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Gene: Prpf18 (pre-mRNA processing factor 18) Rattus norvegicus
Symbol: Prpf18
Name: pre-mRNA processing factor 18
RGD ID: 708550
Description: Involved in negative regulation of cellular protein metabolic process. Localizes to membrane. Orthologous to human PRPF18 (pre-mRNA processing factor 18); PARTICIPATES IN spliceosome pathway; INTERACTS WITH ammonium chloride; bisphenol A; Tributyltin oxide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KCRF; LOC171552; potassium channel regulatory factor; Pprf18; pre-mRNA-splicing factor 18; PRP18 homolog; PRP18 pre-mRNA processing factor 18 homolog; PRP18 pre-mRNA processing factor 18 homolog (S. cerevisiae); PRP18 pre-mRNA processing factor 18 homolog (yeast)
Homo sapiens (human) : PRPF18 (pre-mRNA processing factor 18)  HGNC  Alliance
Mus musculus (house mouse) : Prpf18 (pre-mRNA processing factor 18)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prpf18 (pre-mRNA processing factor 18)
Pan paniscus (bonobo/pygmy chimpanzee) : PRPF18 (pre-mRNA processing factor 18)
Canis lupus familiaris (dog) : PRPF18 (pre-mRNA processing factor 18)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prpf18 (pre-mRNA processing factor 18)
Sus scrofa (pig) : PRPF18 (pre-mRNA processing factor 18)
Chlorocebus sabaeus (African green monkey) : PRPF18 (pre-mRNA processing factor 18)
Heterocephalus glaber (naked mole-rat) : Prpf18 (pre-mRNA processing factor 18)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01777,601,914 - 77,632,507 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1777,601,877 - 77,663,980 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01779,256,708 - 79,287,301 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41784,741,279 - 84,773,449 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1773,067,705 - 73,098,132 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Prpf18
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 708550
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.