CDH22 (cadherin 22) - Rat Genome Database

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Gene: CDH22 (cadherin 22) Canis lupus familiaris
Analyze
Symbol: CDH22
Name: cadherin 22
RGD ID: 12407556
Description: ENCODES a protein that exhibits cadherin binding (inferred); calcium ion binding (inferred); INVOLVED IN calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); focal epilepsy (ortholog); genetic disease (ortholog); FOUND IN adherens junction (inferred); catenin complex (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cadherin-22; cadherin-like 22
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,424,567 - 33,492,162 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,425,303 - 33,492,292 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2432,950,778 - 33,018,325 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02434,134,235 - 34,201,817 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2434,134,218 - 34,202,243 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,393,032 - 33,459,862 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,508,812 - 33,575,667 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02434,047,822 - 34,114,743 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CDH22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,424,567 - 33,492,162 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,425,303 - 33,492,292 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2432,950,778 - 33,018,325 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02434,134,235 - 34,201,817 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2434,134,218 - 34,202,243 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,393,032 - 33,459,862 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,508,812 - 33,575,667 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02434,047,822 - 34,114,743 (-)NCBIUU_Cfam_GSD_1.0
CDH22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382046,173,739 - 46,308,498 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2046,173,739 - 46,308,498 (-)EnsemblGRCh38hg38GRCh38
GRCh372044,802,378 - 44,937,137 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362044,235,783 - 44,313,741 (-)NCBINCBI36Build 36hg18NCBI36
Build 342044,235,782 - 44,313,741NCBI
Celera2041,513,832 - 41,591,744 (-)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2041,543,684 - 41,678,251 (-)NCBIHuRef
CHM1_12044,704,993 - 44,839,771 (-)NCBICHM1_1
T2T-CHM13v2.02047,909,792 - 48,044,527 (-)NCBIT2T-CHM13v2.0
Cdh22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392164,953,421 - 165,076,892 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2164,953,427 - 165,076,773 (-)EnsemblGRCm39 Ensembl
GRCm382165,111,501 - 165,234,924 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2165,111,507 - 165,234,853 (-)EnsemblGRCm38mm10GRCm38
MGSCv372164,937,007 - 165,060,237 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362164,802,714 - 164,925,924 (-)NCBIMGSCv36mm8
Celera2171,049,727 - 171,171,625 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.43NCBI
Cdh22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83174,264,869 - 174,389,940 (-)NCBIGRCr8
mRatBN7.23153,845,563 - 153,970,630 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,845,787 - 153,970,588 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,654,361 - 157,779,291 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03166,153,335 - 166,278,266 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,897,109 - 164,019,650 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,574,993 - 161,971,102 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,575,631 - 161,917,285 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,759,873 - 168,153,365 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43156,155,004 - 156,275,540 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16134,126,192 - 134,128,100 (+)NCBI
Celera3152,449,958 - 152,516,313 (-)NCBICelera
Cytogenetic Map3q42NCBI
Cdh22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544511,084,448 - 11,151,871 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544511,084,448 - 11,151,871 (+)NCBIChiLan1.0ChiLan1.0
CDH22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22151,913,754 - 52,048,497 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12051,906,860 - 52,041,601 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02042,511,264 - 42,645,662 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12043,596,777 - 43,674,105 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2043,597,548 - 43,674,070 (-)Ensemblpanpan1.1panPan2
Cdh22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,388,473 - 191,450,180 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365146,841,462 - 6,932,547 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365146,841,462 - 6,932,547 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDH22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1748,339,694 - 48,413,799 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11748,339,683 - 48,471,705 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21753,984,767 - 54,059,180 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDH22
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1217,573,244 - 17,709,470 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl217,631,664 - 17,708,309 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605066,209,735 - 66,344,425 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdh22
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247908,369,964 - 8,438,683 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247908,369,972 - 8,437,595 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CDH22
850 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 6
Low 5 5 17 6 6 6 6 6 8 10 6
Below cutoff 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000016196   ⟹   ENSCAFP00000014980
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2433,425,303 - 33,492,292 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845032925   ⟹   ENSCAFP00845025762
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2434,134,218 - 34,202,243 (-)Ensembl
RefSeq Acc Id: XM_038434007   ⟹   XP_038289935
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02434,134,235 - 34,201,817 (-)NCBI
RefSeq Acc Id: XM_038509166   ⟹   XP_038365094
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12433,393,032 - 33,459,862 (-)NCBI
RefSeq Acc Id: XM_038572499   ⟹   XP_038428427
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02434,047,822 - 34,114,743 (-)NCBI
RefSeq Acc Id: XM_038636772   ⟹   XP_038492700
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02433,508,812 - 33,575,667 (-)NCBI
RefSeq Acc Id: XM_543030   ⟹   XP_543030
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12433,424,567 - 33,492,162 (-)NCBI
Dog10K_Boxer_Tasha2432,950,778 - 33,018,325 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_543030   ⟸   XM_543030
- UniProtKB: A0A8P0NC70 (UniProtKB/TrEMBL),   A0A8C0KP06 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000014980   ⟸   ENSCAFT00000016196
RefSeq Acc Id: XP_038365094   ⟸   XM_038509166
RefSeq Acc Id: XP_038492700   ⟸   XM_038636772
RefSeq Acc Id: XP_038289935   ⟸   XM_038434007
- UniProtKB: A0A8C0KK01 (UniProtKB/TrEMBL),   A0A8I3NWW9 (UniProtKB/TrEMBL),   A0A8C0KP06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038428427   ⟸   XM_038572499
- UniProtKB: A0A8C0KP06 (UniProtKB/TrEMBL),   A0A8C0Q941 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845025762   ⟸   ENSCAFT00845032925
Protein Domains
Cadherin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000010175 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040006393 UniProtKB/TrEMBL
  ENSCAFG00845018625 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000016196.6 UniProtKB/TrEMBL
  ENSCAFT00040011910.1 UniProtKB/TrEMBL
  ENSCAFT00845032925 ENTREZGENE
  ENSCAFT00845032925.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.900.10 UniProtKB/TrEMBL
  Cadherins UniProtKB/TrEMBL
InterPro Cadherin UniProtKB/TrEMBL
  Cadherin-like_dom UniProtKB/TrEMBL
  Cadherin-like_sf UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/TrEMBL
  Cadherin_cytoplasmic-dom UniProtKB/TrEMBL
  Catenin-bd_sf UniProtKB/TrEMBL
NCBI Gene CDH22 ENTREZGENE
PANTHER CADHERIN-22 UniProtKB/TrEMBL
  PTHR24027 UniProtKB/TrEMBL
Pfam Cadherin UniProtKB/TrEMBL
  Cadherin_C UniProtKB/TrEMBL
PRINTS CADHERIN UniProtKB/TrEMBL
PROSITE CADHERIN_1 UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/TrEMBL
SMART SM00112 UniProtKB/TrEMBL
Superfamily-SCOP SSF49313 UniProtKB/TrEMBL
UniProt A0A8C0KK01 ENTREZGENE
  A0A8C0KP06 ENTREZGENE
  A0A8C0Q941 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NWW9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NC70 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:39030 ENTREZGENE