Cops7b (COP9 signalosome subunit 7B) - Rat Genome Database

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Gene: Cops7b (COP9 signalosome subunit 7B) Ictidomys tridecemlineatus
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Symbol: Cops7b
Name: COP9 signalosome subunit 7B
RGD ID: 12445580
Description: INVOLVED IN COP9 signalosome assembly (inferred); protein deneddylation (inferred); ASSOCIATED WITH Joubert syndrome 22 (ortholog); osteochondrodysplasia (ortholog); Perlman syndrome (ortholog); FOUND IN COP9 signalosome (inferred); cytoplasm (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: COP9 signalosome complex subunit 7b; COP9 signalosome subunit 7B, transcript variant X1; COP9 signalosome subunit 7B, transcript variant X2; COP9 signalosome subunit 7B, transcript variant X3; COP9 signalosome subunit 7B, transcript variant X4; COP9 signalosome subunit 7B, transcript variant X5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303185,753,572 - 185,780,853 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365255,156,785 - 5,182,012 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365255,159,157 - 5,186,142 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cops7b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303185,753,572 - 185,780,853 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365255,156,785 - 5,182,012 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365255,159,157 - 5,186,142 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COPS7B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382231,781,671 - 231,809,253 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2231,781,671 - 231,809,254 (+)EnsemblGRCh38hg38GRCh38
GRCh372232,646,381 - 232,673,963 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362232,359,406 - 232,381,678 (+)NCBINCBI36Build 36hg18NCBI36
Build 342232,476,666 - 232,498,939NCBI
Celera2226,427,678 - 226,449,946 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2224,495,756 - 224,515,928 (+)NCBIHuRef
CHM1_12232,656,979 - 232,679,248 (+)NCBICHM1_1
T2T-CHM13v2.02232,266,242 - 232,293,824 (+)NCBIT2T-CHM13v2.0
Cops7b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39186,510,363 - 86,534,550 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl186,510,626 - 86,537,097 (+)EnsemblGRCm39 Ensembl
GRCm38186,582,646 - 86,606,828 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl186,582,904 - 86,609,375 (+)EnsemblGRCm38mm10GRCm38
MGSCv37188,483,675 - 88,503,075 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36188,418,271 - 88,437,671 (+)NCBIMGSCv36mm8
Celera189,556,717 - 89,576,116 (+)NCBICelera
Cytogenetic Map1C5NCBI
cM Map143.97NCBI
Cops7b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8994,686,314 - 94,711,903 (+)NCBIGRCr8
mRatBN7.2987,238,132 - 87,263,967 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl987,238,375 - 87,263,967 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx995,654,909 - 95,680,466 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09100,783,098 - 100,808,674 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0999,166,666 - 99,192,255 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0993,607,199 - 93,633,064 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl993,607,477 - 93,633,064 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0993,335,116 - 93,361,000 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4985,353,285 - 85,378,872 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1985,541,787 - 85,560,985 (+)NCBI
Celera984,653,671 - 84,679,234 (+)NCBICelera
Cytogenetic Map9q35NCBI
Cops7b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554533,967,241 - 3,986,314 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554533,967,241 - 3,991,802 (-)NCBIChiLan1.0ChiLan1.0
COPS7B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213134,406,071 - 134,433,795 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B134,421,141 - 134,448,759 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B119,033,879 - 119,061,293 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B237,821,398 - 237,849,340 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B237,821,398 - 237,849,340 (+)Ensemblpanpan1.1panPan2
COPS7B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12543,637,170 - 43,663,218 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2543,637,335 - 43,661,654 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2544,130,643 - 44,156,556 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02543,893,737 - 43,919,891 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2543,893,973 - 43,919,891 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12543,821,166 - 43,847,074 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02543,664,546 - 43,690,798 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02543,819,902 - 43,845,831 (+)NCBIUU_Cfam_GSD_1.0
COPS7B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15132,427,173 - 132,450,689 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115132,427,023 - 132,451,199 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215146,193,566 - 146,201,261 (+)NCBISscrofa10.2Sscrofa10.2susScr3
COPS7B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110117,809,981 - 117,837,768 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10117,817,405 - 117,836,665 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604081,601,415 - 81,629,109 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cops7b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248434,780,374 - 4,801,692 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248434,776,689 - 4,801,692 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000027405   ⟹   ENSSTOP00000022182
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365255,156,785 - 5,182,012 (-)Ensembl
RefSeq Acc Id: XM_013359191   ⟹   XP_013214645
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303185,753,572 - 185,780,853 (+)NCBI
SpeTri2.0NW_0049365255,159,157 - 5,181,750 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013359192   ⟹   XP_013214646
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303185,753,573 - 185,780,853 (+)NCBI
SpeTri2.0NW_0049365255,159,157 - 5,186,142 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727091   ⟹   XP_021582766
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303185,758,185 - 185,780,853 (+)NCBI
SpeTri2.0NW_0049365255,159,157 - 5,180,158 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040268000   ⟹   XP_040123934
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303185,753,573 - 185,780,853 (+)NCBI
RefSeq Acc Id: XM_040268001   ⟹   XP_040123935
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303185,764,023 - 185,780,853 (+)NCBI
RefSeq Acc Id: XP_013214646   ⟸   XM_013359192
- Peptide Label: isoform X3
- UniProtKB: I3NCT5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013214645   ⟸   XM_013359191
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_021582766   ⟸   XM_021727091
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_040123934   ⟸   XM_040268000
- Peptide Label: isoform X3
- UniProtKB: I3NCT5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040123935   ⟸   XM_040268001
- Peptide Label: isoform X4
Ensembl Acc Id: ENSSTOP00000022182   ⟸   ENSSTOT00000027405
Protein Domains
PCI


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000022276 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000027405.2 UniProtKB/TrEMBL
InterPro COPS7/eIF3m UniProtKB/TrEMBL
  CSN7_helixI UniProtKB/TrEMBL
  PCI_dom UniProtKB/TrEMBL
NCBI Gene Cops7b ENTREZGENE
PANTHER PTHR15350 UniProtKB/TrEMBL
  PTHR15350:SF8 UniProtKB/TrEMBL
Pfam CSN7_HB_subdom UniProtKB/TrEMBL
  CSN7a_helixI UniProtKB/TrEMBL
  PCI UniProtKB/TrEMBL
PROSITE PCI UniProtKB/TrEMBL
SMART PINT UniProtKB/TrEMBL
UniProt I3NCT5 ENTREZGENE, UniProtKB/TrEMBL