Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Fbxw4 (F-box and WD-40 domain protein 4) Mus musculus
Analyze
Symbol: Fbxw4
Name: F-box and WD-40 domain protein 4
Description: Involved in cartilage development; embryonic digit morphogenesis; and positive regulation of mesenchymal cell proliferation. Predicted to localize to the SCF ubiquitin ligase complex. Human ortholog(s) of this gene implicated in split hand-foot malformation 3. Is expressed in brain; diencephalon roof plate; midbrain ventricular layer; and midbrain-hindbrain junction. Orthologous to human FBXW4 (F-box and WD repeat domain containing 4); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Dac; dactylaplasia; dactylin; dactylyn; F-box and WD-40 domain-containing protein 4; F-box protein Fbw4; F-box/WD repeat-containing protein 4; Fbw4; hagoromo; SHFM3; SHSF3
Orthologs:
Homo sapiens (human) : FBXW4 (F-box and WD repeat domain containing 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fbxw4 (F-box and WD repeat domain containing 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxw4 (F-box and WD repeat domain containing 4)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXW4 (F-box and WD repeat domain containing 4)
Canis lupus familiaris (dog) : FBXW4 (F-box and WD repeat domain containing 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxw4 (F-box and WD repeat domain containing 4)
Sus scrofa (pig) : FBXW4 (F-box and WD repeat domain containing 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1945,578,254 - 45,660,312 (-)Ensembl
GRCm381945,578,254 - 45,660,520 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371945,652,747 - 45,734,683 (-)NCBIGRCm37mm9NCBIm37
MGSCv361945,631,568 - 45,713,504 (-)NCBImm8
Celera1946,345,905 - 46,428,364 (-)NCBICelera
Cytogenetic Map19 C3NCBI
cM Map1938.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fbxw4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1315183
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.