RIPPLY1 (ripply transcriptional repressor 1) - Rat Genome Database

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Gene: RIPPLY1 (ripply transcriptional repressor 1) Canis lupus familiaris
Analyze
Symbol: RIPPLY1
Name: ripply transcriptional repressor 1
RGD ID: 12138157
Description: INVOLVED IN bone morphogenesis (ortholog); Notch signaling pathway (ortholog); regulation of gene expression (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal hemophilia A (ortholog); Charcot-Marie-Tooth disease type X (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein ripply1; ripply1 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X80,457,529 - 80,461,281 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX80,457,912 - 80,460,765 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX66,576,613 - 66,584,440 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X82,100,917 - 82,108,742 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX82,101,300 - 82,104,153 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X79,565,821 - 79,573,644 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X81,275,674 - 81,283,507 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X81,054,482 - 81,062,303 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:26514726   PMID:30032202  


Genomics

Comparative Map Data
RIPPLY1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X80,457,529 - 80,461,281 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX80,457,912 - 80,460,765 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX66,576,613 - 66,584,440 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X82,100,917 - 82,108,742 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX82,101,300 - 82,104,153 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X79,565,821 - 79,573,644 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X81,275,674 - 81,283,507 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X81,054,482 - 81,062,303 (-)NCBIUU_Cfam_GSD_1.0
RIPPLY1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X106,900,063 - 106,903,341 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX106,900,063 - 106,903,341 (-)EnsemblGRCh38hg38GRCh38
GRCh37X106,143,293 - 106,146,571 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X106,030,104 - 106,033,217 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX106,614,678 - 106,617,946 (-)NCBICelera
Cytogenetic MapXq22.3NCBI
HuRefX95,771,654 - 95,774,579 (-)NCBIHuRef
CHM1_1X106,054,099 - 106,057,367 (-)NCBICHM1_1
T2T-CHM13v2.0X105,336,573 - 105,339,851 (-)NCBIT2T-CHM13v2.0
Ripply1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X138,680,430 - 138,683,102 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX138,680,298 - 138,683,102 (-)EnsemblGRCm39 Ensembl
GRCm38X139,779,681 - 139,782,353 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX139,779,549 - 139,782,353 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X136,314,220 - 136,316,892 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X135,126,012 - 135,128,717 (-)NCBIMGSCv36mm8
CeleraX123,042,286 - 123,044,955 (-)NCBICelera
Cytogenetic MapXF1NCBI
cM MapX61.35NCBI
Ripply1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X108,225,333 - 108,231,537 (-)NCBIGRCr8
mRatBN7.2X103,436,731 - 103,440,904 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX103,436,729 - 103,443,349 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X111,099,420 - 111,114,835 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX111,099,930 - 111,102,464 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0353,488,763 - 53,495,704 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X127,516,006 - 127,518,663 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera344,484,028 - 44,490,937 (+)NCBICelera
Cytogenetic MapXq32NCBI
Ripply1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554909,167,183 - 9,169,773 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554909,167,071 - 9,172,101 (+)NCBIChiLan1.0ChiLan1.0
RIPPLY1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X106,378,121 - 106,386,826 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X106,384,913 - 106,390,427 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X95,998,718 - 96,003,843 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X106,377,932 - 106,381,193 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX106,377,932 - 106,381,193 (-)Ensemblpanpan1.1panPan2
Ripply1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X79,809,010 - 79,812,866 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364997,846,041 - 7,848,400 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364997,845,180 - 7,848,954 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIPPLY1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX87,315,358 - 87,319,113 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X87,315,355 - 87,319,580 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X101,723,142 - 101,726,976 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RIPPLY1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X94,730,858 - 94,735,220 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606519,816,939 - 19,824,286 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ripply1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248039,868,707 - 9,879,909 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RIPPLY1
25 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
5 5 5 21 21 16 6 6 6 5 29 18 12 12 10

Sequence


Ensembl Acc Id: ENSCAFT00000046144   ⟹   ENSCAFP00000036423
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX80,457,912 - 80,460,765 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845030287   ⟹   ENSCAFP00845023749
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX82,101,300 - 82,104,153 (-)Ensembl
RefSeq Acc Id: XM_038450565   ⟹   XP_038306493
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X82,100,917 - 82,108,742 (-)NCBI
RefSeq Acc Id: XM_038450566   ⟹   XP_038306494
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X82,100,917 - 82,104,759 (-)NCBI
RefSeq Acc Id: XM_038464758   ⟹   XP_038320686
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_TashaX66,576,613 - 66,584,440 (-)NCBI
RefSeq Acc Id: XM_038524017   ⟹   XP_038379945
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X79,565,821 - 79,573,644 (-)NCBI
RefSeq Acc Id: XM_038524018   ⟹   XP_038379946
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X79,565,821 - 79,569,663 (-)NCBI
RefSeq Acc Id: XM_038587996   ⟹   XP_038443924
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X81,054,482 - 81,062,303 (-)NCBI
RefSeq Acc Id: XM_038587997   ⟹   XP_038443925
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X81,054,482 - 81,058,324 (-)NCBI
RefSeq Acc Id: XM_038652513   ⟹   XP_038508441
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X81,275,674 - 81,283,507 (-)NCBI
RefSeq Acc Id: XM_038652514   ⟹   XP_038508442
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X81,275,674 - 81,279,515 (-)NCBI
RefSeq Acc Id: XM_847751   ⟹   XP_852844
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X80,457,529 - 80,461,281 (-)NCBI
Dog10K_Boxer_TashaX66,576,613 - 66,580,455 (-)NCBI
Sequence:
RefSeq Acc Id: XP_852844   ⟸   XM_847751
- Peptide Label: isoform X2
- UniProtKB: A0A8I3P1S0 (UniProtKB/TrEMBL),   A0A8P0SRF1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000036423   ⟸   ENSCAFT00000046144
RefSeq Acc Id: XP_038379945   ⟸   XM_038524017
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038379946   ⟸   XM_038524018
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038508441   ⟸   XM_038652513
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038508442   ⟸   XM_038652514
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038306493   ⟸   XM_038450565
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038306494   ⟸   XM_038450566
- Peptide Label: isoform X2
- UniProtKB: A0A8I3P1S0 (UniProtKB/TrEMBL),   A0A8P0SRF1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038320686   ⟸   XM_038464758
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038443924   ⟸   XM_038587996
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038443925   ⟸   XM_038587997
- Peptide Label: isoform X2
Ensembl Acc Id: ENSCAFP00845023749   ⟸   ENSCAFT00845030287


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000029100 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00845017120 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000046144.3 UniProtKB/TrEMBL
  ENSCAFT00845030287 ENTREZGENE
  ENSCAFT00845030287.1 UniProtKB/TrEMBL
InterPro Ripply_fam UniProtKB/TrEMBL
NCBI Gene RIPPLY1 ENTREZGENE
PANTHER PROTEIN RIPPLY1 UniProtKB/TrEMBL
  PTHR16770 UniProtKB/TrEMBL
Pfam Ripply UniProtKB/TrEMBL
UniProt A0A8I3P1S0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SRF1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:45599 ENTREZGENE