H1-1 (H1.1 linker histone, cluster member) - Rat Genome Database

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Gene: H1-1 (H1.1 linker histone, cluster member) Canis lupus familiaris
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Symbol: H1-1
Name: H1.1 linker histone, cluster member
RGD ID: 12158480
Description: ENCODES a protein that exhibits chromatin DNA binding (ortholog); heparin binding (ortholog); INVOLVED IN positive regulation of receptor-mediated endocytosis (ortholog); spermatogenesis (ortholog); FOUND IN cell surface (ortholog); chromatin (ortholog); euchromatin (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone H1.1; LOC488258
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13523,973,893 - 23,974,739 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3523,844,635 - 23,853,151 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03524,081,162 - 24,089,678 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3524,088,968 - 24,089,615 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13523,897,517 - 23,906,023 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03523,950,255 - 23,957,087 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03525,381,155 - 25,389,674 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell surface  (ISO)
chromatin  (ISO)
chromosome  (IEA)
euchromatin  (ISO)
nucleoplasm  (ISO)
nucleosome  (IEA)
nucleus  (IEA)
vesicle  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202   PMID:37756605  


Genomics

Comparative Map Data
H1-1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13523,973,893 - 23,974,739 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3523,844,635 - 23,853,151 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03524,081,162 - 24,089,678 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3524,088,968 - 24,089,615 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13523,897,517 - 23,906,023 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03523,950,255 - 23,957,087 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03525,381,155 - 25,389,674 (-)NCBIUU_Cfam_GSD_1.0
H1-1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38626,017,032 - 26,017,787 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl626,017,032 - 26,017,787 (-)EnsemblGRCh38hg38GRCh38
GRCh37626,017,260 - 26,018,015 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36626,125,239 - 26,126,019 (-)NCBINCBI36Build 36hg18NCBI36
Build 34626,125,238 - 26,125,995NCBI
Celera627,244,484 - 27,245,264 (-)NCBICelera
Cytogenetic Map6p22.2NCBI
HuRef625,960,326 - 25,961,106 (-)NCBIHuRef
CHM1_1626,019,536 - 26,020,316 (-)NCBICHM1_1
T2T-CHM13v2.0625,882,972 - 25,883,727 (-)NCBIT2T-CHM13v2.0
H1f1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391323,947,651 - 23,948,395 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1323,947,649 - 23,948,389 (+)EnsemblGRCm39 Ensembl
GRCm381323,763,668 - 23,764,412 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1323,763,666 - 23,764,406 (+)EnsemblGRCm38mm10GRCm38
MGSCv371323,855,537 - 23,856,283 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361323,771,133 - 23,771,879 (+)NCBIMGSCv36mm8
Celera1323,995,434 - 23,996,176 (+)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map139.91NCBI
H1f1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81741,762,278 - 41,794,876 (-)NCBIGRCr8
mRatBN7.21741,366,268 - 41,367,011 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1741,366,268 - 41,367,011 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1741,440,327 - 41,441,067 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01743,044,373 - 43,045,113 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01741,323,040 - 41,323,783 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01743,614,101 - 43,614,844 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1743,614,101 - 43,614,844 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01745,468,486 - 45,469,229 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41748,526,427 - 48,527,170 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11748,529,313 - 48,530,006 (+)NCBI
Celera1740,997,741 - 40,998,484 (-)NCBICelera
Cytogenetic Map17p11NCBI
H1-1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955483996,019 - 1,008,034 (+)NCBIChiLan1.0ChiLan1.0
H1-1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2540,660,272 - 40,666,076 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1636,664,358 - 36,665,112 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0625,850,443 - 25,851,223 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1626,508,422 - 26,509,202 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl626,508,481 - 26,509,128 (-)Ensemblpanpan1.1panPan2
H1-1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049461,743,534 - 1,745,376 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366711,877,303 - 1,877,959 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366711,876,497 - 1,878,006 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
H1-1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1720,717,123 - 20,717,916 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
H1-1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11746,235,596 - 46,239,777 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1746,237,985 - 46,238,629 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604425,952,657 - 25,953,597 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
H1-1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624756885,994 - 886,641 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624756885,994 - 901,354 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in H1-1
15 total Variants

Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCAFT00845044805   ⟹   ENSCAFP00845035112
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3524,088,968 - 24,089,615 (-)Ensembl
RefSeq Acc Id: XM_038446539   ⟹   XP_038302467
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03524,081,162 - 24,089,678 (-)NCBI
RefSeq Acc Id: XM_038520668   ⟹   XP_038376596
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13523,897,517 - 23,906,023 (-)NCBI
RefSeq Acc Id: XM_038584340   ⟹   XP_038440268
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03525,381,155 - 25,389,674 (-)NCBI
RefSeq Acc Id: XM_038648770   ⟹   XP_038504698
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03523,950,255 - 23,957,087 (-)NCBI
RefSeq Acc Id: XM_545380   ⟹   XP_545380
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13523,973,893 - 23,974,739 (-)NCBI
Dog10K_Boxer_Tasha3523,844,635 - 23,853,151 (-)NCBI
Sequence:
RefSeq Acc Id: XP_545380   ⟸   XM_545380
- UniProtKB: A0A8I3Q6R5 (UniProtKB/TrEMBL),   A0A8P0PNW4 (UniProtKB/TrEMBL),   A0A8C0K7I7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038376596   ⟸   XM_038520668
RefSeq Acc Id: XP_038504698   ⟸   XM_038648770
RefSeq Acc Id: XP_038302467   ⟸   XM_038446539
- UniProtKB: A0A8I3Q6R5 (UniProtKB/TrEMBL),   A0A8P0PNW4 (UniProtKB/TrEMBL),   A0A8C0K7I7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038440268   ⟸   XM_038584340
- UniProtKB: A0A8C0K7I7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845035112   ⟸   ENSCAFT00845044805
Protein Domains
H15


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000057465 UniProtKB/TrEMBL
  ENSCAFG00845025396 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000102773.1 UniProtKB/TrEMBL
  ENSCAFT00845044805 ENTREZGENE
  ENSCAFT00845044805.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro H1/H5 UniProtKB/TrEMBL
  Histone_H1/H5_H15 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report cfa:488258 UniProtKB/TrEMBL
NCBI Gene LOC488258 ENTREZGENE
PANTHER HISTONE H1 UniProtKB/TrEMBL
  HISTONE H1.1 UniProtKB/TrEMBL
Pfam Linker_histone UniProtKB/TrEMBL
PRINTS HISTONEH5 UniProtKB/TrEMBL
PROSITE H15 UniProtKB/TrEMBL
SMART H15 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt A0A8C0K7I7 ENTREZGENE
  A0A8I3Q6R5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PNW4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:83712 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-30 H1-1  H1.1 linker histone, cluster member  LOC488258  histone H1.1  Symbol and/or name change 5135510 APPROVED