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Gene: ONECUT1 (one cut homeobox 1) Canis lupus familiaris

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Symbol:

ONECUT1

Name:

one cut homeobox 1

RGD ID:

12217419

Description:

ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN anatomical structure morphogenesis (ortholog); B cell differentiation (ortholog); cell fate commitment (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); paraplegia (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

hepatocyte nuclear factor 6; one cut domain, family member 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ONECUT1 (one cut homeobox 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Onecut1 (one cut domain, family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Onecut1 (one cut homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Onecut1 (one cut homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ONECUT1 (one cut homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	LOC101960907 (uncharacterized LOC101960907)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ONECUT1 (one cut homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ONECUT1 (one cut homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Onecut1 (one cut homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	18,384,533 - 18,425,940 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	18,387,130 - 18,425,497 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	18,312,652 - 18,353,439 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	18,533,528 - 18,574,309 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	18,535,494 - 18,574,636 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	18,451,424 - 18,492,204 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	18,570,831 - 18,609,718 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	18,674,572 - 18,715,403 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bloom syndrome (ISO)

colorectal cancer (ISO)

paraplegia (ISO)

polycystic liver disease (ISO)

polycystic liver disease 1 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anatomical structure morphogenesis (IEA,ISO)

B cell differentiation (IEA,ISO)

cell fate commitment (IEA,ISO)

cell migration (IEA,ISO)

cilium assembly (IEA,ISO)

endocrine pancreas development (IEA,ISO)

endoderm development (IEA,ISO)

enteroendocrine cell differentiation (IEA,ISO)

epithelial cell development (IEA,ISO)

glucose metabolic process (IEA,ISO)

liver development (IEA,ISO)

negative regulation of transforming growth factor beta receptor signaling pathway (IEA,ISO)

Notch signaling pathway (IEA,ISO)

pancreas development (IEA,ISO)

pancreatic A cell differentiation (IEA,ISO)

pancreatic D cell differentiation (IEA,ISO)

positive regulation of cell migration (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of cell-matrix adhesion (IEA,ISO)

regulation of transcription by RNA polymerase II (IBA,IEA,ISO)

spleen development (IEA,ISO)

transforming growth factor beta receptor signaling pathway (IEA,ISO)

type B pancreatic cell differentiation (IEA,ISO)

Cellular Component

nucleoplasm (IEA)

nucleus (IBA,IEA)

Molecular Function

chromatin binding (IEA)

DNA binding (IEA,ISO)

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA,ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,IEA)

sequence-specific double-stranded DNA binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

ONECUT1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	18,384,533 - 18,425,940 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	18,387,130 - 18,425,497 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	18,312,652 - 18,353,439 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	18,533,528 - 18,574,309 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	18,535,494 - 18,574,636 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	18,451,424 - 18,492,204 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	18,570,831 - 18,609,718 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	18,674,572 - 18,715,403 (-)	NCBI		UU_Cfam_GSD_1.0

ONECUT1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	52,755,053 - 52,790,336 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	52,755,053 - 52,791,078 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	53,047,250 - 53,082,533 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	50,836,645 - 50,869,501 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	50,836,644 - 50,869,501	NCBI
Celera	15	29,944,311 - 29,977,184 (-)	NCBI		Celera
Cytogenetic Map	15	q21.3	NCBI
HuRef	15	29,879,668 - 29,912,665 (-)	NCBI		HuRef
CHM1_1	15	53,167,071 - 53,200,155 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	50,563,333 - 50,598,640 (-)	NCBI		T2T-CHM13v2.0

Onecut1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	74,769,203 - 74,796,930 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	74,769,203 - 74,799,063 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	74,861,921 - 74,889,648 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	74,861,921 - 74,891,781 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	74,709,728 - 74,737,455 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	74,648,524 - 74,676,252 (+)	NCBI		MGSCv36	mm8
Celera	9	72,045,890 - 72,046,250 (+)	NCBI		Celera
Cytogenetic Map	9	D	NCBI
cM Map	9	41.93	NCBI

Onecut1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	84,480,066 - 84,507,848 (+)	NCBI		GRCr8
mRatBN7.2	8	75,599,432 - 75,633,598 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	75,599,740 - 75,627,277 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	81,106,361 - 81,133,976 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	79,357,324 - 79,384,922 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	77,205,677 - 77,233,284 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	81,765,779 - 81,799,894 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	81,766,041 - 81,793,577 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	81,384,757 - 81,418,580 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	79,644,305 - 79,672,772 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	79,663,358 - 79,691,814 (+)	NCBI
Celera	8	75,394,297 - 75,421,855 (+)	NCBI		Celera
Cytogenetic Map	8	q24	NCBI

Onecut1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	2,181,346 - 2,207,888 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	2,181,364 - 2,214,636 (+)	NCBI	ChiLan1.0	ChiLan1.0

ONECUT1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	41,982,502 - 42,023,294 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	46,162,843 - 46,203,617 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	31,694,830 - 31,727,644 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	50,017,606 - 50,053,058 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	50,016,010 - 50,053,062 (-)	Ensembl	panpan1.1		panPan2

LOC101960907
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	96,722,333 - 96,733,257 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	14,532,892 - 14,566,904 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	14,532,888 - 14,581,258 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ONECUT1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	118,913,460 - 118,917,334 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	118,913,400 - 118,958,140 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	131,981,708 - 132,019,991 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ONECUT1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	30,609,392 - 30,645,996 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666048	110,585,853 - 110,622,490 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Onecut1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	7,911,264 - 7,939,434 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624731	7,911,352 - 7,938,440 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in ONECUT1
353 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038442370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038516822	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038580457	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038644759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_846134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000025139 ⟹ ENSCAFP00000023336

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	30	18,387,130 - 18,425,497 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845049309 ⟹ ENSCAFP00845038695

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	30	18,535,494 - 18,574,636 (-)	Ensembl

RefSeq Acc Id:

XM_038442370 ⟹ XP_038298298

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	30	18,533,528 - 18,574,309 (-)	NCBI

RefSeq Acc Id:

XM_038516822 ⟹ XP_038372750

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	30	18,451,424 - 18,492,204 (-)	NCBI

RefSeq Acc Id:

XM_038580457 ⟹ XP_038436385

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	30	18,674,572 - 18,715,403 (-)	NCBI

RefSeq Acc Id:

XM_038644759 ⟹ XP_038500687

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	30	18,570,831 - 18,609,718 (-)	NCBI

RefSeq Acc Id:

XM_846134 ⟹ XP_851227

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	30	18,384,533 - 18,425,940 (-)	NCBI
Dog10K_Boxer_Tasha	30	18,312,652 - 18,353,439 (-)	NCBI

Sequence:

show sequence

GCGGCGGCGGCGGCGGAACCGCGGCCACAGAGTCTGCAACAGTAACCGAGCCATGGCTGGAGCT
GGCCAGCGGCGCGGGCAAGCAGCAGCCGCGGAAGACGCGCGGACTGCGTCAGGGGAGCCGGGAG
CCTCAGAATCCTAAGAAGGAGAGGGGCGAGAGGGGGCCAGGGGCGGGCGGGCTGGGGGCGCCGC
GCTCGCCCACCGGCACGGATCCTTTTTGGAAATTAATATTTAAAAAAAAGCCGAGGACGCAGAG
GGGAAGGTGGGGGCAAGAGGGAAGGCGAGATATACAGAAAGGGAGACAGAGCCCCAGAGCGAGA
GGAAGGCAGGCGGGCAGGCGACAGTCGCCAGCAGCCGATGTGAAGACCGGACTGCGCGCGCCCT
TCGCCGCCTCTGCCCGGCCTCATCGATGTTGTGTCCGCCGCCCGCTCGCCCGGATCACGATGAA
CGCGCAGCTGACCATGGAGGCGATCGGCGAGCTGCACGGGGTGAGCCATGAGCCGGTGCCCGCT
CCTGCCGACCTCCTGGGCGGCAGTCCCCACGCGCGAAGCTCCGTGGCGCACCGTGGCAGCCACC
TGCCCCCCGCGCACCCGCGTTCCATGGGCATGGCGTCCTTGCTGGACGGCGGCGGCGGCGGCGG
CGATTACCACCACCACCACCGGGCCCCCGAGCACAGCCTGGCTGGCCCCCTGCACCCCACCATG
ACCATGGCCTGCGAGACTCCCCCAGGTATGAGCATGCCCACCACCTACACCACCTTAACCCCTC
TGCAGCCGCTGCCGCCCATCTCCACCGTCTCGGACAAGTTCCCTCACCATCACCACCACCACCA
CCACCATCACCATCCGCACCACCACCAGCGCCTGGCGGGCAACGTGAGCGGTAGCTTCACGCTC
ATGCGGGACGAGCGCGGGCTGGCCTCTATGAATAACCTCTATACCCCCTACCACAAGGACGTGG
CCGGCATGGGCCAGAGCCTCTCGCCCCTCTCCAGCTCCGGTCTCAGCGGCATCCACAACTCCCA
GCAAGGGCTCCCTCACTATGCCCACCCGGGCGCCGCCATGCCCACTGACAAGATGCTCACCCCG
AACGGCTTTGAAGCCCACCACCCGGCCATGCTCGGCCGTCACGGGGAGCAGCACCTCACGCCCA
CCTCGGCCGGCATGGTGCCCATAAACGGCCTTCCTCCGCACCACCCCCACGCCCACCTGAACGC
CCAGGGCCACGGGCAGCTCCTGGGCACGGCCCGGGAGCCCAACCCTTCGGTGACCGGAGCACAG
GTCAGCAATGGAAGTAATTCAGGGCAGATGGAAGAGATCAATACCAAAGAGGTGGCGCAGCGTA
TCACCACCGAGCTCAAGCGCTACAGCATCCCACAGGCCATCTTCGCGCAGAGGGTGCTCTGCCG
CTCCCAAGGGACCCTCTCGGACCTGCTGCGCAACCCCAAACCCTGGAGCAAACTCAAGTCCGGC
CGGGAGACCTTCCGGAGGATGTGGAAGTGGCTGCAGGAGCCGGAGTTCCAGCGGATGTCTGCGC
TCCGCTTAGCAGCTTGCAAAAGGAAAGAACAAGAACATGGGAAGGATAGAGGCAACACACCCAA
AAAGCCCAGGTTGGTCTTCACAGATGTCCAGCGTCGAACTCTACATGCAATATTCAAGGAAAAT
AAGCGTCCATCCAAAGAATTGCAAATCACTATTTCCCAGCAGCTGGGGTTGGAGCTGAGCACCG
TGAGCAATTTCTTCATGAATGCAAGGAGGAGGAGTCTGGACAAGTGGCAGGACGAGGGCAGCTC
CAATTCAGGCAACTCATCTTCTTCATCAAGCACTTGTACCAAAGCATGAAGGAATAACCACGAA
CTAAACCTCGGTGGAAAAGCTTTAAATTAAAAAAAAAAAAATTTTTAAAAGACCAGGACCTCAA
GATAGCAGGTTTATACTTAGAAATATTTGAAGAAGAAAAAAAAGTGTTATTTATAGTCCAAAGA
AACCAAAGACTTAGCTCACCTGCATTCTGACTTTGTTCGGAGACACACACTTCAGCGGGGCAAC
GACTTGGCAAGAAAAATTATGAGCAGGAAAGCACCACTGGATCTCACACCTTCAATCCATGATC
ATTCTCGCTGTGCTTGGCTGTTTCGTGGTTTGGAGCATAGTGATTTTGAGCCATTGAGTGGACA
TCTTTTAAGATCAGACTTTCTCATCTGTTCCACCATGCCATGAAGGTGTATGGTGTCTCAGTAC
TGTGTGTGGGTACGTGAGTGCATACACACACACACACACACACACATACACACACATATGCACA
CACCACCAGTGGTTAGGGACTTAGGCAGGGCTGGTCTTCAGGAAGGGTTGTGCTATAGGAGTAC
AACCAACATAGTGTGGGTTGTCTGAGTTCATTGGATAGGAGTGTGATTTCACTCGTCTAGCCTA
GCGTTTGAACCTGCCAGGCCCGCAACCTAAATGCAGATTCAAACCCAGCAAAGAAAATTTGAAT
GACACCTAAACCAGTGCATTCTCTTTGTTTGTTAAGGAATGTTCAGATATTTTTTAAGAAATGA
AACAAGAGTCCATCCATTTAAAAAAAAATCACCTAGGTACCAAAGAACACAATATTATAGTGCA
GGTATTTTATTGCAATGATTTTAATAACCAAAGCTATTTTTACACAAGATGCTATGTAAAGTTA
TACGTATGAACTGATCTAGCTGTAATACACATGCCACATAGAATCATGACTATTATTTATGACT
CTGGAAGCATTTGAAATATTAGTTTTCAGAACTGGCAAGAAAGAATGTAGCTTCAGGGAAGCAA
TTAATATCATAACAGAGAGGTCAATGTAGTGTACATGTACGTCCAGATGGCACAGTCCCTTTTG
GGATCCATAAATGATACTTAAATAGACACACAGACATGATGCCATAGTCTATTCATAGCTGAGA
AAACCTGGGGATTCTTCCAAAGTAGGACCCCATTTGTAAATTAGAAAACTAAGTTTAACAGAAC
AAGTAATTAAATTAGAAAATTTGTTCTAAGTAATGCTATTTTTTAGTAAAAGACCATTAAATAA
AGGATATCATATTTAGGTTAATTTGACTTAAAGTTGCTTTTTGCATTTGACACCAAATACCCTT
TTAAAATACTTTGTAAACACACAAAGTGAACAGACCAAATTATTATAAAAATAAACTGTCCAGT
ATTTGTAGTTAAATTGATTTTATTGCCAGTCTCGGATAGTTTATGACTTAGACATCAATAAAAC
TAGCAGATGTAACTGAGAAATGGTGTAACAGCATAGAAAAAAAAAACAGAATTCTAGTGGAAGA
CAAGACTTTGGGCTCTACAGGCTTGAAGCTATTTATTTCACTAAGCATAGCCTCCAAAGTGTAC
TACATTCTTTCTTGCTATGGCATTAAGCTGGAAGTTTTTTGACATAAAGTCCACTCTCTAACAG
GAACAGATAAAACACTAGACCTGAGTTTCCAAATACAAAATTTTCAATTTCTGTTTTTCCAAAT
CACTTACCTACAGCTGGAGAAATCAAGGGGGAAGAAAAAAGCTGACACAGTTGCATTGGTAGTA
CCTAAGGGAATCACTTGCTTCTCAGAAAAATTCTCTCTGAATTCATTGAACTGTGACTCATAGA
AGTGGATACCTTTTGTACTATTAGGTAAAGAACTGGGTGCTCTTGGTTAATTACCACACCTAAT
TAGAAATATAAAATGAAATGTTGTCTCCACAATAAGTTGTTGATTGAGATTCATTAAAATGCTA
AAGAAAAAAAAACTTGAACCACCTTGACACAAAAACCTAACTCCCTAAGGTCAAATCAGGAGCA
TCTAGGTCTATAGAGGTCTAGAAGAGACAGGCACCTGGAGAGGAAGCTAAAGCAACAAGCCATC
GGGATCTCCTTCATGTCTGCTATAGAATAAGAAAAGCAAACCAACACATACTTCTCCTTTAATG
AAATAGCGCATTTGCCTTGACACATTTTGTTTTAGTATTTTCTTTTAATCTCACACCAAATTCC
AGCTTAAAATTTTCCCTTCTAAACATGGCACAATTACAACTCAACTATTAAAAGAGACCATTTC
AATGGCTACCCTTAGAGAGATGCTTAACATATGATCTTGTCAATGACACAAACCAAAAGGAAAA
GACTAATTAACTTTTTCTCTCTCTCCAGAATGGAGGGGGCCAGGAGTACAGCTGTATAGTTCTA
ATTTAGGAGGGAGGAAAGCCTTATTTATTTAAAACATGAGAGTTTTAAATGCAGGGAAATTCAA
GCTGTGTCTACACACAATCTTACCAAATTCAGCACCCCAGGAAAAACAAAAGTTGAGTTCAAAC
ACCATGCTTTTTGTTTTGTTTTTGCTATATTACTCCGTCAGGTTAATCCAATTGCATTTTACGT
TTTCAACCAATTATTTTGGTACTGTGTAGACACAGTCTCAAAGAATATTACTATATCTCTAATA
TTCCCATCATAATAGTTTTTTTGAAAAATAATCCATGATCCTACTTGCTAACACCAAAGATAAT
TTTCATACCAGCATTGAATTTGCACCCATCACATAGTTTCAGGGCCTAGAGATATATTTTCTCA
TGAACAGATGCACAAATCAGAGCCTGAAAAGCAATTTTTTTACTAGACTGTTCAAGCATACTCA
CAACCTTTGCTGTTTAGAAATAATAATAGACAAACTCAGCTTCTCACAAGCAATACACTCTTAC
TTCATGTATGACTGATTATTGCTTCTAACTTGGCATGTAGCATAAATTTATGGCTCAGGTTTTT
TAACCTACCACATTCAGTGGAGCAGATTACGTGCCATTTGCTCACCCATTATTTCTCAATCCTT
TTGCAAAATCCATCCAAAAAAGGTATCCCACACTTTTATTGGTATATTTGTTTTTTCCCACACT
GCACATCACATAACATGTTTGGGGTTTTTTTTGGTAGAATGGAAGTTAAACTGTTTTTGACCAG
ACATCATTCAGGTCCTCTCATGACTGCAAGCTTCCCTCAAAGGAGGCAAAGACAGAGAGCGTGG
GAGATATGACATCTGGACTCTCCAAAAGCCCAGATTTCAGTAAGTGTTCAGGTAGGTAAATGAA
TTCTGGATGTCAGGAACTAAGTATTTAGTCCTGGATGCAGCTGGTATAGATCCCTAAACCCAAA
GAGAATGTGGAGAAATTCAGGCATTCAAACTGAACAGGTCACTCTTCATTGAAAAAAAAAAAAA
AAAGCATAATTACATTTCCAGGACAAAAAAGTAAAAGTACTATGCTCCTTTTGGACTCATGCCA
CTCCCATTGCTACCCCAGGTGAATGATCCGTCTTTGCAGGTTAAATGCAAACTTTGCTATACCA
AAGAGTCCTAGGACATTTTCACAAGAGCTATAAAGGCATTTTCCCTAAAAAGGTTCTCCCTTCT
TTGTACATAAAGGATGAAAACTATGCATTTAGCAAACAAAGAGAAAGCACTTCTCCCTTTCCTA
TCTAGTTGTTTAGGGTGCATTCAAACACCAGAGGCCATTTTGAGATGCGATTGGCCTTCTGGAT
TATTCTTGTGGTGTGGTTAGCTTTACAGTACATTTGGTAACTATTTCCTAAATAGTAAGGACAA
AGAAGCAGAAGGTAAGAAATAGCTACTTCCATGTGTTAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAG

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Protein Sequences


Protein RefSeqs	XP_038298298	(Get FASTA)	NCBI Sequence Viewer
	XP_038372750	(Get FASTA)	NCBI Sequence Viewer
	XP_038436385	(Get FASTA)	NCBI Sequence Viewer
	XP_038500687	(Get FASTA)	NCBI Sequence Viewer
	XP_851227	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000023336.4
	ENSCAFP00030025845.1
	ENSCAFP00040041566.1
	ENSCAFP00845038695
	ENSCAFP00845038695.1

RefSeq Acc Id:

XP_851227 ⟸ XM_846134

- UniProtKB:

A0A8C0NJ34 (UniProtKB/TrEMBL), A0A8C0R076 (UniProtKB/TrEMBL), A0A8I3PVL4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPRSMGMASLLDGGGG
GGDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHHHHH
HHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLSPLSSSGLSGIHN
SQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTPTSAGMVPINGLPPHHPHAHL
NAQGHGQLLGTAREPNPSVTGAQVSNGSNSGQMEEINTKEVAQRITTELKRYSIPQAIFAQRVL
CRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEHGKDRGNT
PKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDEG
SSNSGNSSSSSSTCTKA

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Ensembl Acc Id:

ENSCAFP00000023336 ⟸ ENSCAFT00000025139

RefSeq Acc Id:

XP_038372750 ⟸ XM_038516822

RefSeq Acc Id:

XP_038500687 ⟸ XM_038644759

RefSeq Acc Id:	XP_038298298 ⟸ XM_038442370
- UniProtKB:	A0A8C0NJ34 (UniProtKB/TrEMBL), A0A8C0R076 (UniProtKB/TrEMBL), A0A8I3PVL4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038436385 ⟸ XM_038580457
- UniProtKB:	A0A8C0NJ34 (UniProtKB/TrEMBL), A0A8C0R076 (UniProtKB/TrEMBL), A0A8I3PVL4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845038695 ⟸ ENSCAFT00845049309

Protein Domains

CUT Homeobox

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000015867	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030016134	UniProtKB/TrEMBL
	ENSCAFG00040025506	UniProtKB/TrEMBL
	ENSCAFG00845027935	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000025139.6	UniProtKB/TrEMBL
	ENSCAFT00030029662.1	UniProtKB/TrEMBL
	ENSCAFT00040047612.1	UniProtKB/TrEMBL
	ENSCAFT00845049309	ENTREZGENE
	ENSCAFT00845049309.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.260.40	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
InterPro	CUT_dom	UniProtKB/TrEMBL
	CUT_Homeobox	UniProtKB/TrEMBL
	Homeobox-like_sf	UniProtKB/TrEMBL
	Homeobox_dom	UniProtKB/TrEMBL
	Lambda_DNA-bd_dom_sf	UniProtKB/TrEMBL
KEGG Report	cfa:487558	UniProtKB/TrEMBL
NCBI Gene	ONECUT1	ENTREZGENE
PANTHER	HEPATOCYTE NUCLEAR FACTOR 6	UniProtKB/TrEMBL
	TRANSCRIPTION FACTOR ONECUT	UniProtKB/TrEMBL
Pfam	CUT	UniProtKB/TrEMBL
	Homeodomain	UniProtKB/TrEMBL
PROSITE	CUT	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
SMART	CUT	UniProtKB/TrEMBL
	HOX	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46689	UniProtKB/TrEMBL
	SSF47413	UniProtKB/TrEMBL
UniProt	A0A8C0NJ34	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0R076	ENTREZGENE
	A0A8I3PVL4	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:44123	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar