RCN2 (reticulocalbin 2) - Rat Genome Database

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Gene: RCN2 (reticulocalbin 2) Sus scrofa
Analyze
Symbol: RCN2
Name: reticulocalbin 2
RGD ID: 13957734
Description: ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN endoplasmic reticulum (inferred); nucleolus (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: reticulocalbin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl757,041,003 - 57,059,330 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1757,040,872 - 57,058,277 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2761,775,705 - 61,793,113 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:17407547   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RCN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl757,041,003 - 57,059,330 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1757,040,872 - 57,058,277 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2761,775,705 - 61,793,113 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RCN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381576,931,749 - 76,954,393 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1576,931,738 - 76,954,393 (+)EnsemblGRCh38hg38GRCh38
GRCh371577,224,090 - 77,246,734 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361575,011,171 - 75,029,302 (+)NCBINCBI36Build 36hg18NCBI36
Build 341575,011,170 - 75,029,300NCBI
Celera1554,155,320 - 54,173,958 (+)NCBICelera
Cytogenetic Map15q24.3NCBI
HuRef1553,980,879 - 53,999,495 (+)NCBIHuRef
CHM1_11577,342,151 - 77,360,793 (+)NCBICHM1_1
T2T-CHM13v2.01574,790,799 - 74,813,427 (+)NCBIT2T-CHM13v2.0
Rcn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39955,949,129 - 55,966,367 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl955,949,129 - 55,969,166 (+)EnsemblGRCm39 Ensembl
GRCm38956,041,845 - 56,059,083 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl956,041,845 - 56,061,882 (+)EnsemblGRCm38mm10GRCm38
MGSCv37955,889,652 - 55,906,890 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36955,839,997 - 55,856,978 (+)NCBIMGSCv36mm8
Celera953,267,260 - 53,284,837 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map930.13NCBI
Rcn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8865,345,247 - 65,362,290 (+)NCBIGRCr8
mRatBN7.2856,449,206 - 56,466,253 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl856,449,206 - 56,466,251 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx861,967,663 - 61,984,886 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0860,246,674 - 60,263,897 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0858,110,919 - 58,128,142 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0860,709,851 - 60,726,938 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl860,709,851 - 60,726,936 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0859,280,449 - 59,297,536 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4859,642,818 - 59,659,854 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1859,661,893 - 59,678,908 (+)NCBI
Celera855,922,137 - 55,939,180 (+)NCBICelera
Cytogenetic Map8q24NCBI
Rcn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554501,838,734 - 1,857,254 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554501,838,836 - 1,854,045 (+)NCBIChiLan1.0ChiLan1.0
RCN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21666,138,146 - 66,160,334 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11570,302,594 - 70,324,783 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01555,857,130 - 55,875,365 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11575,445,908 - 75,463,947 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1575,445,908 - 75,463,947 (+)Ensemblpanpan1.1panPan2
RCN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13039,341,593 - 39,356,899 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3039,342,107 - 39,357,433 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3039,202,331 - 39,217,625 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03039,544,448 - 39,559,744 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3039,528,899 - 39,559,761 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13039,492,429 - 39,507,723 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03039,540,997 - 39,556,294 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03039,778,402 - 39,793,607 (-)NCBIUU_Cfam_GSD_1.0
Rcn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640117,499,911 - 117,516,446 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647135,347,298 - 35,364,772 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647135,347,775 - 35,364,512 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RCN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1266,348,032 - 6,366,302 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl266,347,539 - 6,366,122 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048135,374,115 - 135,392,273 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rcn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248941,429,107 - 1,450,515 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248941,431,375 - 1,450,156 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RCN2
337 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 4 3 5 2 23 2 3 3
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001244184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005656282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005656283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021098025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK234294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK234464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK391063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK392239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP142351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT868718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT868728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EW299246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FS668414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FS670323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01072073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000002091   ⟹   ENSSSCP00000002041
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl757,041,003 - 57,059,330 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000080275   ⟹   ENSSSCP00000069038
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl757,041,077 - 57,058,276 (+)Ensembl
RefSeq Acc Id: NM_001244184   ⟹   NP_001231113
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1757,040,876 - 57,058,277 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005656282   ⟹   XP_005656339
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1757,040,881 - 57,058,277 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005656283   ⟹   XP_005656340
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1757,040,882 - 57,058,277 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021098025   ⟹   XP_020953684
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1757,040,872 - 57,058,277 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020953684   ⟸   XM_021098025
- Peptide Label: isoform X3
- UniProtKB: A0A8D0KC31 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001231113   ⟸   NM_001244184
- Peptide Label: precursor
- UniProtKB: A0A4X1TWE4 (UniProtKB/TrEMBL),   A0A8D0KC31 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005656339   ⟸   XM_005656282
- Peptide Label: isoform X1
- UniProtKB: A0A8D1NG46 (UniProtKB/TrEMBL),   F1SJ93 (UniProtKB/TrEMBL),   A0A8D0KC31 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005656340   ⟸   XM_005656283
- Peptide Label: isoform X2
- UniProtKB: A0A8D0KC31 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000002041   ⟸   ENSSSCT00000002091
RefSeq Acc Id: ENSSSCP00000069038   ⟸   ENSSSCT00000080275
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000001866 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005038228 UniProtKB/TrEMBL
  ENSSSCG00015020502 UniProtKB/TrEMBL
  ENSSSCG00025028005 UniProtKB/TrEMBL
  ENSSSCG00030063691 UniProtKB/TrEMBL
  ENSSSCG00035016179 UniProtKB/TrEMBL
  ENSSSCG00040052330 UniProtKB/TrEMBL
  ENSSSCG00045038398 UniProtKB/TrEMBL
  ENSSSCG00050063084 UniProtKB/TrEMBL
  ENSSSCG00055025626 UniProtKB/TrEMBL
  ENSSSCG00060017019 UniProtKB/TrEMBL
  ENSSSCG00065029229 UniProtKB/TrEMBL
  ENSSSCG00070012233 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000002091 ENTREZGENE
  ENSSSCT00000002091.5 UniProtKB/TrEMBL
  ENSSSCT00000080275.1 UniProtKB/TrEMBL
  ENSSSCT00005061273.1 UniProtKB/TrEMBL
  ENSSSCT00015027168.1 UniProtKB/TrEMBL
  ENSSSCT00015027298.1 UniProtKB/TrEMBL
  ENSSSCT00025038013.1 UniProtKB/TrEMBL
  ENSSSCT00025038077.1 UniProtKB/TrEMBL
  ENSSSCT00030089135.1 UniProtKB/TrEMBL
  ENSSSCT00030089187.1 UniProtKB/TrEMBL
  ENSSSCT00035020651.1 UniProtKB/TrEMBL
  ENSSSCT00035020657.1 UniProtKB/TrEMBL
  ENSSSCT00040070777.1 UniProtKB/TrEMBL
  ENSSSCT00040070881.1 UniProtKB/TrEMBL
  ENSSSCT00045066605.1 UniProtKB/TrEMBL
  ENSSSCT00045066634.1 UniProtKB/TrEMBL
  ENSSSCT00050085912.1 UniProtKB/TrEMBL
  ENSSSCT00050085920.1 UniProtKB/TrEMBL
  ENSSSCT00055051004.1 UniProtKB/TrEMBL
  ENSSSCT00055051076.1 UniProtKB/TrEMBL
  ENSSSCT00060022737.1 UniProtKB/TrEMBL
  ENSSSCT00060022744.1 UniProtKB/TrEMBL
  ENSSSCT00065039444.1 UniProtKB/TrEMBL
  ENSSSCT00065039447.1 UniProtKB/TrEMBL
  ENSSSCT00070023913.1 UniProtKB/TrEMBL
  ENSSSCT00070023918.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
KEGG Report ssc:100153840 UniProtKB/TrEMBL
NCBI Gene RCN2 ENTREZGENE
PANTHER RETICULOCALBIN UniProtKB/TrEMBL
  RETICULOCALBIN-2 UniProtKB/TrEMBL
Pfam EF-hand_5 UniProtKB/TrEMBL
  EF-hand_7 UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A4X1TRI5_PIG UniProtKB/TrEMBL
  A0A4X1TWE4 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QY21_PIG UniProtKB/TrEMBL
  A0A8D0KC31 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1NG46 ENTREZGENE, UniProtKB/TrEMBL
  F1SJ93 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:92181 ENTREZGENE