RCN2 (reticulocalbin 2) - Rat Genome Database

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Gene: RCN2 (reticulocalbin 2) Canis lupus familiaris
Analyze
Symbol: RCN2
Name: reticulocalbin 2
RGD ID: 12145529
Description: ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN endoplasmic reticulum (inferred); nucleolus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: reticulocalbin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13039,341,593 - 39,356,899 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3039,342,107 - 39,357,433 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3039,202,331 - 39,217,625 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03039,544,448 - 39,559,744 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3039,528,899 - 39,559,761 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13039,492,429 - 39,507,723 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03039,540,997 - 39,556,294 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03039,778,402 - 39,793,607 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RCN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13039,341,593 - 39,356,899 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3039,342,107 - 39,357,433 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3039,202,331 - 39,217,625 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03039,544,448 - 39,559,744 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3039,528,899 - 39,559,761 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13039,492,429 - 39,507,723 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03039,540,997 - 39,556,294 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03039,778,402 - 39,793,607 (-)NCBIUU_Cfam_GSD_1.0
RCN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381576,931,749 - 76,954,393 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1576,931,738 - 76,954,393 (+)EnsemblGRCh38hg38GRCh38
GRCh371577,224,090 - 77,246,734 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361575,011,171 - 75,029,302 (+)NCBINCBI36Build 36hg18NCBI36
Build 341575,011,170 - 75,029,300NCBI
Celera1554,155,320 - 54,173,958 (+)NCBICelera
Cytogenetic Map15q24.3NCBI
HuRef1553,980,879 - 53,999,495 (+)NCBIHuRef
CHM1_11577,342,151 - 77,360,793 (+)NCBICHM1_1
T2T-CHM13v2.01574,790,799 - 74,813,427 (+)NCBIT2T-CHM13v2.0
Rcn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39955,949,129 - 55,966,367 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl955,949,129 - 55,969,166 (+)EnsemblGRCm39 Ensembl
GRCm38956,041,845 - 56,059,083 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl956,041,845 - 56,061,882 (+)EnsemblGRCm38mm10GRCm38
MGSCv37955,889,652 - 55,906,890 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36955,839,997 - 55,856,978 (+)NCBIMGSCv36mm8
Celera953,267,260 - 53,284,837 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map930.13NCBI
Rcn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8865,345,247 - 65,362,290 (+)NCBIGRCr8
mRatBN7.2856,449,206 - 56,466,253 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl856,449,206 - 56,466,251 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx861,967,663 - 61,984,886 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0860,246,674 - 60,263,897 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0858,110,919 - 58,128,142 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0860,709,851 - 60,726,938 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl860,709,851 - 60,726,936 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0859,280,449 - 59,297,536 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4859,642,818 - 59,659,854 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1859,661,893 - 59,678,908 (+)NCBI
Celera855,922,137 - 55,939,180 (+)NCBICelera
Cytogenetic Map8q24NCBI
Rcn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554501,838,734 - 1,857,254 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554501,838,836 - 1,854,045 (+)NCBIChiLan1.0ChiLan1.0
RCN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21666,138,146 - 66,160,334 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11570,302,594 - 70,324,783 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01555,857,130 - 55,875,365 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11575,445,908 - 75,463,947 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1575,445,908 - 75,463,947 (+)Ensemblpanpan1.1panPan2
Rcn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640117,499,911 - 117,516,446 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647135,347,298 - 35,364,772 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647135,347,775 - 35,364,512 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RCN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl757,041,003 - 57,059,330 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1757,040,872 - 57,058,277 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2761,775,705 - 61,793,113 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RCN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1266,348,032 - 6,366,302 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl266,347,539 - 6,366,122 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048135,374,115 - 135,392,273 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rcn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248941,429,107 - 1,450,515 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248941,431,375 - 1,450,156 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RCN2
181 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000028726   ⟹   ENSCAFP00000026719
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3039,342,107 - 39,357,239 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000061453   ⟹   ENSCAFP00000062976
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3039,342,107 - 39,357,433 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000083717   ⟹   ENSCAFP00000052242
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3039,342,107 - 39,356,780 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845040099   ⟹   ENSCAFP00845031400
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3039,528,899 - 39,559,761 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845040200   ⟹   ENSCAFP00845031486
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3039,544,449 - 39,559,636 (-)Ensembl
RefSeq Acc Id: XM_005638659   ⟹   XP_005638716
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13039,341,593 - 39,356,899 (-)NCBI
Dog10K_Boxer_Tasha3039,202,331 - 39,217,625 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038443074   ⟹   XP_038299002
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03039,544,448 - 39,559,744 (-)NCBI
RefSeq Acc Id: XM_038443075   ⟹   XP_038299003
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03039,544,448 - 39,559,744 (-)NCBI
RefSeq Acc Id: XM_038517504   ⟹   XP_038373432
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13039,492,429 - 39,507,723 (-)NCBI
RefSeq Acc Id: XM_038517505   ⟹   XP_038373433
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13039,492,429 - 39,507,723 (-)NCBI
RefSeq Acc Id: XM_038581072   ⟹   XP_038437000
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03039,778,402 - 39,793,607 (-)NCBI
RefSeq Acc Id: XM_038645437   ⟹   XP_038501365
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03039,540,997 - 39,556,294 (-)NCBI
RefSeq Acc Id: XM_038645438   ⟹   XP_038501366
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03039,540,997 - 39,556,294 (-)NCBI
RefSeq Acc Id: XM_544790   ⟹   XP_544790
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13039,341,593 - 39,356,898 (-)NCBI
Dog10K_Boxer_Tasha3039,202,331 - 39,217,625 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005638716   ⟸   XM_005638659
- Peptide Label: isoform X2
- UniProtKB: A0A8I3PKT1 (UniProtKB/TrEMBL),   A0A8P0NJK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_544790   ⟸   XM_544790
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JSE3 (UniProtKB/TrEMBL),   A0A8C0MKF8 (UniProtKB/TrEMBL),   A0A8P0TEN6 (UniProtKB/TrEMBL),   A0A8P0NJK3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000026719   ⟸   ENSCAFT00000028726
Ensembl Acc Id: ENSCAFP00000052242   ⟸   ENSCAFT00000083717
Ensembl Acc Id: ENSCAFP00000062976   ⟸   ENSCAFT00000061453
RefSeq Acc Id: XP_038373433   ⟸   XM_038517505
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038373432   ⟸   XM_038517504
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038501366   ⟸   XM_038645438
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038501365   ⟸   XM_038645437
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038299003   ⟸   XM_038443075
- Peptide Label: isoform X2
- UniProtKB: A0A8I3PKT1 (UniProtKB/TrEMBL),   A0A8P0NJK3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038299002   ⟸   XM_038443074
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JSE3 (UniProtKB/TrEMBL),   A0A8C0MKF8 (UniProtKB/TrEMBL),   A0A8P0TEN6 (UniProtKB/TrEMBL),   A0A8P0NJK3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038437000   ⟸   XM_038581072
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JSE3 (UniProtKB/TrEMBL),   A0A8C0MKF8 (UniProtKB/TrEMBL),   A0A8P0NJK3 (UniProtKB/TrEMBL),   A0A8P0TEN6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845031400   ⟸   ENSCAFT00845040099
Ensembl Acc Id: ENSCAFP00845031486   ⟸   ENSCAFT00845040200
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018077 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030006970 UniProtKB/TrEMBL
  ENSCAFG00040019300 UniProtKB/TrEMBL
  ENSCAFG00845022713 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000028726.5 UniProtKB/TrEMBL
  ENSCAFT00000061453.2 UniProtKB/TrEMBL
  ENSCAFT00000083717.2 UniProtKB/TrEMBL
  ENSCAFT00030012885.1 UniProtKB/TrEMBL
  ENSCAFT00030012930.1 UniProtKB/TrEMBL
  ENSCAFT00040035787.1 UniProtKB/TrEMBL
  ENSCAFT00845040099 ENTREZGENE
  ENSCAFT00845040099.1 UniProtKB/TrEMBL
  ENSCAFT00845040200.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
NCBI Gene RCN2 ENTREZGENE
PANTHER RETICULOCALBIN UniProtKB/TrEMBL
  RETICULOCALBIN-2 UniProtKB/TrEMBL
Pfam EF-hand_5 UniProtKB/TrEMBL
  EF-hand_7 UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A8C0JSE3 ENTREZGENE
  A0A8C0MKF8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MMK0_CANLF UniProtKB/TrEMBL
  A0A8I3PJS1_CANLF UniProtKB/TrEMBL
  A0A8I3PKT1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NJK3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TEN6 ENTREZGENE
UniProt Secondary A0A8P0TEN6 UniProtKB/TrEMBL
VGNC ID VGNC:54349 ENTREZGENE