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Gene: PRPF18 (pre-mRNA processing factor 18) Canis lupus familiaris

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Symbol:

PRPF18

Name:

pre-mRNA processing factor 18

RGD ID:

12086625

Description:

INVOLVED IN negative regulation of protein metabolic process (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH CORPUS CALLOSUM, AGENESIS OF, WITH FACIAL ANOMALIES AND CEREBELLAR ATAXIA (ortholog); hypoparathyroidism-deafness-renal disease syndrome (ortholog); FOUND IN nuclear speck (inferred); nucleus (inferred); spliceosomal complex (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

pre-mRNA-splicing factor 18; PRP18 pre-mRNA processing factor 18 homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	22,868,184 - 22,922,647 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	19,927,607 - 19,981,026 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	23,174,819 - 23,228,055 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	23,174,827 - 23,228,046 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	20,374,375 - 20,427,960 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	21,209,121 - 21,262,690 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	21,837,171 - 21,891,059 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

CORPUS CALLOSUM, AGENESIS OF, WITH FACIAL ANOMALIES AND CEREBELLAR ATAXIA (ISO)

hypoparathyroidism-deafness-renal disease syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

generation of catalytic spliceosome for second transesterification step (IBA)

mRNA processing (IEA)

negative regulation of protein metabolic process (ISO)

RNA splicing (IEA)

Cellular Component

nuclear speck (IEA)

nucleus (IEA)

spliceosomal complex (IEA)

U2-type post-spliceosomal complex (IBA)

U4/U6 x U5 tri-snRNP complex (IBA)

U5 snRNP (IBA)

Molecular Function

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

spliceosome pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

PRPF18
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	22,868,184 - 22,922,647 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	19,927,607 - 19,981,026 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	23,174,819 - 23,228,055 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	23,174,827 - 23,228,046 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	20,374,375 - 20,427,960 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	21,209,121 - 21,262,690 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	21,837,171 - 21,891,059 (-)	NCBI		UU_Cfam_GSD_1.0

PRPF18
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	13,586,965 - 13,655,929 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	13,586,939 - 13,668,445 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	13,628,965 - 13,697,929 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	13,668,945 - 13,712,874 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	13,669,020 - 13,712,728	NCBI
Celera	10	13,556,054 - 13,599,997 (+)	NCBI		Celera
Cytogenetic Map	10	p13	NCBI
HuRef	10	13,540,560 - 13,584,503 (+)	NCBI		HuRef
CHM1_1	10	13,629,694 - 13,673,671 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	13,599,966 - 13,668,950 (+)	NCBI		T2T-CHM13v2.0

Prpf18
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	4,626,869 - 4,656,946 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	4,626,869 - 4,656,924 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	4,622,058 - 4,652,135 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	4,622,058 - 4,652,113 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	4,543,213 - 4,573,132 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	4,539,439 - 4,569,358 (-)	NCBI		MGSCv36	mm8
Celera	2	4,574,753 - 4,604,661 (-)	NCBI		Celera
Cytogenetic Map	2	A1	NCBI
cM Map	2	2.79	NCBI

Prpf18
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	78,539,004 - 78,570,483 (+)	NCBI		GRCr8
mRatBN7.2	17	73,630,560 - 73,661,210 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	73,630,571 - 73,690,979 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	77,123,582 - 77,154,138 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	80,959,480 - 80,990,038 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	75,007,036 - 75,037,592 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	77,601,914 - 77,632,507 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	77,601,877 - 77,663,980 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	79,256,708 - 79,287,301 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	84,741,279 - 84,773,449 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	17	73,067,705 - 73,098,132 (+)	NCBI		Celera
Cytogenetic Map	17	q12.3	NCBI

Prpf18
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955429	20,581,457 - 20,613,257 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955429	20,581,457 - 20,613,258 (-)	NCBI	ChiLan1.0	ChiLan1.0

PRPF18
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	26,106,223 - 26,175,189 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	26,111,563 - 26,155,440 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	13,584,517 - 13,628,389 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	13,915,987 - 13,959,812 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	13,915,943 - 13,959,830 (+)	Ensembl	panpan1.1		panPan2

Prpf18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	5,813,918 - 5,850,819 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936613	364,462 - 401,402 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936613	364,492 - 401,402 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PRPF18
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	48,061,728 - 48,164,499 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	48,062,229 - 48,122,222 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	52,848,767 - 52,884,941 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PRPF18
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	13,606,432 - 13,650,727 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	13,606,433 - 13,652,849 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666051	19,142,305 - 19,186,776 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Prpf18
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624805	1,602,782 - 1,637,099 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624805	1,593,697 - 1,635,987 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in PRPF18
560 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005617120	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038469348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038469349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038530090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038530091	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038594349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038594350	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038658416	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038658417	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_535182	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002617233	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00845028973 ⟹ ENSCAFP00845022792

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	23,174,827 - 23,228,046 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845028992 ⟹ ENSCAFP00845022807

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	23,174,828 - 23,228,030 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845029006 ⟹ ENSCAFP00845022817

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	23,174,833 - 23,228,046 (-)	Ensembl

RefSeq Acc Id:

XM_005617120 ⟹ XP_005617177

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	22,869,215 - 22,922,647 (-)	NCBI
Dog10K_Boxer_Tasha	2	19,927,607 - 19,981,026 (-)	NCBI

Sequence:

show sequence

GTCGGCTTCCGCCGGAAGCGGCTGCCGTCAGGCGTCGTCGGGGGTGCGAGCTTGGCGGGGGTGG
GTCGGCGGCTCCGGGGGCCCGAGGGCGAAGCTCGGGCGTAAGCCGGGCCGGCGACATGGACGTT
CTGAAGTCGGAGATCCTCCGGAAGCGGCAGCTGGTGGAGGACAGGAACCTGTTGGTGGAAAATA
AAAAGTATTTCAAGCGTAGTGAACTTGCGAAAAAAGAAGAGGAAGCCTATTTTGAAAGATGTGG
CTACAAGCCTATAAATGAGAAGCCATCTGGAGAGATACAGCCAAAAGAAGAGGACCAGAAACCA
TTAACTTCTTCGAATCCAGTGCTAGAACTTGAACTGGCAGAGGAAAAGTTACCCATGACTCTTT
CCAGGCAAGAGGTTATCAGAAGATTGAGAGAAAGAGGAGAACCCATCAGACTATTTGGAGAAAC
TGATTATGATGCTTTTCAACGTTTAAGAAAAATCGAGATCCTCACACCAGAAGTTAACAAGGGG
TTGAGGAATGATCTGAAAGCAGCTCTGGATAAGATTGACCAGCAGTACCTCAATGAGCTTGTGG
GGGGTCAGGAACCCGGAGAGGAAGACACACAGAATGATTTGAAAGTTCATGAAGAAAACACCAC
AATCGAAGAGTTAGAGGCATTGGGTGAGTCTTTAGGAAAAGGCGATGATCATAAAGACATGGAC
ATCATTACGAAGTTCCTTAAGTTCCTCCTGGGTGTTTGGGCTAAAGAGTTGAATGCCAGAGAAG
ATTATGTGAAGCGCAGTGTACAGGGCAAACTGAACAGTGCTACTCAAAAACAGACTGAATCCTA
TCTCAGACCTCTTTTCAGAAAGCTACGGAAAAGGAATCTTCCTGCTGATATTAAAGAATCCATA
ACAGATATTATTAAATTCATGTTGCAGAGAGAATATGTGAAGGCTAATGATGCTTATCTTCAGA
TGGCCATTGGAAATGCCCCTTGGCCCATAGGTGTCACCATGGTTGGTATCCATGCCAGAACTGG
TAGAGAAAAGATTTTTTCTAAGCATGTTGCACATGTTTTAAATGATGAAACACAGCGGAAATAT
ATTCAGGGATTGAAGAGGTTAATGACCATTTGCCAGAAGCACTTTCCTACAGATCCATCAAAAT
GTGTGGAGTACAATGCACTGTGATATCTGTGTGGTGTCTAAGTAACAAGAAACTGCAGTGGACG
TGGTACCGACTTCAGGAATCACCAGCAAGAGCGAGGGAAGAACAGTGCAGCCTCCTGTGGTTCC
GTTCTCCCCATGCTACTCTCTCGGTTATAAGAAATGGTGTTGGCTCTCCTGTCACCTCTGGCTG
CAAACTGATTTTTGTGTCATTTACTATAAATAGGCAAGAAATTAAATTCTGAAGACTTCTCCTC
GAATTTAAATGTGTAGACAACTGTCACAGAAGGGGGTCTAACGTGACCTCTTCCCTCTAGACCT
GAGAGTTGGCAGTTAGATGATTAAAAAGGAACATTTAAGGATGGACTTAATTTTTTCTGTAAAA
TATGATAATTTTCACATTGTCTTTTATGTAGCATTTATAAAAAGTATTTTTATATATTTCAACA
AAAATATGGAACCATTTAATGAAACTTTATAGTCCTTAAACGTTGCTGAACTTTTGCCATCTTG
CAATAGAATTGGAATGTAAATGTTATTACTGTTAACTCAAGTGTTGTTTTTCTTGCATTTCAAG
GCTTGCTTTTACCTTCTAAGGAGTGTAAATATTAGTATCTGTCACCTCTCGGGACAGAAAGAAT
TAACAGGAAATTGAAGTTCAAAAAAGATGGTATGTTATATCAATAGAAGTTTAAGTTAAGGAAC
CCCAATGCATCGAGGTTCAAGGTGAGATAGTGGATTGTCAAGCTAGCCAAGGACAGGGACGTTG
TGATGCCACTGGTTCTTCCCCGACCAGGACTGCCTGCGAGTCTCCCCGTTGGCCTGGCCTGTGC
TGACTGCTCCTCCAGACTCCACGCCGCTGGGCAGAGGAGCAAGGTGCCAGGACTCTGGTCACTG
CCCAAGACAGTAGGTCATGGGTCTGAGTTGGCACAGACAAGGACTTCTGAATTGCACACAGTGT
CCTACCCAGATACTGGTGATGAATTGCTGCGCTCTGCAAGCTGAGAGGACTCAGTTAATAGAGG
AAGGTGGGTGAATGGAGTGGACCTGCCCAGGTGAAGTGGGGTGTCGGACAGCAGTAAGGGGGGA
CTCCTGAGTCAGCACTGCCGAGCTGGAGATTCCCACTCTCCCCCCATGAGTGCATGACCCTGGG
TGTCACCTACCCCATCTCCGCCTCATTTGCCCCATCTCCAAGTGGTCTTGAGGAATCGGACTGT
ACCTCAGCGTGCTGTTGTGGTGTTCAAGTCAAATAAAATGCTTACCACACCGCCTGGCAGTTAA
GAGCTCAG

hide sequence

RefSeq Acc Id:

XM_038469348 ⟹ XP_038325276

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	20,374,375 - 20,427,960 (-)	NCBI

RefSeq Acc Id:

XM_038469349 ⟹ XP_038325277

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	20,374,375 - 20,427,959 (-)	NCBI

RefSeq Acc Id:

XM_038530090 ⟹ XP_038386018

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	21,837,171 - 21,891,059 (-)	NCBI

RefSeq Acc Id:

XM_038530091 ⟹ XP_038386019

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	21,837,171 - 21,891,058 (-)	NCBI

RefSeq Acc Id:

XM_038594349 ⟹ XP_038450277

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	21,209,121 - 21,262,690 (-)	NCBI

RefSeq Acc Id:

XM_038594350 ⟹ XP_038450278

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	21,209,121 - 21,262,689 (-)	NCBI

RefSeq Acc Id:

XM_038658416 ⟹ XP_038514344

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	23,174,819 - 23,228,055 (-)	NCBI

RefSeq Acc Id:

XM_038658417 ⟹ XP_038514345

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	23,174,819 - 23,228,054 (-)	NCBI

RefSeq Acc Id:

XM_535182 ⟹ XP_535182

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	22,869,215 - 22,922,646 (-)	NCBI
Dog10K_Boxer_Tasha	2	19,927,607 - 19,981,025 (-)	NCBI

Sequence:

show sequence

TCGGCTTCCGCCGGAAGCGGCTGCCGTCAGGCGTCGTCGGGGGTGCGAGCTTGGCGGGGGTGGG
TCGGCGGCTCCGGGGGCCCGAGGGCGAAGCTCGGGCGTAAGCCGGGCCGGCGACATGGACGTTC
TGAAGTCGGAGATCCTCCGGAAGCGGCAGCTGGTGGAGGACAGGAACCTGTTGGTGGAAAATAA
AAAGTATTTCAAGCGTAGTGAACTTGCGAAAAAAGAAGAGGAAGCCTATTTTGAAAGATGTGGC
TACAAGATACAGCCAAAAGAAGAGGACCAGAAACCATTAACTTCTTCGAATCCAGTGCTAGAAC
TTGAACTGGCAGAGGAAAAGTTACCCATGACTCTTTCCAGGCAAGAGGTTATCAGAAGATTGAG
AGAAAGAGGAGAACCCATCAGACTATTTGGAGAAACTGATTATGATGCTTTTCAACGTTTAAGA
AAAATCGAGATCCTCACACCAGAAGTTAACAAGGGGTTGAGGAATGATCTGAAAGCAGCTCTGG
ATAAGATTGACCAGCAGTACCTCAATGAGCTTGTGGGGGGTCAGGAACCCGGAGAGGAAGACAC
ACAGAATGATTTGAAAGTTCATGAAGAAAACACCACAATCGAAGAGTTAGAGGCATTGGGTGAG
TCTTTAGGAAAAGGCGATGATCATAAAGACATGGACATCATTACGAAGTTCCTTAAGTTCCTCC
TGGGTGTTTGGGCTAAAGAGTTGAATGCCAGAGAAGATTATGTGAAGCGCAGTGTACAGGGCAA
ACTGAACAGTGCTACTCAAAAACAGACTGAATCCTATCTCAGACCTCTTTTCAGAAAGCTACGG
AAAAGGAATCTTCCTGCTGATATTAAAGAATCCATAACAGATATTATTAAATTCATGTTGCAGA
GAGAATATGTGAAGGCTAATGATGCTTATCTTCAGATGGCCATTGGAAATGCCCCTTGGCCCAT
AGGTGTCACCATGGTTGGTATCCATGCCAGAACTGGTAGAGAAAAGATTTTTTCTAAGCATGTT
GCACATGTTTTAAATGATGAAACACAGCGGAAATATATTCAGGGATTGAAGAGGTTAATGACCA
TTTGCCAGAAGCACTTTCCTACAGATCCATCAAAATGTGTGGAGTACAATGCACTGTGATATCT
GTGTGGTGTCTAAGTAACAAGAAACTGCAGTGGACGTGGTACCGACTTCAGGAATCACCAGCAA
GAGCGAGGGAAGAACAGTGCAGCCTCCTGTGGTTCCGTTCTCCCCATGCTACTCTCTCGGTTAT
AAGAAATGGTGTTGGCTCTCCTGTCACCTCTGGCTGCAAACTGATTTTTGTGTCATTTACTATA
AATAGGCAAGAAATTAAATTCTGAAGACTTCTCCTCGAATTTAAATGTGTAGACAACTGTCACA
GAAGGGGGTCTAACGTGACCTCTTCCCTCTAGACCTGAGAGTTGGCAGTTAGATGATTAAAAAG
GAACATTTAAGGATGGACTTAATTTTTTCTGTAAAATATGATAATTTTCACATTGTCTTTTATG
TAGCATTTATAAAAAGTATTTTTATATATTTCAACAAAAATATGGAACCATTTAATGAAACTTT
ATAGTCCTTAAACGTTGCTGAACTTTTGCCATCTTGCAATAGAATTGGAATGTAAATGTTATTA
CTGTTAACTCAAGTGTTGTTTTTCTTGCATTTCAAGGCTTGCTTTTACCTTCTAAGGAGTGTAA
ATATTAGTATCTGTCACCTCTCGGGACAGAAAGAATTAACAGGAAATTGAAGTTCAAAAAAGAT
GGTATGTTATATCAATAGAAGTTTAAGTTAAGGAACCCCAATGCATCGAGGTTCAAGGTGAGAT
AGTGGATTGTCAAGCTAGCCAAGGACAGGGACGTTGTGATGCCACTGGTTCTTCCCCGACCAGG
ACTGCCTGCGAGTCTCCCCGTTGGCCTGGCCTGTGCTGACTGCTCCTCCAGACTCCACGCCGCT
GGGCAGAGGAGCAAGGTGCCAGGACTCTGGTCACTGCCCAAGACAGTAGGTCATGGGTCTGAGT
TGGCACAGACAAGGACTTCTGAATTGCACACAGTGTCCTACCCAGATACTGGTGATGAATTGCT
GCGCTCTGCAAGCTGAGAGGACTCAGTTAATAGAGGAAGGTGGGTGAATGGAGTGGACCTGCCC
AGGTGAAGTGGGGTGTCGGACAGCAGTAAGGGGGGACTCCTGAGTCAGCACTGCCGAGCTGGAG
ATTCCCACTCTCCCCCCATGAGTGCATGACCCTGGGTGTCACCTACCCCATCTCCGCCTCATTT
GCCCCATCTCCAAGTGGTCTTGAGGAATCGGACTGTACCTCAGCGTGCTGTTGTGGTGTTCAAG
TCAAATAAAATGCTTACCACACCGCCTGGCAGTTAAGAGCTCAG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005617177	(Get FASTA)	NCBI Sequence Viewer
	XP_038325276	(Get FASTA)	NCBI Sequence Viewer
	XP_038325277	(Get FASTA)	NCBI Sequence Viewer
	XP_038386018	(Get FASTA)	NCBI Sequence Viewer
	XP_038386019	(Get FASTA)	NCBI Sequence Viewer
	XP_038450277	(Get FASTA)	NCBI Sequence Viewer
	XP_038450278	(Get FASTA)	NCBI Sequence Viewer
	XP_038514344	(Get FASTA)	NCBI Sequence Viewer
	XP_038514345	(Get FASTA)	NCBI Sequence Viewer
	XP_535182	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000007051.3
	ENSCAFP00000033478.2
	ENSCAFP00000051964.2
	ENSCAFP00030025173.1
	ENSCAFP00030025243.1
	ENSCAFP00030025319.1
	ENSCAFP00040006130.1
	ENSCAFP00040006146.1
	ENSCAFP00040006160.1
	ENSCAFP00040006170.1
	ENSCAFP00845022792
	ENSCAFP00845022792.1
	ENSCAFP00845022807.1
	ENSCAFP00845022817
	ENSCAFP00845022817.1

RefSeq Acc Id:	XP_005617177 ⟸ XM_005617120
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0RL20 (UniProtKB/TrEMBL), A0A8I3NP29 (UniProtKB/TrEMBL), A0A8C0QB68 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDVLKSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKPINEKPSGEIQPKEED QKPLTSSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEV NKGLRNDLKAALDKIDQQYLNELVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHK DMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKRNLPADIK ESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQ RKYIQGLKRLMTICQKHFPTDPSKCVEYNAL hide sequence

RefSeq Acc Id:	XP_535182 ⟸ XM_535182
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0RL30 (UniProtKB/TrEMBL), A0A8C0K5W6 (UniProtKB/TrEMBL), A0A8I3NZU9 (UniProtKB/TrEMBL), A0A8C0QB68 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDVLKSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNP VLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNKGLRNDLK AALDKIDQQYLNELVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHKDMDIITKFL KFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKRNLPADIKESITDIIKF MLQREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKR LMTICQKHFPTDPSKCVEYNAL hide sequence

RefSeq Acc Id:	XP_038325276 ⟸ XM_038469348
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038325277 ⟸ XM_038469349
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038450277 ⟸ XM_038594349
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038450278 ⟸ XM_038594350
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038514344 ⟸ XM_038658416
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0RL20 (UniProtKB/TrEMBL), A0A8I3NP29 (UniProtKB/TrEMBL), A0A8C0QB68 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038514345 ⟸ XM_038658417
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0RL30 (UniProtKB/TrEMBL), A0A8C0K5W6 (UniProtKB/TrEMBL), A0A8I3NZU9 (UniProtKB/TrEMBL), A0A8C0QB68 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038386018 ⟸ XM_038530090
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0QB68 (UniProtKB/TrEMBL), A0A8C0RL20 (UniProtKB/TrEMBL), A0A8I3NP29 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038386019 ⟸ XM_038530091
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0K5W6 (UniProtKB/TrEMBL), A0A8C0QB68 (UniProtKB/TrEMBL), A0A8C0RL30 (UniProtKB/TrEMBL), A0A8I3NZU9 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845022807 ⟸ ENSCAFT00845028992

Ensembl Acc Id:

ENSCAFP00845022817 ⟸ ENSCAFT00845029006

Ensembl Acc Id:

ENSCAFP00845022792 ⟸ ENSCAFT00845028973

Protein Domains

Pre-mRNA processing factor 4 (PRP4)-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000004735	UniProtKB/TrEMBL
	ENSCAFG00030015685	UniProtKB/TrEMBL
	ENSCAFG00040003698	UniProtKB/TrEMBL
	ENSCAFG00845016307	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000007616.4	UniProtKB/TrEMBL
	ENSCAFT00000037850.5	UniProtKB/TrEMBL
	ENSCAFT00000091751.2	UniProtKB/TrEMBL
	ENSCAFT00030028876.1	UniProtKB/TrEMBL
	ENSCAFT00030028955.1	UniProtKB/TrEMBL
	ENSCAFT00030029044.1	UniProtKB/TrEMBL
	ENSCAFT00040007053.1	UniProtKB/TrEMBL
	ENSCAFT00040007069.1	UniProtKB/TrEMBL
	ENSCAFT00040007085.1	UniProtKB/TrEMBL
	ENSCAFT00040007097.1	UniProtKB/TrEMBL
	ENSCAFT00845028973	ENTREZGENE
	ENSCAFT00845028973.1	UniProtKB/TrEMBL
	ENSCAFT00845028992.1	UniProtKB/TrEMBL
	ENSCAFT00845029006	ENTREZGENE
	ENSCAFT00845029006.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.280.110	UniProtKB/TrEMBL
	Functional domain of the splicing factor Prp18	UniProtKB/TrEMBL
InterPro	Prp18	UniProtKB/TrEMBL
	PRP4-like	UniProtKB/TrEMBL
	PRP4-like_sf	UniProtKB/TrEMBL
	PRPF18	UniProtKB/TrEMBL
KEGG Report	cfa:477998	UniProtKB/TrEMBL
NCBI Gene	PRPF18	ENTREZGENE
PANTHER	PRE-MRNA-SPLICING FACTOR 18	UniProtKB/TrEMBL
	PTHR13007	UniProtKB/TrEMBL
Pfam	Prp18	UniProtKB/TrEMBL
	PRP4	UniProtKB/TrEMBL
SMART	SFM	UniProtKB/TrEMBL
Superfamily-SCOP	Functional domain of the splicing factor Prp18	UniProtKB/TrEMBL
	SSF158230	UniProtKB/TrEMBL
UniProt	A0A8C0K5W6	ENTREZGENE
	A0A8C0Q766_CANLF	UniProtKB/TrEMBL
	A0A8C0QB68	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0RL20	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0RL30	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NP29	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NUQ3_CANLF	UniProtKB/TrEMBL
	A0A8I3NZU9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0T4H3_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:111661	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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