Gng12 (G protein subunit gamma 12) - Rat Genome Database

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Gene: Gng12 (G protein subunit gamma 12) Ictidomys tridecemlineatus
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Symbol: Gng12
Name: G protein subunit gamma 12
RGD ID: 12461872
Description: ENCODES a protein that exhibits phosphate ion binding (ortholog); INVOLVED IN cerebral cortex development (ortholog); response to lipopolysaccharide (ortholog); PARTICIPATES IN adenosine signaling pathway; dopamine signaling pathway via D1 family of receptors; follicle-stimulating hormone signaling pathway; ASSOCIATED WITH intellectual disability (ortholog); FOUND IN actin filament (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505880,506,244 - 80,674,824 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365913,977,507 - 3,980,065 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365913,860,668 - 3,983,305 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gng12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505880,506,244 - 80,674,824 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365913,977,507 - 3,980,065 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365913,860,668 - 3,983,305 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNG12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38167,701,475 - 67,833,467 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl167,701,475 - 67,833,467 (-)EnsemblGRCh38hg38GRCh38
GRCh37168,167,158 - 68,299,150 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36167,939,737 - 68,071,730 (-)NCBINCBI36Build 36hg18NCBI36
Build 34167,879,242 - 68,011,129NCBI
Celera166,458,012 - 66,589,844 (-)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef166,277,405 - 66,409,293 (-)NCBIHuRef
CHM1_1168,281,656 - 68,413,579 (-)NCBICHM1_1
T2T-CHM13v2.0167,578,994 - 67,710,912 (-)NCBIT2T-CHM13v2.0
Gng12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39666,873,381 - 66,998,345 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl666,873,381 - 66,998,334 (+)EnsemblGRCm39 Ensembl
GRCm38666,896,397 - 67,021,361 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl666,896,397 - 67,021,350 (+)EnsemblGRCm38mm10GRCm38
MGSCv37666,846,391 - 66,971,355 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36666,826,034 - 66,950,872 (+)NCBIMGSCv36mm8
Celera669,009,110 - 69,142,819 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map630.68NCBI
Gng12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8497,340,830 - 97,464,422 (+)NCBIGRCr8
mRatBN7.2496,011,118 - 96,134,767 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl496,010,952 - 96,134,712 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4101,285,782 - 101,380,771 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0497,060,751 - 97,155,744 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0495,485,792 - 95,580,682 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0497,634,925 - 97,763,478 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl497,657,671 - 97,760,102 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04162,420,268 - 162,549,350 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4496,622,363 - 96,624,479 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1496,866,867 - 96,868,580 (+)NCBI
Celera490,733,078 - 90,828,214 (+)NCBICelera
Cytogenetic Map4q31NCBI
Gng12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542323,634,402 - 23,644,600 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542323,576,515 - 23,644,600 (+)NCBIChiLan1.0ChiLan1.0
GNG12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21159,037,990 - 159,167,844 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11158,197,602 - 158,327,585 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0166,941,315 - 67,071,442 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1168,897,289 - 69,025,742 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl168,901,264 - 68,903,487 (-)Ensemblpanpan1.1panPan2
GNG12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1677,316,649 - 77,378,356 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl677,338,685 - 77,374,937 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha679,907,731 - 79,987,868 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0677,972,445 - 77,978,233 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1677,452,925 - 77,558,595 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0677,346,730 - 77,427,239 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0677,832,739 - 77,913,898 (+)NCBIUU_Cfam_GSD_1.0
GNG12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6144,782,503 - 144,918,549 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16144,782,478 - 144,918,556 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28115,141,133 - 115,141,412 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GNG12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12065,280,816 - 65,409,685 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2065,403,471 - 65,405,699 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603352,202,558 - 52,331,733 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gng12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474227,700,538 - 27,718,555 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474227,652,114 - 27,721,668 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000004490   ⟹   ENSSTOP00000004030
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365913,977,507 - 3,980,065 (+)Ensembl
RefSeq Acc Id: XM_005332361   ⟹   XP_005332418
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505880,506,244 - 80,628,888 (-)NCBI
SpeTri2.0NW_0049365913,860,668 - 3,983,305 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040288830   ⟹   XP_040144764
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505880,506,244 - 80,587,740 (-)NCBI
RefSeq Acc Id: XM_040288831   ⟹   XP_040144765
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505880,506,244 - 80,674,824 (-)NCBI
RefSeq Acc Id: XM_040288832   ⟹   XP_040144766
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505880,506,244 - 80,629,227 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005332418 (Get FASTA)   NCBI Sequence Viewer  
  XP_040144764 (Get FASTA)   NCBI Sequence Viewer  
  XP_040144765 (Get FASTA)   NCBI Sequence Viewer  
  XP_040144766 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000004030.1
GenBank Protein KAG3283359 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005332418   ⟸   XM_005332361
- UniProtKB: I3M4C6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040144765   ⟸   XM_040288831
- UniProtKB: I3M4C6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040144766   ⟸   XM_040288832
- UniProtKB: I3M4C6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040144764   ⟸   XM_040288830
- UniProtKB: I3M4C6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000004030   ⟸   ENSSTOT00000004490
Protein Domains
G protein gamma


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004502 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004490.2 UniProtKB/TrEMBL
Gene3D-CATH 4.10.260.10 UniProtKB/TrEMBL
InterPro G-protein_gamma-like_dom UniProtKB/TrEMBL
  GGL_sf UniProtKB/TrEMBL
  Gprotein-gamma UniProtKB/TrEMBL
NCBI Gene Gng12 ENTREZGENE
PANTHER GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-12 UniProtKB/TrEMBL
  PTHR13809 UniProtKB/TrEMBL
Pfam G-gamma UniProtKB/TrEMBL
PRINTS GPROTEING UniProtKB/TrEMBL
PROSITE G_PROTEIN_GAMMA UniProtKB/TrEMBL
SMART G_gamma UniProtKB/TrEMBL
  GGL UniProtKB/TrEMBL
Superfamily-SCOP SSF48670 UniProtKB/TrEMBL
UniProt I3M4C6 ENTREZGENE, UniProtKB/TrEMBL