CCT4 (chaperonin containing TCP1 subunit 4) - Rat Genome Database

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Gene: CCT4 (chaperonin containing TCP1 subunit 4) Canis lupus familiaris
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Symbol: CCT4
Name: chaperonin containing TCP1 subunit 4
RGD ID: 12268901
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent protein folding chaperone (inferred); INVOLVED IN binding of sperm to zona pellucida (ortholog); positive regulation of protein localization to Cajal body (ortholog); positive regulation of telomere maintenance via telomerase (ortholog); ASSOCIATED WITH hereditary sensory neuropathy (ortholog); schizophrenia (ortholog); FOUND IN cell body (inferred); centrosome (inferred); chaperonin-containing T-complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: chaperonin containing TCP1, subunit 4 (delta); T-complex protein 1 subunit delta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11061,859,148 - 61,874,030 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1061,859,245 - 61,874,389 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1061,748,927 - 61,763,778 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01062,867,889 - 62,882,584 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1062,867,244 - 62,882,587 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11062,551,782 - 62,566,434 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01062,855,534 - 62,870,428 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01063,151,020 - 63,165,931 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202   PMID:30404858  


Genomics

Comparative Map Data
CCT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11061,859,148 - 61,874,030 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1061,859,245 - 61,874,389 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1061,748,927 - 61,763,778 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01062,867,889 - 62,882,584 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1062,867,244 - 62,882,587 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11062,551,782 - 62,566,434 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01062,855,534 - 62,870,428 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01063,151,020 - 63,165,931 (-)NCBIUU_Cfam_GSD_1.0
CCT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38261,868,085 - 61,888,671 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl261,868,085 - 61,888,671 (-)EnsemblGRCh38hg38GRCh38
GRCh37262,095,220 - 62,115,806 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36261,948,766 - 61,969,295 (-)NCBINCBI36Build 36hg18NCBI36
Build 34262,006,913 - 62,027,442NCBI
Celera261,940,173 - 61,960,736 (-)NCBICelera
Cytogenetic Map2p15NCBI
HuRef261,835,217 - 61,855,722 (-)NCBIHuRef
CHM1_1262,025,224 - 62,045,751 (-)NCBICHM1_1
T2T-CHM13v2.0261,874,246 - 61,894,829 (-)NCBIT2T-CHM13v2.0
Cct4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391122,940,593 - 22,953,336 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1122,940,519 - 22,953,780 (+)EnsemblGRCm39 Ensembl
GRCm381122,990,593 - 23,003,336 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1122,990,519 - 23,003,780 (+)EnsemblGRCm38mm10GRCm38
MGSCv371122,890,593 - 22,903,336 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361122,890,593 - 22,903,336 (+)NCBIMGSCv36mm8
Celera1125,126,226 - 25,138,969 (+)NCBICelera
Cytogenetic Map11A3.2NCBI
cM Map1114.25NCBI
Cct4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814101,193,057 - 101,205,935 (+)NCBIGRCr8
mRatBN7.21496,991,853 - 97,004,732 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1496,991,859 - 97,005,267 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx14101,325,100 - 101,337,974 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014102,567,399 - 102,580,273 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01499,039,002 - 99,051,876 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014107,767,392 - 107,780,270 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14107,767,392 - 107,780,270 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014107,843,411 - 107,856,260 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414103,675,110 - 103,687,893 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114103,694,320 - 103,707,104 (+)NCBI
Celera1495,973,133 - 95,985,983 (+)NCBICelera
Cytogenetic Map14q22NCBI
Cct4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542422,088,949 - 22,108,514 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542422,088,949 - 22,108,514 (+)NCBIChiLan1.0ChiLan1.0
CCT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21264,495,636 - 64,516,010 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A64,499,652 - 64,519,655 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A61,950,477 - 61,970,783 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A63,084,090 - 63,104,530 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A63,084,090 - 63,105,216 (-)Ensemblpanpan1.1panPan2
Cct4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629221,330,016 - 21,346,300 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364917,224,692 - 7,241,358 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364917,224,989 - 7,241,348 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl379,924,507 - 79,946,207 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1379,924,338 - 79,941,926 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2383,760,065 - 83,777,463 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11445,086,932 - 45,106,922 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1445,086,920 - 45,111,271 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604566,727,959 - 66,748,110 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cct4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462483346,076 - 62,665 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462483346,071 - 62,665 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCT4
219 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000004954   ⟹   ENSCAFP00000004593
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1061,859,245 - 61,874,389 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000091517   ⟹   ENSCAFP00000045163
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1061,859,245 - 61,874,389 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845029187   ⟹   ENSCAFP00845022954
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1062,867,244 - 62,882,587 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845029232   ⟹   ENSCAFP00845022989
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1062,867,244 - 62,882,587 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845029269   ⟹   ENSCAFP00845023018
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1062,869,168 - 62,882,587 (-)Ensembl
RefSeq Acc Id: XM_003639330   ⟹   XP_003639378
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11061,859,148 - 61,874,030 (-)NCBI
Dog10K_Boxer_Tasha1061,748,927 - 61,763,778 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038489398   ⟹   XP_038345326
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11062,551,782 - 62,566,434 (-)NCBI
RefSeq Acc Id: XM_038551377   ⟹   XP_038407305
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01063,151,020 - 63,165,931 (-)NCBI
RefSeq Acc Id: XM_038615314   ⟹   XP_038471242
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01062,855,534 - 62,870,428 (-)NCBI
RefSeq Acc Id: XM_038680700   ⟹   XP_038536628
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01062,867,889 - 62,882,584 (-)NCBI
RefSeq Acc Id: XP_003639378   ⟸   XM_003639330
- UniProtKB: A0A8C0NST9 (UniProtKB/TrEMBL),   A0A8P0N621 (UniProtKB/TrEMBL),   A0A8C0LSZ8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000004593   ⟸   ENSCAFT00000004954
Ensembl Acc Id: ENSCAFP00000045163   ⟸   ENSCAFT00000091517
RefSeq Acc Id: XP_038345326   ⟸   XM_038489398
RefSeq Acc Id: XP_038471242   ⟸   XM_038615314
RefSeq Acc Id: XP_038536628   ⟸   XM_038680700
- UniProtKB: A0A8C0Z750 (UniProtKB/TrEMBL),   A0A8I3P2D7 (UniProtKB/TrEMBL),   A0A8C0LSZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407305   ⟸   XM_038551377
- UniProtKB: A0A8C0LSZ8 (UniProtKB/TrEMBL),   A0A8C0NST9 (UniProtKB/TrEMBL),   A0A8P0N621 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845022954   ⟸   ENSCAFT00845029187
Ensembl Acc Id: ENSCAFP00845023018   ⟸   ENSCAFT00845029269
Ensembl Acc Id: ENSCAFP00845022989   ⟸   ENSCAFT00845029232


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003083 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030019079 UniProtKB/TrEMBL
  ENSCAFG00040025692 UniProtKB/TrEMBL
  ENSCAFG00845016454 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000004954.5 UniProtKB/TrEMBL
  ENSCAFT00000091517.2 UniProtKB/TrEMBL
  ENSCAFT00000107899.1 UniProtKB/TrEMBL
  ENSCAFT00030035266.1 UniProtKB/TrEMBL
  ENSCAFT00030035367.1 UniProtKB/TrEMBL
  ENSCAFT00030035398.1 UniProtKB/TrEMBL
  ENSCAFT00040047965.1 UniProtKB/TrEMBL
  ENSCAFT00040047974.1 UniProtKB/TrEMBL
  ENSCAFT00040047980.1 UniProtKB/TrEMBL
  ENSCAFT00845029187 ENTREZGENE
  ENSCAFT00845029187.1 UniProtKB/TrEMBL
  ENSCAFT00845029232.1 UniProtKB/TrEMBL
  ENSCAFT00845029269.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.560.10 UniProtKB/TrEMBL
  3.30.260.10 UniProtKB/TrEMBL
  3.50.7.10 UniProtKB/TrEMBL
InterPro Chap_CCT_delta UniProtKB/TrEMBL
  Chaperone_TCP-1 UniProtKB/TrEMBL
  Chaperonin_TCP-1_CS UniProtKB/TrEMBL
  Cpn60/TCP-1 UniProtKB/TrEMBL
  GroEL-like_apical_dom_sf UniProtKB/TrEMBL
  GROEL-like_equatorial_sf UniProtKB/TrEMBL
  TCP-1-like_intermed_sf UniProtKB/TrEMBL
  TCP-1_chaperonin UniProtKB/TrEMBL
  thermosome_alpha UniProtKB/TrEMBL
KEGG Report cfa:100855692 UniProtKB/TrEMBL
NCBI Gene CCT4 ENTREZGENE
PANTHER PTHR11353 UniProtKB/TrEMBL
  T-COMPLEX PROTEIN 1 SUBUNIT DELTA UniProtKB/TrEMBL
Pfam Cpn60_TCP1 UniProtKB/TrEMBL
PRINTS TCOMPLEXTCP1 UniProtKB/TrEMBL
PROSITE TCP1_1 UniProtKB/TrEMBL
  TCP1_2 UniProtKB/TrEMBL
  TCP1_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF48592 UniProtKB/TrEMBL
  SSF52029 UniProtKB/TrEMBL
  SSF54849 UniProtKB/TrEMBL
UniProt A0A8C0LSZ8 ENTREZGENE
  A0A8C0NST9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0NVL7_CANLF UniProtKB/TrEMBL
  A0A8C0NX15_CANLF UniProtKB/TrEMBL
  A0A8C0TUL0_CANLF UniProtKB/TrEMBL
  A0A8C0TXU3_CANLF UniProtKB/TrEMBL
  A0A8C0Z750 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NQN9_CANLF UniProtKB/TrEMBL
  A0A8I3P2D7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RZC2_CANLF UniProtKB/TrEMBL
  A0A8P0N621 ENTREZGENE
  A0A8P0PQ57_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0N621 UniProtKB/TrEMBL
  A0A8P0NVJ3 UniProtKB/TrEMBL
VGNC ID VGNC:38924 ENTREZGENE