Kcnb2 (potassium voltage-gated channel subfamily B member 2) - Rat Genome Database

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Gene: Kcnb2 (potassium voltage-gated channel subfamily B member 2) Ictidomys tridecemlineatus
Analyze
Symbol: Kcnb2
Name: potassium voltage-gated channel subfamily B member 2
RGD ID: 12537192
Description: ENCODES a protein that exhibits protein heterodimerization activity (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN protein localization to plasma membrane (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); colorectal cancer (ortholog); FOUND IN neuronal cell body (ortholog); neuronal cell body membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium voltage-gated channel, Shab-related subfamily, member 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530357,711,390 - 58,087,221 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366481,361,422 - 1,734,672 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcnb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530357,711,390 - 58,087,221 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366481,361,422 - 1,734,672 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38872,537,225 - 72,938,349 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl872,537,225 - 72,938,349 (+)EnsemblGRCh38hg38GRCh38
GRCh37873,449,460 - 73,850,584 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36873,612,180 - 74,013,138 (+)NCBINCBI36Build 36hg18NCBI36
Build 34873,612,179 - 74,013,136NCBI
Celera869,452,496 - 69,847,725 (+)NCBICelera
Cytogenetic Map8q21.11NCBI
HuRef868,946,299 - 69,341,459 (+)NCBIHuRef
CHM1_1873,502,691 - 73,903,408 (+)NCBICHM1_1
T2T-CHM13v2.0872,972,288 - 73,367,350 (+)NCBIT2T-CHM13v2.0
Kcnb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,357,149 - 15,793,975 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,357,478 - 15,793,974 (+)EnsemblGRCm39 Ensembl
GRCm38115,286,925 - 15,723,751 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,287,254 - 15,723,750 (+)EnsemblGRCm38mm10GRCm38
MGSCv37115,302,533 - 15,704,295 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,297,666 - 15,696,895 (+)NCBIMGSCv36mm8
MGSCv36115,858,607 - 15,860,301 (+)NCBIMGSCv36mm8
Celera115,251,474 - 15,665,920 (+)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.5NCBI
Kcnb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr858,340,085 - 8,811,184 (-)NCBIGRCr8
mRatBN7.253,567,012 - 4,028,564 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl53,569,685 - 4,028,599 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx55,686,237 - 6,146,556 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.057,325,121 - 7,785,453 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.057,023,712 - 7,485,422 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.052,975,934 - 3,430,837 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.052,965,248 - 3,418,192 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.452,683,952 - 3,154,913 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.152,683,951 - 3,154,908 (-)NCBI
Celera53,165,386 - 3,621,344 (-)NCBICelera
Cytogenetic Map5q11NCBI
Kcnb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554447,237,011 - 7,646,399 (-)NCBIChiLan1.0ChiLan1.0
KCNB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2788,278,471 - 88,685,017 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1863,904,517 - 64,314,700 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0869,069,427 - 69,481,855 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1870,756,092 - 71,123,156 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl870,756,185 - 71,122,897 (+)Ensemblpanpan1.1panPan2
KCNB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12921,248,531 - 21,604,564 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2921,248,531 - 21,604,871 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2921,505,987 - 21,882,104 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02921,342,535 - 21,725,967 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2921,349,860 - 21,713,876 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12921,402,617 - 21,785,087 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02921,443,369 - 21,808,927 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02921,725,677 - 22,102,596 (+)NCBIUU_Cfam_GSD_1.0
KCNB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl462,879,266 - 63,307,794 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1462,877,838 - 63,306,314 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KCNB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1868,165,879 - 68,538,285 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603972,849,081 - 73,253,865 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474418,240,912 - 18,659,530 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474418,240,321 - 18,687,157 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_005335823   ⟹   XP_005335880
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530357,711,390 - 58,086,522 (-)NCBI
SpeTri2.0NW_0049366481,362,062 - 1,734,672 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021733630   ⟹   XP_021589305
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530357,711,392 - 58,087,221 (-)NCBI
SpeTri2.0NW_0049366481,361,422 - 1,734,672 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040293954   ⟹   XP_040149888
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530357,711,390 - 57,720,122 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005335880 (Get FASTA)   NCBI Sequence Viewer  
  XP_021589305 (Get FASTA)   NCBI Sequence Viewer  
  XP_040149888 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000029375.1
RefSeq Acc Id: XP_005335880   ⟸   XM_005335823
- Peptide Label: isoform X1
- UniProtKB: A0A287D755 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021589305   ⟸   XM_021733630
- Peptide Label: isoform X1
- UniProtKB: A0A287D755 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040149888   ⟸   XM_040293954
- Peptide Label: isoform X2
- UniProtKB: A0A287D755 (UniProtKB/TrEMBL)
Protein Domains
Ion transport


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000032334 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000041966.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  Voltage-gated potassium channels. Chain C UniProtKB/TrEMBL
InterPro Ion_trans_dom UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv2 UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv2.2 UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/TrEMBL
NCBI Gene Kcnb2 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY B MEMBER 2 UniProtKB/TrEMBL
  VOLTAGE-GATED POTASSIUM CHANNEL UniProtKB/TrEMBL
Pfam Ion_trans UniProtKB/TrEMBL
  Kv2channel UniProtKB/TrEMBL
PRINTS KCHANNEL UniProtKB/TrEMBL
  KV22CHANNEL UniProtKB/TrEMBL
  KVCHANNEL UniProtKB/TrEMBL
  SHABCHANNEL UniProtKB/TrEMBL
Superfamily-SCOP Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A287D755 ENTREZGENE, UniProtKB/TrEMBL