ZCCHC3 (zinc finger CCHC-type containing 3) - Rat Genome Database

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Gene: ZCCHC3 (zinc finger CCHC-type containing 3) Canis lupus familiaris
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Symbol: ZCCHC3
Name: zinc finger CCHC-type containing 3
RGD ID: 12280184
Description: ENCODES a protein that exhibits double-stranded DNA binding (inferred); RNA binding (inferred); zinc ion binding (inferred); INVOLVED IN activation of innate immune response (inferred); cellular response to exogenous dsRNA (inferred); defense response to virus (inferred); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zinc finger CCHC domain-containing protein 3; zinc finger, CCHC domain containing 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12420,537,849 - 20,540,098 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2420,190,822 - 20,193,772 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02421,231,074 - 21,234,025 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2421,232,594 - 21,234,183 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12420,506,754 - 20,509,706 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02420,612,306 - 20,615,248 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02421,043,099 - 21,046,051 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ZCCHC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12420,537,849 - 20,540,098 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2420,190,822 - 20,193,772 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02421,231,074 - 21,234,025 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2421,232,594 - 21,234,183 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12420,506,754 - 20,509,706 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02420,612,306 - 20,615,248 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02421,043,099 - 21,046,051 (-)NCBIUU_Cfam_GSD_1.0
ZCCHC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3820297,570 - 300,321 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl20297,570 - 300,321 (+)EnsemblGRCh38hg38GRCh38
GRCh3720278,211 - 280,965 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3620226,204 - 228,965 (+)NCBINCBI36Build 36hg18NCBI36
Build 3420226,203 - 228,961NCBI
Celera20373,047 - 375,805 (+)NCBICelera
Cytogenetic Map20p13NCBI
HuRef20229,449 - 232,207 (+)NCBIHuRef
CHM1_120278,201 - 280,959 (+)NCBICHM1_1
T2T-CHM13v2.020340,752 - 343,503 (+)NCBIT2T-CHM13v2.0
Zcchc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392152,253,875 - 152,256,711 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2152,253,875 - 152,256,947 (-)EnsemblGRCm39 Ensembl
GRCm382152,411,956 - 152,415,044 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2152,411,955 - 152,415,027 (-)EnsemblGRCm38mm10GRCm38
MGSCv372152,237,692 - 152,240,780 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362152,104,396 - 152,106,468 (-)NCBIMGSCv36mm8
Celera2158,224,872 - 158,227,955 (-)NCBICelera
Cytogenetic Map2H1NCBI
cM Map274.98NCBI
Zcchc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83161,332,760 - 161,335,591 (-)NCBIGRCr8
mRatBN7.23140,872,460 - 140,875,292 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3140,872,460 - 140,882,408 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3144,777,641 - 144,780,474 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03153,361,487 - 153,364,319 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03151,101,349 - 151,104,179 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03147,877,321 - 147,881,434 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3147,878,936 - 147,880,138 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03154,225,218 - 154,228,259 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43142,727,648 - 142,730,465 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3139,624,087 - 139,628,200 (-)NCBICelera
Cytogenetic Map3q41NCBI
Zcchc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955597195,002 - 196,231 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955597194,912 - 197,697 (+)NCBIChiLan1.0ChiLan1.0
ZCCHC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2211,376,883 - 1,388,569 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1201,381,953 - 1,385,396 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v020504,967 - 508,354 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.120274,522 - 277,493 (+)NCBIpanpan1.1PanPan1.1panPan2
Zcchc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494472,532,832 - 72,547,892 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366703,048,914 - 3,049,809 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZCCHC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1734,882,816 - 34,885,505 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11734,882,812 - 34,885,632 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21739,662,491 - 39,665,335 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZCCHC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1235,422,903 - 35,426,145 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl235,423,430 - 35,424,638 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660787,594,906 - 7,598,250 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zcchc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247411,399,481 - 1,400,701 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247411,399,405 - 1,400,980 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZCCHC3
28 total Variants

Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCAFT00845030089   ⟹   ENSCAFP00845023598
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2421,232,594 - 21,234,183 (-)Ensembl
RefSeq Acc Id: XM_022409140   ⟹   XP_022264848
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12420,537,849 - 20,540,098 (-)NCBI
Dog10K_Boxer_Tasha2420,190,822 - 20,193,772 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038433408   ⟹   XP_038289336
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02421,231,074 - 21,234,025 (-)NCBI
RefSeq Acc Id: XM_038508612   ⟹   XP_038364540
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12420,506,754 - 20,509,706 (-)NCBI
RefSeq Acc Id: XM_038571903   ⟹   XP_038427831
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02421,043,099 - 21,046,051 (-)NCBI
RefSeq Acc Id: XM_038636157   ⟹   XP_038492085
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02420,612,306 - 20,615,248 (-)NCBI
RefSeq Acc Id: XP_022264848   ⟸   XM_022409140
- UniProtKB: A0A8C0JUZ9 (UniProtKB/TrEMBL),   A0A8P0PQX5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038364540   ⟸   XM_038508612
RefSeq Acc Id: XP_038492085   ⟸   XM_038636157
RefSeq Acc Id: XP_038289336   ⟸   XM_038433408
- UniProtKB: A0A8C0JUZ9 (UniProtKB/TrEMBL),   A0A8P0PQX5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038427831   ⟸   XM_038571903
- UniProtKB: A0A8C0JUZ9 (UniProtKB/TrEMBL),   A0A8P0PQX5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845023598   ⟸   ENSCAFT00845030089
Protein Domains
CCHC-type

Promoters
RGD ID:13687555
Promoter ID:EPDNEW_C5622
Type:single initiation site
Name:ZCCHC3_1
Description:zinc finger CCHC-type containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12420,540,605 - 20,540,665EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000056036 UniProtKB/TrEMBL
  ENSCAFG00845016991 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000100773.1 UniProtKB/TrEMBL
  ENSCAFT00845030089.1 UniProtKB/TrEMBL
Gene3D-CATH Zinc finger, CCHC-type UniProtKB/TrEMBL
InterPro ZCCHC3 UniProtKB/TrEMBL
  Znf_CCHC UniProtKB/TrEMBL
  Znf_CCHC_sf UniProtKB/TrEMBL
NCBI Gene ZCCHC3 ENTREZGENE
PANTHER PTHR22639 UniProtKB/TrEMBL
  ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
Pfam zf-CCHC UniProtKB/TrEMBL
PROSITE ZF_CCHC UniProtKB/TrEMBL
SMART ZnF_C2HC UniProtKB/TrEMBL
Superfamily-SCOP SSF57756 UniProtKB/TrEMBL
UniProt A0A8C0JUZ9 ENTREZGENE
  A0A8I3RZK8_CANLF UniProtKB/TrEMBL
  A0A8P0PQX5 ENTREZGENE, UniProtKB/TrEMBL