.5.370 UniProtKB/TrEMBL
InterPro Tropomyosin UniProtKB/TrEMBL
  XRCC4-like_C UniProtKB/TrEMBL
NCBI Gene Tpm4 ENTREZGENE
PANTHER TROPOMYOSIN UniProtKB/TrEMBL
  TROPOMYOSIN 4-RELATED UniProtKB/TrEMBL
Pfam Tropomyosin UniProtKB/TrEMBL
PRINTS TROPOMYOSIN UniProtKB/TrEMBL
PROSITE TROPOMYOSIN UniProtKB/TrEMBL
Superfamily-SCOP Tropomyosin UniProtKB/TrEMBL
UniProt I3N690_ICTTR UniProtKB/TrEMBL