SLC23A2 (solute carrier family 23 member 2) - Rat Genome Database

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Gene: SLC23A2 (solute carrier family 23 member 2) Canis lupus familiaris
Analyze
Symbol: SLC23A2
Name: solute carrier family 23 member 2
RGD ID: 12156508
Description: ENCODES a protein that exhibits L-ascorbate:sodium symporter activity (ortholog); INVOLVED IN blood circulation (ortholog); cellular response to ethanol (ortholog); L-ascorbic acid metabolic process (ortholog); ASSOCIATED WITH Binge Drinking (ortholog); cholestasis (ortholog); Huntington's disease-like 1 (ortholog); FOUND IN apical plasma membrane (inferred); basal plasma membrane (inferred); basolateral plasma membrane (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: sodium-dependent vitamin C transporter-2; solute carrier family 23 (nucleobase transporters), member 1; solute carrier family 23 (nucleobase transporters), member 2; SVCT2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12416,573,616 - 16,709,296 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2416,574,168 - 16,709,296 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2416,425,818 - 16,531,856 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02416,981,643 - 17,127,359 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2416,990,701 - 17,127,359 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12416,613,514 - 16,719,979 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02416,720,357 - 16,826,526 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02417,054,182 - 17,160,266 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:15993839   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC23A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12416,573,616 - 16,709,296 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2416,574,168 - 16,709,296 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2416,425,818 - 16,531,856 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02416,981,643 - 17,127,359 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2416,990,701 - 17,127,359 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12416,613,514 - 16,719,979 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02416,720,357 - 16,826,526 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02417,054,182 - 17,160,266 (+)NCBIUU_Cfam_GSD_1.0
SLC23A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38204,852,358 - 5,010,313 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl204,852,356 - 5,010,293 (-)EnsemblGRCh38hg38GRCh38
GRCh37204,833,004 - 4,990,959 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36204,781,002 - 4,938,939 (-)NCBINCBI36Build 36hg18NCBI36
Build 34204,781,001 - 4,938,939NCBI
Celera204,902,706 - 5,051,861 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef204,787,194 - 4,944,817 (-)NCBIHuRef
CHM1_1204,834,496 - 4,992,439 (-)NCBICHM1_1
T2T-CHM13v2.0204,891,820 - 5,049,741 (-)NCBIT2T-CHM13v2.0
Slc23a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392131,894,416 - 131,987,287 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2131,894,416 - 131,987,028 (-)EnsemblGRCm39 Ensembl
GRCm382132,052,496 - 132,145,320 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2132,052,496 - 132,145,108 (-)EnsemblGRCm38mm10GRCm38
MGSCv372131,878,232 - 131,970,844 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362131,743,937 - 131,836,549 (-)NCBIMGSCv36mm8
Celera2133,279,011 - 133,328,217 (-)NCBICelera
Cytogenetic Map2F2NCBI
cM Map264.15NCBI
Slc23a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83139,755,583 - 139,913,304 (-)NCBIGRCr8
mRatBN7.23119,302,651 - 119,395,289 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3119,302,666 - 119,460,343 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3123,206,656 - 123,298,423 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03131,793,663 - 131,885,649 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03129,462,752 - 129,554,530 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03124,632,491 - 124,842,225 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3124,632,492 - 124,724,252 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03131,132,124 - 131,266,028 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43119,796,376 - 119,886,011 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13119,701,948 - 119,791,584 (-)NCBI
Celera3118,102,047 - 118,150,099 (-)NCBICelera
Cytogenetic Map3q36NCBI
Slc23a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541515,565,249 - 15,642,153 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541515,565,344 - 15,677,935 (-)NCBIChiLan1.0ChiLan1.0
SLC23A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2215,801,682 - 6,017,566 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1205,798,507 - 6,014,383 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0204,874,185 - 5,024,750 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1204,670,294 - 4,790,800 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl204,670,294 - 4,790,800 (-)Ensemblpanpan1.1panPan2
Slc23a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640165,431,608 - 165,545,259 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648513,885,091 - 13,976,550 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648513,885,067 - 13,976,623 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC23A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1713,848,728 - 14,011,700 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11713,848,726 - 14,012,054 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21714,819,223 - 14,825,302 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC23A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1233,092,619 - 33,209,258 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl233,128,061 - 33,212,255 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607111,323,229 - 11,470,263 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc23a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247415,917,019 - 6,000,720 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247415,917,620 - 6,050,922 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC23A2
1359 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001109956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001313813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005634670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005634671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005634672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014106831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022408806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022408807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038432789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038432790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY264779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU125350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000009756
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2416,603,479 - 16,708,832 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000047756
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2416,574,168 - 16,704,836 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000066378
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2416,650,515 - 16,709,296 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000087936
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2416,603,479 - 16,709,296 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000088580
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2416,574,168 - 16,604,398 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000090169
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2416,647,594 - 16,709,296 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845050456   ⟹   ENSCAFP00845039561
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2416,990,701 - 17,127,036 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845050552   ⟹   ENSCAFP00845039634
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2417,021,203 - 17,123,077 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845050583   ⟹   ENSCAFP00845039658
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2417,021,206 - 17,123,023 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845050918   ⟹   ENSCAFP00845039917
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2417,065,639 - 17,127,359 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845050952   ⟹   ENSCAFP00845039944
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2417,068,566 - 17,127,359 (+)Ensembl
RefSeq Acc Id: NM_001109956   ⟹   NP_001103426
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12416,647,594 - 16,709,296 (+)NCBI
Dog10K_Boxer_Tasha2416,470,183 - 16,531,856 (+)NCBI
ROS_Cfam_1.02417,065,639 - 17,127,359 (+)NCBI
UMICH_Zoey_3.12416,658,306 - 16,719,979 (+)NCBI
UNSW_CanFamBas_1.02416,764,858 - 16,826,526 (+)NCBI
UU_Cfam_GSD_1.02417,098,583 - 17,160,266 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001313813   ⟹   NP_001300742
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12416,603,479 - 16,709,296 (+)NCBI
Dog10K_Boxer_Tasha2416,425,818 - 16,531,856 (+)NCBI
ROS_Cfam_1.02417,021,262 - 17,127,359 (+)NCBI
UMICH_Zoey_3.12416,613,514 - 16,719,979 (+)NCBI
UNSW_CanFamBas_1.02416,720,357 - 16,826,526 (+)NCBI
UU_Cfam_GSD_1.02417,054,182 - 17,160,266 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038432789   ⟹   XP_038288717
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02416,981,643 - 17,127,357 (+)NCBI
RefSeq Acc Id: XM_038432790   ⟹   XP_038288718
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02417,035,639 - 17,127,357 (+)NCBI
RefSeq Acc Id: NP_001300742   ⟸   NM_001313813
- Peptide Label: isoform 1
- UniProtKB: A0A8C0JJ97 (UniProtKB/TrEMBL),   A0A8C0QMP7 (UniProtKB/TrEMBL),   A0A8I3PXN1 (UniProtKB/TrEMBL),   A0A8I3PXI5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103426   ⟸   NM_001109956
- Peptide Label: isoform 2
- UniProtKB: A0A8C0S0V7 (UniProtKB/TrEMBL),   A0A8I3S6V8 (UniProtKB/TrEMBL),   A8CWZ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038288717   ⟸   XM_038432789
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JJ97 (UniProtKB/TrEMBL),   A0A8C0QMP7 (UniProtKB/TrEMBL),   A0A8I3PXN1 (UniProtKB/TrEMBL),   A0A8I3PXI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038288718   ⟸   XM_038432790
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JJ97 (UniProtKB/TrEMBL),   A0A8C0QMP7 (UniProtKB/TrEMBL),   A0A8I3PXN1 (UniProtKB/TrEMBL),   A0A8I3PXI5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845039658   ⟸   ENSCAFT00845050583
Ensembl Acc Id: ENSCAFP00845039944   ⟸   ENSCAFT00845050952
Ensembl Acc Id: ENSCAFP00845039561   ⟸   ENSCAFT00845050456
Ensembl Acc Id: ENSCAFP00845039917   ⟸   ENSCAFT00845050918
Ensembl Acc Id: ENSCAFP00845039634   ⟸   ENSCAFT00845050552

Promoters
RGD ID:13687528
Promoter ID:EPDNEW_C5596
Type:multiple initiation site
Name:SLC23A2_1
Description:solute carrier family 23 member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12416,574,232 - 16,574,292EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006042 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030021974 UniProtKB/TrEMBL
  ENSCAFG00040008490 UniProtKB/TrEMBL
  ENSCAFG00845028487 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000009756.5 UniProtKB/TrEMBL
  ENSCAFT00000066378.2 UniProtKB/TrEMBL
  ENSCAFT00000087936.2 UniProtKB/TrEMBL
  ENSCAFT00000090169.2 UniProtKB/TrEMBL
  ENSCAFT00030040503.1 UniProtKB/TrEMBL
  ENSCAFT00030040603.1 UniProtKB/TrEMBL
  ENSCAFT00030040694.1 UniProtKB/TrEMBL
  ENSCAFT00030040742.1 UniProtKB/TrEMBL
  ENSCAFT00030040761.1 UniProtKB/TrEMBL
  ENSCAFT00040016101.1 UniProtKB/TrEMBL
  ENSCAFT00040016204.1 UniProtKB/TrEMBL
  ENSCAFT00040016319.1 UniProtKB/TrEMBL
  ENSCAFT00040016357.1 UniProtKB/TrEMBL
  ENSCAFT00845050456 ENTREZGENE
  ENSCAFT00845050456.1 UniProtKB/TrEMBL
  ENSCAFT00845050552.1 UniProtKB/TrEMBL
  ENSCAFT00845050583 ENTREZGENE
  ENSCAFT00845050583.1 UniProtKB/TrEMBL
  ENSCAFT00845050918 ENTREZGENE
  ENSCAFT00845050918.1 UniProtKB/TrEMBL
  ENSCAFT00845050952.1 UniProtKB/TrEMBL
InterPro NCS2 UniProtKB/TrEMBL
  Xan_ur_permease UniProtKB/TrEMBL
NCBI Gene SLC23A2 ENTREZGENE
PANTHER PTHR11119:SF33 UniProtKB/TrEMBL
  XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER UniProtKB/TrEMBL
Pfam Xan_ur_permease UniProtKB/TrEMBL
PROSITE XANTH_URACIL_PERMASE UniProtKB/TrEMBL
UniProt A0A8C0JJ97 ENTREZGENE
  A0A8C0P3M7_CANLF UniProtKB/TrEMBL
  A0A8C0P6A1_CANLF UniProtKB/TrEMBL
  A0A8C0PEB1_CANLF UniProtKB/TrEMBL
  A0A8C0QMP7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0S0V7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PX93_CANLF UniProtKB/TrEMBL
  A0A8I3PXI5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PXN1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q5F2_CANLF UniProtKB/TrEMBL
  A0A8I3S6V8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PQM7_CANLF UniProtKB/TrEMBL
  A8CWZ7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:46283 ENTREZGENE