KCNJ14 (potassium inwardly rectifying channel subfamily J member 14) - Rat Genome Database

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Gene: KCNJ14 (potassium inwardly rectifying channel subfamily J member 14) Canis lupus familiaris
Analyze
Symbol: KCNJ14
Name: potassium inwardly rectifying channel subfamily J member 14
RGD ID: 12212078
Description: ENCODES a protein that exhibits inward rectifier potassium channel activity (ortholog); INVOLVED IN monoatomic cation transmembrane transport (inferred); monoatomic ion transmembrane transport (inferred); potassium ion import across plasma membrane (inferred); PARTICIPATES IN neuron-to-neuron signaling pathway via the chemical synapse; FOUND IN dendrite (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-sensitive inward rectifier potassium channel 14; potassium inwardly-rectifying channel, subfamily J, member 14; potassium voltage-gated channel subfamily J member 14
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,804,400 - 107,813,888 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,806,285 - 107,809,199 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1107,326,278 - 107,336,127 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01108,329,375 - 108,339,219 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1108,331,263 - 108,334,177 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,995,497 - 108,005,344 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,642,816 - 107,652,672 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,478,677 - 108,488,526 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KCNJ14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,804,400 - 107,813,888 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,806,285 - 107,809,199 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1107,326,278 - 107,336,127 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01108,329,375 - 108,339,219 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1108,331,263 - 108,334,177 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,995,497 - 108,005,344 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,642,816 - 107,652,672 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,478,677 - 108,488,526 (-)NCBIUU_Cfam_GSD_1.0
KCNJ14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,455,574 - 48,466,980 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1948,455,574 - 48,466,980 (+)EnsemblGRCh38hg38GRCh38
GRCh371948,958,831 - 48,970,237 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361953,650,578 - 53,661,179 (+)NCBINCBI36Build 36hg18NCBI36
Build 341953,656,317 - 53,661,179NCBI
Celera1945,824,005 - 45,834,608 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,339,157 - 45,349,560 (+)NCBIHuRef
CHM1_11948,960,783 - 48,971,187 (+)NCBICHM1_1
T2T-CHM13v2.01951,449,735 - 51,461,143 (+)NCBIT2T-CHM13v2.0
Kcnj14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,465,871 - 45,474,180 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,465,884 - 45,474,206 (-)EnsemblGRCm39 Ensembl
GRCm38745,816,467 - 45,824,747 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,816,460 - 45,824,782 (-)EnsemblGRCm38mm10GRCm38
MGSCv37753,071,837 - 53,080,117 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,684,509 - 45,692,789 (-)NCBIMGSCv36mm8
Celera741,280,615 - 41,288,895 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.53NCBI
Kcnj14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,429,607 - 105,437,258 (-)NCBIGRCr8
mRatBN7.2196,293,159 - 96,300,810 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl196,293,435 - 96,495,459 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,679,302 - 101,686,953 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01110,151,284 - 110,158,935 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,441,659 - 103,449,310 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,805,531 - 101,809,544 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,805,531 - 101,809,544 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,884,516 - 102,888,529 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,293,795 - 96,297,747 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1196,371,905 - 96,375,858 (-)NCBI
Celera190,545,941 - 90,549,958 (-)NCBICelera
Cytogenetic Map1q22NCBI
Kcnj14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555592,023,444 - 2,028,491 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555592,023,993 - 2,028,082 (-)NCBIChiLan1.0ChiLan1.0
KCNJ14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22054,559,792 - 54,574,531 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11956,486,254 - 56,500,859 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01945,456,082 - 45,469,017 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,055,580 - 54,060,204 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1954,055,580 - 54,060,204 (+)Ensemblpanpan1.1panPan2
Kcnj14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934920,937,184 - 20,946,068 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366642,556,750 - 2,563,288 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366642,555,727 - 2,564,245 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNJ14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl653,862,194 - 53,866,395 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1653,861,755 - 53,866,765 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2649,552,004 - 49,557,744 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNJ14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1641,715,293 - 41,727,017 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl641,723,429 - 41,726,451 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607321,507,807 - 21,513,506 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnj14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,346,245 - 5,349,071 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248325,344,917 - 5,349,071 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KCNJ14
125 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 1 1
Below cutoff 4 4 17 3 5 3 5 3 11 7 8 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000006406   ⟹   ENSCAFP00000005930
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1107,806,285 - 107,809,199 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845002354   ⟹   ENSCAFP00845001870
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1108,331,263 - 108,334,177 (-)Ensembl
RefSeq Acc Id: XM_014119185   ⟹   XP_013974660
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11107,804,400 - 107,813,888 (-)NCBI
Dog10K_Boxer_Tasha1107,326,278 - 107,336,127 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038467656   ⟹   XP_038323584
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11107,995,497 - 108,005,344 (-)NCBI
RefSeq Acc Id: XM_038528371   ⟹   XP_038384299
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01108,478,677 - 108,488,526 (-)NCBI
RefSeq Acc Id: XM_038592660   ⟹   XP_038448588
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01107,642,816 - 107,652,672 (-)NCBI
RefSeq Acc Id: XM_038656451   ⟹   XP_038512379
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01108,329,375 - 108,339,219 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_013974660   ⟸   XM_014119185
- UniProtKB: A0A8C0N6M7 (UniProtKB/TrEMBL),   A0A8C0R8F7 (UniProtKB/TrEMBL),   A0A8I3RRG3 (UniProtKB/TrEMBL),   A0A8C0PPS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000005930   ⟸   ENSCAFT00000006406
RefSeq Acc Id: XP_038323584   ⟸   XM_038467656
RefSeq Acc Id: XP_038448588   ⟸   XM_038592660
RefSeq Acc Id: XP_038512379   ⟸   XM_038656451
- UniProtKB: A0A8C0N6M7 (UniProtKB/TrEMBL),   A0A8C0R8F7 (UniProtKB/TrEMBL),   A0A8I3RRG3 (UniProtKB/TrEMBL),   A0A8C0PPS7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038384299   ⟸   XM_038528371
- UniProtKB: A0A8C0N6M7 (UniProtKB/TrEMBL),   A0A8C0PPS7 (UniProtKB/TrEMBL),   A0A8C0R8F7 (UniProtKB/TrEMBL),   A0A8I3RRG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845001870   ⟸   ENSCAFT00845002354
Protein Domains
Inward rectifier potassium channel C-terminal   Potassium channel inwardly rectifying transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004001 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030011871 UniProtKB/TrEMBL
  ENSCAFG00040001384 UniProtKB/TrEMBL
  ENSCAFG00845001375 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000006406.6 UniProtKB/TrEMBL
  ENSCAFT00030021971.1 UniProtKB/TrEMBL
  ENSCAFT00040002617.1 UniProtKB/TrEMBL
  ENSCAFT00845002354 ENTREZGENE
  ENSCAFT00845002354.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  2.60.40.1400 UniProtKB/TrEMBL
InterPro Ig_E-set UniProtKB/TrEMBL
  IRK_C UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir_cyto UniProtKB/TrEMBL
  Kir_TM UniProtKB/TrEMBL
KEGG Report cfa:612053 UniProtKB/TrEMBL
NCBI Gene KCNJ14 ENTREZGENE
PANTHER ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 14 UniProtKB/TrEMBL
  PTHR11767 UniProtKB/TrEMBL
Pfam IRK UniProtKB/TrEMBL
  IRK_C UniProtKB/TrEMBL
PIRSF GIRK_kir UniProtKB/TrEMBL
PRINTS KIRCHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF81296 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A8C0N6M7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PPS7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0R8F7 ENTREZGENE
  A0A8I3RRG3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:111538 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-23 KCNJ14  potassium inwardly rectifying channel subfamily J member 14  KCNJ14  potassium voltage-gated channel subfamily J member 14  Symbol and/or name change 5135510 APPROVED