EMC10 (ER membrane protein complex subunit 10) - Rat Genome Database

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Gene: EMC10 (ER membrane protein complex subunit 10) Canis lupus familiaris
Analyze
Symbol: EMC10
Name: ER membrane protein complex subunit 10
RGD ID: 12348245
Description: ENCODES a protein that exhibits membrane insertase activity (ortholog); INVOLVED IN positive regulation of endothelial cell migration (ortholog); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorder with Dysmorphic Facies and Variable Seizures (ortholog); FOUND IN extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C1H19orf63
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11106,254,498 - 106,261,212 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1106,236,307 - 106,261,113 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1105,827,559 - 105,834,314 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01106,765,525 - 106,772,280 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1106,764,511 - 106,772,195 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11106,437,585 - 106,444,475 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,079,193 - 106,085,948 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01106,919,850 - 106,926,607 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
EMC10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11106,254,498 - 106,261,212 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1106,236,307 - 106,261,113 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1105,827,559 - 105,834,314 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01106,765,525 - 106,772,280 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1106,764,511 - 106,772,195 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11106,437,585 - 106,444,475 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,079,193 - 106,085,948 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01106,919,850 - 106,926,607 (-)NCBIUU_Cfam_GSD_1.0
EMC10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381950,476,507 - 50,490,871 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1950,476,400 - 50,490,871 (+)EnsemblGRCh38hg38GRCh38
GRCh371950,979,764 - 50,994,128 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361955,671,548 - 55,678,420 (+)NCBINCBI36Build 36hg18NCBI36
Celera1948,029,877 - 48,036,747 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1947,317,584 - 47,324,456 (+)NCBIHuRef
CHM1_11950,981,479 - 50,988,350 (+)NCBICHM1_1
T2T-CHM13v2.01953,563,993 - 53,578,354 (+)NCBIT2T-CHM13v2.0
Emc10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,139,361 - 44,145,953 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,139,361 - 44,145,953 (-)EnsemblGRCm39 Ensembl
GRCm38744,489,937 - 44,496,524 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl744,489,937 - 44,496,529 (-)EnsemblGRCm38mm10GRCm38
MGSCv37751,745,308 - 51,751,883 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36744,358,169 - 44,364,450 (-)NCBIMGSCv36mm8
Celera739,939,859 - 39,946,434 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.83NCBI
Emc10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,119,040 - 104,125,409 (-)NCBIGRCr8
mRatBN7.2194,980,260 - 94,988,847 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl194,943,587 - 94,988,847 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1100,367,921 - 100,374,249 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01108,840,569 - 108,846,897 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,130,994 - 102,137,322 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01100,495,112 - 100,501,468 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1100,495,119 - 100,501,437 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01101,560,499 - 101,566,862 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4194,967,722 - 94,974,041 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,045,832 - 95,052,152 (-)NCBI
Celera189,245,087 - 89,251,415 (-)NCBICelera
Cytogenetic Map1q22NCBI
Emc10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955559672,039 - 676,473 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955559672,055 - 676,569 (-)NCBIChiLan1.0ChiLan1.0
EMC10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22056,542,978 - 56,549,842 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11958,463,734 - 58,470,604 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01947,440,309 - 47,447,199 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11956,341,505 - 56,348,394 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1956,341,503 - 56,352,725 (+)Ensemblpanpan1.1panPan2
Emc10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934922,412,714 - 22,420,154 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936889290,605 - 293,718 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936889288,704 - 296,144 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EMC10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl655,316,468 - 55,322,249 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1655,316,384 - 55,322,251 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2651,165,375 - 51,171,183 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EMC10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1643,537,612 - 43,544,579 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl643,537,689 - 43,543,435 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607323,525,972 - 23,533,236 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Emc10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248324,079,515 - 4,084,797 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248324,079,759 - 4,084,880 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EMC10
37 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000004761   ⟹   ENSCAFP00000004407
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1106,255,415 - 106,261,113 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000064418   ⟹   ENSCAFP00000055406
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1106,236,307 - 106,260,248 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000065685   ⟹   ENSCAFP00000047903
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1106,256,067 - 106,261,113 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000093452   ⟹   ENSCAFP00000062380
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1106,249,754 - 106,261,113 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845029684   ⟹   ENSCAFP00845023315
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1106,764,511 - 106,772,195 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845029713   ⟹   ENSCAFP00845023338
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1106,767,135 - 106,772,195 (-)Ensembl
RefSeq Acc Id: XM_038467391   ⟹   XP_038323319
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11106,437,585 - 106,444,475 (-)NCBI
RefSeq Acc Id: XM_038467392   ⟹   XP_038323320
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11106,438,874 - 106,444,475 (-)NCBI
RefSeq Acc Id: XM_038528089   ⟹   XP_038384017
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01106,919,850 - 106,926,607 (-)NCBI
RefSeq Acc Id: XM_038528090   ⟹   XP_038384018
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01106,921,141 - 106,926,607 (-)NCBI
RefSeq Acc Id: XM_038592386   ⟹   XP_038448314
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01106,079,193 - 106,085,948 (-)NCBI
RefSeq Acc Id: XM_038592387   ⟹   XP_038448315
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01106,080,482 - 106,085,948 (-)NCBI
RefSeq Acc Id: XM_038656178   ⟹   XP_038512106
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01106,765,525 - 106,772,280 (-)NCBI
RefSeq Acc Id: XM_038656179   ⟹   XP_038512107
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01106,766,814 - 106,772,280 (-)NCBI
RefSeq Acc Id: XM_541478   ⟹   XP_541478
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11106,254,498 - 106,261,212 (-)NCBI
Dog10K_Boxer_Tasha1105,827,559 - 105,834,314 (-)NCBI
Sequence:
RefSeq Acc Id: XM_858228   ⟹   XP_863321
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11106,255,748 - 106,261,212 (-)NCBI
Dog10K_Boxer_Tasha1105,828,848 - 105,834,314 (-)NCBI
Sequence:
RefSeq Acc Id: XP_541478   ⟸   XM_541478
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M3S3 (UniProtKB/TrEMBL),   A0A8C0L189 (UniProtKB/TrEMBL),   A0A8I3P0P8 (UniProtKB/TrEMBL),   A0A8C0L7F2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_863321   ⟸   XM_858228
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M3T3 (UniProtKB/TrEMBL),   A0A8I3NVZ8 (UniProtKB/TrEMBL),   A0A8C0L7F2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000055406   ⟸   ENSCAFT00000064418
Ensembl Acc Id: ENSCAFP00000004407   ⟸   ENSCAFT00000004761
Ensembl Acc Id: ENSCAFP00000062380   ⟸   ENSCAFT00000093452
Ensembl Acc Id: ENSCAFP00000047903   ⟸   ENSCAFT00000065685
RefSeq Acc Id: XP_038323319   ⟸   XM_038467391
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038323320   ⟸   XM_038467392
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038448314   ⟸   XM_038592386
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038448315   ⟸   XM_038592387
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038512106   ⟸   XM_038656178
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M3S3 (UniProtKB/TrEMBL),   A0A8C0L189 (UniProtKB/TrEMBL),   A0A8I3P0P8 (UniProtKB/TrEMBL),   A0A8C0L7F2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038512107   ⟸   XM_038656179
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M3T3 (UniProtKB/TrEMBL),   A0A8I3NVZ8 (UniProtKB/TrEMBL),   A0A8C0L7F2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038384017   ⟸   XM_038528089
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L189 (UniProtKB/TrEMBL),   A0A8C0L7F2 (UniProtKB/TrEMBL),   A0A8C0M3S3 (UniProtKB/TrEMBL),   A0A8I3P0P8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038384018   ⟸   XM_038528090
- Peptide Label: isoform X2
- UniProtKB: A0A8C0L7F2 (UniProtKB/TrEMBL),   A0A8C0M3T3 (UniProtKB/TrEMBL),   A0A8I3NVZ8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845023338   ⟸   ENSCAFT00845029713
Ensembl Acc Id: ENSCAFP00845023315   ⟸   ENSCAFT00845029684

Promoters
RGD ID:13682176
Promoter ID:EPDNEW_C245
Type:multiple initiation site
Name:EMC10_1
Description:ER membrane protein complex subunit 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11106,261,125 - 106,261,185EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002973 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030002288 UniProtKB/TrEMBL
  ENSCAFG00040011730 UniProtKB/TrEMBL
  ENSCAFG00845016751 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000004761.5 UniProtKB/TrEMBL
  ENSCAFT00000065685.2 UniProtKB/TrEMBL
  ENSCAFT00030004211.1 UniProtKB/TrEMBL
  ENSCAFT00030004225.1 UniProtKB/TrEMBL
  ENSCAFT00040021643.1 UniProtKB/TrEMBL
  ENSCAFT00040021672.1 UniProtKB/TrEMBL
  ENSCAFT00845029684 ENTREZGENE
  ENSCAFT00845029684.1 UniProtKB/TrEMBL
  ENSCAFT00845029713 ENTREZGENE
  ENSCAFT00845029713.1 UniProtKB/TrEMBL
InterPro Chrom_ER_Complex_Protein UniProtKB/TrEMBL
KEGG Report cfa:484362 UniProtKB/TrEMBL
NCBI Gene EMC10 ENTREZGENE
PANTHER CHROMATIN COMPLEXES SUBUNIT BAP18-RELATED UniProtKB/TrEMBL
  PTHR21397:SF4 UniProtKB/TrEMBL
Pfam ECM10 UniProtKB/TrEMBL
UniProt A0A8C0L189 ENTREZGENE
  A0A8C0L7F2 ENTREZGENE
  A0A8C0M3S3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0M3T3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NVZ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P0P8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40332 ENTREZGENE