DMRT3 (doublesex and mab-3 related transcription factor 3) - Rat Genome Database
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Gene: DMRT3 (doublesex and mab-3 related transcription factor 3) Canis lupus familiaris
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Symbol: DMRT3
Name: doublesex and mab-3 related transcription factor 3
RGD ID: 12280577
Description: ENCODES a protein that exhibits sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN adult walking behavior (ortholog); male sex differentiation (ortholog); regulation of odontogenesis of dentin-containing tooth (ortholog); ASSOCIATED WITH primary ovarian insufficiency (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: doublesex- and mab-3-related transcription factor 3; duplex and mab-3 related transcription factor 3-like; LOC609208; LOW QUALITY PROTEIN: doublesex and mab-3 related transcription factor 3; LOW QUALITY PROTEIN: doublesex- and mab-3-related transcription factor 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl189,798,100 - 89,812,328 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1189,798,215 - 89,813,140 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,ISO)

References

Genomics

Comparative Map Data
DMRT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl189,798,100 - 89,812,328 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1189,798,215 - 89,813,140 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
DMRT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl9976,655 - 991,732 (+)EnsemblGRCh38hg38GRCh38
GRCh389976,655 - 991,732 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379976,655 - 991,732 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh379976,968 - 991,732 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369966,964 - 981,732 (+)NCBINCBI36hg18NCBI36
Build 349966,963 - 981,732NCBI
Celera9894,871 - 909,644 (+)NCBI
Cytogenetic Map9p24.3NCBI
HuRef9929,719 - 944,508 (+)NCBIHuRef
CHM1_19977,145 - 991,912 (+)NCBICHM1_1
Dmrt3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391925,587,609 - 25,601,285 (+)NCBIGRCm39mm39
GRCm381925,610,246 - 25,623,921 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1925,610,301 - 25,623,921 (+)EnsemblGRCm38mm10GRCm38
MGSCv371925,685,027 - 25,698,411 (+)NCBIGRCm37mm9NCBIm37
MGSCv361925,677,634 - 25,691,016 (+)NCBImm8
Celera1926,405,156 - 26,418,520 (+)NCBICelera
Cytogenetic Map19BNCBI
Dmrt3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21223,244,340 - 223,264,254 (+)NCBI
Rnor_6.0 Ensembl1243,589,607 - 243,602,926 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01243,589,607 - 243,602,926 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01250,848,350 - 250,861,669 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41229,044,302 - 229,058,689 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11229,206,114 - 229,222,715 (+)NCBI
Celera1220,451,183 - 220,464,645 (+)NCBICelera
Cytogenetic Map1q51NCBI
Dmrt3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554345,455,449 - 5,470,343 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554345,455,449 - 5,470,343 (+)NCBIChiLan1.0ChiLan1.0
DMRT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.19980,586 - 994,885 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v09786,402 - 801,114 (+)NCBIMhudiblu_PPA_v0panPan3
Dmrt3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365033,922,417 - 3,936,493 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DMRT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,820,556 - 220,833,835 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,819,525 - 220,834,080 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DMRT3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11278,528,709 - 78,543,509 (-)NCBI
ChlSab1.1 Ensembl1278,529,443 - 78,543,419 (-)Ensembl
Dmrt3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247365,648,318 - 5,662,301 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system integumental system nervous system reproductive system adipose tissue
High
Medium
Low 4 4 1
Below cutoff 1 1 2 6 6 7 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000003148   ⟹   ENSCAFP00000002924
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl189,798,100 - 89,812,328 (+)Ensembl
RefSeq Acc Id: XM_846422   ⟹   XP_851515
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1189,798,215 - 89,813,140 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038320958 (Get FASTA)   NCBI Sequence Viewer  
  XP_038381546 (Get FASTA)   NCBI Sequence Viewer  
  XP_038445749 (Get FASTA)   NCBI Sequence Viewer  
  XP_038509676 (Get FASTA)   NCBI Sequence Viewer  
  XP_851515 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_851515   ⟸   XM_846422
- Sequence:
RefSeq Acc Id: ENSCAFP00000002924   ⟸   ENSCAFT00000003148

Promoters
RGD ID:13682101
Promoter ID:EPDNEW_C168
Type:multiple initiation site
Name:DMRT3_1
Description:doublesex and mab-3 related transcription factor 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1189,798,178 - 89,798,238EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000023150 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000002924 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000003148 UniProtKB/TrEMBL
Gene3D-CATH 4.10.1040.10 UniProtKB/TrEMBL
InterPro DM_DNA-bd UniProtKB/TrEMBL
  DM_DNA-bd_sf UniProtKB/TrEMBL
  DMA UniProtKB/TrEMBL
  DMRT/dsx/mab-3 UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/TrEMBL
NCBI Gene LOC609208 ENTREZGENE
PANTHER PTHR12322 UniProtKB/TrEMBL
Pfam DMA UniProtKB/TrEMBL
  PF00751 UniProtKB/TrEMBL
PROSITE DM_1 UniProtKB/TrEMBL
  DM_2 UniProtKB/TrEMBL
SMART SM00301 UniProtKB/TrEMBL
Superfamily-SCOP SSF46934 UniProtKB/TrEMBL
  SSF82927 UniProtKB/TrEMBL
UniProt E2RLR2_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:49682 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-09-12 DMRT3  doublesex and mab-3 related transcription factor 3  LOC609208    Symbol and/or name change 5135510 APPROVED