ZCCHC2 (zinc finger CCHC-type containing 2) - Rat Genome Database

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Gene: ZCCHC2 (zinc finger CCHC-type containing 2) Canis lupus familiaris
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Symbol: ZCCHC2
Name: zinc finger CCHC-type containing 2
RGD ID: 12287975
Description: ENCODES a protein that exhibits nucleic acid binding (inferred); phosphatidylinositol binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH bipolar disorder (ortholog); chromosome 18q deletion syndrome (ortholog); Human Influenza (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC111094598; uncharacterized LOC111094598; zinc finger CCHC domain-containing protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1114,335,727 - 14,393,157 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl114,337,065 - 14,393,158 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha115,297,086 - 15,360,133 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0114,190,236 - 14,253,286 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl114,191,690 - 14,254,282 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1114,231,483 - 14,289,704 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0114,159,498 - 14,222,500 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0114,410,914 - 14,469,185 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ZCCHC2Dogchromosome 18q deletion syndrome  ISOZCCHC2 (Homo sapiens)8554872ClinVar Annotator: match by term: Monosomy 18q and deletion 18qClinVarPMID:25741868 and PMID:31690835
ZCCHC2Dogmultiple congenital anomalies-hypotonia-seizures syndrome 1  ISOZCCHC2 (Homo sapiens)8554872ClinVar Annotator: match by term: Multiple congenital anomalies-hypotonia-seizures syndrome 1ClinVarPMID:10677500 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ZCCHC2Dogbipolar disorder  ISOZCCHC2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:31043756
ZCCHC2DogHuman Influenza  ISOZCCHC2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:23326326


Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ZCCHC2Dogcytoplasm located_inIEAUniProtKB:Q9C0B9 and ensembl:ENSP00000269499150520179 EnsemblGO_REF:0000107

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ZCCHC2Dognucleic acid binding enablesIEAInterPro:IPR001878 and InterPro:IPR036875150520179 InterProGO_REF:0000002
ZCCHC2Dogphosphatidylinositol binding enablesIEAInterPro:IPR036871150520179 InterProGO_REF:0000002
ZCCHC2Dogzinc ion binding enablesIEAInterPro:IPR001878 and InterPro:IPR036875150520179 InterProGO_REF:0000002
ZCCHC2Dogzinc ion binding enablesIEAUniProtKB-KW:KW-0863150520179 UniProtGO_REF:0000043

PMID:22301074  



ZCCHC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1114,335,727 - 14,393,157 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl114,337,065 - 14,393,158 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha115,297,086 - 15,360,133 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0114,190,236 - 14,253,286 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl114,191,690 - 14,254,282 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1114,231,483 - 14,289,704 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0114,159,498 - 14,222,500 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0114,410,914 - 14,469,185 (-)NCBIUU_Cfam_GSD_1.0
ZCCHC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381862,523,025 - 62,586,729 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1862,523,025 - 62,587,709 (+)EnsemblGRCh38hg38GRCh38
GRCh371860,190,258 - 60,253,962 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361858,357,894 - 58,396,798 (+)NCBINCBI36Build 36hg18NCBI36
Build 341858,357,893 - 58,396,796NCBI
Celera1856,910,014 - 56,965,120 (+)NCBICelera
Cytogenetic Map18q21.33NCBI
HuRef1856,901,978 - 56,956,933 (+)NCBIHuRef
CHM1_11860,186,189 - 60,241,233 (+)NCBICHM1_1
T2T-CHM13v2.01862,725,900 - 62,789,604 (+)NCBIT2T-CHM13v2.0
Zcchc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391105,916,929 - 105,961,807 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1105,918,136 - 105,961,804 (+)EnsemblGRCm39 Ensembl
GRCm381105,990,390 - 106,034,077 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1105,990,406 - 106,034,074 (+)EnsemblGRCm38mm10GRCm38
MGSCv371107,886,983 - 107,930,654 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361107,817,953 - 107,861,621 (+)NCBIMGSCv36mm8
Celera1108,839,603 - 108,883,221 (+)NCBICelera
Cytogenetic Map1E2.1NCBI
cM Map149.76NCBI
Zcchc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81322,621,275 - 22,708,232 (+)NCBIGRCr8
mRatBN7.21322,118,677 - 22,193,626 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1322,119,568 - 22,166,373 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1322,439,568 - 22,486,371 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01323,724,356 - 23,771,159 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01322,408,254 - 22,455,061 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01325,961,762 - 26,052,472 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1325,966,428 - 26,013,338 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01331,122,293 - 31,210,284 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41312,148,072 - 12,196,570 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11312,148,071 - 12,196,570 (+)NCBI
Celera1321,988,903 - 22,034,139 (+)NCBICelera
Cytogenetic Map13p11NCBI
Zcchc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540246,426,432 - 46,464,063 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540246,426,432 - 46,466,064 (+)NCBIChiLan1.0ChiLan1.0
ZCCHC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21780,044,446 - 80,107,909 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11865,737,056 - 65,800,519 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01855,893,099 - 55,948,648 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11859,210,876 - 59,265,634 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1859,209,993 - 59,265,634 (+)Ensemblpanpan1.1panPan2
Zcchc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494427,546,474 - 27,605,146 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364972,787,525 - 2,844,187 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364972,785,508 - 2,844,181 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZCCHC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1158,964,819 - 159,022,271 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11158,964,816 - 159,022,143 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21176,374,309 - 176,412,878 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZCCHC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11817,186,456 - 17,244,639 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1817,177,964 - 17,244,574 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660608,438,146 - 8,498,050 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zcchc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247928,239,931 - 8,298,508 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in ZCCHC2
538 total Variants



adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10



Ensembl Acc Id: ENSCAFT00000000126   ⟹   ENSCAFP00000000110
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl114,337,065 - 14,393,158 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845000020   ⟹   ENSCAFP00845000010
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl114,191,690 - 14,254,282 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845000022   ⟹   ENSCAFP00845000012
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl114,196,307 - 14,254,282 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845000024   ⟹   ENSCAFP00845000014
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl114,196,307 - 14,254,282 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845000029   ⟹   ENSCAFP00845000019
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl114,196,307 - 14,254,282 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845000033   ⟹   ENSCAFP00845000021
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl114,196,307 - 14,254,282 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845000035   ⟹   ENSCAFP00845000023
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl114,196,307 - 14,254,282 (-)Ensembl
RefSeq Acc Id: XM_022404738   ⟹   XP_022260446
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1114,335,727 - 14,393,157 (-)NCBI
Dog10K_Boxer_Tasha115,301,895 - 15,360,133 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038465258   ⟹   XP_038321186
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1114,231,483 - 14,289,704 (-)NCBI
RefSeq Acc Id: XM_038477527   ⟹   XP_038333455
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha115,297,086 - 15,360,133 (-)NCBI
RefSeq Acc Id: XM_038525862   ⟹   XP_038381790
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0114,410,914 - 14,469,185 (-)NCBI
RefSeq Acc Id: XM_038590173   ⟹   XP_038446101
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0114,164,315 - 14,222,500 (-)NCBI
RefSeq Acc Id: XM_038653997   ⟹   XP_038509925
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0114,195,050 - 14,253,286 (-)NCBI
RefSeq Acc Id: XR_005326359
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha115,297,086 - 15,360,133 (-)NCBI
RefSeq Acc Id: XR_005387999
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0114,159,498 - 14,222,500 (-)NCBI
RefSeq Acc Id: XR_005420948
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0114,190,236 - 14,253,286 (-)NCBI
1 to 5 of 13 rows
1 to 5 of 13 rows
RefSeq Acc Id: XP_022260446   ⟸   XM_022404738
- UniProtKB: A0A8I3MGU7 (UniProtKB/TrEMBL),   A0A8P0S638 (UniProtKB/TrEMBL),   A0A8I3M965 (UniProtKB/TrEMBL),   A0A8P0TL56 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000000110   ⟸   ENSCAFT00000000126
RefSeq Acc Id: XP_038321186   ⟸   XM_038465258
RefSeq Acc Id: XP_038446101   ⟸   XM_038590173
RefSeq Acc Id: XP_038509925   ⟸   XM_038653997
- UniProtKB: A0A8I3MGU7 (UniProtKB/TrEMBL),   A0A8P0S638 (UniProtKB/TrEMBL),   A0A8I3M965 (UniProtKB/TrEMBL),   A0A8P0TL56 (UniProtKB/TrEMBL)
CCHC-type



1 to 40 of 43 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCAFG00000000073 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00845000016 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000000126.6 UniProtKB/TrEMBL
  ENSCAFT00000096170.1 UniProtKB/TrEMBL
  ENSCAFT00000097648.1 UniProtKB/TrEMBL
  ENSCAFT00000098584.1 UniProtKB/TrEMBL
  ENSCAFT00000099727.1 UniProtKB/TrEMBL
  ENSCAFT00000100206.1 UniProtKB/TrEMBL
  ENSCAFT00845000020.1 UniProtKB/TrEMBL
  ENSCAFT00845000022 ENTREZGENE
  ENSCAFT00845000022.1 UniProtKB/TrEMBL
  ENSCAFT00845000024.1 UniProtKB/TrEMBL
  ENSCAFT00845000029.1 UniProtKB/TrEMBL
  ENSCAFT00845000033.1 UniProtKB/TrEMBL
  ENSCAFT00845000035.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1520.10 UniProtKB/TrEMBL
  Zinc finger, CCHC-type UniProtKB/TrEMBL
InterPro PX_dom_sf UniProtKB/TrEMBL
  ZCCHC2 UniProtKB/TrEMBL
  Znf_CCHC UniProtKB/TrEMBL
  Znf_CCHC_sf UniProtKB/TrEMBL
NCBI Gene ZCCHC2 ENTREZGENE
PANTHER PTHR46939 UniProtKB/TrEMBL
  ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
Pfam zf-CCHC UniProtKB/TrEMBL
PROSITE ZF_CCHC UniProtKB/TrEMBL
SMART ZnF_C2HC UniProtKB/TrEMBL
Superfamily-SCOP Formin homology 2 domain (FH2 domain) UniProtKB/TrEMBL
  SSF57756 UniProtKB/TrEMBL
  SSF64268 UniProtKB/TrEMBL
UniProt A0A8I3M965 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3M9M3_CANLF UniProtKB/TrEMBL
  A0A8I3MER8_CANLF UniProtKB/TrEMBL
  A0A8I3MFC4_CANLF UniProtKB/TrEMBL
  A0A8I3MGU7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MJI7_CANLF UniProtKB/TrEMBL
  A0A8P0PGY6_CANLF UniProtKB/TrEMBL
  A0A8P0PHM3_CANLF UniProtKB/TrEMBL
  A0A8P0PLP0_CANLF UniProtKB/TrEMBL
  A0A8P0S638 ENTREZGENE, UniProtKB/TrEMBL
1 to 40 of 43 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-14 ZCCHC2  zinc finger CCHC-type containing 2  LOC111094598  uncharacterized LOC111094598  Data merged from RGD:13424874 737654 PROVISIONAL