Mtx2 (metaxin 2) - Rat Genome Database

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Gene: Mtx2 (metaxin 2) Ictidomys tridecemlineatus
Analyze
Symbol: Mtx2
Name: metaxin 2
RGD ID: 12458893
Description: INVOLVED IN mitochondrial transport (inferred); mitochondrion organization (inferred); protein transport (inferred); PARTICIPATES IN beta-barrel pathway of mitochondrial protein import; ASSOCIATED WITH Mandibuloacral Dysplasia Progeroid Syndrome (ortholog); megacolon (ortholog); split hand-foot malformation 5 (ortholog); FOUND IN SAM complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: metaxin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303137,189,131 - 137,245,686 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365095,742,987 - 5,799,652 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365095,743,004 - 5,799,326 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mtx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303137,189,131 - 137,245,686 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365095,742,987 - 5,799,652 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365095,743,004 - 5,799,326 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382176,269,442 - 176,338,025 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2176,269,395 - 176,338,025 (+)EnsemblGRCh38hg38GRCh38
GRCh372177,134,170 - 177,202,753 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362176,842,383 - 176,910,999 (+)NCBINCBI36Build 36hg18NCBI36
Build 342176,959,643 - 177,028,258NCBI
Celera2170,743,298 - 170,811,933 (+)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2169,011,032 - 169,079,657 (+)NCBIHuRef
CHM1_12177,139,996 - 177,208,619 (+)NCBICHM1_1
T2T-CHM13v2.02176,757,567 - 176,826,151 (+)NCBIT2T-CHM13v2.0
Mtx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39274,656,156 - 74,707,092 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl274,656,147 - 74,708,775 (+)EnsemblGRCm39 Ensembl
GRCm38274,825,812 - 74,876,748 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl274,825,803 - 74,878,431 (+)EnsemblGRCm38mm10GRCm38
MGSCv37274,663,869 - 74,714,805 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36274,626,690 - 74,679,270 (+)NCBIMGSCv36mm8
Celera276,496,168 - 76,547,115 (+)NCBICelera
Cytogenetic Map2C3NCBI
cM Map244.13NCBI
Mtx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8380,137,556 - 80,199,547 (+)NCBIGRCr8
mRatBN7.2359,730,206 - 59,792,202 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl359,730,197 - 59,792,201 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx363,117,225 - 63,179,188 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0371,700,873 - 71,762,834 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0369,465,936 - 69,527,955 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0361,756,109 - 61,818,999 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl361,756,148 - 61,818,998 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0368,216,558 - 68,279,582 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4357,460,900 - 57,523,379 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1357,357,271 - 57,419,750 (+)NCBI
Celera359,247,074 - 59,309,016 (+)NCBICelera
Cytogenetic Map3q23NCBI
Mtx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540320,359,527 - 20,412,742 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540320,359,524 - 20,412,473 (-)NCBIChiLan1.0ChiLan1.0
MTX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21378,938,063 - 79,001,361 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B78,953,051 - 79,016,335 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B63,550,345 - 63,613,626 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B181,258,622 - 181,321,912 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B181,258,622 - 181,321,912 (+)Ensemblpanpan1.1panPan2
MTX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13620,067,577 - 20,134,303 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3620,067,424 - 20,390,053 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3620,088,010 - 20,143,656 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03620,220,108 - 20,276,530 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3620,209,088 - 20,276,367 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13620,293,892 - 20,349,526 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03620,294,474 - 20,350,096 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03620,406,105 - 20,461,748 (+)NCBIUU_Cfam_GSD_1.0
MTX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1582,061,385 - 82,139,072 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11582,061,381 - 82,139,073 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21591,528,880 - 91,635,859 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MTX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11061,845,509 - 61,914,661 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1061,845,564 - 61,917,012 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040137,695,873 - 137,765,883 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mtx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478713,398,713 - 13,459,695 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478713,399,293 - 13,459,819 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000014688   ⟹   ENSSTOP00000013157
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365095,742,987 - 5,799,652 (+)Ensembl
RefSeq Acc Id: XM_005324635   ⟹   XP_005324692
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303137,189,131 - 137,245,686 (+)NCBI
SpeTri2.0NW_0049365095,743,004 - 5,799,326 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040294506   ⟹   XP_040150440
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303137,189,512 - 137,245,686 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005324692 (Get FASTA)   NCBI Sequence Viewer  
  XP_040150440 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000013157.3
GenBank Protein KAG3274762 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005324692   ⟸   XM_005324635
- Peptide Label: isoform X1
- UniProtKB: I3MND8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040150440   ⟸   XM_040294506
- Peptide Label: isoform X2
RefSeq Acc Id: ENSSTOP00000013157   ⟸   ENSSTOT00000014688
Protein Domains
Metaxin glutathione S-transferase   Mitochondrial outer membrane transport complex


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014688 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000014688.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1050.10 UniProtKB/TrEMBL
InterPro Glutathione-S-Trfase_C_sf UniProtKB/TrEMBL
  Glutathione_S-Trfase UniProtKB/TrEMBL
  Metaxin_GST UniProtKB/TrEMBL
  Sam37/metaxin_N UniProtKB/TrEMBL
NCBI Gene Mtx2 ENTREZGENE
PANTHER METAXIN RELATED UniProtKB/TrEMBL
  METAXIN-2 UniProtKB/TrEMBL
Pfam GST_C_6 UniProtKB/TrEMBL
  Tom37 UniProtKB/TrEMBL
Superfamily-SCOP SSF47616 UniProtKB/TrEMBL
UniProt I3MND8 ENTREZGENE, UniProtKB/TrEMBL