Ppil1 (peptidylprolyl isomerase like 1) - Rat Genome Database

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Gene: Ppil1 (peptidylprolyl isomerase like 1) Heterocephalus glaber
Analyze
Symbol: Ppil1
Name: peptidylprolyl isomerase like 1
RGD ID: 18933300
Description: ENCODES a protein that exhibits cyclosporin A binding (inferred); disordered domain specific binding (inferred); peptidyl-prolyl cis-trans isomerase activity (inferred); INVOLVED IN embryonic brain development (inferred); mRNA splicing, via spliceosome (inferred); protein folding (inferred); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH genetic disease (ortholog); microcephaly (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN catalytic step 2 spliceosome (inferred); nucleus (inferred); spliceosomal complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Peptidyl-prolyl cis-trans isomerase-like 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475420,976,515 - 20,985,393 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475420,976,765 - 20,985,408 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ppil1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475420,976,515 - 20,985,393 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475420,976,765 - 20,985,408 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PPIL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38636,854,829 - 36,874,803 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl636,854,827 - 36,874,803 (-)EnsemblGRCh38hg38GRCh38
GRCh37636,822,605 - 36,842,579 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36636,930,583 - 36,950,747 (-)NCBINCBI36Build 36hg18NCBI36
Build 34636,930,585 - 36,950,747NCBI
Celera638,377,637 - 38,397,836 (-)NCBICelera
Cytogenetic Map6p21.2NCBI
HuRef636,540,910 - 36,561,109 (-)NCBIHuRef
CHM1_1636,824,537 - 36,844,718 (-)NCBICHM1_1
T2T-CHM13v2.0636,675,439 - 36,695,414 (-)NCBIT2T-CHM13v2.0
Ppil1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391729,469,809 - 29,482,945 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1729,469,777 - 29,483,160 (-)EnsemblGRCm39 Ensembl
GRCm381729,250,835 - 29,263,971 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1729,250,803 - 29,264,186 (-)EnsemblGRCm38mm10GRCm38
MGSCv371729,387,780 - 29,400,916 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361728,977,847 - 28,990,983 (-)NCBIMGSCv36mm8
Celera1729,800,905 - 29,814,390 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1715.15NCBI
Ppil1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8207,303,919 - 7,323,962 (-)NCBIGRCr8
mRatBN7.2207,302,292 - 7,322,349 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl207,302,621 - 7,322,354 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx208,013,297 - 8,028,144 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0207,375,155 - 7,390,002 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0207,850,087 - 7,864,954 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0206,515,638 - 6,864,571 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl206,515,638 - 6,864,571 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0209,102,772 - 9,104,606 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0208,760,182 - 8,761,633 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4207,548,896 - 7,565,640 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1207,549,743 - 7,565,928 (-)NCBI
Celera208,852,048 - 8,866,821 (-)NCBICelera
Cytogenetic Map20p12NCBI
Ppil1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554376,131,013 - 6,143,529 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554376,131,013 - 6,143,474 (+)NCBIChiLan1.0ChiLan1.0
PPIL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2551,323,627 - 51,343,867 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1647,193,377 - 47,213,655 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0636,417,086 - 36,437,259 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1637,612,722 - 37,632,942 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl637,612,724 - 37,632,942 (-)Ensemblpanpan1.1panPan2
PPIL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1125,916,524 - 5,936,276 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl125,917,228 - 5,942,943 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha125,935,566 - 5,961,058 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0126,265,629 - 6,291,138 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl126,265,627 - 6,290,391 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1125,920,562 - 5,946,039 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0126,000,037 - 6,025,485 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0126,098,346 - 6,123,792 (-)NCBIUU_Cfam_GSD_1.0
Ppil1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494641,389,370 - 41,407,501 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647622,552,566 - 22,571,001 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647622,552,484 - 22,570,860 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPIL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl732,522,733 - 32,547,839 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1732,522,736 - 32,547,874 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2737,426,210 - 37,451,342 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPIL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11735,260,471 - 35,281,367 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604436,798,831 - 36,819,128 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000024590   ⟹   ENSHGLP00000024370
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475420,976,515 - 20,985,393 (+)Ensembl
RefSeq Acc Id: XM_004846674   ⟹   XP_004846731
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475420,976,765 - 20,985,408 (+)NCBI
RefSeq Acc Id: XM_004846675   ⟹   XP_004846732
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475420,977,085 - 20,985,408 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004846731 (Get FASTA)   NCBI Sequence Viewer  
  XP_004846732 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB04399 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024370
  ENSHGLP00100034081
GenBank Protein JAO02575 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004846731   ⟸   XM_004846674
- Peptide Label: isoform X1
- UniProtKB: G5B538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004846732   ⟸   XM_004846675
- Peptide Label: isoform X2
RefSeq Acc Id: ENSHGLP00000024370   ⟸   ENSHGLT00000024590


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017369 Ensembl, ENTREZGENE
  ENSHGLG00100037766 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000024590 ENTREZGENE
  ENSHGLT00100055963 UniProtKB/TrEMBL
Gene3D-CATH 2.40.100.10 UniProtKB/TrEMBL
InterPro Cyclophilin-like_dom_sf UniProtKB/TrEMBL
  Cyclophilin-type_PPIase UniProtKB/TrEMBL
  Cyclophilin-type_PPIase_CS UniProtKB/TrEMBL
  Cyclophilin-type_PPIase_dom UniProtKB/TrEMBL
  Cyclophilin_A-like UniProtKB/TrEMBL
KEGG Report hgl:101709602 UniProtKB/TrEMBL
NCBI Gene Ppil1 ENTREZGENE
PANTHER PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  PTHR45625 UniProtKB/TrEMBL
Pfam Pro_isomerase UniProtKB/TrEMBL
PIRSF Peptidylpro_ismrse UniProtKB/TrEMBL
PRINTS CSAPPISMRASE UniProtKB/TrEMBL
PROSITE CSA_PPIASE_1 UniProtKB/TrEMBL
  CSA_PPIASE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50891 UniProtKB/TrEMBL
UniProt G5B538 ENTREZGENE, UniProtKB/TrEMBL