MIR302B (microRNA mir-302b) - Rat Genome Database

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Gene: MIR302B (microRNA mir-302b) Canis lupus familiaris
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Symbol: MIR302B (Ensembl: cfa-mir-302b)
Name: microRNA mir-302b (Ensembl:cfa-mir-302b)
RGD ID: 12151647
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: cfa-mir-302b; microRNA 302b
RGD Orthologs
Human
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13232,429,500 - 32,429,574 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3232,429,500 - 32,429,574 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha329,602,175 - 9,602,249 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03232,655,305 - 32,655,379 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13232,637,985 - 32,638,059 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03232,399,917 - 32,399,991 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0327,460,618 - 7,460,692 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MIR302BDoganiridia  ISOMIR302B (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital aniridiaClinVar 
MIR302BDogAxenfeld-Rieger syndrome type 1  ISOMIR302B (Homo sapiens)8554872ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 1ClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MIR302BDogosteosarcoma  ISOMIR302B (Homo sapiens)9068941CTD Direct Evidence: therapeuticCTDPMID:23845851


Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MIR302BDogRISC complex part_ofIEARfam:RF00668150520179 RNAcentralGO_REF:0000115

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MIR302BDogmRNA base-pairing translational repressor activity enablesISOMIR302B (Homo sapiens)9068941 PMID:21490602BHF-UCLPMID:21490602

PMID:16381832   PMID:18215311  



MIR302B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13232,429,500 - 32,429,574 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3232,429,500 - 32,429,574 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha329,602,175 - 9,602,249 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03232,655,305 - 32,655,379 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13232,637,985 - 32,638,059 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03232,399,917 - 32,399,991 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0327,460,618 - 7,460,692 (+)NCBIUU_Cfam_GSD_1.0
MIR302B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384112,648,485 - 112,648,557 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4112,648,485 - 112,648,557 (-)EnsemblGRCh38hg38GRCh38
GRCh374113,569,641 - 113,569,713 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364113,789,089 - 113,789,161 (-)NCBINCBI36Build 36hg18NCBI36
Celera4110,863,734 - 110,863,806 (-)NCBICelera
Cytogenetic Map4q25NCBI
HuRef4109,298,061 - 109,298,133 (-)NCBIHuRef
CHM1_14113,546,133 - 113,546,205 (-)NCBICHM1_1
T2T-CHM13v2.04115,956,825 - 115,956,897 (-)NCBIT2T-CHM13v2.0
Mir302b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393127,338,877 - 127,338,950 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3127,338,877 - 127,338,950 (+)EnsemblGRCm39 Ensembl
GRCm383127,545,228 - 127,545,301 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3127,545,228 - 127,545,301 (+)EnsemblGRCm38mm10GRCm38
MGSCv373127,248,146 - 127,248,219 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera3134,034,776 - 134,034,849 (+)NCBICelera
Cytogenetic Map3G2NCBI
cM Map356.54NCBI

.



circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
1 13 9 1 1 1 1 1 5 4 10 7



Ensembl Acc Id: ENSCAFT00000035077
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3232,429,500 - 32,429,574 (-)Ensembl
RefSeq Acc Id: NR_049444
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13232,429,500 - 32,429,574 (-)NCBI
Dog10K_Boxer_Tasha329,602,175 - 9,602,249 (+)NCBI
ROS_Cfam_1.03232,655,305 - 32,655,379 (-)NCBI
UMICH_Zoey_3.13232,637,985 - 32,638,059 (-)NCBI
UNSW_CanFamBas_1.03232,399,917 - 32,399,991 (-)NCBI
UU_Cfam_GSD_1.0327,460,618 - 7,460,692 (+)NCBI
Sequence:


Database
Acc Id
Source(s)
Ensembl Genes ENSCAFG00000022976 Ensembl
  ENSCAFG00845017356 ENTREZGENE
Ensembl Transcript ENSCAFT00845030735 ENTREZGENE
miRBase MI0010351 ENTREZGENE
NCBI Gene MIR302B ENTREZGENE
RNAcentral URS00007E49BF RNACentral
  URS00007E4C02 RNACentral


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR302B  microRNA mir-302b    microRNA 302b  Symbol and/or name change 5135510 APPROVED