LOC100967430 (leucine-rich repeat-containing protein 51) - Rat Genome Database

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Gene: LOC100967430 (leucine-rich repeat-containing protein 51) Pan paniscus
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Symbol: LOC100967430 (Ensembl: TOMT)
Name: leucine-rich repeat-containing protein 51 (Ensembl:transmembrane O-methyltransferase)
RGD ID: 12027930
Description: ENCODES a protein that exhibits catechol O-methyltransferase activity (inferred); methyltransferase activity (inferred); O-methyltransferase activity (inferred); INVOLVED IN auditory receptor cell development (inferred); catecholamine catabolic process (inferred); catecholamine metabolic process (inferred); ASSOCIATED WITH 3-methylglutaconic aciduria type 7b (ortholog); autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 63 (ortholog); FOUND IN apical part of cell (inferred); cytoplasm (inferred); endoplasmic reticulum (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine rich transmembrane and O-methyltransferase domain containing; LOC103782651; LRTOMT; transmembrane O-methyltransferase
RGD Orthologs
Human
Mouse
Rat
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2973,030,257 - 73,059,366 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11174,072,707 - 74,101,555 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01167,160,599 - 67,189,746 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11170,384,068 - 70,400,764 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1170,392,081 - 70,412,641 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC100967430
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2973,030,257 - 73,059,366 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11174,072,707 - 74,101,555 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01167,160,599 - 67,189,746 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11170,384,068 - 70,400,764 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1170,392,081 - 70,412,641 (+)Ensemblpanpan1.1panPan2
LRTOMT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381172,080,850 - 72,110,782 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1172,080,331 - 72,110,782 (+)EnsemblGRCh38hg38GRCh38
GRCh371171,791,896 - 71,821,828 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361171,469,553 - 71,485,589 (+)NCBINCBI36Build 36hg18NCBI36
Celera1169,093,343 - 69,123,775 (+)NCBICelera
Cytogenetic Map11q13.4NCBI
HuRef1168,084,985 - 68,115,422 (+)NCBIHuRef
CHM1_11171,675,200 - 71,705,636 (+)NCBICHM1_1
T2T-CHM13v2.01172,007,754 - 72,037,672 (+)NCBIT2T-CHM13v2.0
Tomt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397101,549,010 - 101,555,572 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7101,547,577 - 101,555,566 (-)EnsemblGRCm39 Ensembl
GRCm387101,899,803 - 101,906,407 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7101,898,370 - 101,906,359 (-)EnsemblGRCm38mm10GRCm38
MGSCv377109,048,317 - 109,054,873 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367109,048,317 - 109,054,873 (-)NCBIMGSCv36mm8
Celera7102,274,130 - 102,280,686 (-)NCBICelera
Cytogenetic Map7E2NCBI
cM Map754.68NCBI
Lrtomt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81165,678,654 - 165,680,703 (-)NCBIGRCr8
mRatBN7.21156,266,655 - 156,268,704 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1156,266,655 - 156,268,704 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1164,250,824 - 164,252,873 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01171,430,918 - 171,432,967 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01164,308,366 - 164,310,415 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01166,985,468 - 166,989,681 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,986,013 - 166,988,062 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,176,767 - 173,178,816 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41159,362,010 - 159,364,059 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1154,340,313 - 154,342,362 (-)NCBICelera
Cytogenetic Map1q32NCBI
LOC106560171
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12125,975,547 - 25,981,097 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2125,743,343 - 25,751,089 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02126,182,525 - 26,190,272 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2126,184,399 - 26,189,875 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12125,973,788 - 25,981,524 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02126,189,907 - 26,197,654 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02126,091,538 - 26,099,285 (-)NCBIUU_Cfam_GSD_1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000039863   ⟹   ENSPPAP00000017163
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1170,392,081 - 70,399,393 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000039875   ⟹   ENSPPAP00000017175
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1170,392,120 - 70,400,764 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000039878   ⟹   ENSPPAP00000017178
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1170,392,812 - 70,412,319 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000039880   ⟹   ENSPPAP00000017180
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1170,392,812 - 70,398,897 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000039886   ⟹   ENSPPAP00000017186
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1170,398,936 - 70,412,606 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000039889   ⟹   ENSPPAP00000017189
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1170,406,731 - 70,412,641 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000039892   ⟹   ENSPPAP00000017191
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1170,409,067 - 70,412,606 (+)Ensembl
RefSeq Acc Id: XM_008968670   ⟹   XP_008966918
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2973,030,361 - 73,046,639 (+)NCBI
NHGRI_mPanPan11174,072,707 - 74,087,696 (+)NCBI
Mhudiblu_PPA_v01167,160,905 - 67,177,183 (+)NCBI
PanPan1.11170,384,068 - 70,400,764 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055093746   ⟹   XP_054949721
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2973,034,241 - 73,046,639 (+)NCBI
NHGRI_mPanPan11174,076,591 - 74,087,696 (+)NCBI
RefSeq Acc Id: XM_063608655   ⟹   XP_063464725
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2973,030,257 - 73,046,639 (+)NCBI
RefSeq Acc Id: XM_063608656   ⟹   XP_063464726
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2973,030,363 - 73,046,639 (+)NCBI
RefSeq Acc Id: XM_063608657   ⟹   XP_063464727
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2973,030,257 - 73,059,366 (+)NCBI
RefSeq Acc Id: XP_008966918   ⟸   XM_008968670
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AJC8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000017191   ⟸   ENSPPAT00000039892
Ensembl Acc Id: ENSPPAP00000017189   ⟸   ENSPPAT00000039889
Ensembl Acc Id: ENSPPAP00000017186   ⟸   ENSPPAT00000039886
Ensembl Acc Id: ENSPPAP00000017175   ⟸   ENSPPAT00000039875
Ensembl Acc Id: ENSPPAP00000017178   ⟸   ENSPPAT00000039878
Ensembl Acc Id: ENSPPAP00000017163   ⟸   ENSPPAT00000039863
Ensembl Acc Id: ENSPPAP00000017180   ⟸   ENSPPAT00000039880
RefSeq Acc Id: XP_054949721   ⟸   XM_055093746
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AJC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063464727   ⟸   XM_063608657
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063464725   ⟸   XM_063608655
- Peptide Label: isoform X1
- UniProtKB: A0A2R9ANC0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063464726   ⟸   XM_063608656
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AJC8 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031661 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000039863.1 UniProtKB/TrEMBL
  ENSPPAT00000039875.1 UniProtKB/TrEMBL
  ENSPPAT00000039878.1 UniProtKB/TrEMBL
  ENSPPAT00000039880.1 UniProtKB/TrEMBL
  ENSPPAT00000039886.1 UniProtKB/TrEMBL
  ENSPPAT00000039889.1 UniProtKB/TrEMBL
  ENSPPAT00000039892.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Leu-rich_rpt UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
  SAM_O-MeTrfase UniProtKB/TrEMBL
KEGG Report pps:100967430 UniProtKB/TrEMBL
NCBI Gene LOC100967430 ENTREZGENE
PANTHER CATECHOL O-METHYLTRANSFERASE 1-RELATED UniProtKB/TrEMBL
  LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51 UniProtKB/TrEMBL
  PTHR43836:SF1 UniProtKB/TrEMBL
  PTHR46545 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
  LRR_9 UniProtKB/TrEMBL
  Methyltransf_3 UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
  SAM_OMT_I UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  Outer arm dynein light chain 1 UniProtKB/TrEMBL
  SSF53335 UniProtKB/TrEMBL
UniProt A0A2R9AIJ3_PANPA UniProtKB/TrEMBL
  A0A2R9AIJ7_PANPA UniProtKB/TrEMBL
  A0A2R9AJC8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AJE3_PANPA UniProtKB/TrEMBL
  A0A2R9ANC0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ANC6_PANPA UniProtKB/TrEMBL
  A0A2R9AQN5_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-06-11 LOC100967430  leucine-rich repeat-containing protein 51  LOC103782651  transmembrane O-methyltransferase  Data merged from RGD:11796683 737654 PROVISIONAL