RNFT1 (ring finger protein, transmembrane 1) - Rat Genome Database

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Gene: RNFT1 (ring finger protein, transmembrane 1) Canis lupus familiaris
Analyze
Symbol: RNFT1
Name: ring finger protein, transmembrane 1
RGD ID: 12376260
Description: ENCODES a protein that exhibits ubiquitin binding (ortholog); INVOLVED IN protein autoubiquitination (ortholog); ASSOCIATED WITH Joubert syndrome 1 (ortholog); FOUND IN endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase RNFT1; RING finger and transmembrane domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1934,430,119 - 34,442,760 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl934,335,554 - 34,442,374 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha933,662,099 - 33,674,787 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0935,241,103 - 35,253,845 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl935,241,110 - 35,253,442 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1934,024,780 - 34,037,509 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0934,309,749 - 34,322,468 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0934,395,977 - 34,408,708 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
RNFT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1934,430,119 - 34,442,760 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl934,335,554 - 34,442,374 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha933,662,099 - 33,674,787 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0935,241,103 - 35,253,845 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl935,241,110 - 35,253,442 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1934,024,780 - 34,037,509 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0934,309,749 - 34,322,468 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0934,395,977 - 34,408,708 (-)NCBIUU_Cfam_GSD_1.0
RNFT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381759,952,240 - 59,964,740 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1759,952,240 - 59,964,761 (-)EnsemblGRCh38hg38GRCh38
GRCh371758,029,601 - 58,042,101 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361755,384,505 - 55,396,899 (-)NCBINCBI36Build 36hg18NCBI36
Celera1754,493,237 - 54,505,631 (-)NCBICelera
Cytogenetic Map17q23.1NCBI
HuRef1753,402,180 - 53,414,575 (-)NCBIHuRef
CHM1_11758,093,740 - 58,106,136 (-)NCBICHM1_1
T2T-CHM13v2.01760,820,980 - 60,833,476 (-)NCBIT2T-CHM13v2.0
Rnft1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391186,375,483 - 86,389,833 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1186,375,483 - 86,389,851 (+)EnsemblGRCm39 Ensembl
GRCm381186,484,657 - 86,499,007 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1186,484,657 - 86,499,025 (+)EnsemblGRCm38mm10GRCm38
MGSCv371186,298,159 - 86,312,509 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361186,300,852 - 86,315,202 (+)NCBIMGSCv36mm8
Celera1196,100,673 - 96,115,091 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1151.82NCBI
Rnft1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81071,807,403 - 71,821,132 (+)NCBIGRCr8
mRatBN7.21071,310,052 - 71,322,507 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1071,310,104 - 71,323,778 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1075,929,989 - 75,941,112 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01075,434,797 - 75,445,920 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01070,899,410 - 70,910,533 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01073,807,455 - 73,821,178 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1073,809,157 - 73,817,982 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01076,278,401 - 76,292,132 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41076,640,223 - 76,651,484 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1070,231,791 - 70,245,501 (+)NCBICelera
Cytogenetic Map10q26NCBI
Rnft1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554513,164,845 - 3,178,991 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554513,165,316 - 3,178,991 (+)NCBIChiLan1.0ChiLan1.0
RNFT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21976,113,925 - 76,126,370 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11780,924,130 - 80,937,015 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01754,016,689 - 54,029,100 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11758,858,294 - 58,869,908 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1758,858,416 - 58,869,908 (-)Ensemblpanpan1.1panPan2
Rnft1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560233,635,983 - 33,648,362 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364903,426,762 - 3,438,900 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364903,426,692 - 3,439,179 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNFT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1236,162,444 - 36,174,851 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11236,162,438 - 36,175,135 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21237,534,630 - 37,542,161 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNFT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11633,483,167 - 33,496,608 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1633,483,194 - 33,497,325 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660774,268,841 - 4,282,313 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnft1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248711,707,509 - 1,721,078 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248711,707,570 - 1,721,026 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RNFT1
125 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000043037   ⟹   ENSCAFP00000041394
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl934,335,554 - 34,442,374 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000071007   ⟹   ENSCAFP00000044052
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl934,335,554 - 34,442,374 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845046601   ⟹   ENSCAFP00845036587
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl935,241,110 - 35,253,442 (-)Ensembl
RefSeq Acc Id: XM_014116723   ⟹   XP_013972198
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1934,430,119 - 34,442,402 (-)NCBI
Dog10K_Boxer_Tasha933,662,099 - 33,674,387 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022423247   ⟹   XP_022278955
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1934,430,119 - 34,442,760 (-)NCBI
Dog10K_Boxer_Tasha933,662,099 - 33,674,787 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038486151   ⟹   XP_038342079
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1934,024,780 - 34,037,109 (-)NCBI
RefSeq Acc Id: XM_038486152   ⟹   XP_038342080
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1934,024,780 - 34,037,509 (-)NCBI
RefSeq Acc Id: XM_038547970   ⟹   XP_038403898
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0934,395,977 - 34,408,308 (-)NCBI
RefSeq Acc Id: XM_038547971   ⟹   XP_038403899
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0934,395,977 - 34,408,708 (-)NCBI
RefSeq Acc Id: XM_038611935   ⟹   XP_038467863
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0934,309,749 - 34,322,065 (-)NCBI
RefSeq Acc Id: XM_038611936   ⟹   XP_038467864
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0934,309,749 - 34,322,468 (-)NCBI
RefSeq Acc Id: XM_038677181   ⟹   XP_038533109
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0935,241,103 - 35,253,445 (-)NCBI
RefSeq Acc Id: XM_038677182   ⟹   XP_038533110
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0935,241,103 - 35,253,845 (-)NCBI
RefSeq Acc Id: XP_013972198   ⟸   XM_014116723
- UniProtKB: A0A8C0PJJ5 (UniProtKB/TrEMBL),   A0A8C0JM56 (UniProtKB/TrEMBL),   A0A8I3PSS3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022278955   ⟸   XM_022423247
- UniProtKB: A0A8C0PJJ5 (UniProtKB/TrEMBL),   A0A8C0JM56 (UniProtKB/TrEMBL),   A0A8I3PSS3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000041394   ⟸   ENSCAFT00000043037
Ensembl Acc Id: ENSCAFP00000044052   ⟸   ENSCAFT00000071007
RefSeq Acc Id: XP_038342080   ⟸   XM_038486152
RefSeq Acc Id: XP_038342079   ⟸   XM_038486151
RefSeq Acc Id: XP_038467864   ⟸   XM_038611936
RefSeq Acc Id: XP_038467863   ⟸   XM_038611935
RefSeq Acc Id: XP_038533110   ⟸   XM_038677182
- UniProtKB: A0A8C0PJJ5 (UniProtKB/TrEMBL),   A0A8C0JM56 (UniProtKB/TrEMBL),   A0A8I3PSS3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038533109   ⟸   XM_038677181
- UniProtKB: A0A8C0PJJ5 (UniProtKB/TrEMBL),   A0A8C0JM56 (UniProtKB/TrEMBL),   A0A8I3PSS3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403899   ⟸   XM_038547971
- UniProtKB: A0A8C0JM56 (UniProtKB/TrEMBL),   A0A8C0PJJ5 (UniProtKB/TrEMBL),   A0A8I3PSS3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403898   ⟸   XM_038547970
- UniProtKB: A0A8C0JM56 (UniProtKB/TrEMBL),   A0A8C0PJJ5 (UniProtKB/TrEMBL),   A0A8I3PSS3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845036587   ⟸   ENSCAFT00845046601
Protein Domains
RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000028780 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030025263 UniProtKB/TrEMBL
  ENSCAFG00040001677 UniProtKB/TrEMBL
  ENSCAFG00845026431 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000043037.3 UniProtKB/TrEMBL
  ENSCAFT00030046640.1 UniProtKB/TrEMBL
  ENSCAFT00040003179.1 UniProtKB/TrEMBL
  ENSCAFT00845046601 ENTREZGENE
  ENSCAFT00845046601.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro RNFT1/2 UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report cfa:480581 UniProtKB/TrEMBL
NCBI Gene RNFT1 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE RNFT1 UniProtKB/TrEMBL
  PTHR15860 UniProtKB/TrEMBL
Pfam zf-RING_2 UniProtKB/TrEMBL
PROSITE ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A8C0JM56 ENTREZGENE
  A0A8C0PJJ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PSS3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:45677 ENTREZGENE