GPANK1 (G-patch domain and ankyrin repeats 1) - Rat Genome Database

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Gene: GPANK1 (G-patch domain and ankyrin repeats 1) Canis lupus familiaris
Analyze
Symbol: GPANK1
Name: G-patch domain and ankyrin repeats 1
RGD ID: 12401627
Description: ENCODES a protein that exhibits nucleic acid binding (inferred); ASSOCIATED WITH megacolon (ortholog); proteasome-associated autoinflammatory syndrome 1 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BAT4; G patch domain and ankyrin repeat-containing protein 1; HLA-B associated transcript 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,146,339 - 1,150,055 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,146,376 - 1,148,566 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,282,514 - 1,286,281 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,291,309 - 1,295,074 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,291,346 - 1,293,551 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,150,647 - 1,153,990 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,217,914 - 1,221,677 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,284,990 - 1,288,754 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GPANK1Dogmegacolon  ISORGD:13217668554872ClinVar Annotator: match by term: MegacolonClinVarPMID:21681106
GPANK1Dogproteasome-associated autoinflammatory syndrome 1  ISORGD:13217668554872ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1ClinVarPMID:28492532


Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GPANK1Dognucleic acid binding enablesIEAInterPro:IPR000467150520179 InterProGO_REF:0000002
GPANK1Dogprotein binding enablesISOPR:Q619379068941 PMID:15596447MGIPMID:15596447
GPANK1Dogprotein binding enablesISOUniProtKB:Q6DKK29068941 PMID:28514442, PMID:33961781IntActPMID:28514442|PMID:33961781
GPANK1Dogprotein binding enablesISOUniProtKB:O60333-2|UniProtKB:O76024|UniProtKB:P04792|UniProtKB:Q96CV9|UniProtKB:Q9Y3C59068941 PMID:32814053IntActPMID:32814053
GPANK1Dogprotein binding enablesISOUniProtKB:P14373|UniProtKB:P36406|UniProtKB:Q08379|UniProtKB:Q12800|UniProtKB:Q52MB2|UniProtKB:Q8ND909068941 PMID:25416956IntActPMID:25416956
GPANK1Dogprotein binding enablesISOUniProtKB:A2RRN7|UniProtKB:A6NEM1|UniProtKB:A6ZKI3|UniProtKB:A8MQ03|UniProtKB:A8MTA8-2|UniProtKB:G4XUV3|UniProtKB:O43143|UniProtKB:O43281-2|UniProtKB:O43482|UniProtKB:O60504|UniProtKB:O75031|UniProtKB:O95429|UniProtKB:O95678|UniProtKB:O95751|UniProtKB:P0C7X2|UniProtKB:P14373|UniProtKB:P26367|UniProtKB:P31943|UniProtKB:P36406|UniProtKB:P40199|UniProtKB:P50221|UniProtKB:P59991|UniProtKB:P60410|UniProtKB:P60510|UniProtKB:P61758|UniProtKB:P63010-2|UniProtKB:Q03431|UniProtKB:Q05516|UniProtKB:Q08117-2|UniProtKB:Q10567-3|UniProtKB:Q12933|UniProtKB:Q13133-3|UniProtKB:Q13190|UniProtKB:Q16610|UniProtKB:Q1MX18|UniProtKB:Q3LI70|UniProtKB:Q3LI72|UniProtKB:Q3SY46|UniProtKB:Q52MB2|UniProtKB:Q5W5X9-3|UniProtKB:Q63ZY3|UniProtKB:Q6DKK2|UniProtKB:Q6FHY5|UniProtKB:Q6IA69|UniProtKB:Q6PF18|UniProtKB:Q6PI77|UniProtKB:Q7L273|UniProtKB:Q86WV8|UniProtKB:Q8IWT0-2|UniProtKB:Q8N6F8|UniProtKB:Q8NI38|UniProtKB:Q8TCB7|UniProtKB:Q8WTU0|UniProtKB:Q96A72|UniProtKB:Q96EL1|UniProtKB:Q96N21|UniProtKB:Q99471|UniProtKB:Q99750|UniProtKB:Q9BRK4|UniProtKB:Q9BXJ5|UniProtKB:Q9BYU1|UniProtKB:Q9C0B1-2|UniProtKB:Q9H079|UniProtKB:Q9HBE1-4|UniProtKB:Q9HDD0|UniProtKB:Q9NQX0|UniProtKB:Q9NRI5-2|UniProtKB:Q9NYB9-2|UniProtKB:Q9NYG5-2|UniProtKB:Q9NZ72|UniProtKB:Q9UDW3|UniProtKB:Q9UFD9|UniProtKB:Q9UGI0|UniProtKB:Q9UJV3-2|UniProtKB:Q9UL33-2|UniProtKB:Q9ULX6|UniProtKB:Q9UM82|UniProtKB:Q9Y5V39068941 PMID:32296183IntActPMID:32296183
GPANK1Dogprotein binding enablesISOUniProtKB:Q9BRK49068941 PMID:21516116IntActPMID:21516116
GPANK1Dogprotein binding enablesISOUniProtKB:P14373|UniProtKB:P36406|UniProtKB:Q08379|UniProtKB:Q8ND909068941 PMID:31515488IntActPMID:31515488

PMID:22301074  



GPANK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,146,339 - 1,150,055 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,146,376 - 1,148,566 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,282,514 - 1,286,281 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,291,309 - 1,295,074 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,291,346 - 1,293,551 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,150,647 - 1,153,990 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,217,914 - 1,221,677 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,284,990 - 1,288,754 (-)NCBIUU_Cfam_GSD_1.0
GPANK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,661,228 - 31,666,283 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,661,228 - 31,666,283 (-)EnsemblGRCh38hg38GRCh38
GRCh37631,629,005 - 31,634,060 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,737,841 - 31,741,142 (-)NCBINCBI36Build 36hg18NCBI36
Build 34631,737,841 - 31,741,142NCBI
Celera633,228,083 - 33,231,384 (-)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,415,231 - 31,420,285 (-)NCBIHuRef
CHM1_1631,631,142 - 31,636,196 (-)NCBICHM1_1
T2T-CHM13v2.0631,514,261 - 31,519,317 (-)NCBIT2T-CHM13v2.0
Gpank1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,340,472 - 35,343,791 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,340,431 - 35,343,790 (+)EnsemblGRCm39 Ensembl
GRCm381735,121,448 - 35,124,815 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,121,455 - 35,124,814 (+)EnsemblGRCm38mm10GRCm38
MGSCv371735,258,441 - 35,261,760 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,731,008 - 34,732,862 (+)NCBIMGSCv36mm8
Celera1738,218,446 - 38,221,764 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.59NCBI
Gpank1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,702,309 - 3,705,476 (-)NCBIGRCr8
mRatBN7.2203,697,641 - 3,700,814 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,697,641 - 3,700,858 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,396,611 - 4,399,666 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,758,669 - 3,761,724 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,296,557 - 4,299,612 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,113,232 - 5,116,382 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,113,339 - 5,116,382 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,186,483 - 7,189,641 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,761,295 - 3,764,338 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1203,763,020 - 3,763,294 (-)NCBI
Celera204,324,958 - 4,328,001 (+)NCBICelera
Cytogenetic Map20p12NCBI
Gpank1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437207,735 - 211,104 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955437207,563 - 211,374 (-)NCBIChiLan1.0ChiLan1.0
GPANK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,139,122 - 46,143,033 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,100,639 - 42,104,541 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,323,258 - 31,327,461 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,213,136 - 32,217,344 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,213,136 - 32,217,344 (-)Ensemblpanpan1.1panPan2
Gpank1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,696,045 - 35,699,317 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,863,401 - 1,865,118 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,862,960 - 1,865,299 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPANK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,777,118 - 23,780,851 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,777,104 - 23,780,835 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,471,121 - 27,474,857 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GPANK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11740,358,652 - 40,362,734 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1740,359,961 - 40,362,547 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604431,572,930 - 31,577,278 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpank1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,538,634 - 24,545,561 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,537,770 - 24,541,845 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in GPANK1
38 total Variants


Assembly: CanFam3.1

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
12 1148446 1148447 G A snv Tibetan Mastiff (TM5), Spanish Water Dog (PE002), Chinese indigenous dogs (DQ8) View more Information
12 1148498 1148499 C A snv European Variation Archive Release 4, European Variation Archive Release 6, Greyhound (GY432) View more Information
12 1148503 1148504 C A snv Wolf (WO001_895), Jack Russell Terrier (JR0034), Dachshund (DH0117), Australian Terrier (AR001) View more Information




adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10



Ensembl Acc Id: ENSCAFT00000000927   ⟹   ENSCAFP00000000846
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl121,146,376 - 1,148,566 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845020222   ⟹   ENSCAFP00845015853
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl121,291,346 - 1,293,551 (-)Ensembl
RefSeq Acc Id: XM_005627150   ⟹   XP_005627207
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1121,146,339 - 1,149,312 (-)NCBI
Dog10K_Boxer_Tasha121,282,514 - 1,285,862 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038491336   ⟹   XP_038347264
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1121,150,647 - 1,153,990 (-)NCBI
RefSeq Acc Id: XM_038553528   ⟹   XP_038409456
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0121,284,990 - 1,288,754 (-)NCBI
RefSeq Acc Id: XM_038553529   ⟹   XP_038409457
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0121,284,990 - 1,288,335 (-)NCBI
RefSeq Acc Id: XM_038617418   ⟹   XP_038473346
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0121,217,914 - 1,221,677 (-)NCBI
RefSeq Acc Id: XM_038617419   ⟹   XP_038473347
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0121,217,914 - 1,221,258 (-)NCBI
RefSeq Acc Id: XM_038683003   ⟹   XP_038538931
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0121,291,309 - 1,295,074 (-)NCBI
RefSeq Acc Id: XM_038683004   ⟹   XP_038538932
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0121,291,309 - 1,294,655 (-)NCBI
RefSeq Acc Id: XM_538835   ⟹   XP_538835
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1121,146,339 - 1,150,055 (-)NCBI
Dog10K_Boxer_Tasha121,282,514 - 1,286,281 (-)NCBI
Sequence:
1 to 5 of 11 rows
1 to 5 of 11 rows
RefSeq Acc Id: XP_538835   ⟸   XM_538835
- UniProtKB: A0A8C0LB90 (UniProtKB/TrEMBL),   A0A8C0MAK7 (UniProtKB/TrEMBL),   A0A8I3RWH4 (UniProtKB/TrEMBL),   A0A8C0S7I4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005627207   ⟸   XM_005627150
- UniProtKB: A0A8C0LB90 (UniProtKB/TrEMBL),   A0A8C0MAK7 (UniProtKB/TrEMBL),   A0A8I3RWH4 (UniProtKB/TrEMBL),   A0A8C0S7I4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000000846   ⟸   ENSCAFT00000000927
RefSeq Acc Id: XP_038347264   ⟸   XM_038491336
RefSeq Acc Id: XP_038473346   ⟸   XM_038617418
G-patch



1 to 28 of 28 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCAFG00000000601 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030004488 UniProtKB/TrEMBL
  ENSCAFG00040010495 UniProtKB/TrEMBL
  ENSCAFG00845011410 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000000927.5 UniProtKB/TrEMBL
  ENSCAFT00030008241.1 UniProtKB/TrEMBL
  ENSCAFT00040019480.1 UniProtKB/TrEMBL
  ENSCAFT00845020222 ENTREZGENE
  ENSCAFT00845020222.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  G_patch_dom UniProtKB/TrEMBL
  GPANK1 UniProtKB/TrEMBL
KEGG Report cfa:481714 UniProtKB/TrEMBL
NCBI Gene GPANK1 ENTREZGENE
PANTHER G PATCH DOMAIN AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  PTHR20923 UniProtKB/TrEMBL
Pfam Ank_4 UniProtKB/TrEMBL
  G-patch UniProtKB/TrEMBL
PROSITE G_PATCH UniProtKB/TrEMBL
SMART G_patch UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt A0A8C0LB90 ENTREZGENE
  A0A8C0MAK7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0S7I4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RWH4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:41361 ENTREZGENE
1 to 28 of 28 rows