Kpnb1 (karyopherin subunit beta 1) - Rat Genome Database

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Gene: Kpnb1 (karyopherin subunit beta 1) Ictidomys tridecemlineatus
Analyze
Symbol: Kpnb1
Name: karyopherin subunit beta 1
RGD ID: 12472582
Description: ENCODES a protein that exhibits kinesin binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN protein import into nucleus (ortholog); ribosomal protein import into nucleus (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); human immunodeficiency virus infectious disease (ortholog); ovarian carcinoma (ortholog); FOUND IN cytoplasm (ortholog); nuclear pore (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: importin subunit beta-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560223,439,655 - 23,471,619 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649013,603,498 - 13,635,682 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649013,603,520 - 13,635,567 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kpnb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560223,439,655 - 23,471,619 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649013,603,498 - 13,635,682 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649013,603,520 - 13,635,567 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KPNB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381747,649,919 - 47,685,505 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1747,649,476 - 47,685,505 (+)EnsemblGRCh38hg38GRCh38
GRCh371745,727,285 - 45,762,871 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361743,082,274 - 43,116,003 (+)NCBINCBI36Build 36hg18NCBI36
Build 341743,082,273 - 43,116,003NCBI
Celera1742,179,952 - 42,213,682 (+)NCBICelera
Cytogenetic Map17q21.32NCBI
HuRef1741,096,264 - 41,130,080 (+)NCBIHuRef
CHM1_11745,792,168 - 45,825,949 (+)NCBICHM1_1
T2T-CHM13v2.01748,511,703 - 48,547,295 (+)NCBIT2T-CHM13v2.0
Kpnb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391197,050,536 - 97,078,718 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1197,050,540 - 97,078,707 (-)EnsemblGRCm39 Ensembl
GRCm381197,159,710 - 97,187,892 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1197,159,714 - 97,187,881 (-)EnsemblGRCm38mm10GRCm38
MGSCv371197,021,024 - 97,049,206 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361196,975,800 - 97,003,982 (-)NCBIMGSCv36mm8
Celera11106,812,630 - 106,840,820 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1160.95NCBI
Kpnb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81082,642,082 - 82,670,856 (-)NCBIGRCr8
mRatBN7.21082,145,662 - 82,174,437 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1082,145,420 - 82,174,605 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1087,094,110 - 87,122,899 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01086,592,172 - 86,620,969 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01081,984,776 - 82,013,559 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01085,096,517 - 85,124,641 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1085,093,841 - 85,124,644 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01084,886,484 - 84,914,805 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41085,882,382 - 85,910,805 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11085,896,751 - 85,925,175 (-)NCBI
Celera1080,906,145 - 80,931,812 (-)NCBICelera
Cytogenetic Map10q31NCBI
Kpnb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545113,365,476 - 13,398,491 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545113,365,881 - 13,398,491 (-)NCBIChiLan1.0ChiLan1.0
KPNB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21917,417,441 - 17,453,002 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11719,382,919 - 19,418,880 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0179,852,424 - 9,887,111 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11710,035,738 - 10,068,401 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1710,035,732 - 10,068,913 (-)Ensemblpanpan1.1panPan2
KPNB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1924,004,191 - 24,031,370 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl924,003,968 - 24,028,531 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha923,470,348 - 23,497,535 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0924,796,218 - 24,823,411 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl924,795,998 - 24,821,055 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1923,566,722 - 23,593,892 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0923,827,962 - 23,855,184 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0923,954,771 - 23,981,965 (+)NCBIUU_Cfam_GSD_1.0
KPNB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1223,916,164 - 23,944,588 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11223,915,783 - 23,945,407 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21223,785,821 - 23,813,399 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KPNB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11668,047,473 - 68,083,290 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1668,047,491 - 68,084,778 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607739,091,438 - 39,128,535 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kpnb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247954,371,749 - 4,403,217 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247954,372,014 - 4,403,061 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000007919   ⟹   ENSSTOP00000007087
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493649013,603,498 - 13,635,682 (-)Ensembl
Ensembl Acc Id: ENSSTOT00000039331   ⟹   ENSSTOP00000025697
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493649013,603,498 - 13,635,682 (-)Ensembl
RefSeq Acc Id: XM_005321746   ⟹   XP_005321803
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560223,439,655 - 23,471,619 (+)NCBI
SpeTri2.0NW_00493649013,603,520 - 13,635,567 (-)NCBI
Sequence:
RefSeq Acc Id: XR_005726345
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560223,439,699 - 23,471,619 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005321803 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000007087.3
  ENSSTOP00000025697.1
GenBank Protein KAG3269141 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005321803   ⟸   XM_005321746
- UniProtKB: A0A287CWL9 (UniProtKB/TrEMBL),   I3MAN7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000007087   ⟸   ENSSTOT00000007919
Ensembl Acc Id: ENSSTOP00000025697   ⟸   ENSSTOT00000039331
Protein Domains
Importin N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000007896 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000007919.3 UniProtKB/TrEMBL
  ENSSTOT00000039331.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Armadillo UniProtKB/TrEMBL
  HEAT_type_2 UniProtKB/TrEMBL
  Importin-beta_N UniProtKB/TrEMBL
  Importin_beta UniProtKB/TrEMBL
NCBI Gene Kpnb1 ENTREZGENE
PANTHER IMPORTIN SUBUNIT BETA-1 UniProtKB/TrEMBL
  PTHR10527 UniProtKB/TrEMBL
Pfam HEAT_EZ UniProtKB/TrEMBL
  IBN_N UniProtKB/TrEMBL
PROSITE HEAT_REPEAT UniProtKB/TrEMBL
  IMPORTIN_B_NT UniProtKB/TrEMBL
SMART ARM UniProtKB/TrEMBL
  IBN_N UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A287CWL9 ENTREZGENE, UniProtKB/TrEMBL
  I3MAN7 ENTREZGENE, UniProtKB/TrEMBL