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Gene: PPBP (pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)) Canis lupus familiaris

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Symbol:

PPBP

Name:

pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)

RGD ID:

12291950

Description:

ENCODES a protein that exhibits chemokine activity (inferred); cytokine activity (inferred); INVOLVED IN leukocyte migration involved in inflammatory response (ortholog); positive regulation of granulocyte chemotaxis (ortholog); ASSOCIATED WITH acute myocardial infarction (ortholog); adult respiratory distress syndrome (ortholog); allergic disease (ortholog); FOUND IN platelet alpha granule (ortholog)

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

chemokine C-X-C motif ligand 7; CXCL7; platelet basic protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PPBP (pro-platelet basic protein)	HGNC	EggNOG, Ensembl, Inparanoid, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Ppbp (pro-platelet basic protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Ppbp (pro-platelet basic protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PPBP (pro-platelet basic protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ppbp (pro-platelet basic protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PPBP (pro-platelet basic protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PPBP (pro-platelet basic protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	62,526,571 - 62,528,527 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	62,526,571 - 62,528,527 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	62,195,002 - 62,196,958 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	63,324,944 - 63,340,541 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	63,337,296 - 63,339,253 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	62,947,100 - 62,949,055 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	62,436,835 - 62,438,791 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	63,577,683 - 63,579,641 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PPBP	Dog	acute myocardial infarction	treatment	ISO	Ppbp (Rattus norvegicus)	9068941		RGD	PMID:29407168 and REF_RGD_ID:329901925
PPBP	Dog	adult respiratory distress syndrome		ISO	PPBP (Homo sapiens)	9068941	protein:increased expression:plasma and respiratory system fluid/secretion :	RGD	PMID:8498526 and REF_RGD_ID:401794588
PPBP	Dog	Angina Pectoris		ISO	PPBP (Homo sapiens)	9068941	protein:increased expression:plasma	RGD	PMID:17045893 and REF_RGD_ID:401794448
PPBP	Dog	antiphospholipid syndrome		ISO	PPBP (Homo sapiens)	9068941	protein:increased expression:plasma	RGD	PMID:26283469 and REF_RGD_ID:401794584
PPBP	Dog	aortic atherosclerosis		ISO	PPBP (Homo sapiens)	9068941	protein:increased expression:thrombus and artery	RGD	PMID:17045893 and REF_RGD_ID:401794448
PPBP	Dog	atrial fibrillation		ISO	PPBP (Homo sapiens)	9068941	protein:increased expression:plasma	RGD	PMID:2946878 and REF_RGD_ID:329901822
PPBP	Dog	atrial fibrillation		ISO	PPBP (Homo sapiens)	9068941	protein:increased expression:plasma:	RGD	PMID:37294500 and REF_RGD_ID:401794955
PPBP	Dog	brain ischemia		ISO	PPBP (Homo sapiens)	9068941		RGD	PMID:26307429 and REF_RGD_ID:11553187
PPBP	Dog	clear cell renal cell carcinoma	disease_progression	ISO	PPBP (Homo sapiens)	9068941		RGD	PMID:24335961 and REF_RGD_ID:401794956
PPBP	Dog	clear cell renal cell carcinoma	ameliorates	ISO	PPBP (Homo sapiens)	9068941		RGD	PMID:24335961 and REF_RGD_ID:401794956
PPBP	Dog	cocaine dependence		ISO	PPBP (Homo sapiens)	9068941	protein:increased expression:plasma	RGD	PMID:21806491 and REF_RGD_ID:401794583
PPBP	Dog	Coronary Disease		ISO	PPBP (Homo sapiens)	9068941	associated with menopause more ...	RGD	PMID:35734636 and REF_RGD_ID:401794436
PPBP	Dog	COVID-19		ISO	PPBP (Homo sapiens)	9068941	mRNA:decreased expression:CD8+ T cells (human)	RGD	PMID:32377375 and REF_RGD_ID:32716422
PPBP	Dog	Electric Burns		ISO	Ppbp (Rattus norvegicus)	9068941		RGD	PMID:29275615 and REF_RGD_ID:329901910
PPBP	Dog	familial hyperlipidemia		ISO	PPBP (Homo sapiens)	9068941	associated with menopause more ...	RGD	PMID:35734636 and REF_RGD_ID:401794436
PPBP	Dog	hypospadias		ISO	Ppbp (Rattus norvegicus)	9068941	protein:increased expression:blood	RGD	PMID:37059017 and REF_RGD_ID:401795478
PPBP	Dog	Hypothermia		ISO	Ppbp (Mus musculus)	9068941	protein:increased expression:plasma	RGD	PMID:31237986 and REF_RGD_ID:401794437
PPBP	Dog	limb ischemia		ISO	PPBP (Homo sapiens)	9068941	protein:increased expression:plasma	RGD	PMID:30638058 and REF_RGD_ID:401794451
PPBP	Dog	type 1 diabetes mellitus		ISO	PPBP (Homo sapiens)	9068941		RGD	PMID:14730686 and REF_RGD_ID:1625598
PPBP	Dog	Venous Thrombosis		ISO	PPBP (Homo sapiens)	9068941	associated with Wounds and Injuries and mRNA:increased expression:blood	RGD	PMID:32347511 and REF_RGD_ID:329901817
PPBP	Dog	Venous Thrombosis	ameliorates	ISO	Ppbp (Mus musculus)	9068941		RGD	PMID:23550035 and REF_RGD_ID:401794958

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PPBP	Dog	allergic disease		ISO	PPBP (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:23624239
PPBP	Dog	hypertension		ISO	PPBP (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:15513305 and PMID:6192689
PPBP	Dog	Lung Neoplasms		ISO	PPBP (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:27935865

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PPBP	Dog	antimicrobial humoral immune response mediated by antimicrobial peptide	involved_in	IBA	MGI:1861731 more ...	150520179		GO_Central	GO_REF:0000033
PPBP	Dog	cell chemotaxis	involved_in	IEA	GO:0008009	150520179		GOC	GO_REF:0000108
PPBP	Dog	cellular response to lipopolysaccharide	involved_in	IBA	PANTHER:PTN002564680 more ...	150520179		GO_Central	GO_REF:0000033
PPBP	Dog	chemotaxis	involved_in	IEA	InterPro:IPR033899	150520179		InterPro	GO_REF:0000002
PPBP	Dog	chemotaxis	involved_in	IEA	UniProtKB-KW:KW-0145	150520179		UniProt	GO_REF:0000043
PPBP	Dog	defense response	involved_in	IEA	InterPro:IPR033899	150520179		InterPro	GO_REF:0000002
PPBP	Dog	immune response	involved_in	IEA	InterPro:IPR001089 more ...	150520179		InterPro	GO_REF:0000002
PPBP	Dog	inflammatory response	involved_in	IBA	MGI:1339941 more ...	150520179		GO_Central	GO_REF:0000033
PPBP	Dog	leukocyte migration involved in inflammatory response	involved_in	IEA	UniProtKB:Q9EQI5 and ensembl:ENSMUSP00000031319	150520179		Ensembl	GO_REF:0000107
PPBP	Dog	leukocyte migration involved in inflammatory response	acts_upstream_of_or_within	ISO	MGI:3797508	9068941	PMID:23550035	MGI	PMID:23550035
PPBP	Dog	neutrophil chemotaxis	involved_in	IBA	MGI:1339941 more ...	150520179		GO_Central	GO_REF:0000033
PPBP	Dog	positive regulation of granulocyte chemotaxis		ISO	Ppbp (Rattus norvegicus)	9068941		RGD	PMID:15016410 and REF_RGD_ID:401795479
PPBP	Dog	signal transduction	involved_in	IEA	GO:0005125	150520179		GOC	GO_REF:0000108

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PPBP	Dog	extracellular region	located_in	IEA	InterPro:IPR001089 more ...	150520179		InterPro	GO_REF:0000002
PPBP	Dog	extracellular region	located_in	IEA	UniProtKB-SubCell:SL-0243	150520179		UniProt	GO_REF:0000044
PPBP	Dog	extracellular region	located_in	IEA	UniProtKB-KW:KW-0964	150520179		UniProt	GO_REF:0000043
PPBP	Dog	extracellular space	located_in	IEA	UniRule:UR000083251	150520179		UniProt	GO_REF:0000104
PPBP	Dog	extracellular space	is_active_in	IBA	MGI:1888499 more ...	150520179		GO_Central	GO_REF:0000033
PPBP	Dog	extracellular space	located_in	IEA	UniProtKB-KW:KW-0202	150520179		UniProt	GO_REF:0000043
PPBP	Dog	platelet alpha granule	located_in	ISO	PPBP (Homo sapiens)	9068941	PMID:10877842	UniProt	PMID:10877842

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PPBP	Dog	chemokine activity	enables	IEA	UniProtKB:Q9EQI5 and ensembl:ENSMUSP00000031319	150520179		Ensembl	GO_REF:0000107
PPBP	Dog	chemokine activity	enables	IBA	MGI:1339941 more ...	150520179		GO_Central	GO_REF:0000033
PPBP	Dog	chemokine activity	enables	IEA	InterPro:IPR001089 more ...	150520179		InterPro	GO_REF:0000002
PPBP	Dog	CXCR chemokine receptor binding	enables	IBA	MGI:1888499 more ...	150520179		GO_Central	GO_REF:0000033
PPBP	Dog	cytokine activity	enables	IEA	UniProtKB-KW:KW-0202	150520179		UniProt	GO_REF:0000043
PPBP	Dog	protein binding	enables	ISO	UniProtKB:P13501 and UniProtKB:Q07325	9068941	PMID:28381538	IntAct	PMID:28381538
PPBP	Dog	protein binding	enables	ISO	UniProtKB:O75400-2 more ...	9068941	PMID:32814053	IntAct	PMID:32814053

PMID:20022386	PMID:22301074	PMID:23136963	PMID:30032202

PPBP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	62,526,571 - 62,528,527 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	62,526,571 - 62,528,527 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	62,195,002 - 62,196,958 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	63,324,944 - 63,340,541 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	63,337,296 - 63,339,253 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	62,947,100 - 62,949,055 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	62,436,835 - 62,438,791 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	63,577,683 - 63,579,641 (+)	NCBI		UU_Cfam_GSD_1.0

PPBP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	73,986,439 - 73,988,190 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	73,985,966 - 73,988,276 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	74,852,156 - 74,853,907 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	75,071,619 - 75,072,764 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	75,217,792 - 75,218,935	NCBI
Celera	4	72,212,305 - 72,214,056 (-)	NCBI		Celera
Cytogenetic Map	4	q13.3	NCBI
HuRef	4	70,663,087 - 70,664,838 (-)	NCBI		HuRef
CHM1_1	4	74,888,045 - 74,889,796 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	77,330,080 - 77,331,831 (-)	NCBI		T2T-CHM13v2.0

Ppbp
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	90,916,377 - 90,917,922 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	90,916,377 - 90,917,922 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	90,768,518 - 90,770,063 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	90,768,518 - 90,770,063 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	91,197,544 - 91,199,086 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	91,843,718 - 91,845,260 (+)	NCBI		MGSCv36	mm8
Celera	5	88,920,145 - 88,921,687 (+)	NCBI		Celera
Cytogenetic Map	5	E1	NCBI
cM Map	5	44.78	NCBI

Ppbp
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	17,586,495 - 17,587,299 (-)	NCBI		GRCr8
mRatBN7.2	14	17,302,326 - 17,303,130 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	17,302,326 - 17,303,130 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	17,302,459 - 17,303,263 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	18,621,380 - 18,622,184 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	17,313,684 - 17,314,488 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	18,852,433 - 18,853,237 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	18,851,954 - 18,853,315 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	18,762,075 - 18,762,879 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	18,816,434 - 18,817,238 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	18,816,433 - 18,817,238 (-)	NCBI
Celera	14	16,678,302 - 16,679,106 (-)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

PPBP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	56,071,080 - 56,073,080 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	56,260,189 - 56,262,313 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	50,203,168 - 50,204,303 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	56,035,433 - 56,036,580 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	56,035,060 - 56,037,702 (+)	Ensembl	panpan1.1		panPan2

Ppbp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	13,267,431 - 13,268,872 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936598	1,719,480 - 1,720,911 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936598	1,719,501 - 1,720,890 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PPBP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	70,021,439 - 70,023,964 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	70,021,468 - 70,022,490 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	74,173,312 - 74,174,334 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PPBP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	22,470,670 - 22,471,841 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	22,470,573 - 22,471,809 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666084	305,796 - 308,564 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants in PPBP
36 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10


RefSeq Transcripts	NM_001171772	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038684541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GU187911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000048323 ⟹ ENSCAFP00000039975

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	13	62,526,571 - 62,528,527 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845011239 ⟹ ENSCAFP00845008769

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	13	63,337,296 - 63,339,253 (+)	Ensembl

RefSeq Acc Id:

NM_001171772 ⟹ NP_001165243

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	13	62,526,571 - 62,528,527 (+)	NCBI
Dog10K_Boxer_Tasha	13	62,195,002 - 62,196,958 (+)	NCBI
ROS_Cfam_1.0	13	63,337,296 - 63,339,253 (+)	NCBI
UMICH_Zoey_3.1	13	62,947,100 - 62,949,055 (+)	NCBI
UNSW_CanFamBas_1.0	13	62,436,835 - 62,438,791 (+)	NCBI
UU_Cfam_GSD_1.0	13	63,577,683 - 63,579,641 (+)	NCBI

Sequence:

show sequence

CTCCTGGGCAGCAGTTTGCCCTCACTCTGAGGTCTCCTGCCTCTAGGAACAGCTGTAGCTTGGTCTTCCCCACCATGAACCTCAGACCTAAGGCCACCTCCTCCTGTACCAACGCCAGCACTCTCCAG
GTCCTACGGGGGCTGCTGCTGCTGTCCCTGCTCCTGACTACACTCATCCCCACTGCTGGAGAAACTAAGAGTGTGGACTGTGAGCGGTTCTTGGAACTTCGCTGCATGTGTACAAAGACTGTCTCTGG
CATTCATCCAAGTAACATCCAAAACTTGGAGGTGCTCCGAGCAGGACCCCATTGTGCCAACGTCGAAGTGATAGCCATGCTGAAGAATGGGAAGAGAATCTGCCTGGACCCAGAAGCTCCCAAAATCA
AGAGAATAGTCCAGAAAATTTTGGAAAGTGCTGAGAGAACGGCATGACCTGTTCTCCTTCTGTCAAACTCTTTTATCCCCCACGAATGGTAGGAGTTTAAAGGCTTGACTCTCTGGAGTTCTTATTTA
TCCAAAACACCTATTTGCATTGTATGAAACTTTGGATATGTTTTCTATTCTGCCTCAAAAAGTCGCATGGTATTCTGGGAAGGCTGGTTAATAGATGCAAAGAGAAGGCGACAATAAGCAAACTTACA
TTCGAAATATAGTGTATGGTTTATTCTCTAACTCTTGGTTAAATGTGGCCCCTTGCTTTGCGTTCCTTTATTTAAAATTGTCTTTTCAAATACTTGCATGTGTGTTAACTTAGCTGGTTGTACTTTAC
TAGTTAGACTAGCTATGCCCATGATGATTAACAGATTCCATAATGGTCAATGATATTAGGAATTGCACAGAGCCCAGAATAGAGCATTTGTTCAATAAGTGTTTGTTAATTAATTTAGGCACGTAATA
GAGGTTTTCATTGTCTTAATCTTAGGATGTCTTCTTTCAAAGCATTTTCTGAAAGAGCTTTTAAGTGTTTATTTTAACCTTCAAACCCCAAAATAATAAAGTTGGATAATGTGAGTCTTATAAGCAGA
GGTAATTTATTTTAAAAAGAATATATTTAATCCTAGTGGAATAAAAAATATATGATGAAAAACATTAATATTCTCTATTTTTAAAAACTTCAGTATTTTCAATAATAATACTAATAACAATACAGGTT
CAGTATGGTGTTAAATGTTTTAACCAATCATGTTTCTATATATCTGTATTCACTTAATATCTGCCTGGTTACAATTTTAGTATTAGAATCAACCTTGTGAATGAGTGAAATAAAAAATGTAAACCTTA

hide sequence

RefSeq Acc Id:

XM_038684541 ⟹ XP_038540469

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	13	63,324,944 - 63,340,541 (+)	NCBI


Protein RefSeqs	NP_001165243	(Get FASTA)	NCBI Sequence Viewer
	XP_038540469	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ACZ72921	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000039975.1
	ENSCAFP00030032795.1
	ENSCAFP00040012457.1
	ENSCAFP00845008769
	ENSCAFP00845008769.1

RefSeq Acc Id:	NP_001165243 ⟸ NM_001171772
- Peptide Label:	precursor
- UniProtKB:	A0A8C0RPL3 (UniProtKB/TrEMBL), A0A8C0LMT4 (UniProtKB/TrEMBL), A0A8I3NDZ2 (UniProtKB/TrEMBL), D2K841 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNLRPKATSSCTNASTLQVLRGLLLLSLLLTTLIPTAGETKSVDCERFLELRCMCTKTVSGIHPSNIQNLEVLRAGPHCANVEVIAMLKNGKRICLDPEAPKIKRIVQKILESAERTA hide sequence

Ensembl Acc Id:

ENSCAFP00000039975 ⟸ ENSCAFT00000048323

RefSeq Acc Id:	XP_038540469 ⟸ XM_038684541
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSCAFP00845008769 ⟸ ENSCAFT00845011239

Protein Domains

Chemokine interleukin-8-like

RGD ID:

13685688

Promoter ID:

EPDNEW_C3756

Type:

single initiation site

Name:

PPBP_1

Description:

platelet basic protein precursor

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	13	62,526,558 - 62,526,618	EPDNEW

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000031174	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030020475	UniProtKB/TrEMBL
	ENSCAFG00040007743	UniProtKB/TrEMBL
	ENSCAFG00845006341	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000048323.3	UniProtKB/TrEMBL
	ENSCAFT00030037586.1	UniProtKB/TrEMBL
	ENSCAFT00040014399.1	UniProtKB/TrEMBL
	ENSCAFT00845011239	ENTREZGENE
	ENSCAFT00845011239.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.50.40	UniProtKB/TrEMBL
InterPro	Chemokine_b/g/d	UniProtKB/TrEMBL
	Chemokine_CXC	UniProtKB/TrEMBL
	Chemokine_CXC_CS	UniProtKB/TrEMBL
	Chemokine_IL8-like_dom	UniProtKB/TrEMBL
	CXC_Chemokine_domain	UniProtKB/TrEMBL
	Interleukin_8-like_sf	UniProtKB/TrEMBL
KEGG Report	cfa:482196	UniProtKB/TrEMBL
NCBI Gene	PPBP	ENTREZGENE
PANTHER	PLATELET BASIC PROTEIN	UniProtKB/TrEMBL
	SMALL INDUCIBLE CYTOKINE A	UniProtKB/TrEMBL
Pfam	IL8	UniProtKB/TrEMBL
PRINTS	INTERLEUKIN8	UniProtKB/TrEMBL
	SMALLCYTKCXC	UniProtKB/TrEMBL
PROSITE	SMALL_CYTOKINES_CXC	UniProtKB/TrEMBL
SMART	SCY	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54117	UniProtKB/TrEMBL
UniProt	A0A8C0LMT4	ENTREZGENE
	A0A8C0RPL3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NDZ2	ENTREZGENE, UniProtKB/TrEMBL
	D2K841	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - CTD