Pex6 (peroxisomal biogenesis factor 6) - Rat Genome Database

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Gene: Pex6 (peroxisomal biogenesis factor 6) Ictidomys tridecemlineatus
Analyze
Symbol: Pex6
Name: peroxisomal biogenesis factor 6
RGD ID: 12441512
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); hydrolase activity (inferred); INVOLVED IN peroxisome organization (ortholog); ASSOCIATED WITH cerebellar ataxia (ortholog); Cognitive Dysfunction (ortholog); dystonia (ortholog); FOUND IN peroxisomal membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: peroxisomal biogenesis factor 6, transcript variant X1; peroxisomal biogenesis factor 6, transcript variant X2; peroxisomal biogenesis factor 6, transcript variant X3; peroxisomal biogenesis factor 6, transcript variant X4; peroxisomal biogenesis factor 6, transcript variant X5; peroxisomal biogenesis factor 6, transcript variant X6; peroxisome biogenesis factor 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494646,996,551 - 47,011,135 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647616,949,028 - 16,964,040 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647616,948,137 - 16,963,601 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pex6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494646,996,551 - 47,011,135 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647616,949,028 - 16,964,040 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647616,948,137 - 16,963,601 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PEX6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38642,963,865 - 42,979,181 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl642,963,865 - 42,979,181 (-)EnsemblGRCh38hg38GRCh38
GRCh37642,931,603 - 42,946,919 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,039,724 - 43,054,866 (-)NCBINCBI36Build 36hg18NCBI36
Build 34643,039,724 - 43,054,866NCBI
Celera644,483,862 - 44,499,224 (-)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef642,648,904 - 42,664,268 (-)NCBIHuRef
CHM1_1642,934,088 - 42,949,459 (-)NCBICHM1_1
T2T-CHM13v2.0642,793,003 - 42,808,304 (-)NCBIT2T-CHM13v2.0
Pex6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391747,022,402 - 47,036,469 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1747,022,389 - 47,036,467 (+)EnsemblGRCm39 Ensembl
GRCm381746,711,476 - 46,725,543 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,711,463 - 46,725,541 (+)EnsemblGRCm38mm10GRCm38
MGSCv371746,848,412 - 46,862,490 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361746,174,654 - 46,188,732 (+)NCBIMGSCv36mm8
Celera1750,147,145 - 50,161,227 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.9NCBI
Pex6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8921,755,747 - 21,767,939 (-)NCBIGRCr8
mRatBN7.2914,258,145 - 14,270,335 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,258,145 - 14,270,303 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx922,840,891 - 22,853,018 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0927,905,073 - 27,917,291 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0926,204,265 - 26,216,392 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0916,568,743 - 16,580,900 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl916,566,688 - 16,581,078 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0915,475,358 - 15,487,515 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4910,130,561 - 10,139,807 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1910,127,882 - 10,137,129 (-)NCBI
Celera912,006,590 - 12,018,743 (-)NCBICelera
Cytogenetic Map9q12NCBI
Pex6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554378,947,002 - 8,960,371 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554378,945,842 - 8,964,870 (-)NCBIChiLan1.0ChiLan1.0
PEX6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2557,462,366 - 57,479,149 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1653,332,570 - 53,354,666 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0642,554,509 - 42,570,701 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1643,849,802 - 43,865,618 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl643,850,129 - 43,865,355 (-)Ensemblpanpan1.1panPan2
PEX6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11211,503,184 - 11,514,977 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1211,503,240 - 11,514,929 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1211,530,201 - 11,541,972 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01211,984,383 - 11,996,155 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1211,984,400 - 11,996,144 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11211,512,805 - 11,524,577 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01211,597,069 - 11,608,845 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01211,691,136 - 11,702,909 (-)NCBIUU_Cfam_GSD_1.0
PEX6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl738,039,862 - 38,052,369 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1738,039,852 - 38,052,384 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2743,488,218 - 43,500,754 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PEX6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11729,180,427 - 29,198,747 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1729,180,460 - 29,200,398 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604443,010,475 - 43,039,028 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pex6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475416,510,795 - 16,527,859 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475416,510,980 - 16,534,695 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000009482   ⟹   ENSSTOP00000008504
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647616,949,028 - 16,964,040 (+)Ensembl
RefSeq Acc Id: XM_005318673   ⟹   XP_005318730
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494646,996,551 - 47,010,985 (-)NCBI
SpeTri2.0NW_00493647616,948,140 - 16,963,601 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021721893   ⟹   XP_021577568
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494646,997,986 - 47,010,985 (-)NCBI
SpeTri2.0NW_00493647616,948,140 - 16,962,129 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021721894   ⟹   XP_021577569
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494646,997,419 - 47,010,985 (-)NCBI
SpeTri2.0NW_00493647616,948,140 - 16,962,717 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040282689   ⟹   XP_040138623
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494646,998,545 - 47,010,985 (-)NCBI
RefSeq Acc Id: XM_040282690   ⟹   XP_040138624
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494646,998,832 - 47,011,134 (-)NCBI
RefSeq Acc Id: XR_001229567
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494646,999,671 - 47,011,135 (-)NCBI
SpeTri2.0NW_00493647616,948,137 - 16,960,531 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005318730   ⟸   XM_005318673
- Peptide Label: isoform X1
- UniProtKB: I3MDM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021577569   ⟸   XM_021721894
- Peptide Label: isoform X1
- UniProtKB: I3MDM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021577568   ⟸   XM_021721893
- Peptide Label: isoform X1
- UniProtKB: I3MDM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040138623   ⟸   XM_040282689
- Peptide Label: isoform X1
- UniProtKB: I3MDM8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040138624   ⟸   XM_040282690
- Peptide Label: isoform X2
Ensembl Acc Id: ENSSTOP00000008504   ⟸   ENSSTOT00000009482
Protein Domains
AAA+ ATPase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000009471 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000009482.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.60 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  AAA_ATPase_domain UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  ATPase_AAA_CS UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Pex6 ENTREZGENE
PANTHER AAA-FAMILY ATPASE UniProtKB/TrEMBL
  PEROXISOME ASSEMBLY FACTOR 2 UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
PROSITE AAA UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt I3MDM8 ENTREZGENE, UniProtKB/TrEMBL