PPIL1 (peptidylprolyl isomerase like 1) - Rat Genome Database

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Gene: PPIL1 (peptidylprolyl isomerase like 1) Canis lupus familiaris
Analyze
Symbol: PPIL1
Name: peptidylprolyl isomerase like 1
RGD ID: 12388161
Description: ENCODES a protein that exhibits disordered domain specific binding (ortholog); INVOLVED IN embryonic brain development (ortholog); mRNA splicing, via spliceosome (ortholog); protein peptidyl-prolyl isomerization (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH genetic disease (ortholog); microcephaly (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nucleus (ortholog); U2-type catalytic step 2 spliceosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: peptidyl-prolyl cis-trans isomerase-like 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1125,916,524 - 5,936,276 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl125,917,228 - 5,942,943 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha125,935,566 - 5,961,058 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0126,265,629 - 6,291,138 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl126,265,627 - 6,290,391 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1125,920,562 - 5,946,039 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0126,000,037 - 6,025,485 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0126,098,346 - 6,123,792 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PPIL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1125,916,524 - 5,936,276 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl125,917,228 - 5,942,943 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha125,935,566 - 5,961,058 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0126,265,629 - 6,291,138 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl126,265,627 - 6,290,391 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1125,920,562 - 5,946,039 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0126,000,037 - 6,025,485 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0126,098,346 - 6,123,792 (-)NCBIUU_Cfam_GSD_1.0
PPIL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38636,854,829 - 36,874,803 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl636,854,827 - 36,874,803 (-)EnsemblGRCh38hg38GRCh38
GRCh37636,822,605 - 36,842,579 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36636,930,583 - 36,950,747 (-)NCBINCBI36Build 36hg18NCBI36
Build 34636,930,585 - 36,950,747NCBI
Celera638,377,637 - 38,397,836 (-)NCBICelera
Cytogenetic Map6p21.2NCBI
HuRef636,540,910 - 36,561,109 (-)NCBIHuRef
CHM1_1636,824,537 - 36,844,718 (-)NCBICHM1_1
T2T-CHM13v2.0636,675,439 - 36,695,414 (-)NCBIT2T-CHM13v2.0
Ppil1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391729,469,809 - 29,482,945 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1729,469,777 - 29,483,160 (-)EnsemblGRCm39 Ensembl
GRCm381729,250,835 - 29,263,971 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1729,250,803 - 29,264,186 (-)EnsemblGRCm38mm10GRCm38
MGSCv371729,387,780 - 29,400,916 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361728,977,847 - 28,990,983 (-)NCBIMGSCv36mm8
Celera1729,800,905 - 29,814,390 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1715.15NCBI
Ppil1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8207,303,919 - 7,323,962 (-)NCBIGRCr8
mRatBN7.2207,302,292 - 7,322,349 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl207,302,621 - 7,322,354 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx208,013,297 - 8,028,144 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0207,375,155 - 7,390,002 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0207,850,087 - 7,864,954 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0206,515,638 - 6,864,571 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl206,515,638 - 6,864,571 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0209,102,772 - 9,104,606 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0208,760,182 - 8,761,633 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4207,548,896 - 7,565,640 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1207,549,743 - 7,565,928 (-)NCBI
Celera208,852,048 - 8,866,821 (-)NCBICelera
Cytogenetic Map20p12NCBI
Ppil1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554376,131,013 - 6,143,529 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554376,131,013 - 6,143,474 (+)NCBIChiLan1.0ChiLan1.0
PPIL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2551,323,627 - 51,343,867 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1647,193,377 - 47,213,655 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0636,417,086 - 36,437,259 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1637,612,722 - 37,632,942 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl637,612,724 - 37,632,942 (-)Ensemblpanpan1.1panPan2
Ppil1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494641,389,370 - 41,407,501 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647622,552,566 - 22,571,001 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647622,552,484 - 22,570,860 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPIL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl732,522,733 - 32,547,839 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1732,522,736 - 32,547,874 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2737,426,210 - 37,451,342 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPIL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11735,260,471 - 35,281,367 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604436,798,831 - 36,819,128 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppil1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475420,976,515 - 20,985,393 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475420,976,765 - 20,985,408 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PPIL1
189 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014118403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038491673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038491674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038553900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038553901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038553902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038617760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038617761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038683355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038683356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038687218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000002223   ⟹   ENSCAFP00000002060
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl125,917,228 - 5,936,191 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000061572   ⟹   ENSCAFP00000057495
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl125,917,228 - 5,942,943 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845017522   ⟹   ENSCAFP00845013637
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl126,265,627 - 6,290,391 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845017554   ⟹   ENSCAFP00845013663
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl126,265,627 - 6,285,000 (-)Ensembl
RefSeq Acc Id: XM_014118403   ⟹   XP_013973878
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1125,916,524 - 5,936,276 (-)NCBI
Dog10K_Boxer_Tasha125,935,566 - 5,961,058 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038491673   ⟹   XP_038347601
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1125,920,562 - 5,946,039 (-)NCBI
RefSeq Acc Id: XM_038491674   ⟹   XP_038347602
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1125,920,562 - 5,946,039 (-)NCBI
RefSeq Acc Id: XM_038553900   ⟹   XP_038409828
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0126,098,346 - 6,123,792 (-)NCBI
RefSeq Acc Id: XM_038553901   ⟹   XP_038409829
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0126,098,346 - 6,122,015 (-)NCBI
RefSeq Acc Id: XM_038553902   ⟹   XP_038409830
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0126,098,346 - 6,123,792 (-)NCBI
RefSeq Acc Id: XM_038617760   ⟹   XP_038473688
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0126,000,037 - 6,025,485 (-)NCBI
RefSeq Acc Id: XM_038617761   ⟹   XP_038473689
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0126,000,037 - 6,025,485 (-)NCBI
RefSeq Acc Id: XM_038683355   ⟹   XP_038539283
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0126,265,629 - 6,291,138 (-)NCBI
RefSeq Acc Id: XM_038683356   ⟹   XP_038539284
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0126,265,629 - 6,291,138 (-)NCBI
RefSeq Acc Id: XM_038687218   ⟹   XP_038543146
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha125,935,566 - 5,961,058 (-)NCBI
RefSeq Acc Id: XP_013973878   ⟸   XM_014118403
- UniProtKB: A0A8C0K2R0 (UniProtKB/TrEMBL),   A0A8C0N2E1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000002060   ⟸   ENSCAFT00000002223
Ensembl Acc Id: ENSCAFP00000057495   ⟸   ENSCAFT00000061572
RefSeq Acc Id: XP_038347602   ⟸   XM_038491674
RefSeq Acc Id: XP_038347601   ⟸   XM_038491673
RefSeq Acc Id: XP_038473689   ⟸   XM_038617761
RefSeq Acc Id: XP_038473688   ⟸   XM_038617760
RefSeq Acc Id: XP_038539284   ⟸   XM_038683356
- UniProtKB: A0A8C0K2R0 (UniProtKB/TrEMBL),   A0A8C0N2E1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038539283   ⟸   XM_038683355
- UniProtKB: A0A8C0K2R0 (UniProtKB/TrEMBL),   A0A8C0N2E1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038543146   ⟸   XM_038687218
- UniProtKB: A0A8C0K2R0 (UniProtKB/TrEMBL),   A0A8C0N2E1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038409830   ⟸   XM_038553902
- UniProtKB: A0A8C0K2R0 (UniProtKB/TrEMBL),   A0A8C0N2E1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038409828   ⟸   XM_038553900
- UniProtKB: A0A8C0K2R0 (UniProtKB/TrEMBL),   A0A8C0N2E1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038409829   ⟸   XM_038553901
- UniProtKB: A0A8C0K2R0 (UniProtKB/TrEMBL),   A0A8C0N2E1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845013637   ⟸   ENSCAFT00845017522
Ensembl Acc Id: ENSCAFP00845013663   ⟸   ENSCAFT00845017554
Protein Domains
PPIase cyclophilin-type

Promoters
RGD ID:13685404
Promoter ID:EPDNEW_C3472
Type:multiple initiation site
Name:PPIL1_1
Description:peptidylprolyl isomerase like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1125,935,935 - 5,935,995EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001428 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030010831 UniProtKB/TrEMBL
  ENSCAFG00845009972 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000002223.5 UniProtKB/TrEMBL
  ENSCAFT00030020005.1 UniProtKB/TrEMBL
  ENSCAFT00845017522.1 UniProtKB/TrEMBL
  ENSCAFT00845017554.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.100.10 UniProtKB/TrEMBL
InterPro Cyclophilin-like_dom_sf UniProtKB/TrEMBL
  Cyclophilin-type_PPIase UniProtKB/TrEMBL
  Cyclophilin-type_PPIase_CS UniProtKB/TrEMBL
  Cyclophilin-type_PPIase_dom UniProtKB/TrEMBL
  Cyclophilin_A-like UniProtKB/TrEMBL
KEGG Report cfa:474891 UniProtKB/TrEMBL
NCBI Gene PPIL1 ENTREZGENE
PANTHER PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  PTHR45625 UniProtKB/TrEMBL
Pfam Pro_isomerase UniProtKB/TrEMBL
PIRSF Peptidylpro_ismrse UniProtKB/TrEMBL
PRINTS CSAPPISMRASE UniProtKB/TrEMBL
PROSITE CSA_PPIASE_1 UniProtKB/TrEMBL
  CSA_PPIASE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50891 UniProtKB/TrEMBL
UniProt A0A8C0K2R0 ENTREZGENE
  A0A8C0N2E1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NEJ5_CANLF UniProtKB/TrEMBL
  A0A8I3RXE8_CANLF UniProtKB/TrEMBL
  A0A8P0S7C9_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:44855 ENTREZGENE