LOC106560171 (transmembrane O-methyltransferase) - Rat Genome Database

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Gene: LOC106560171 (transmembrane O-methyltransferase) Canis lupus familiaris
Analyze
Symbol: LOC106560171 (Ensembl: TOMT)
Name: transmembrane O-methyltransferase
RGD ID: 12140403
Description: ENCODES a protein that exhibits catechol O-methyltransferase activity (inferred); methyltransferase activity (inferred); O-methyltransferase activity (inferred); INVOLVED IN auditory receptor cell development (inferred); catecholamine catabolic process (inferred); catecholamine metabolic process (inferred); ASSOCIATED WITH 3-methylglutaconic aciduria type 7b (ortholog); autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 63 (ortholog); FOUND IN apical part of cell (inferred); cytoplasm (inferred); endoplasmic reticulum (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12125,975,547 - 25,981,097 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2125,743,343 - 25,751,089 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02126,182,525 - 26,190,272 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2126,184,399 - 26,189,875 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12125,973,788 - 25,981,524 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02126,189,907 - 26,197,654 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02126,091,538 - 26,099,285 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LOC106560171
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12125,975,547 - 25,981,097 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2125,743,343 - 25,751,089 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02126,182,525 - 26,190,272 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2126,184,399 - 26,189,875 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12125,973,788 - 25,981,524 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02126,189,907 - 26,197,654 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02126,091,538 - 26,099,285 (-)NCBIUU_Cfam_GSD_1.0
LRTOMT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381172,080,850 - 72,110,782 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1172,080,331 - 72,110,782 (+)EnsemblGRCh38hg38GRCh38
GRCh371171,791,896 - 71,821,828 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361171,469,553 - 71,485,589 (+)NCBINCBI36Build 36hg18NCBI36
Celera1169,093,343 - 69,123,775 (+)NCBICelera
Cytogenetic Map11q13.4NCBI
HuRef1168,084,985 - 68,115,422 (+)NCBIHuRef
CHM1_11171,675,200 - 71,705,636 (+)NCBICHM1_1
T2T-CHM13v2.01172,007,754 - 72,037,672 (+)NCBIT2T-CHM13v2.0
Tomt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397101,549,010 - 101,555,572 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7101,547,577 - 101,555,566 (-)EnsemblGRCm39 Ensembl
GRCm387101,899,803 - 101,906,407 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7101,898,370 - 101,906,359 (-)EnsemblGRCm38mm10GRCm38
MGSCv377109,048,317 - 109,054,873 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367109,048,317 - 109,054,873 (-)NCBIMGSCv36mm8
Celera7102,274,130 - 102,280,686 (-)NCBICelera
Cytogenetic Map7E2NCBI
cM Map754.68NCBI
Lrtomt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81165,678,654 - 165,680,703 (-)NCBIGRCr8
mRatBN7.21156,266,655 - 156,268,704 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1156,266,655 - 156,268,704 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1164,250,824 - 164,252,873 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01171,430,918 - 171,432,967 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01164,308,366 - 164,310,415 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01166,985,468 - 166,989,681 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,986,013 - 166,988,062 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,176,767 - 173,178,816 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41159,362,010 - 159,364,059 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1154,340,313 - 154,342,362 (-)NCBICelera
Cytogenetic Map1q32NCBI
LOC100967430
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2973,030,257 - 73,059,366 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11174,072,707 - 74,101,555 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01167,160,599 - 67,189,746 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11170,384,068 - 70,400,764 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1170,392,081 - 70,412,641 (+)Ensemblpanpan1.1panPan2

Variants

.
Variants in LOC106560171
34 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014122499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014122500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022407742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022407743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038430255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038430256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038430257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038430258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038505606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038568794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038568795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038568796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038568797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038632965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038632966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038632967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038632968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005298718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005313245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005375690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005409663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00845018562   ⟹   ENSCAFP00845014481
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2126,184,399 - 26,189,875 (-)Ensembl
RefSeq Acc Id: XM_014122499   ⟹   XP_013977974
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12125,975,547 - 25,981,097 (-)NCBI
Dog10K_Boxer_Tasha2125,743,343 - 25,751,069 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014122500   ⟹   XP_013977975
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12125,975,547 - 25,981,094 (-)NCBI
Dog10K_Boxer_Tasha2125,743,343 - 25,751,065 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022407742   ⟹   XP_022263450
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12125,975,547 - 25,981,094 (-)NCBI
Dog10K_Boxer_Tasha2125,743,343 - 25,751,065 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022407743   ⟹   XP_022263451
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12125,975,547 - 25,981,094 (-)NCBI
Dog10K_Boxer_Tasha2125,743,343 - 25,751,067 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038430255   ⟹   XP_038286183
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02126,182,525 - 26,190,252 (-)NCBI
RefSeq Acc Id: XM_038430256   ⟹   XP_038286184
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02126,182,525 - 26,190,247 (-)NCBI
RefSeq Acc Id: XM_038430257   ⟹   XP_038286185
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02126,182,525 - 26,190,250 (-)NCBI
RefSeq Acc Id: XM_038430258   ⟹   XP_038286186
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02126,182,525 - 26,190,247 (-)NCBI
RefSeq Acc Id: XM_038505606   ⟹   XP_038361534
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12125,973,788 - 25,981,524 (-)NCBI
RefSeq Acc Id: XM_038568794   ⟹   XP_038424722
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02126,091,538 - 26,099,265 (-)NCBI
RefSeq Acc Id: XM_038568795   ⟹   XP_038424723
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02126,091,538 - 26,099,261 (-)NCBI
RefSeq Acc Id: XM_038568796   ⟹   XP_038424724
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02126,091,538 - 26,099,263 (-)NCBI
RefSeq Acc Id: XM_038568797   ⟹   XP_038424725
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02126,091,538 - 26,099,261 (-)NCBI
RefSeq Acc Id: XM_038632965   ⟹   XP_038488893
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02126,189,907 - 26,197,634 (-)NCBI
RefSeq Acc Id: XM_038632966   ⟹   XP_038488894
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02126,189,907 - 26,197,630 (-)NCBI
RefSeq Acc Id: XM_038632967   ⟹   XP_038488895
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02126,189,907 - 26,197,632 (-)NCBI
RefSeq Acc Id: XM_038632968   ⟹   XP_038488896
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02126,189,907 - 26,197,630 (-)NCBI
RefSeq Acc Id: XR_005298718
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02126,187,607 - 26,190,272 (-)NCBI
RefSeq Acc Id: XR_005313245
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2125,748,425 - 25,751,089 (-)NCBI
RefSeq Acc Id: XR_005375690
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02126,096,620 - 26,099,285 (-)NCBI
RefSeq Acc Id: XR_005409663
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02126,194,989 - 26,197,654 (-)NCBI
RefSeq Acc Id: XP_013977974   ⟸   XM_014122499
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JTX8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013977975   ⟸   XM_014122500
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RGA8 (UniProtKB/TrEMBL),   A0A8I3NGA3 (UniProtKB/TrEMBL),   A0A8C0T818 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022263451   ⟸   XM_022407743
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RGA8 (UniProtKB/TrEMBL),   A0A8I3NGA3 (UniProtKB/TrEMBL),   A0A8C0T818 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022263450   ⟸   XM_022407742
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RGA8 (UniProtKB/TrEMBL),   A0A8I3NGA3 (UniProtKB/TrEMBL),   A0A8C0T818 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038361534   ⟸   XM_038505606
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038488893   ⟸   XM_038632965
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038488895   ⟸   XM_038632967
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038488896   ⟸   XM_038632968
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038488894   ⟸   XM_038632966
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038286183   ⟸   XM_038430255
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JTX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038286185   ⟸   XM_038430257
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RGA8 (UniProtKB/TrEMBL),   A0A8I3NGA3 (UniProtKB/TrEMBL),   A0A8C0T818 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038286186   ⟸   XM_038430258
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RGA8 (UniProtKB/TrEMBL),   A0A8I3NGA3 (UniProtKB/TrEMBL),   A0A8C0T818 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038286184   ⟸   XM_038430256
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RGA8 (UniProtKB/TrEMBL),   A0A8I3NGA3 (UniProtKB/TrEMBL),   A0A8C0T818 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038424722   ⟸   XM_038568794
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JTX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038424724   ⟸   XM_038568796
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RGA8 (UniProtKB/TrEMBL),   A0A8C0T818 (UniProtKB/TrEMBL),   A0A8I3NGA3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038424725   ⟸   XM_038568797
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RGA8 (UniProtKB/TrEMBL),   A0A8C0T818 (UniProtKB/TrEMBL),   A0A8I3NGA3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038424723   ⟸   XM_038568795
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RGA8 (UniProtKB/TrEMBL),   A0A8C0T818 (UniProtKB/TrEMBL),   A0A8I3NGA3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845014481   ⟸   ENSCAFT00845018562


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005785 UniProtKB/TrEMBL
  ENSCAFG00030009466 UniProtKB/TrEMBL
  ENSCAFG00040020532 UniProtKB/TrEMBL
  ENSCAFG00845010540 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000043873.4 UniProtKB/TrEMBL
  ENSCAFT00030017519.1 UniProtKB/TrEMBL
  ENSCAFT00040037964.1 UniProtKB/TrEMBL
  ENSCAFT00845018562 ENTREZGENE
  ENSCAFT00845018562.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro SAM-dependent_MTases UniProtKB/TrEMBL
  SAM_O-MeTrfase UniProtKB/TrEMBL
NCBI Gene LOC106560171 ENTREZGENE
PANTHER CATECHOL O-METHYLTRANSFERASE 1-RELATED UniProtKB/TrEMBL
  PTHR43836:SF1 UniProtKB/TrEMBL
Pfam Methyltransf_3 UniProtKB/TrEMBL
PROSITE SAM_OMT_I UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A8C0JTX8 ENTREZGENE
  A0A8C0RGA8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0T818 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NGA3 ENTREZGENE, UniProtKB/TrEMBL