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Gene: Slbp (stem-loop histone mRNA binding protein) Ictidomys tridecemlineatus

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Symbol:

Slbp

Name:

stem-loop histone mRNA binding protein

RGD ID:

12509037

Description:

ENCODES a protein that exhibits histone pre-mRNA stem-loop binding (inferred); identical protein binding (inferred); mRNA binding (inferred); INVOLVED IN cap-dependent translational initiation (inferred); mRNA 3'-end processing by stem-loop binding and cleavage (inferred); mRNA transport (inferred); ASSOCIATED WITH cherubism (ortholog); coloboma (ortholog); optic atrophy (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); histone mRNA stem-loop binding complex (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC101974896

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	67,970,403 - 67,979,216 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936477	21,671,842 - 21,680,915 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936477	21,672,143 - 21,680,899 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slbp	Squirrel	cherubism		ISO	RGD:1350910	8554872	ClinVar Annotator: match by term: Fibrous dysplasia of jaw	ClinVar	PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slbp	Squirrel	coloboma		ISO	RGD:1350910	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:30695021
Slbp	Squirrel	optic atrophy		ISO	RGD:1350910	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:30695021
Slbp	Squirrel	Retinal Dysplasia		ISO	RGD:1350910	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:30695021

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slbp	Squirrel	cap-dependent translational initiation	involved_in	IEA	UniProtKB:Q14493\|ensembl:ENSP00000417686	150520179		Ensembl	GO_REF:0000107
Slbp	Squirrel	mRNA 3'-end processing by stem-loop binding and cleavage	involved_in	IEA	UniProtKB:P97440\|ensembl:ENSMUSP00000062930	150520179		Ensembl	GO_REF:0000107
Slbp	Squirrel	mRNA 3'-end processing by stem-loop binding and cleavage	involved_in	IEA	PANTHER:PTN000425782\|PANTHER:PTN000425788	150520179		TreeGrafter	GO_REF:0000118
Slbp	Squirrel	mRNA transport	involved_in	IEA	UniProtKB:Q14493\|ensembl:ENSP00000417686	150520179		Ensembl	GO_REF:0000107
Slbp	Squirrel	mRNA transport	involved_in	IEA	PANTHER:PTN000425782\|PANTHER:PTN000425788	150520179		TreeGrafter	GO_REF:0000118

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slbp	Squirrel	cytoplasm	located_in	IEA	UniProtKB:P97440\|UniProtKB:Q14493\|ensembl:ENSMUSP00000062930\|ensembl:ENSP00000417686	150520179		Ensembl	GO_REF:0000107
Slbp	Squirrel	cytoplasm	located_in	IEA	PANTHER:PTN000425782\|PANTHER:PTN000425788	150520179		TreeGrafter	GO_REF:0000118
Slbp	Squirrel	cytosol	located_in	IEA	UniProtKB:Q14493\|UniProtKB:Q53XR2\|ensembl:ENSP00000417686	150520179		Ensembl	GO_REF:0000107
Slbp	Squirrel	histone mRNA stem-loop binding complex	part_of	IEA	UniProtKB:Q14493\|ensembl:ENSP00000417686	150520179		Ensembl	GO_REF:0000107
Slbp	Squirrel	histone pre-mRNA 3'end processing complex	part_of	IEA	UniProtKB:P97440\|ensembl:ENSMUSP00000062930	150520179		Ensembl	GO_REF:0000107
Slbp	Squirrel	histone pre-mRNA 3'end processing complex	part_of	IEA	PANTHER:PTN000425782\|PANTHER:PTN000425788	150520179		TreeGrafter	GO_REF:0000118
Slbp	Squirrel	nucleolus	located_in	IEA	UniProtKB:Q14493\|UniProtKB:Q53XR2\|ensembl:ENSP00000417686	150520179		Ensembl	GO_REF:0000107
Slbp	Squirrel	nucleoplasm	located_in	IEA	UniProtKB:Q14493\|UniProtKB:Q53XR2\|ensembl:ENSP00000417686	150520179		Ensembl	GO_REF:0000107
Slbp	Squirrel	nucleus	located_in	IEA	UniProtKB:P97440\|UniProtKB:Q14493\|ensembl:ENSMUSP00000062930\|ensembl:ENSP00000417686	150520179		Ensembl	GO_REF:0000107
Slbp	Squirrel	ribonucleoprotein complex	part_of	IEA	UniProtKB:P97440\|ensembl:ENSMUSP00000062930	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slbp	Squirrel	histone pre-mRNA stem-loop binding	enables	IEA	PANTHER:PTN000425782\|PANTHER:PTN000425788	150520179		TreeGrafter	GO_REF:0000118
Slbp	Squirrel	histone pre-mRNA stem-loop binding	enables	IEA	UniProtKB:P97440\|ensembl:ENSMUSP00000062930	150520179		Ensembl	GO_REF:0000107
Slbp	Squirrel	identical protein binding	enables	IEA	UniProtKB:Q14493\|ensembl:ENSP00000417686	150520179		Ensembl	GO_REF:0000107
Slbp	Squirrel	mRNA binding	enables	IEA	InterPro:IPR026502	150520179		InterPro	GO_REF:0000002
Slbp	Squirrel	mRNA binding	enables	IEA	PANTHER:PTN000425782\|PANTHER:PTN000425788	150520179		TreeGrafter	GO_REF:0000118
Slbp	Squirrel	mRNA binding	enables	IEA	UniProtKB:P97440\|UniProtKB:Q14493\|ensembl:ENSMUSP00000062930\|ensembl:ENSP00000417686	150520179		Ensembl	GO_REF:0000107
Slbp	Squirrel	protein binding	enables	ISO	UniProtKB:Q8BJL1	9068941	PMID:30980108	MGI	PMID:30980108
Slbp	Squirrel	protein binding	enables	ISO	UniProtKB:O15116	9068941	PMID:18172165	UniProt	PMID:18172165
Slbp	Squirrel	protein binding	enables	ISO	UniProtKB:Q92900	9068941	PMID:16086026	IntAct	PMID:16086026
Slbp	Squirrel	protein binding	enables	ISO	UniProtKB:A9UHW6	9068941	PMID:23286197, PMID:23804756	IntAct	PMID:23286197\|PMID:23804756
Slbp	Squirrel	protein binding	enables	ISO	UniProtKB:Q9Y5L0	9068941	PMID:15829567	UniProt	PMID:15829567
Slbp	Squirrel	protein binding	enables	ISO	UniProtKB:Q8IV48	9068941	PMID:23329046	IntAct	PMID:23329046
Slbp	Squirrel	RNA binding	enables	IEA	UniProtKB-KW:KW-0694	150520179		UniProt	GO_REF:0000043
Slbp	Squirrel	RNA binding	enables	IEA	InterPro:IPR029344	150520179		InterPro	GO_REF:0000002

PMID:30032202

Slbp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	67,970,403 - 67,979,216 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936477	21,671,842 - 21,680,915 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936477	21,672,143 - 21,680,899 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLBP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	1,692,731 - 1,712,319 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	1,692,731 - 1,712,344 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	1,694,458 - 1,714,046 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	1,664,325 - 1,683,828 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	1,661,757 - 1,681,261	NCBI
Celera	4	1,605,626 - 1,625,082 (-)	NCBI		Celera
Cytogenetic Map	4	p16.3	NCBI
HuRef	4	1,637,465 - 1,656,925 (-)	NCBI		HuRef
CHM1_1	4	1,692,305 - 1,711,989 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	1,690,606 - 1,710,149 (-)	NCBI		T2T-CHM13v2.0

Slbp
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	33,797,399 - 33,809,918 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	33,792,296 - 33,809,918 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	33,640,055 - 33,652,574 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	33,634,952 - 33,652,574 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	33,982,711 - 33,994,955 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	33,956,919 - 33,969,163 (-)	NCBI		MGSCv36	mm8
Celera	5	31,116,183 - 31,128,422 (-)	NCBI		Celera
Cytogenetic Map	5	B2	NCBI
cM Map	5	17.83	NCBI

Slbp
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	81,295,479 - 81,306,446 (+)	NCBI		GRCr8
mRatBN7.2	14	77,071,441 - 77,081,911 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	77,071,632 - 77,081,906 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	81,524,007 - 81,534,181 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	82,764,607 - 82,774,784 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	79,209,907 - 79,220,082 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	82,356,916 - 82,366,368 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	82,356,916 - 82,366,368 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	83,046,030 - 83,056,021 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	82,767,415 - 82,778,030 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	14	75,995,251 - 76,005,216 (+)	NCBI		Celera
Cytogenetic Map	14	q21	NCBI

Slbp
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955514	955,296 - 967,327 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955514	954,489 - 968,670 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLBP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	2,021,762 - 2,041,101 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	1,956,969 - 1,976,729 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	1,830,247 - 1,849,890 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	1,744,612 - 1,772,962 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	1,744,616 - 1,763,796 (-)	Ensembl	panpan1.1		panPan2

SLBP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	62,386,982 - 62,401,541 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	62,386,977 - 62,400,891 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	64,904,699 - 64,919,261 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	62,862,384 - 62,876,780 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	62,862,384 - 62,876,763 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	62,355,910 - 62,370,480 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	62,559,430 - 62,573,999 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	62,918,670 - 62,933,236 (+)	NCBI		UU_Cfam_GSD_1.0

SLBP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	802,940 - 818,216 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	802,940 - 818,161 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	321,600 - 332,488 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLBP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	27	47,054,154 - 47,075,104 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	27	47,054,787 - 47,074,537 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666051	3,430,870 - 3,451,975 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slbp
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624755	25,699,977 - 25,714,348 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:50191219-58535818)x3	copy number gain	See cases [RCV000050883]	Chr19:50191219..58535818 [GRCh38] Chr19:50694476..59047185 [GRCh37] Chr19:55386288..63738997 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:49907832-58557889)x3	copy number gain	See cases [RCV000052925]	Chr19:49907832..58557889 [GRCh38] Chr19:50411089..59069256 [GRCh37] Chr19:55102901..63761068 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:51141518-58539965)x3	copy number gain	See cases [RCV000052926]	Chr19:51141518..58539965 [GRCh38] Chr19:51644775..59051332 [GRCh37] Chr19:56336587..63743144 [NCBI36] Chr19:19q13.41-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3	copy number gain	See cases [RCV000052914]	Chr19:47908540..58539965 [GRCh38] Chr19:48411797..59051332 [GRCh37] Chr19:53103609..63743144 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3	copy number gain	See cases [RCV000052915]	Chr19:47929575..58572206 [GRCh38] Chr19:48432832..59083573 [GRCh37] Chr19:53124644..63775385 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:50152520-58581203)x3	copy number gain	See cases [RCV000135843]	Chr19:50152520..58581203 [GRCh38] Chr19:50655777..59092570 [GRCh37] Chr19:55347589..63784382 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.41(chr19:51202361-51993020)x3	copy number gain	See cases [RCV000143450]	Chr19:51202361..51993020 [GRCh38] Chr19:51705617..52496273 [GRCh37] Chr19:56397429..57188085 [NCBI36] Chr19:19q13.41	uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:50489390-59095359)x3	copy number gain	See cases [RCV000445925]	Chr19:50489390..59095359 [GRCh37] Chr19:19q13.33-13.43	pathogenic
NM_007147.4(ZNF175):c.1460A>G (p.Lys487Arg)	single nucleotide variant	not specified [RCV004293322]	Chr19:51587791 [GRCh38] Chr19:52091044 [GRCh37] Chr19:19q13.41	uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3	copy number gain	See cases [RCV000511289]	Chr19:260912..58956888 [GRCh37] Chr19:19p13.3-q13.43	pathogenic\|uncertain significance
NM_007147.4(ZNF175):c.100G>A (p.Val34Met)	single nucleotide variant	not specified [RCV004297924]	Chr19:51581418 [GRCh38] Chr19:52084671 [GRCh37] Chr19:19q13.41	likely benign
NM_007147.4(ZNF175):c.1467G>C (p.Gln489His)	single nucleotide variant	not specified [RCV004304750]	Chr19:51587798 [GRCh38] Chr19:52091051 [GRCh37] Chr19:19q13.41	uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)	copy number gain	See cases [RCV000512296]	Chr19:260912..58956888 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3	copy number gain	not provided [RCV000752444]	Chr19:260912..59097160 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3	copy number gain	not provided [RCV000752439]	Chr19:68029..59110290 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:50740074-59097160)x3	copy number gain	not provided [RCV000740208]	Chr19:50740074..59097160 [GRCh37] Chr19:19q13.33-13.43	pathogenic
GRCh37/hg19 19q13.31-13.42(chr19:44738088-53621561)x3	copy number gain	not provided [RCV001007050]	Chr19:44738088..53621561 [GRCh37] Chr19:19q13.31-13.42	pathogenic
NM_007147.4(ZNF175):c.638G>T (p.Gly213Val)	single nucleotide variant	not specified [RCV004322781]	Chr19:51586969 [GRCh38] Chr19:52090222 [GRCh37] Chr19:19q13.41	uncertain significance
GRCh37/hg19 19q13.32-13.42(chr19:47939842-54626871)	copy number gain	not provided [RCV001249294]	Chr19:47939842..54626871 [GRCh37] Chr19:19q13.32-13.42	not provided
GRCh37/hg19 19q13.33-13.43(chr19:48463931-57095254)x3	copy number gain	not provided [RCV001259944]	Chr19:48463931..57095254 [GRCh37] Chr19:19q13.33-13.43	pathogenic
GRCh37/hg19 19q13.33-13.41(chr19:49911081-53127438)	copy number gain	not specified [RCV002052689]	Chr19:49911081..53127438 [GRCh37] Chr19:19q13.33-13.41	likely pathogenic
GRCh37/hg19 19q13.41(chr19:51769834-52415762)x3	copy number gain	not provided [RCV001827892]	Chr19:51769834..52415762 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1574A>T (p.His525Leu)	single nucleotide variant	not specified [RCV004307962]	Chr19:51587905 [GRCh38] Chr19:52091158 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1904G>T (p.Arg635Ile)	single nucleotide variant	not specified [RCV004122512]	Chr19:51588235 [GRCh38] Chr19:52091488 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1363G>A (p.Ala455Thr)	single nucleotide variant	not specified [RCV004085977]	Chr19:51587694 [GRCh38] Chr19:52090947 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.2045A>G (p.Asn682Ser)	single nucleotide variant	not specified [RCV004134130]	Chr19:51588376 [GRCh38] Chr19:52091629 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.158G>A (p.Arg53Gln)	single nucleotide variant	not specified [RCV004137818]	Chr19:51581476 [GRCh38] Chr19:52084729 [GRCh37] Chr19:19q13.41	likely benign
NM_007147.4(ZNF175):c.676G>T (p.Val226Phe)	single nucleotide variant	not specified [RCV004147876]	Chr19:51587007 [GRCh38] Chr19:52090260 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1747G>A (p.Gly583Ser)	single nucleotide variant	not specified [RCV004116663]	Chr19:51588078 [GRCh38] Chr19:52091331 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1400G>T (p.Arg467Ile)	single nucleotide variant	not specified [RCV004180201]	Chr19:51587731 [GRCh38] Chr19:52090984 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1615G>A (p.Ala539Thr)	single nucleotide variant	not specified [RCV004205762]	Chr19:51587946 [GRCh38] Chr19:52091199 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.193G>T (p.Ala65Ser)	single nucleotide variant	not specified [RCV004184250]	Chr19:51581511 [GRCh38] Chr19:52084764 [GRCh37] Chr19:19q13.41	likely benign
NM_007147.4(ZNF175):c.1027G>T (p.Val343Phe)	single nucleotide variant	not specified [RCV004214674]	Chr19:51587358 [GRCh38] Chr19:52090611 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1125G>A (p.Met375Ile)	single nucleotide variant	not specified [RCV004132998]	Chr19:51587456 [GRCh38] Chr19:52090709 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.70G>A (p.Glu24Lys)	single nucleotide variant	not specified [RCV004173536]	Chr19:51573399 [GRCh38] Chr19:52076652 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.802A>G (p.Lys268Glu)	single nucleotide variant	not specified [RCV004165823]	Chr19:51587133 [GRCh38] Chr19:52090386 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.284A>G (p.Gln95Arg)	single nucleotide variant	not specified [RCV004236756]	Chr19:51581871 [GRCh38] Chr19:52085124 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1760A>G (p.Tyr587Cys)	single nucleotide variant	not specified [RCV004097909]	Chr19:51588091 [GRCh38] Chr19:52091344 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1918G>A (p.Glu640Lys)	single nucleotide variant	not specified [RCV004191022]	Chr19:51588249 [GRCh38] Chr19:52091502 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.680T>C (p.Val227Ala)	single nucleotide variant	not specified [RCV004175453]	Chr19:51587011 [GRCh38] Chr19:52090264 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1309C>T (p.His437Tyr)	single nucleotide variant	not specified [RCV004176388]	Chr19:51587640 [GRCh38] Chr19:52090893 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.653A>G (p.Asn218Ser)	single nucleotide variant	not specified [RCV004238471]	Chr19:51586984 [GRCh38] Chr19:52090237 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.544A>G (p.Ile182Val)	single nucleotide variant	not specified [RCV004274032]	Chr19:51586875 [GRCh38] Chr19:52090128 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1103G>A (p.Cys368Tyr)	single nucleotide variant	not specified [RCV004276161]	Chr19:51587434 [GRCh38] Chr19:52090687 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.36G>C (p.Gln12His)	single nucleotide variant	not specified [RCV004267969]	Chr19:51573365 [GRCh38] Chr19:52076618 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.767A>G (p.Gln256Arg)	single nucleotide variant	not specified [RCV004253782]	Chr19:51587098 [GRCh38] Chr19:52090351 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1745C>G (p.Thr582Arg)	single nucleotide variant	not specified [RCV004319040]	Chr19:51588076 [GRCh38] Chr19:52091329 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1988G>A (p.Arg663Gln)	single nucleotide variant	not specified [RCV004309574]	Chr19:51588319 [GRCh38] Chr19:52091572 [GRCh37] Chr19:19q13.41	uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:49625130-57647352)x3	copy number gain	not provided [RCV003485200]	Chr19:49625130..57647352 [GRCh37] Chr19:19q13.33-13.43	likely pathogenic
NM_007147.4(ZNF175):c.1351G>A (p.Glu451Lys)	single nucleotide variant	not specified [RCV004491553]	Chr19:51587682 [GRCh38] Chr19:52090935 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.158G>C (p.Arg53Pro)	single nucleotide variant	not specified [RCV004491554]	Chr19:51581476 [GRCh38] Chr19:52084729 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1670A>C (p.Lys557Thr)	single nucleotide variant	not specified [RCV004491556]	Chr19:51588001 [GRCh38] Chr19:52091254 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.676G>A (p.Val226Ile)	single nucleotide variant	not specified [RCV004491561]	Chr19:51587007 [GRCh38] Chr19:52090260 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.781T>C (p.Cys261Arg)	single nucleotide variant	not specified [RCV004491562]	Chr19:51587112 [GRCh38] Chr19:52090365 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1975A>G (p.Lys659Glu)	single nucleotide variant	not specified [RCV004491558]	Chr19:51588306 [GRCh38] Chr19:52091559 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.2065C>T (p.His689Tyr)	single nucleotide variant	not specified [RCV004491560]	Chr19:51588396 [GRCh38] Chr19:52091649 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.851G>A (p.Cys284Tyr)	single nucleotide variant	not specified [RCV004491563]	Chr19:51587182 [GRCh38] Chr19:52090435 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1652G>A (p.Arg551Lys)	single nucleotide variant	not specified [RCV004491555]	Chr19:51587983 [GRCh38] Chr19:52091236 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.203A>T (p.Tyr68Phe)	single nucleotide variant	not specified [RCV004491559]	Chr19:51581790 [GRCh38] Chr19:52085043 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.709T>C (p.Ser237Pro)	single nucleotide variant	not specified [RCV004687556]	Chr19:51587040 [GRCh38] Chr19:52090293 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1289A>G (p.Gln430Arg)	single nucleotide variant	not specified [RCV004687559]	Chr19:51587620 [GRCh38] Chr19:52090873 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1274G>C (p.Gly425Ala)	single nucleotide variant	not specified [RCV004688058]	Chr19:51587605 [GRCh38] Chr19:52090858 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.2054A>G (p.Asn685Ser)	single nucleotide variant	not specified [RCV004687555]	Chr19:51588385 [GRCh38] Chr19:52091638 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1382A>G (p.His461Arg)	single nucleotide variant	not specified [RCV004687557]	Chr19:51587713 [GRCh38] Chr19:52090966 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.994G>T (p.Asp332Tyr)	single nucleotide variant	not specified [RCV004687553]	Chr19:51587325 [GRCh38] Chr19:52090578 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.431G>A (p.Arg144His)	single nucleotide variant	not specified [RCV004688057]	Chr19:51586762 [GRCh38] Chr19:52090015 [GRCh37] Chr19:19q13.41	likely benign
NM_007147.4(ZNF175):c.383A>G (p.Asp128Gly)	single nucleotide variant	not specified [RCV004687558]	Chr19:51586714 [GRCh38] Chr19:52089967 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.853G>T (p.Gly285Trp)	single nucleotide variant	not specified [RCV004687554]	Chr19:51587184 [GRCh38] Chr19:52090437 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.749C>T (p.Thr250Ile)	single nucleotide variant	not specified [RCV004886110]	Chr19:51587080 [GRCh38] Chr19:52090333 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1277A>T (p.Lys426Ile)	single nucleotide variant	not specified [RCV004886113]	Chr19:51587608 [GRCh38] Chr19:52090861 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1355G>A (p.Cys452Tyr)	single nucleotide variant	not specified [RCV004886109]	Chr19:51587686 [GRCh38] Chr19:52090939 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.557C>T (p.Pro186Leu)	single nucleotide variant	not specified [RCV004886115]	Chr19:51586888 [GRCh38] Chr19:52090141 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.363G>T (p.Met121Ile)	single nucleotide variant	not specified [RCV004886119]	Chr19:51586694 [GRCh38] Chr19:52089947 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.301G>A (p.Glu101Lys)	single nucleotide variant	not specified [RCV004886111]	Chr19:51586632 [GRCh38] Chr19:52089885 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.679G>T (p.Val227Phe)	single nucleotide variant	not specified [RCV004886112]	Chr19:51587010 [GRCh38] Chr19:52090263 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.789T>G (p.His263Gln)	single nucleotide variant	not specified [RCV004886114]	Chr19:51587120 [GRCh38] Chr19:52090373 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1390G>T (p.Val464Phe)	single nucleotide variant	not specified [RCV004886116]	Chr19:51587721 [GRCh38] Chr19:52090974 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.101T>C (p.Val34Ala)	single nucleotide variant	not specified [RCV004886118]	Chr19:51581419 [GRCh38] Chr19:52084672 [GRCh37] Chr19:19q13.41	uncertain significance

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_005319039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000003258 ⟹ ENSSTOP00000002910

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936477	21,672,192 - 21,680,110 (+)	Ensembl

Ensembl Acc Id:

ENSSTOT00000030498 ⟹ ENSSTOP00000025519

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936477	21,671,842 - 21,680,915 (+)	Ensembl

RefSeq Acc Id:

XM_005319039 ⟹ XP_005319096

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405285	67,970,403 - 67,979,216 (+)	NCBI
SpeTri2.0	NW_004936477	21,672,143 - 21,680,899 (+)	NCBI

Sequence:

show sequence

AGAGCCTGTTCGCGCCGGCGCCGATCACGCTGACGCCGTCCCTGCCGCCATGGCTTGTCGGCCGCGAAGCCCGCCTGCCTACGGGAGCCGCCGCGACCGCGGCGCTAGCCCGTCGTCCCCTAAGAGAT
GGAGCCTCGGGCGGAAGCGCAGAGCGGACGGGAGGCGCAGGAAGCCCGAGGACGCGGAGGAGGGCCAGCACCCGGCTGATGACCGCAGACCCGCGAGTTTCACCACTCCTGAAGGCCCCAAGCCCCGT
TCTCGGTGTTCAGACTGGGCCAATGCCGTTGAAGAAGATGAAATGAGGACCAGAGTTAACAAAGAAATTGCAAGATATAAAAGAAAACTCCTCATAAATGACTTTGGAAGAGAACGGAAATCATCATC
AGGAAGTTCTGATTCAAAAGAGTCAGCGTCTACAGTGCCAGCTGATGTGGAGACTGATGAAAGTGTCCTGATGCGAAGACAGAAGCAGATCAACTATGGAAAGAACACTATTGCCTACGATCGCTATA
TTAAAGAAGTCCCCAGACACCTTCGACAACCTGGCATTCACCCCAAGACCCCCAACAAATTTAAGAAGTATAGTCGGCGATCATGGGACCAGCAGATCAAGCTCTGGAAGGTGGCTCTGCACTTCTGG
GATCCTCCAGCTGAAGAAGGCTGTGATTTGCAAGAAATACACCCTGTGGACCTTGGGGAAATGGAAACTGAATCCACAGAGAGCAGCTCTGAGTCCCAGACGAGCTCACAGGATAACTTTGATGCGTA
TTCTGGCACACCCACCAAGGTCAGACACGTGGACTGCCAAGTGGAAGACGAATTTGATTTGGAAGCTTGCTTAACTGAGCCCTTGAAAGACTTCTCTGCTATGAGTTGACTGCCACCTGGTGGCCACT
GGGAGAAGCAGGTGCCATCTCTGGCCGCGTAGAGGTCGGCCAAACATGTAGGCCTGTGATGTGCACTGGTAGCTGGGTGGTGTCTGTCAGTAGTTCATGGTCTTAGGATGAGTTGTTGTTCTTGCCTT
ACTTTCTTAGAAACATTAATTTTGTGTATAGTGAATGTTTTGCATGTTTTAACTTGTAAATGGTGCTGAATCCAAGGAATATTGATTGCAAAGCAGTCTTGAGCAAACTTGGGTGCATGGTGTTTCCA
CTCTCAAGTTGGAAAGGCCAGTGCAAGTGAACTTGTTTCCCACAGCCTCCTTAGACTTTTAGTTGCCGCTTGTCAGGTGGGCTGGTTGTAAACTTTACCATGTGTTCTTAGGACCAATATAGGGTGGT
TTTCTTTGCAGGTACTTGACAAAGTATATTCAGTGTGAGACATATGATGATTTTGTGGAAATGTGTTTTCTGGCCTTTTATCAATAAGTCCAAGTAGTTTTTTCCCTCCCATACAGAGCTCTGAACAA
AGATGTTAAATTAATGGGTTTTATGTAAGTTAAAGTCTCTGATTGGGTACTTGTAAATAGCACTAGGTAGGTCTTAACTGATGAGACAGTTAAGGCAACAGAGTGACTTAGAATGTTTTTTACAATCA
GTTAATTGACAGTGTAAAATTACTGTAAATGATAATGTGTACAGATATTCAATTGTAAACTTGTTAAACTGTTGTGTTTTCATTGCTTTTGTATGGAATGATGTTGCAAAAATAAAAAGGAAAAAACT
CT

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Protein RefSeqs	XP_005319096	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000002910.3
	ENSSTOP00000025519.1
GenBank Protein	KAG3277067	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005319096 ⟸ XM_005319039

- UniProtKB:

A0A287CW77 (UniProtKB/TrEMBL), I3M1Y3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MACRPRSPPAYGSRRDRGASPSSPKRWSLGRKRRADGRRRKPEDAEEGQHPADDRRPASFTTPEGPKPRSRCSDWANAVEEDEMRTRVNKEIARYKRKLLINDFGRERKSSSGSSDSKESASTVPADV
ETDESVLMRRQKQINYGKNTIAYDRYIKEVPRHLRQPGIHPKTPNKFKKYSRRSWDQQIKLWKVALHFWDPPAEEGCDLQEIHPVDLGEMETESTESSSESQTSSQDNFDAYSGTPTKVRHVDCQVED
EFDLEACLTEPLKDFSAMS

hide sequence

Ensembl Acc Id:

ENSSTOP00000002910 ⟸ ENSSTOT00000003258

Ensembl Acc Id:

ENSSTOP00000025519 ⟸ ENSSTOT00000030498

Protein Domains

Histone RNA hairpin-binding protein RNA-binding

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000003262	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000003258.3	UniProtKB/TrEMBL
	ENSSTOT00000030498.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.8.1120	UniProtKB/TrEMBL
InterPro	SLBP1/SLBP2	UniProtKB/TrEMBL
	SLBP_RNA_bind	UniProtKB/TrEMBL
	SLBP_RNA_bind_sf	UniProtKB/TrEMBL
NCBI Gene	Slbp	ENTREZGENE
PANTHER	HISTONE RNA HAIRPIN-BINDING PROTEIN	UniProtKB/TrEMBL
	PTHR17408	UniProtKB/TrEMBL
Pfam	SLBP_RNA_bind	UniProtKB/TrEMBL
UniProt	A0A287CW77	ENTREZGENE, UniProtKB/TrEMBL
	I3M1Y3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-07-11	Slbp	stem-loop histone mRNA binding protein	Slbp	stem-loop binding protein	Symbol and/or name change	5135510	APPROVED
2022-08-09	Slbp	stem-loop binding protein	LOC101974896	stem-loop binding protein	Symbol and/or name change	5135510	APPROVED
2021-03-26	LOC101974896	stem-loop binding protein	Slbp	stem-loop binding protein	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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