SP3 (Sp3 transcription factor) - Rat Genome Database

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Gene: SP3 (Sp3 transcription factor) Canis lupus familiaris
Analyze
Symbol: SP3
Name: Sp3 transcription factor
RGD ID: 12117192
Description: ENCODES a protein that exhibits chromatin binding (inferred); cis-regulatory region sequence-specific DNA binding (inferred); DNA binding (inferred); INVOLVED IN B cell differentiation (ortholog); definitive hemopoiesis (ortholog); embryonic camera-type eye morphogenesis (ortholog); ASSOCIATED WITH split hand-foot malformation 5 (ortholog); FOUND IN protein-DNA complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor Sp3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13618,023,750 - 18,086,995 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3618,024,627 - 18,077,587 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3618,030,699 - 18,085,623 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03618,154,210 - 18,209,148 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3618,152,355 - 18,209,033 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13618,234,479 - 18,289,351 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03618,232,972 - 18,287,863 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03618,336,948 - 18,391,940 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:19064501   PMID:30032202  


Genomics

Comparative Map Data
SP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13618,023,750 - 18,086,995 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3618,024,627 - 18,077,587 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3618,030,699 - 18,085,623 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03618,154,210 - 18,209,148 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3618,152,355 - 18,209,033 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13618,234,479 - 18,289,351 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03618,232,972 - 18,287,863 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03618,336,948 - 18,391,940 (-)NCBIUU_Cfam_GSD_1.0
SP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382173,900,775 - 173,965,702 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2173,880,850 - 173,965,373 (-)EnsemblGRCh38hg38GRCh38
GRCh372174,765,503 - 174,830,430 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362174,481,504 - 174,538,309 (-)NCBINCBI36Build 36hg18NCBI36
Celera2168,384,626 - 168,443,931 (-)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2166,650,849 - 166,709,905 (-)NCBIHuRef
CHM1_12174,778,156 - 174,837,417 (-)NCBICHM1_1
T2T-CHM13v2.02174,387,111 - 174,452,024 (-)NCBIT2T-CHM13v2.0
Sp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39272,766,774 - 72,810,790 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl272,766,771 - 72,810,790 (-)EnsemblGRCm39 Ensembl
GRCm38272,936,430 - 72,980,446 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl272,936,427 - 72,980,446 (-)EnsemblGRCm38mm10GRCm38
MGSCv37272,774,487 - 72,818,503 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36272,737,269 - 72,789,548 (-)NCBIMGSCv36mm8
Celera274,621,937 - 74,665,927 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map243.35NCBI
Sp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8378,219,421 - 78,272,318 (-)NCBIGRCr8
mRatBN7.2357,811,855 - 57,857,150 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl357,812,075 - 57,860,342 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0359,644,579 - 59,689,011 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl359,646,015 - 59,688,692 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0366,118,151 - 66,163,940 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0366,729,636 - 66,739,419 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4355,440,985 - 55,485,768 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera357,350,925 - 57,387,172 (-)NCBICelera
Cytogenetic Map3q23NCBI
Sp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554491,347,781 - 1,404,368 (+)NCBIChiLan1.0ChiLan1.0
SP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21376,573,271 - 76,630,819 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B76,588,245 - 76,645,598 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B61,185,975 - 61,243,155 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B178,639,630 - 178,698,313 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B178,639,677 - 178,692,848 (-)Ensemblpanpan1.1panPan2
Sp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303135,186,490 - 135,238,803 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365093,741,836 - 3,793,136 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365093,740,393 - 3,782,873 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1579,935,994 - 80,025,850 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11579,935,986 - 79,990,139 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21589,252,305 - 89,292,992 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11059,414,739 - 59,471,596 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1059,416,152 - 59,470,456 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040140,106,666 - 140,163,017 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478711,144,581 - 11,193,520 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SP3
560 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000020911   ⟹   ENSCAFP00000019415
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3618,024,627 - 18,077,587 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845052294   ⟹   ENSCAFP00845041017
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3618,152,355 - 18,209,033 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845052314   ⟹   ENSCAFP00845041034
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3618,154,218 - 18,208,289 (-)Ensembl
RefSeq Acc Id: XM_038447097   ⟹   XP_038303025
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03618,154,210 - 18,209,148 (-)NCBI
RefSeq Acc Id: XM_038463319   ⟹   XP_038319247
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3618,030,699 - 18,085,623 (-)NCBI
RefSeq Acc Id: XM_038521176   ⟹   XP_038377104
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13618,234,479 - 18,289,351 (-)NCBI
RefSeq Acc Id: XM_038584877   ⟹   XP_038440805
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03618,336,948 - 18,391,940 (-)NCBI
RefSeq Acc Id: XM_038649296   ⟹   XP_038505224
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03618,232,972 - 18,287,863 (-)NCBI
Ensembl Acc Id: ENSCAFP00000019415   ⟸   ENSCAFT00000020911
RefSeq Acc Id: XP_038377104   ⟸   XM_038521176
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038505224   ⟸   XM_038649296
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038303025   ⟸   XM_038447097
- Peptide Label: isoform X1
- UniProtKB: A0A8I3Q8J6 (UniProtKB/TrEMBL),   A0A8C0YYP3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038319247   ⟸   XM_038463319
- Peptide Label: isoform X1
- UniProtKB: A0A8P0PRS7 (UniProtKB/TrEMBL),   A0A8C0YYP3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038440805   ⟸   XM_038584877
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NIV3 (UniProtKB/TrEMBL),   A0A8C0YYP3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845041034   ⟸   ENSCAFT00845052314
Ensembl Acc Id: ENSCAFP00845041017   ⟸   ENSCAFT00845052294
Protein Domains
C2H2-type

Promoters
RGD ID:13689075
Promoter ID:EPDNEW_C7144
Type:initiation region
Name:SP3_1
Description:Sp3 transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13618,077,124 - 18,077,184EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000013169 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030017288 UniProtKB/TrEMBL
  ENSCAFG00040014844 UniProtKB/TrEMBL
  ENSCAFG00845029530 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000020911.5 UniProtKB/TrEMBL
  ENSCAFT00000102865.1 UniProtKB/TrEMBL
  ENSCAFT00030031918.1 UniProtKB/TrEMBL
  ENSCAFT00040027379.1 UniProtKB/TrEMBL
  ENSCAFT00845052294 ENTREZGENE
  ENSCAFT00845052294.1 UniProtKB/TrEMBL
  ENSCAFT00845052314.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene SP3 ENTREZGENE
PANTHER KRUEPPEL-LIKE TRANSCRIPTION FACTOR UniProtKB/TrEMBL
  PTHR23235:SF3 UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A8C0NIV3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0YYP3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q3H1_CANLF UniProtKB/TrEMBL
  A0A8I3Q8J6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PRS7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SHZ9_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:53107 ENTREZGENE