Advanced Search (OLGA)

Gene: Fbxw4 (F-box and WD repeat domain containing 4) Ictidomys tridecemlineatus

Analyze

Symbol:

Fbxw4

Name:

F-box and WD repeat domain containing 4

RGD ID:

12474207

Description:

INVOLVED IN cartilage development (ortholog); embryonic digit morphogenesis (ortholog); limb development (ortholog); ASSOCIATED WITH HYPOPLASTIC FEMURS AND PELVIS (ortholog); split hand-foot malformation (ortholog); split hand-foot malformation 3 (ortholog); FOUND IN SCF ubiquitin ligase complex (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

F-box and WD repeat domain containing 4, transcript variant X1; F-box and WD repeat domain containing 4, transcript variant X2; F-box and WD repeat domain containing 4, transcript variant X3; F-box and WD repeat domain containing 4, transcript variant X4; F-box/WD repeat-containing protein 4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	32,469,518 - 32,558,996 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936600	4,073,384 - 4,161,588 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936600	4,072,749 - 4,162,220 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

HYPOPLASTIC FEMURS AND PELVIS (ISO)

split hand-foot malformation (ISO)

split hand-foot malformation 3 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cartilage development (IEA,ISO)

embryonic digit morphogenesis (IEA,ISO)

limb development (IEA,ISO)

positive regulation of mesenchymal cell proliferation (IEA,ISO)

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (IEA)

Cellular Component

SCF ubiquitin ligase complex (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Fbxw4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	32,469,518 - 32,558,996 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936600	4,073,384 - 4,161,588 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936600	4,072,749 - 4,162,220 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FBXW4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	101,610,666 - 101,695,295 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	101,610,664 - 101,695,295 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	103,370,423 - 103,455,052 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	103,360,411 - 103,444,733 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	10	97,109,207 - 97,193,536 (-)	NCBI		Celera
Cytogenetic Map	10	q24.32	NCBI
HuRef	10	97,000,717 - 97,084,921 (-)	NCBI		HuRef
CHM1_1	10	103,654,100 - 103,738,441 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	102,494,739 - 102,578,296 (-)	NCBI		T2T-CHM13v2.0

Fbxw4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	45,566,693 - 45,648,954 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	45,566,693 - 45,648,751 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	45,578,254 - 45,660,520 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	45,578,254 - 45,660,312 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	45,652,747 - 45,734,683 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	45,631,568 - 45,713,504 (-)	NCBI		MGSCv36	mm8
Celera	19	46,345,905 - 46,428,364 (-)	NCBI		Celera
Cytogenetic Map	19	C3	NCBI
cM Map	19	38.75	NCBI

Fbxw4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	254,375,921 - 254,465,173 (-)	NCBI		GRCr8
mRatBN7.2	1	244,426,892 - 244,514,188 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	244,426,896 - 244,514,163 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	252,568,588 - 252,655,050 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	259,271,799 - 259,352,963 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	251,918,142 - 252,005,105 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	265,318,526 - 265,420,503 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	265,318,526 - 265,420,503 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	270,474,853 - 270,499,913 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	250,746,869 - 250,874,460 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	251,007,474 - 251,135,492 (-)	NCBI
Celera	1	240,235,760 - 240,322,798 (-)	NCBI		Celera
Cytogenetic Map	1	q54	NCBI

Fbxw4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955485	8,584,836 - 8,669,705 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955485	8,584,836 - 8,688,416 (+)	NCBI	ChiLan1.0	ChiLan1.0

FBXW4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	113,496,596 - 113,581,162 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	113,501,913 - 113,586,510 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	98,212,907 - 98,297,477 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	101,685,804 - 101,769,277 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	101,685,804 - 101,769,672 (-)	Ensembl	panpan1.1		panPan2

FBXW4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	14,219,724 - 14,336,846 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	14,219,893 - 14,301,924 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	14,388,454 - 14,505,308 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	14,687,904 - 14,804,731 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	14,688,073 - 14,769,794 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	14,232,621 - 14,351,242 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	14,274,140 - 14,390,820 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	14,406,279 - 14,523,118 (-)	NCBI		UU_Cfam_GSD_1.0

FBXW4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	112,638,204 - 112,736,056 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	112,628,988 - 112,736,631 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	122,381,573 - 122,481,033 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FBXW4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	94,634,721 - 94,722,156 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	94,635,347 - 94,721,439 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	55,710,938 - 55,797,860 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fbxw4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624831	1,107,689 - 1,183,958 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624831	1,107,689 - 1,183,839 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005333656	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021731877	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021731878	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021731879	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010002273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000011494 ⟹ ENSSTOP00000010315

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936600	4,073,384 - 4,161,588 (+)	Ensembl

RefSeq Acc Id:

XM_005333656 ⟹ XP_005333713

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	32,469,555 - 32,558,996 (+)	NCBI
SpeTri2.0	NW_004936600	4,072,780 - 4,162,220 (+)	NCBI

Sequence:

show sequence

CTCCACTGCCTCAGGTGTGAGGGGCGGGCCTAGGCCTCAGCCCGCGCCGCCCCATGTGACCCGG
TCCGACATGGTGTCGCCTCCTCCCGGGGCGGCGGCGGTGGCTCGGGCTCGGCTCCACGTTGGGC
CGGCCCCGCGGCCGCTCATGGGCAGCCAAGGCCGCTCGGGAACCCCCGGGAACAGCGGGCCGGG
CGAGGGCGAGGGCGGGGAGACCAGGGAACTGCAGGAAGCGAGGGTCGTGCGGGGGAAGCGAAGG
AAGGGGAAGGGAAAAGCCGGCGCAGGGCAAGGCGGAAGAGGAAGCGGGGCGGAAGGGAAGCCGG
GGCTGCAGCAGGCGCAGGAGGCTGCGGGGTCGTGGGTAGAGGCAGAAGCTGGGGCAGGCCCGGG
ACGGGACTCAGAGGGAGGCGGAAGCGTGGAGGAAGGAGCGGGAAGCATCGAGAAGGGAGATGAA
GGGAGCACAGGGGCTGGGAAGGAGGCACAAGGAAGACTTGATGGGAAAGAGGAGGAACGGAGAG
GCAGGACTGGGCGGCGGGAGGATGCCAGGCCGGGGAAAGCACAGGGACAAGACGGTCAGGCTTG
GGGCGGCATCGCAGGGACAGGAGCGGCCATGGCGGCGGCAGCCGAGGAGGAAGCGGCGGCTCGG
GAGCCCGCTGCTCGGCCGGCTGCAGGGCCCGCGCTCTGGCGCCTGCCCGAGGAGCTGCTGCTGC
TCATCTGCTCCTACCTGGACATGCGGGCCCTCGGCCGCCTGGCGCAAGTGTGCCGCTGGCTGCG
GCGCTTCACCAGCTGCGACCTGCTCTGGCGCCGGATAGCCCGGGCCTCGCTCAACTCCGGCTTC
ACGCGGCTCGGCACCGACCTGATGAGCAATGTCCCAGTGAAGGAACGGGTGAAGGTGTCCCAGA
ACTGGAGGCTGGGGCGCTGCCGAGAGGGGATTCTGCTCAAGTGGAGGTGCAGTCAGATGCCCTG
GATGCAGCTAGAGGATGATTCTCTGTACATATCCCAAGCTAATTTCATCCTGGCCTACAAGTTC
CGCCCAGATGGTGCCAGCTTGAATCGTCGGCCCTTGGGAGTCTTCGCTGGGCATGATGAGGATG
TTTGTCACTTTGTGCTGGCCAACTCACATATTATCAGTGCAGGAGGAGATGGGAAGATTGGTGT
CCATAAGATTCACAGCACCTTCACTGTCAAGTACTCGGCTCATGAACAGGAGGTGAATTGTGTG
GACTGCAAGGGGGGCATCATTGTGAGTGGCTCCAGGGACAGGACGGCCAAGGTATGGCCTTTGG
CCTCAGGCCGACTGGGGCAGTGCTTACACACCATCCAGACTGAAGACAGAGTTTGGTCCATTGC
TATCAGCCCATTGCTCAGCTCTTTTGTGACAGGGACAGCTTGTTGTGGGCACTTCTCACCCCTA
AGAATCTGGGACCTCAACAGTGGGCAGCTCATGACACACCTGGGCAGTGACTTTCCACCAGGGG
CTGGGGTGCTAGATGTCATGTATGAGTCCCCTTCCACACTGCTGTCCTGTGGCTACGACACCTA
TGTTCGTTACTGGGACCTCCGCACTAGTGTCCGAAAATGTGTCATGGAGTGGGAAGAACCCCAC
GACAGCACCCTGTACTGCTTGCAGACAGATGGCAACCACTTGCTGGCCACAGGGTCCTCCTACT
ATGGTGTTGTGCGGCTATGGGACCGGCGTCAGAGGGCCTGCCTGCACGCCTTCCCGCTGACATC
TACCCCACTCAGCAGTCCCGTATACTGCCTACGGTTCACCACCAAGCATCTCTATGCTGCACTG
TCCTACAACCTCCACGTCCTGGACTTTCAAAACCCATGACAGGCCACCCTGCCTGCCGGCCAGG
GGAGTCAGCTACTCAGGGACCTCTTTTGCTTGGAGGGTGCAGTGATACCTCCTTCCACCACCCC
TACTGTGCTCCTAGACTTATTGCCACAGTGTTCAGGTGTCTGAAGCTAGAGGCCATGGCTCCTG
GGGTACCAGGGCTCACCTAAGGATACAGCCCCTCCCAGAACCAGTGGAGGCACAGGACCTGCTG
CTCTGGGAGAATGCAACTGAACCCGTGGCCTTGCACCCATCTTACCAGAGCAAGGACCTAGCCT
GGAAAGGCCAATCCTGCCACCATGTCTTCATAGGGCCATGGCAGCCTCAGAGTGAGGTGAGGCA
CTCTAGCCTTTGCAGCTGGCCCCTTTCTGCCCTTCCCTGGAAGGAGAGGTAAGGCTGCCAGTGT
TCCTGCTGGCACCAACCAATCCTCAGACTCCACCTTTGACCAACCTCTTAGGGCTGTGAGCTCA
TTCCTAGGACAATGTGACCTAGTTTTGCTTTGAAGCCAAGAAAGGACAAAGGGAACCTAGCAGT
TTTGAGTGAGTTCTGAGCTAGCCCTACCTCAGGCCAGCTGTGGAGATATGCTATTCTTTTCATT
TTTGTAAAAATAAAGCTTGATTGTTCACAGA

hide sequence

RefSeq Acc Id:

XM_021731879 ⟹ XP_021587554

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	32,469,518 - 32,558,993 (+)	NCBI
SpeTri2.0	NW_004936600	4,072,749 - 4,162,220 (+)	NCBI

Sequence:

show sequence

TGTCAGCGCTCAGGCCCGCACCCCGAAGTGGCTCCACTGCCTCAGGATGAGCAATGTCCCAGTG
AAGGAACGGGTGAAGGTGTCCCAGAACTGGAGGCTGGGGCGCTGCCGAGAGGGGATTCTGCTCA
AGTGGAGGTGCAGTCAGATGCCCTGGATGCAGCTAGAGGATGATTCTCTGTACATATCCCAAGC
TAATTTCATCCTGGCCTACAAGTTCCGCCCAGATGGTGCCAGCTTGAATCGTCGGCCCTTGGGA
GTCTTCGCTGGGCATGATGAGGATGTTTGTCACTTTGTGCTGGCCAACTCACATATTATCAGTG
CAGGAGGAGATGGGAAGATTGGTGTCCATAAGATTCACAGCACCTTCACTGTCAAGTACTCGGC
TCATGAACAGGAGGTGAATTGTGTGGACTGCAAGGGGGGCATCATTGTGAGTGGCTCCAGGGAC
AGGACGGCCAAGGTATGGCCTTTGGCCTCAGGCCGACTGGGGCAGTGCTTACACACCATCCAGA
CTGAAGACAGAGTTTGGTCCATTGCTATCAGCCCATTGCTCAGCTCTTTTGTGACAGGGACAGC
TTGTTGTGGGCACTTCTCACCCCTAAGAATCTGGGACCTCAACAGTGGGCAGCTCATGACACAC
CTGGGCAGTGACTTTCCACCAGGGGCTGGGGTGCTAGATGTCATGTATGAGTCCCCTTCCACAC
TGCTGTCCTGTGGCTACGACACCTATGTTCGTTACTGGGACCTCCGCACTAGTGTCCGAAAATG
TGTCATGGAGTGGGAAGAACCCCACGACAGCACCCTGTACTGCTTGCAGACAGATGGCAACCAC
TTGCTGGCCACAGGGTCCTCCTACTATGGTGTTGTGCGGCTATGGGACCGGCGTCAGAGGGCCT
GCCTGCACGCCTTCCCGCTGACATCTACCCCACTCAGCAGTCCCGTATACTGCCTACGGTTCAC
CACCAAGCATCTCTATGCTGCACTGTCCTACAACCTCCACGTCCTGGACTTTCAAAACCCATGA
CAGGCCACCCTGCCTGCCGGCCAGGGGAGTCAGCTACTCAGGGACCTCTTTTGCTTGGAGGGTG
CAGTGATACCTCCTTCCACCACCCCTACTGTGCTCCTAGACTTATTGCCACAGTGTTCAGGTGT
CTGAAGCTAGAGGCCATGGCTCCTGGGGTACCAGGGCTCACCTAAGGATACAGCCCCTCCCAGA
ACCAGTGGAGGCACAGGACCTGCTGCTCTGGGAGAATGCAACTGAACCCGTGGCCTTGCACCCA
TCTTACCAGAGCAAGGACCTAGCCTGGAAAGGCCAATCCTGCCACCATGTCTTCATAGGGCCAT
GGCAGCCTCAGAGTGAGGTGAGGCACTCTAGCCTTTGCAGCTGGCCCCTTTCTGCCCTTCCCTG
GAAGGAGAGGTAAGGCTGCCAGTGTTCCTGCTGGCACCAACCAATCCTCAGACTCCACCTTTGA
CCAACCTCTTAGGGCTGTGAGCTCATTCCTAGGACAATGTGACCTAGTTTTGCTTTGAAGCCAA
GAAAGGACAAAGGGAACCTAGCAGTTTTGAGTGAGTTCTGAGCTAGCCCTACCTCAGGCCAGCT
GTGGAGATATGCTATTCTTTTCATTTTTGTAAAAATAAAGCTTGATTGTTCACAGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005333713	(Get FASTA)	NCBI Sequence Viewer
	XP_021587554	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000010315.3
GenBank Protein	KAG3264221	(Get FASTA)	NCBI Sequence Viewer
	KAG3264222	(Get FASTA)	NCBI Sequence Viewer
	KAG3264223	(Get FASTA)	NCBI Sequence Viewer
	KAG3264224	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005333713 ⟸ XM_005333656

- Peptide Label:

isoform X1

- Sequence:

show sequence

MVSPPPGAAAVARARLHVGPAPRPLMGSQGRSGTPGNSGPGEGEGGETRELQEARVVRGKRRKG
KGKAGAGQGGRGSGAEGKPGLQQAQEAAGSWVEAEAGAGPGRDSEGGGSVEEGAGSIEKGDEGS
TGAGKEAQGRLDGKEEERRGRTGRREDARPGKAQGQDGQAWGGIAGTGAAMAAAAEEEAAAREP
AARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRIARASLNSGFTR
LGTDLMSNVPVKERVKVSQNWRLGRCREGILLKWRCSQMPWMQLEDDSLYISQANFILAYKFRP
DGASLNRRPLGVFAGHDEDVCHFVLANSHIISAGGDGKIGVHKIHSTFTVKYSAHEQEVNCVDC
KGGIIVSGSRDRTAKVWPLASGRLGQCLHTIQTEDRVWSIAISPLLSSFVTGTACCGHFSPLRI
WDLNSGQLMTHLGSDFPPGAGVLDVMYESPSTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDS
TLYCLQTDGNHLLATGSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRFTTKHLYAALSY
NLHVLDFQNP

hide sequence

RefSeq Acc Id:

XP_021587554 ⟸ XM_021731879

- Peptide Label:

isoform X2

- Sequence:

show sequence

MSNVPVKERVKVSQNWRLGRCREGILLKWRCSQMPWMQLEDDSLYISQANFILAYKFRPDGASL
NRRPLGVFAGHDEDVCHFVLANSHIISAGGDGKIGVHKIHSTFTVKYSAHEQEVNCVDCKGGII
VSGSRDRTAKVWPLASGRLGQCLHTIQTEDRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNS
GQLMTHLGSDFPPGAGVLDVMYESPSTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDSTLYCL
QTDGNHLLATGSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRFTTKHLYAALSYNLHVL
DFQNP

hide sequence

Ensembl Acc Id:

ENSSTOP00000010315 ⟸ ENSSTOT00000011494

Protein Domains

F-box

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000011495	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000011494.3	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1280.50	UniProtKB/TrEMBL
	2.130.10.10	UniProtKB/TrEMBL
InterPro	F-box-like_dom_sf	UniProtKB/TrEMBL
	F-box_dom	UniProtKB/TrEMBL
	SCF_F-box/WD-repeat	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
NCBI Gene	Fbxw4	ENTREZGENE
PANTHER	DACTYLIN	UniProtKB/TrEMBL
	F-BOX/WD REPEAT-CONTAINING PROTEIN 4	UniProtKB/TrEMBL
Pfam	F-box-like	UniProtKB/TrEMBL
	WD40	UniProtKB/TrEMBL
PROSITE	FBOX	UniProtKB/TrEMBL
	WD_REPEATS_2	UniProtKB/TrEMBL
SMART	WD40	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50978	UniProtKB/TrEMBL
	SSF81383	UniProtKB/TrEMBL
UniProt	I3MHF7_ICTTR	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar