Trpa1 (transient receptor potential cation channel subfamily A member 1) - Rat Genome Database

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Gene: Trpa1 (transient receptor potential cation channel subfamily A member 1) Ictidomys tridecemlineatus
Analyze
Symbol: Trpa1
Name: transient receptor potential cation channel subfamily A member 1
RGD ID: 12561715
Description: ENCODES a protein that exhibits osmolarity-sensing monoatomic cation channel activity (ortholog); voltage-gated calcium channel activity (ortholog); INVOLVED IN calcium ion transmembrane import into cytosol (ortholog); calcium ion transport (ortholog); cellular response to caffeine (ortholog); ASSOCIATED WITH Abdominal Pain (ortholog); asthma (ortholog); Bronchial Hyperreactivity (ortholog); FOUND IN apical plasma membrane (ortholog); axon (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530358,307,190 - 58,354,763 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366481,094,460 - 1,141,394 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366481,094,460 - 1,141,394 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Trpa1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530358,307,190 - 58,354,763 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366481,094,460 - 1,141,394 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366481,094,460 - 1,141,394 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRPA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38872,021,250 - 72,090,010 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl872,019,917 - 72,075,584 (-)EnsemblGRCh38hg38GRCh38
GRCh37872,933,485 - 72,987,819 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36873,096,040 - 73,150,373 (-)NCBINCBI36Build 36hg18NCBI36
Build 34873,096,039 - 73,150,373NCBI
Celera868,932,963 - 68,987,289 (-)NCBICelera
Cytogenetic Map8q21.11NCBI
HuRef868,428,222 - 68,482,529 (-)NCBIHuRef
CHM1_1872,986,840 - 73,041,189 (-)NCBICHM1_1
T2T-CHM13v2.0872,456,370 - 72,525,074 (-)NCBIT2T-CHM13v2.0
Trpa1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39114,942,868 - 14,989,086 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl114,942,872 - 14,989,086 (-)EnsemblGRCm39 Ensembl
GRCm38114,872,644 - 14,918,862 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl114,872,648 - 14,918,862 (-)EnsemblGRCm38mm10GRCm38
MGSCv37114,862,729 - 14,908,943 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36114,857,862 - 14,904,076 (-)NCBIMGSCv36mm8
Celera114,822,489 - 14,871,741 (-)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.5NCBI
Trpa1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr859,163,060 - 9,217,325 (+)NCBIGRCr8
mRatBN7.254,379,862 - 4,434,133 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl54,379,999 - 4,433,570 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx56,513,645 - 6,566,735 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.058,152,548 - 8,205,642 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.057,846,752 - 7,899,532 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.053,783,247 - 3,836,485 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl53,783,247 - 3,836,485 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.053,764,339 - 3,818,781 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.453,531,163 - 3,584,401 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.153,531,162 - 3,584,401 (+)NCBI
Celera53,971,809 - 4,024,939 (+)NCBICelera
Cytogenetic Map5q11NCBI
Trpa1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554447,876,429 - 7,921,372 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554447,876,284 - 7,922,010 (+)NCBIChiLan1.0ChiLan1.0
TRPA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2787,759,979 - 87,813,795 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1863,389,306 - 63,443,548 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0868,551,685 - 68,605,336 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1870,208,697 - 70,262,802 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl870,210,352 - 70,262,627 (-)Ensemblpanpan1.1panPan2
TRPA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12920,951,736 - 21,000,956 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2920,951,716 - 21,001,208 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2921,214,374 - 21,266,355 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02921,050,161 - 21,102,458 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2921,050,159 - 21,111,731 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12921,102,449 - 21,154,677 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02921,151,285 - 21,203,541 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02921,431,610 - 21,483,919 (-)NCBIUU_Cfam_GSD_1.0
TRPA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl463,508,104 - 63,558,484 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1463,493,374 - 63,558,486 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2469,132,584 - 69,265,553 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRPA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1867,698,067 - 67,754,407 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl867,698,786 - 67,751,885 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603973,636,128 - 73,694,618 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trpa1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474418,997,462 - 19,042,227 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474418,997,273 - 19,042,838 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000005048   ⟹   ENSSTOP00000004528
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366481,094,460 - 1,141,394 (-)Ensembl
Ensembl Acc Id: ENSSTOT00000039754   ⟹   ENSSTOP00000024236
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366481,094,460 - 1,141,394 (-)Ensembl
RefSeq Acc Id: XM_040293955   ⟹   XP_040149889
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530358,307,190 - 58,354,763 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040149889 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AUF73697 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000004528.3
  ENSSTOP00000024236.1
RefSeq Acc Id: XP_040149889   ⟸   XM_040293955
- UniProtKB: A0A2H4ZCP8 (UniProtKB/TrEMBL),   I3M5D3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000024236   ⟸   ENSSTOT00000039754
Ensembl Acc Id: ENSSTOP00000004528   ⟸   ENSSTOT00000005048
Protein Domains
Ion transport


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000005024 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000005048.3 UniProtKB/TrEMBL
  ENSSTOT00000039754.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/TrEMBL
  TRP_cation_channel UniProtKB/TrEMBL
NCBI Gene Trpa1 ENTREZGENE
PANTHER TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS UniProtKB/TrEMBL
  TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS UniProtKB/TrEMBL
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
  Ank_3 UniProtKB/TrEMBL
  Ion_trans UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt A0A287CSH2_ICTTR UniProtKB/TrEMBL
  A0A2H4ZCP8 ENTREZGENE, UniProtKB/TrEMBL
  I3M5D3 ENTREZGENE, UniProtKB/TrEMBL