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Gene: DENND2D (DENN domain containing 2D) Canis lupus familiaris

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Symbol:

DENND2D

Name:

DENN domain containing 2D

RGD ID:

12121238

Description:

ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

DENN domain-containing protein 2D

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DENND2D (DENN domain containing 2D)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Dennd2d (DENN domain containing 2D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Dennd2d (DENN domain containing 2D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dennd2d (DENN domain containing 2D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DENND2D (DENN domain containing 2D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dennd2d (DENN domain containing 2D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DENND2D (DENN domain containing 2D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DENND2D (DENN domain containing 2D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dennd2d (DENN domain containing 2D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	40,821,016 - 40,836,211 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	40,821,754 - 40,835,863 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	43,596,024 - 43,614,302 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	41,149,953 - 41,168,235 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	41,149,311 - 41,168,229 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	40,871,245 - 40,889,500 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	40,841,183 - 40,859,457 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	41,276,466 - 41,294,747 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytosol (IEA)

nucleoplasm (IEA)

Molecular Function

guanyl-nucleotide exchange factor activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

DENND2D
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	40,821,016 - 40,836,211 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	40,821,754 - 40,835,863 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	43,596,024 - 43,614,302 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	41,149,953 - 41,168,235 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	41,149,311 - 41,168,229 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	40,871,245 - 40,889,500 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	40,841,183 - 40,859,457 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	41,276,466 - 41,294,747 (+)	NCBI		UU_Cfam_GSD_1.0

DENND2D
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	111,185,969 - 111,204,578 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	111,185,969 - 111,204,535 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	111,728,591 - 111,747,200 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	111,531,324 - 111,544,804 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	109,976,779 - 109,990,260 (-)	NCBI		Celera
Cytogenetic Map	1	p13.3-p13.2	NCBI
HuRef	1	109,600,147 - 109,618,726 (-)	NCBI		HuRef
CHM1_1	1	111,843,731 - 111,862,311 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	111,200,774 - 111,219,466 (-)	NCBI		T2T-CHM13v2.0

Dennd2d
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	106,389,745 - 106,410,346 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	106,389,721 - 106,410,346 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	106,482,431 - 106,503,030 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	106,482,405 - 106,503,030 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	106,285,349 - 106,303,972 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	106,614,106 - 106,629,098 (+)	NCBI		MGSCv36	mm8
Celera	3	108,814,378 - 108,832,982 (+)	NCBI		Celera
Cytogenetic Map	3	F2.3	NCBI
cM Map	3	46.49	NCBI

Dennd2d
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	196,661,465 - 196,680,505 (+)	NCBI		GRCr8
mRatBN7.2	2	193,973,231 - 193,992,275 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	193,973,231 - 193,992,270 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	201,565,765 - 201,584,773 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	199,472,026 - 199,491,039 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	194,288,984 - 194,307,997 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	209,097,894 - 209,116,978 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	209,097,927 - 209,116,965 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	228,507,586 - 228,526,626 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	201,780,928 - 201,799,966 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	201,743,755 - 201,762,719 (+)	NCBI
Celera	2	186,655,681 - 186,674,719 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

Dennd2d
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955435	14,746,553 - 14,764,009 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955435	14,744,226 - 14,764,034 (-)	NCBI	ChiLan1.0	ChiLan1.0

DENND2D
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	115,838,988 - 115,856,425 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	114,987,907 - 115,006,981 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	113,830,395 - 113,850,077 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	126,497,131 - 126,515,688 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	126,497,131 - 126,514,484 (+)	Ensembl	panpan1.1		panPan2

Dennd2d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	17,544,930 - 17,561,999 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936704	2,552,591 - 2,569,120 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936704	2,552,147 - 2,564,664 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DENND2D
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	109,121,966 - 109,142,718 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	109,121,876 - 109,142,253 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	119,300,763 - 119,316,362 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DENND2D
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	22,374,530 - 22,391,855 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	22,378,279 - 22,391,421 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	36,085,148 - 36,102,499 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dennd2d
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624772	6,965,643 - 6,982,558 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624772	6,963,788 - 6,982,603 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in DENND2D
67 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038479729	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038479730	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038479731	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038479732	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038540999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038541000	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038541001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038541002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038551621	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038551627	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038551631	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038605127	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038605128	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038605129	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038605130	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038669801	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038669802	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038669803	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038669804	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_547226	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000031424 ⟹ ENSCAFP00000029251

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	40,821,754 - 40,835,863 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000065790 ⟹ ENSCAFP00000045933

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	40,822,189 - 40,835,863 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000073073 ⟹ ENSCAFP00000057264

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	40,821,836 - 40,835,863 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000087699 ⟹ ENSCAFP00000053699

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	40,821,836 - 40,835,863 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845002765 ⟹ ENSCAFP00845002191

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	6	41,149,311 - 41,168,229 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845002782 ⟹ ENSCAFP00845002208

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	6	41,149,311 - 41,168,229 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845002801 ⟹ ENSCAFP00845002225

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	6	41,149,311 - 41,168,229 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845002816 ⟹ ENSCAFP00845002239

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	6	41,153,885 - 41,168,229 (+)	Ensembl

RefSeq Acc Id:

XM_038479729 ⟹ XP_038335657

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	6	40,873,866 - 40,889,500 (+)	NCBI

RefSeq Acc Id:

XM_038479730 ⟹ XP_038335658

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	6	40,871,245 - 40,889,500 (+)	NCBI

RefSeq Acc Id:

XM_038479731 ⟹ XP_038335659

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	6	40,873,872 - 40,889,500 (+)	NCBI

RefSeq Acc Id:

XM_038479732 ⟹ XP_038335660

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	6	40,871,327 - 40,889,500 (+)	NCBI

RefSeq Acc Id:

XM_038540999 ⟹ XP_038396927

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	6	41,279,111 - 41,294,747 (+)	NCBI

RefSeq Acc Id:

XM_038541000 ⟹ XP_038396928

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	6	41,276,466 - 41,294,747 (+)	NCBI

RefSeq Acc Id:

XM_038541001 ⟹ XP_038396929

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	6	41,279,117 - 41,294,747 (+)	NCBI

RefSeq Acc Id:

XM_038541002 ⟹ XP_038396930

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	6	41,276,548 - 41,294,747 (+)	NCBI

RefSeq Acc Id:

XM_038551621 ⟹ XP_038407549

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	6	43,598,666 - 43,614,302 (+)	NCBI

RefSeq Acc Id:

XM_038551627 ⟹ XP_038407555

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	6	43,596,024 - 43,614,302 (+)	NCBI

RefSeq Acc Id:

XM_038551631 ⟹ XP_038407559

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	6	43,596,106 - 43,614,302 (+)	NCBI

RefSeq Acc Id:

XM_038605127 ⟹ XP_038461055

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	6	40,843,823 - 40,859,457 (+)	NCBI

RefSeq Acc Id:

XM_038605128 ⟹ XP_038461056

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	6	40,841,183 - 40,859,457 (+)	NCBI

RefSeq Acc Id:

XM_038605129 ⟹ XP_038461057

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	6	40,843,829 - 40,859,457 (+)	NCBI

RefSeq Acc Id:

XM_038605130 ⟹ XP_038461058

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	6	40,841,265 - 40,859,457 (+)	NCBI

RefSeq Acc Id:

XM_038669801 ⟹ XP_038525729

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	6	41,152,599 - 41,168,235 (+)	NCBI

RefSeq Acc Id:

XM_038669802 ⟹ XP_038525730

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	6	41,149,953 - 41,168,235 (+)	NCBI

RefSeq Acc Id:

XM_038669803 ⟹ XP_038525731

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	6	41,152,605 - 41,168,235 (+)	NCBI

RefSeq Acc Id:

XM_038669804 ⟹ XP_038525732

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	6	41,150,035 - 41,168,235 (+)	NCBI

RefSeq Acc Id:

XM_547226 ⟹ XP_547226

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	6	40,821,016 - 40,836,211 (+)	NCBI
Dog10K_Boxer_Tasha	6	43,598,672 - 43,614,302 (+)	NCBI

Sequence:

show sequence

GAGTGACCCCCAAGGCTGCTGATGCATCCAGTCCCCTCCTGTAGGCCAGGGAGGACGACCTGAG
GCAGTGCTTCCTATTTGGGAAGAGGGATTCTTTGCTGGAGCCCTGGGAACGGGTCCCGTGAGAG
AAGTCAGTCTTAGGATATATTGCAGGGGGTGAGAGATGGACCACTGTACATCATCCTGAGGTGT
CAGGAATTCTCCAGCTCAGAGATGGATTTGCTCCTATTTTTACCTCCAGGAGAAGAGAGTTTTA
GGTTCAGATCAATTTCCAGGACTCTCTCGCTAGAAAAAAATTTCCATTTGGAGAATTAATGGGC
CAAGTCTATTTATCTCCCTCAGGGGAGGCAGTGCCATGTTGGCTGTGGGGGAATGTTTGGGCCT
GTGCCCTGCTTGCAGTCCTGAAGCTCTGGAAGCTCCAGAGTGCAGCGGTGGGCCTTGCAGGGTT
TTTTTGGTGGTAGTGAATCAAGTTGAGATATGAAAGGTCAGGAGTTGAAGTTATGGGATCTAAG
ATCCCTGTCCTGGGGCTGGTGAGGTTCCAGTGCCCACAGTCTGCTGTTGGGCCTTCTTCCCTGT
CCCGAGGTTGTGAATAAACTCACTGCACAGTGTGCAGCCCAGAATTCAAAGCCTTTAGCCCAGA
AGCAGCTGGGCCTTGGAGGTGTTTGCTCCTGACCTTTTCTCTTGCCACACCCTGGGGCTCTTGG
GAGGAGCTGAGGTCTGAGCTGCAGTGCCAGGATGCTGCCTTCTTGATGCGGTCGTTTTGTTGCC
TTCCTGGGTCCCGTCACATCCTTCTTGCTCAATCATTGGGTGCTCGGGATAGAAGCCGCCCTCC
CCTATCTGGAAGGCAGCACACGGCGTGGCTTCATGGAGCTGTGGTTGGAGACTGAAGCGGCAGC
CCTTCTCTCAGGCTCTCAGTAGCCAGTCTGTGTTGGAGGAAGGGGAAGCACTCCATGCCCCGAA
AGTTGGAGAAGATGGAAGGACAAGTGGTAGGCGGGATGCTCAGGCTCTTCCGCAACCGGCTGCC
TCGACTCCGAGCAGGATCTCTCCAGGAGAGGGAAGCTGTAAAGGAACCGGAAAGGGCCCAGGAG
ATCAGTCTGCCCACCTTTGCTGGAGGGCAACACTTCTTTGAATACCTCCTGGTGGTTTCCCTCA
AAAGAAAGAGTTCAGGGGATGACTATGAGCCCATCATCATCTACCAGTTTCCCAAGCGGGAGAA
CCTGCTTCGGGGCCAACAGGAGGAGGAGGAGCGGCTGCTCGGAGCCATTCCCTTGTTCTGCTTC
CCAGATGGGAATGCGTGGGCACCGCTCACTGAGTACCCCAGGGAGACCTTTTCCTTTGTTCTGA
CCAACGTGGATGGGAGCAGGAAGATTGGATACTGCAGGCGCCTCTTGCCCGCCGGCCGTGGCCC
TCGTCTTCCCAAGGTGTACTGCATCATCAGCTGCATCGGCTGCTTCGGCCTGTTCTCCAAGATC
CTGGATGAGGTGGAGAAGAGGCACCAGATCTCCATGGCGGTCATTTACCCATTCATGCAGGGCC
TCCGAGAGGCGGCCTTCCCTGCTCCCGGGAAGACCGTCACGCTCAAGAGCTTCATCCCAGACTC
GGGCACTGAGTTCATCTCCCTGACACGGCCCCTGGACTCCCACCTAGAACACGTGGATTTTAGT
GTTCTGCTGCGCTGTCTCAGTTTTGAGCAGATCCTTCAGATCTTTGCCTCTGCTGTGCTGGAGA
GAAGAATCATCTTTCTGGCAGAAGGTCTCAGCACCCTGTCTCAGTGCATCCATGCTGCTGCTGC
GCTGCTCTACCCTTTCAGCTGGGCACACACCTACATCCCCGTTGTCCCCGAGAGCCTTCTGGAC
ACTGTCTGCTGCCCCACTCCCTTCATGGTCGGAGTACAAATGCGCTTTCAGCAGCAGGTTATGG
ATAGCCCCATGGAAGAGGTCCTGCTGGTGAATCTTTGTGAAGGAACCTTCTTAATGTCAGTTGG
TGACGAAAAAGATATCCTTCCACCCAAGCTTCAGGATGACATCTTAGACTCCCTTGGTCAGGGG
ACCAATGAGTCACAGACTTCAGAACAGCTCAACGAGCATGTTTCGGGCCCATTTGTGCAGTTCT
TTGTCAAGACTGTGGGCCACTATGCTTCCTATATCAAGCGGGAGGCAAACGGGCAAGGCCACTT
CCAAGAACGAGCCTTCTATAAGGCTCTGACTTCCAAGACCAACCGCCGATTCGTGAAGAAGTTT
GTGAAGACACAGCTCTTCTCCCTTTTCATCCAGGAAGCGGAGAAGAGCAGGAACCCTCCTGCAG
GCTACTTCCAACGTAAGATACTTGAATATGAGGAACAGAAGAAACAGAAGAAATCAAGGGAAAA
GACTGTGAAATAAGAACTGTGGTCAACAGGAGGGACTGGACTCACAGGCCAGTTTTGGACTTTG
GCCCCTGCCAGCATGGTGGGACTGGCAAAGCTCACAGCCTCCAGAATCCACGGCCTCCTCTGAG
ACCTGGTAACCAGGTCTCGCTTCAGGCTGCTGTCTTGAGTTCGGGGTCCCTGGAATCCACTTTC
TCCAGACTCTGGAAGGCTCTGACATCTGTGCTCACAGAGCTGGGCTCCGAGCTGCATGTTCCGC
ACAGGTGACACAGAGTGGCAGAGTGGCACAGGTGCTATGGAGCCTCAGAAGTTGCTGGGACTGC
CCTCTTCCAGCATACAGAATCACAAAATCCTCAAAAGGGAAAGCAGTTGTGGCCCAAGGCTCAG
TCTCTTCACATAAAAAAGCAAGTCTGTGGACATGTGAAGATAAGAATAAAGATGAAAATCTTCT
TGTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_038335657	(Get FASTA)	NCBI Sequence Viewer
	XP_038335658	(Get FASTA)	NCBI Sequence Viewer
	XP_038335659	(Get FASTA)	NCBI Sequence Viewer
	XP_038335660	(Get FASTA)	NCBI Sequence Viewer
	XP_038396927	(Get FASTA)	NCBI Sequence Viewer
	XP_038396928	(Get FASTA)	NCBI Sequence Viewer
	XP_038396929	(Get FASTA)	NCBI Sequence Viewer
	XP_038396930	(Get FASTA)	NCBI Sequence Viewer
	XP_038407549	(Get FASTA)	NCBI Sequence Viewer
	XP_038407555	(Get FASTA)	NCBI Sequence Viewer
	XP_038407559	(Get FASTA)	NCBI Sequence Viewer
	XP_038461055	(Get FASTA)	NCBI Sequence Viewer
	XP_038461056	(Get FASTA)	NCBI Sequence Viewer
	XP_038461057	(Get FASTA)	NCBI Sequence Viewer
	XP_038461058	(Get FASTA)	NCBI Sequence Viewer
	XP_038525729	(Get FASTA)	NCBI Sequence Viewer
	XP_038525730	(Get FASTA)	NCBI Sequence Viewer
	XP_038525731	(Get FASTA)	NCBI Sequence Viewer
	XP_038525732	(Get FASTA)	NCBI Sequence Viewer
	XP_547226	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000029251.4
	ENSCAFP00000045933.2
	ENSCAFP00000057264.1
	ENSCAFP00030025627.1
	ENSCAFP00030025692.1
	ENSCAFP00030025781.1
	ENSCAFP00030025838.1
	ENSCAFP00040020311.1
	ENSCAFP00040020378.1
	ENSCAFP00040020447.1
	ENSCAFP00845002191
	ENSCAFP00845002191.1
	ENSCAFP00845002208.1
	ENSCAFP00845002225.1
	ENSCAFP00845002239
	ENSCAFP00845002239.1

RefSeq Acc Id:	XP_547226 ⟸ XM_547226
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0K940 (UniProtKB/TrEMBL), A0A8C0KB93 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPRKLEKMEGQVVGGMLRLFRNRLPRLRAGSLQEREAVKEPERAQEISLPTFAGGQHFFEYLLV VSLKRKSSGDDYEPIIIYQFPKRENLLRGQQEEEERLLGAIPLFCFPDGNAWAPLTEYPRETFS FVLTNVDGSRKIGYCRRLLPAGRGPRLPKVYCIISCIGCFGLFSKILDEVEKRHQISMAVIYPF MQGLREAAFPAPGKTVTLKSFIPDSGTEFISLTRPLDSHLEHVDFSVLLRCLSFEQILQIFASA VLERRIIFLAEGLSTLSQCIHAAAALLYPFSWAHTYIPVVPESLLDTVCCPTPFMVGVQMRFQQ QVMDSPMEEVLLVNLCEGTFLMSVGDEKDILPPKLQDDILDSLGQGTNESQTSEQLNEHVSGPF VQFFVKTVGHYASYIKREANGQGHFQERAFYKALTSKTNRRFVKKFVKTQLFSLFIQEAEKSRN PPAGYFQRKILEYEEQKKQKKSREKTVK hide sequence

Ensembl Acc Id:

ENSCAFP00000029251 ⟸ ENSCAFT00000031424

Ensembl Acc Id:

ENSCAFP00000057264 ⟸ ENSCAFT00000073073

Ensembl Acc Id:

ENSCAFP00000053699 ⟸ ENSCAFT00000087699

Ensembl Acc Id:

ENSCAFP00000045933 ⟸ ENSCAFT00000065790

RefSeq Acc Id:	XP_038335658 ⟸ XM_038479730
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038335660 ⟸ XM_038479732
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038335657 ⟸ XM_038479729
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038335659 ⟸ XM_038479731
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038461056 ⟸ XM_038605128
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038461058 ⟸ XM_038605130
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038461055 ⟸ XM_038605127
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038461057 ⟸ XM_038605129
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038525730 ⟸ XM_038669802
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0YWZ6 (UniProtKB/TrEMBL), A0A8I3MKV7 (UniProtKB/TrEMBL), A0A8C0KB93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038525732 ⟸ XM_038669804
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0KB93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038525729 ⟸ XM_038669801
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0SEY9 (UniProtKB/TrEMBL), A0A8I3MKY2 (UniProtKB/TrEMBL), A0A8C0KB93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038525731 ⟸ XM_038669803
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0K940 (UniProtKB/TrEMBL), A0A8C0KB93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038407555 ⟸ XM_038551627
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0YWZ6 (UniProtKB/TrEMBL), A0A8I3MKV7 (UniProtKB/TrEMBL), A0A8C0KB93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038407559 ⟸ XM_038551631
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0KB93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038407549 ⟸ XM_038551621
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0SEY9 (UniProtKB/TrEMBL), A0A8I3MKY2 (UniProtKB/TrEMBL), A0A8C0KB93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038396928 ⟸ XM_038541000
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0KB93 (UniProtKB/TrEMBL), A0A8C0YWZ6 (UniProtKB/TrEMBL), A0A8I3MKV7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038396930 ⟸ XM_038541002
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0KB93 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038396927 ⟸ XM_038540999
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0KB93 (UniProtKB/TrEMBL), A0A8C0SEY9 (UniProtKB/TrEMBL), A0A8I3MKY2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038396929 ⟸ XM_038541001
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0K940 (UniProtKB/TrEMBL), A0A8C0KB93 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845002208 ⟸ ENSCAFT00845002782

Ensembl Acc Id:

ENSCAFP00845002225 ⟸ ENSCAFT00845002801

Ensembl Acc Id:

ENSCAFP00845002239 ⟸ ENSCAFT00845002816

Ensembl Acc Id:

ENSCAFP00845002191 ⟸ ENSCAFT00845002765

Protein Domains

uDENN

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000019764	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030015968	UniProtKB/TrEMBL
	ENSCAFG00040012702	UniProtKB/TrEMBL
	ENSCAFG00845001602	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000031424.5	UniProtKB/TrEMBL
	ENSCAFT00000065790.2	UniProtKB/TrEMBL
	ENSCAFT00000073073.2	UniProtKB/TrEMBL
	ENSCAFT00030029404.1	UniProtKB/TrEMBL
	ENSCAFT00030029478.1	UniProtKB/TrEMBL
	ENSCAFT00030029587.1	UniProtKB/TrEMBL
	ENSCAFT00030029654.1	UniProtKB/TrEMBL
	ENSCAFT00040023411.1	UniProtKB/TrEMBL
	ENSCAFT00040023482.1	UniProtKB/TrEMBL
	ENSCAFT00040023558.1	UniProtKB/TrEMBL
	ENSCAFT00845002765	ENTREZGENE
	ENSCAFT00845002765.1	UniProtKB/TrEMBL
	ENSCAFT00845002782.1	UniProtKB/TrEMBL
	ENSCAFT00845002801.1	UniProtKB/TrEMBL
	ENSCAFT00845002816	ENTREZGENE
	ENSCAFT00845002816.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.450.200	UniProtKB/TrEMBL
	3.40.50.11500	UniProtKB/TrEMBL
InterPro	cDENN_dom	UniProtKB/TrEMBL
	dDENN_dom	UniProtKB/TrEMBL
	DENN_C	UniProtKB/TrEMBL
	DENN_domain_containing_2	UniProtKB/TrEMBL
	Tripartite_DENN	UniProtKB/TrEMBL
	uDENN_dom	UniProtKB/TrEMBL
NCBI Gene	DENND2D	ENTREZGENE
PANTHER	DENN DOMAIN-CONTAINING PROTEIN 2	UniProtKB/TrEMBL
	DENN DOMAIN-CONTAINING PROTEIN 2D	UniProtKB/TrEMBL
Pfam	dDENN	UniProtKB/TrEMBL
	DENN	UniProtKB/TrEMBL
	uDENN	UniProtKB/TrEMBL
PROSITE	DENN	UniProtKB/TrEMBL
SMART	dDENN	UniProtKB/TrEMBL
	DENN	UniProtKB/TrEMBL
	uDENN	UniProtKB/TrEMBL
UniProt	A0A8C0K940	ENTREZGENE
	A0A8C0KB93	ENTREZGENE
	A0A8C0NJY1_CANLF	UniProtKB/TrEMBL
	A0A8C0RLD0_CANLF	UniProtKB/TrEMBL
	A0A8C0SEY9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0SGB4_CANLF	UniProtKB/TrEMBL
	A0A8C0YWZ6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MGF8_CANLF	UniProtKB/TrEMBL
	A0A8I3MKV7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MKY2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3RRL5_CANLF	UniProtKB/TrEMBL
UniProt Secondary	A0A8P0T9B7	UniProtKB/TrEMBL
VGNC ID	VGNC:39888	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar