Zkscan1 (zinc finger with KRAB and SCAN domains 1) - Rat Genome Database

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Gene: Zkscan1 (zinc finger with KRAB and SCAN domains 1) Ictidomys tridecemlineatus
Analyze
Symbol: Zkscan1 (Ensembl: ZSCAN21)
Name: zinc finger with KRAB and SCAN domains 1 (Ensembl:zinc finger and SCAN domain containing 21)
RGD ID: 12515002
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN male meiosis I (inferred); positive regulation of DNA-templated transcription (inferred); positive regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH intellectual disability (ortholog); pleomorphic xanthoastrocytoma (ortholog); prostate cancer (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC101968831; zinc finger and SCAN domain containing 21; zinc finger and SCAN domain-containing protein 21; zinc finger protein with KRAB and SCAN domains 1; zinc finger with KRAB and SCAN domains 1, transcript variant X1; zinc finger with KRAB and SCAN domains 1, transcript variant X2; zinc finger with KRAB and SCAN domains 1, transcript variant X3; zinc finger with KRAB and SCAN domains 1, transcript variant X4; Zscan21
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,844,331 - 133,885,668 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543180,662 - 192,238 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_004936543150,850 - 165,282 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936543150,845 - 192,197 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Zkscan1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,844,331 - 133,885,668 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543180,662 - 192,238 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_004936543150,850 - 165,282 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936543150,845 - 192,197 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZKSCAN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,015,596 - 100,045,374 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,015,572 - 100,041,689 (+)EnsemblGRCh38hg38GRCh38
GRCh37799,613,219 - 99,642,997 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36799,451,155 - 99,473,339 (+)NCBINCBI36Build 36hg18NCBI36
Build 34799,257,869 - 99,280,054NCBI
Celera794,347,766 - 94,369,948 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,248,895 - 94,270,995 (+)NCBIHuRef
CHM1_1799,543,395 - 99,565,575 (+)NCBICHM1_1
T2T-CHM13v2.07101,255,101 - 101,284,872 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2798,973,342 - 98,995,525 (+)NCBI
Zkscan1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395138,083,312 - 138,106,084 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5138,083,346 - 138,106,084 (+)EnsemblGRCm39 Ensembl
GRCm385138,085,050 - 138,107,822 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5138,085,084 - 138,107,822 (+)EnsemblGRCm38mm10GRCm38
MGSCv375138,526,312 - 138,549,050 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365138,314,872 - 138,337,610 (+)NCBIMGSCv36mm8
Celera5135,064,847 - 135,087,824 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.95NCBI
Zkscan1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81222,080,319 - 22,101,389 (+)NCBIGRCr8
mRatBN7.21216,966,287 - 16,987,680 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1216,966,654 - 16,983,865 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1217,789,870 - 17,806,147 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,413,615 - 18,429,892 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01217,467,019 - 17,483,296 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01219,231,092 - 19,247,393 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,231,092 - 19,247,387 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,289,534 - 21,310,622 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41217,530,383 - 17,546,785 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1218,897,020 - 18,913,306 (+)NCBICelera
Cytogenetic Map12q11NCBI
Zkscan1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955573830,342 - 836,216 (-)EnsemblChiLan1.0
ChiLan1.0 EnsemblNW_004955573854,380 - 869,870 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955573830,897 - 869,857 (-)NCBIChiLan1.0ChiLan1.0
ZKSCAN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26117,934,934 - 117,969,044 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,199,568 - 166,233,676 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,050,741 - 92,080,554 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17105,484,170 - 105,514,778 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7105,484,185 - 105,502,895 (+)Ensemblpanpan1.1panPan2
ZKSCAN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl37,920,675 - 7,942,498 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.137,920,640 - 7,959,462 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.237,175,404 - 7,194,287 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZKSCAN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12813,013,603 - 13,064,154 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2813,044,616 - 13,056,332 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,207,048 - 3,237,799 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000010170   ⟹   ENSSTOP00000009123
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936543150,850 - 165,282 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000030025   ⟹   ENSSTOP00000015256
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936543180,662 - 192,238 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000040399   ⟹   ENSSTOP00000027452
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936543150,850 - 165,210 (+)Ensembl
RefSeq Acc Id: XM_005328431   ⟹   XP_005328488
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344133,844,331 - 133,855,242 (-)NCBI
SpeTri2.0NW_004936543181,359 - 192,197 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005328432   ⟹   XP_005328489
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344133,865,062 - 133,885,668 (-)NCBI
SpeTri2.0NW_004936543150,845 - 171,468 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013360068   ⟹   XP_013215522
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344133,844,331 - 133,885,668 (-)NCBI
SpeTri2.0NW_004936543150,845 - 192,197 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021728535   ⟹   XP_021584210
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344133,865,062 - 133,885,668 (-)NCBI
SpeTri2.0NW_004936543150,897 - 171,468 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005328489   ⟸   XM_005328432
- Peptide Label: isoform X1
- UniProtKB: I3MEZ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013215522   ⟸   XM_013360068
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_005328488   ⟸   XM_005328431
- Peptide Label: isoform X3
- UniProtKB: I3MT11 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021584210   ⟸   XM_021728535
- Peptide Label: isoform X2
- UniProtKB: A0A287D1Q5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000027452   ⟸   ENSSTOT00000040399
Ensembl Acc Id: ENSSTOP00000009123   ⟸   ENSSTOT00000010170
Ensembl Acc Id: ENSSTOP00000015256   ⟸   ENSSTOT00000030025
Protein Domains
C2H2-type   KRAB   SCAN box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000010173 Ensembl, UniProtKB/TrEMBL
  ENSSTOG00000021741 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000010170.3 UniProtKB/TrEMBL
  ENSSTOT00000030025.2 UniProtKB/TrEMBL
  ENSSTOT00000040399.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.4020.10 UniProtKB/TrEMBL
  6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  SCAN_dom UniProtKB/TrEMBL
  SCAN_sf UniProtKB/TrEMBL
  Zinc_finger UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene LOC101968831 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE PRDM9 UniProtKB/TrEMBL
  PR DOMAIN ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER AND SCAN DOMAIN-CONTAINING UniProtKB/TrEMBL
  ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 1 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  SCAN UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
  zf-H2C2_2 UniProtKB/TrEMBL
PROSITE KRAB UniProtKB/TrEMBL
  SCAN_BOX UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  SCAN UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP Retrovirus capsid dimerization domain-like UniProtKB/TrEMBL
  SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A287D1Q5 ENTREZGENE, UniProtKB/TrEMBL
  I3MEZ1 ENTREZGENE, UniProtKB/TrEMBL
  I3MT11 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-07-13 Zkscan1  zinc finger with KRAB and SCAN domains 1  LOC101968831  zinc finger protein with KRAB and SCAN domains 1  Symbol and/or name change 5135510 APPROVED