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Gene: Fbxl4 (F-box and leucine rich repeat protein 4) Ictidomys tridecemlineatus

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Symbol:

Fbxl4

Name:

F-box and leucine rich repeat protein 4

RGD ID:

12462124

Description:

ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN autophagy of mitochondrion (inferred); negative regulation of mitophagy (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); ASSOCIATED WITH genetic disease (ortholog); Leigh disease (ortholog); mitochondrial DNA depletion syndrome (ortholog); FOUND IN mitochondrion (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

F-box/LRR-repeat protein 4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	92,074,873 - 92,153,958 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936651	530,197 - 609,417 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936651	530,296 - 609,443 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Fbxl4	Squirrel	genetic disease		ISO	FBXL4 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:23993193 more ...
Fbxl4	Squirrel	Leigh disease		ISO	FBXL4 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Leigh syndrome	ClinVar	PMID:23993193 more ...
Fbxl4	Squirrel	mitochondrial DNA depletion syndrome		ISO	FBXL4 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome	ClinVar	PMID:23993193 more ...
Fbxl4	Squirrel	mitochondrial DNA depletion syndrome 13		ISO	FBXL4 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:16199547 more ...
Fbxl4	Squirrel	mitochondrial encephalomyopathy		ISO	FBXL4 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Mitochondrial encephalomyopathy	ClinVar	PMID:23993194 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Fbxl4	Squirrel	mitochondrial DNA depletion syndrome 13		ISO	FBXL4 (Homo sapiens)	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Fbxl4	Squirrel	autophagy of mitochondrion	acts_upstream_of_or_within	IEA	UniProtKB:Q8BH70 more ...	150520179		Ensembl	GO_REF:0000107
Fbxl4	Squirrel	negative regulation of mitophagy	involved_in	IEA	UniProtKB:Q9UKA2 and ensembl:ENSP00000358247	150520179		Ensembl	GO_REF:0000107
Fbxl4	Squirrel	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	involved_in	IEA	PANTHER:PTN000565379	150520179		TreeGrafter	GO_REF:0000118

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Fbxl4	Squirrel	mitochondrial intermembrane space	located_in	IEA	UniProtKB:Q9UKA2 and ensembl:ENSP00000358247	150520179		Ensembl	GO_REF:0000107
Fbxl4	Squirrel	mitochondrial outer membrane	is_active_in	IEA	UniProtKB:Q9UKA2 and ensembl:ENSP00000358247	150520179		Ensembl	GO_REF:0000107
Fbxl4	Squirrel	mitochondrion	located_in	ISO	FBXL4 (Homo sapiens)	9068941	PMID:34800366	FlyBase	PMID:34800366
Fbxl4	Squirrel	nuclear speck	located_in	IEA	UniProtKB:Q9UKA2 and ensembl:ENSP00000358247	150520179		Ensembl	GO_REF:0000107
Fbxl4	Squirrel	SCF ubiquitin ligase complex	part_of	IEA	PANTHER:PTN000565379	150520179		TreeGrafter	GO_REF:0000118

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Fbxl4	Squirrel	protein binding	enables	ISO	UniProtKB:O14773 and UniProtKB:P50570-2	9068941	PMID:32814053	IntAct	PMID:32814053
Fbxl4	Squirrel	ubiquitin-like ligase-substrate adaptor activity	enables	IEA	UniProtKB:Q9UKA2 and ensembl:ENSP00000358247	150520179		Ensembl	GO_REF:0000107

PMID:22301074	PMID:30032202

Fbxl4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	92,074,873 - 92,153,958 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936651	530,197 - 609,417 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936651	530,296 - 609,443 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FBXL4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	98,868,535 - 98,947,946 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	98,868,535 - 98,948,006 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	99,316,411 - 99,395,822 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	99,428,322 - 99,502,570 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	99,428,321 - 99,502,570	NCBI
Celera	6	99,965,788 - 100,040,008 (-)	NCBI		Celera
Cytogenetic Map	6	q16.1-q16.2	NCBI
HuRef	6	96,760,379 - 96,835,106 (-)	NCBI		HuRef
CHM1_1	6	99,584,542 - 99,658,828 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	100,042,904 - 100,122,314 (-)	NCBI		T2T-CHM13v2.0

Fbxl4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	22,357,526 - 22,434,091 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	22,357,543 - 22,434,091 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	22,357,526 - 22,434,091 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	22,357,543 - 22,434,091 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	22,284,712 - 22,361,193 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	22,448,400 - 22,524,881 (+)	NCBI		MGSCv36	mm8
Celera	4	22,111,884 - 22,188,205 (+)	NCBI		Celera
Cytogenetic Map	4	A3	NCBI
cM Map	4	9.69	NCBI

Fbxl4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	40,752,513 - 40,826,154 (+)	NCBI		GRCr8
mRatBN7.2	5	35,955,801 - 36,029,446 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	35,955,812 - 36,029,443 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	38,081,930 - 38,155,709 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	39,674,526 - 39,748,301 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	39,614,187 - 39,687,968 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	36,555,061 - 36,628,920 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	36,555,109 - 36,629,689 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	41,196,912 - 41,270,903 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	37,156,876 - 37,230,228 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	37,157,055 - 37,230,404 (+)	NCBI
Celera	5	34,966,228 - 35,039,999 (+)	NCBI		Celera
Cytogenetic Map	5	q21	NCBI

Fbxl4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	24,757,445 - 24,814,643 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955411	24,757,445 - 24,814,642 (-)	NCBI	ChiLan1.0	ChiLan1.0

FBXL4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	118,922,871 - 118,996,545 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	116,801,917 - 116,877,758 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	96,717,103 - 96,790,932 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	100,599,381 - 100,661,249 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	100,599,390 - 100,661,249 (-)	Ensembl	panpan1.1		panPan2

FBXL4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	57,139,183 - 57,211,157 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	57,139,491 - 57,211,137 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	56,897,651 - 56,975,979 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	57,960,791 - 58,039,209 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	57,960,791 - 58,039,197 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	57,320,719 - 57,399,019 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	57,164,097 - 57,242,411 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	57,408,790 - 57,487,147 (-)	NCBI		UU_Cfam_GSD_1.0

FBXL4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	65,872,123 - 65,935,703 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	65,872,119 - 65,936,442 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	74,422,380 - 74,485,593 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FBXL4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	74,916,756 - 74,993,959 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	74,916,869 - 74,997,462 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	47,249,024 - 47,326,291 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fbxl4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624810	6,185,748 - 6,239,481 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624810	6,172,807 - 6,238,045 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_005335875	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040283128	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040283129	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000002522 ⟹ ENSSTOP00000002255

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936651	530,197 - 609,417 (-)	Ensembl

Ensembl Acc Id:

ENSSTOT00000022973 ⟹ ENSSTOP00000015822

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936651	530,197 - 609,417 (-)	Ensembl

RefSeq Acc Id:

XM_005335875 ⟹ XP_005335932

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	92,074,874 - 92,153,958 (-)	NCBI
SpeTri2.0	NW_004936651	530,296 - 609,443 (-)	NCBI

Sequence:

show sequence

GGCCCCGCCCCGAGTCCCGCTCCTCCTCCAGCCCCGCCCCTCCCCGCGGCCTCCGTGTCTTCCTTCCGGGTCGCGCTGGGCCGGGCTTGCCGCGGTGGTGCCGCAGCGCGAGAGCCTGGGAGCGGCCT
CGCGCCCAGGCCTTCCCGCGCCTCCTGGTCGGGGGTGAAGCCCTCGGCGCGTGCCACTCCCGGACCCTGCAGGGTAAAATAATGTCACATTTTAGCATTTGTACCTGAAAGCAGCAAGCAGATTTCAG
GCCACATGGATGAGTGCCAGCTTCTACATTTCCCTTGTGTATCCTGTGACCATTCTATCTGGGAACATCCTTCAAAGAGTTCTTGCATCTTACTGAGGACACCTGACCTTTTGAAGCTTCATAATTCA
CATCTAGATGTCACCGGTCTTTCCCATGTTAACAGTTTTGACTATGTTTTATTATATGTGCCTTCGGCGCCGAGCCAGGACAGCTACAAGAGGAGAAATGATGAACAGCCATAGAACTATAGAATCAA
ACAGCCGGACTTCCCCTCTCAATGCAGAGGTGGTCCAATATGCCAAAGAAGTAGTGGATTTCAGTTCCCATTATGGAAGCGAGAATAGTATGTCCTATACCATGTGGAATTTGGCAGGTGTACCAAAT
GTATTCCCAAGTTCTGGTGACTTTACTCAGACTGCTGTGTTTCGAACTTATGGAACGTGGTGGGATCAGTGTCCTAGTGCTTCCTTGCCATTCAAGAGGACACCGCCTAATTTTCAGAGCCAAGACTA
TGTGGAACTTACGTTTGAACAACAGGTATATCCTACAGCTGTTCATGTTCTGGAAACCTATCATCCTGGAGCAGTCATCAGAATTTTGGCTTGTTCTGCAAATCCATATTCTCCAAGTCCCCCAGCTG
AAGTAAGATGGGAGATTCTTTGGTCAGAGAGACCTACGAAGGTGAATGCTTCCCAAGCTCGTCAGTTTAAACCTTGTATTAAGCAGATAAATTTTCCCACAAATCTTATTCGACTGGAAATAAATAGT
TCTCTTCTGGATTATTACACTGAATTAGATGCAGTTGTGCTACATGGTATGAAGGACAAGCCAGTGCTTTCTCTTAAGACTTCACTTATTGACATGAATGATCTAGAAGATGATGACTATGAAGAAGA
GGATGGTTGTGGAATGGACAATCTTAACAAAAAATTTAGCAGTACTGCCCTCAAGGAAGGGCCAAATAATGGATATTTTGATAAATTACCATATGAGCTTATTCAACTGATTCTGAATCATCTTACAC
TACCAGACCTGTGTAGATTAGCACAAACTTGCAAACTGCTACACCAGCATTGCTGTGATCCTCTACAGTATATCCACCTCAATCTGCAGCCATACTGGGCAAAGCTAAATGACACTTCTCTGGAGTTC
CTGCAGGCTCGATGTACCCTTGTCCAGTGGCTCAATTTATCTTGGACTGGCAATAGAGGCTTCATCTCTGTTGCAGGATTTAGCAGGTTTCTGAAGGTTTGTGGATCTGAATTAGTACGCCTTGAATT
ATCTTGCAGCCATTTCCTTAATGAAACTTGCTTGGAGGTTATTTCTGAGATGTGTCCAGATCTACAAGATTTAAATCTCTCATCCTGTGATAAATTACCACCTCAAGCATTCAACCACATTGCCAAGT
TATGCAGCCTTAAACGACTTGTTCTCTATCGAACAAAAGTAGAGCAAACAGCACTGCTCAGCATTTTGAACTTCTGTTCAGAGCTTCAGCACCTCAGTTTGGGCAGTTGTGTAATGATTGAAGACTAT
GATGTGATAGCTAGCATGATAGGAGCCAAGTGTAAAAAGCTCCGCACCCTGGATCTATGGAGATGTAAGAATATTACTGAGAATGGAATAGCGGAACTGGCTTCTGGATGTCCACTTCTGGAGGAACT
TGACCTTGGCTGGTGTCCTACTCTGCAGAGCAGTACCGGGTGCTTCGCCAGATTGGCACGCCAGCTCCCAAACTTGCAAAAACTATTTCTTACAGCTAATAGATCTGTGTGTGACACAGATATAGAAG
AACTTGCATGTAATTGTATCAGATTACGGCAACTGGACATATTAGGAACAAGAATGGTAAGTCCAGCATCCTTAAGAAAACTCCTGGAATCTTGTAAAGATCTTTCCTTACTTGATGTATCCTTCTGT
TCACAGATTGATAACAGAGCTGTATTAGAACTGAATGCAACCTTTCCAAAAGTGTTCATAAAAAAGAGCTTTACTCAGTGACTTAATATATATTATGTCACTAAAAGTTGATATGCTTTGTAAGGATT
TTATTTGGAGGTGGTTTTGTTGTATCTTTTGTTTTTATAATGGTGAGGATTAAGACATTTGTGGATTTTAAAGAAAAATATGAAATTTCCCATTGAATCAAGTAAAAAATGTGAAGAAATGTTCTCAC
AAAATACTGTAAGCCATTTTCATCAAGAATATGTTAGTCACTGATATTATTTTTACTTTGTGTTAAAGTGGAATTATGTTTTAATCAATAATTGTGTTAATAAAAGAATAATATGAAAACATTTTAAC
TTATTTTTAAAGGGATGCTTTAAGCATTAAAGTATCATGATATTTATGCAAAAATAAAGTTTTTTTCACACTTCAT

hide sequence

RefSeq Acc Id:

XM_040283128 ⟹ XP_040139062

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	92,074,873 - 92,153,955 (-)	NCBI

RefSeq Acc Id:

XM_040283129 ⟹ XP_040139063

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	92,075,268 - 92,153,955 (-)	NCBI


Protein RefSeqs	XP_005335932	(Get FASTA)	NCBI Sequence Viewer
	XP_040139062	(Get FASTA)	NCBI Sequence Viewer
	XP_040139063	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000002255.3
	ENSSTOP00000015822.2
GenBank Protein	KAG3289969	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005335932 ⟸ XM_005335875
- Peptide Label:	isoform X1
- UniProtKB:	I3M0K9 (UniProtKB/TrEMBL), I3MUM7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSPVFPMLTVLTMFYYMCLRRRARTATRGEMMNSHRTIESNSRTSPLNAEVVQYAKEVVDFSSHYGSENSMSYTMWNLAGVPNVFPSSGDFTQTAVFRTYGTWWDQCPSASLPFKRTPPNFQSQDYVE LTFEQQVYPTAVHVLETYHPGAVIRILACSANPYSPSPPAEVRWEILWSERPTKVNASQARQFKPCIKQINFPTNLIRLEINSSLLDYYTELDAVVLHGMKDKPVLSLKTSLIDMNDLEDDDYEEEDG CGMDNLNKKFSSTALKEGPNNGYFDKLPYELIQLILNHLTLPDLCRLAQTCKLLHQHCCDPLQYIHLNLQPYWAKLNDTSLEFLQARCTLVQWLNLSWTGNRGFISVAGFSRFLKVCGSELVRLELSC SHFLNETCLEVISEMCPDLQDLNLSSCDKLPPQAFNHIAKLCSLKRLVLYRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLEELDL GWCPTLQSSTGCFARLARQLPNLQKLFLTANRSVCDTDIEELACNCIRLRQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLELNATFPKVFIKKSFTQ hide sequence

RefSeq Acc Id:	XP_040139062 ⟸ XM_040283128
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_040139063 ⟸ XM_040283129
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSSTOP00000002255 ⟸ ENSSTOT00000002522

Ensembl Acc Id:

ENSSTOP00000015822 ⟸ ENSSTOT00000022973

Protein Domains

F-box

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000002526	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000002522.3	UniProtKB/TrEMBL
	ENSSTOT00000022973.2	UniProtKB/TrEMBL
Gene3D-CATH	3.80.10.10	UniProtKB/TrEMBL
InterPro	F-box-like_dom_sf	UniProtKB/TrEMBL
	F-box_dom	UniProtKB/TrEMBL
	Leu-rich_rpt_Cys-con_subtyp	UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/TrEMBL
NCBI Gene	Fbxl4	ENTREZGENE
PANTHER	F-BOX/LRR-REPEAT PROTEIN 4	UniProtKB/TrEMBL
	UNCHARACTERIZED	UniProtKB/TrEMBL
Pfam	F-box-like	UniProtKB/TrEMBL
PROSITE	FBOX	UniProtKB/TrEMBL
SMART	LRR_CC	UniProtKB/TrEMBL
Superfamily-SCOP	RNI-like	UniProtKB/TrEMBL
	SSF81383	UniProtKB/TrEMBL
UniProt	I3M0K9	ENTREZGENE, UniProtKB/TrEMBL
	I3MUM7	ENTREZGENE
UniProt Secondary	I3MUM7	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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