S100G (S100 calcium binding protein G)

Gene: S100G (S100 calcium binding protein G) Canis lupus familiaris

Analyze

Symbol:

S100G

Name:

S100 calcium binding protein G

RGD ID:

12084400

Description:

ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent protein binding (inferred); metal ion binding (inferred); INVOLVED IN response to organic cyclic compound (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); gestational diabetes (ortholog); FOUND IN apical plasma membrane (inferred); basolateral plasma membrane (inferred); collagen-containing extracellular matrix (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

protein S100-G

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	12,808,234 - 12,813,696 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	12,808,718 - 12,812,972 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	12,659,893 - 12,664,199 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	12,771,897 - 12,776,208 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	12,771,404 - 12,776,325 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	12,839,790 - 12,844,092 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	12,826,177 - 12,830,481 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	12,853,701 - 12,858,003 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

genetic disease (ISO)

gestational diabetes (ISO)

Neurodevelopmental Disorders (ISO)

pre-eclampsia (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

response to organic cyclic compound (ISO)

Cellular Component

apical plasma membrane (IEA)

basolateral plasma membrane (IEA)

collagen-containing extracellular matrix (IEA)

cytoplasm (IEA)

extracellular space (IEA)

Molecular Function

calcium ion binding (IEA)

calcium-dependent protein binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

transition metal ion binding (IEA)

vitamin D binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

calcium/calcium-mediated signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

S100G
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	12,808,234 - 12,813,696 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	12,808,718 - 12,812,972 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	12,659,893 - 12,664,199 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	12,771,897 - 12,776,208 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	12,771,404 - 12,776,325 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	12,839,790 - 12,844,092 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	12,826,177 - 12,830,481 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	12,853,701 - 12,858,003 (+)	NCBI		UU_Cfam_GSD_1.0

S100G
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	16,650,158 - 16,654,670 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	16,650,158 - 16,654,670 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	16,668,281 - 16,672,793 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	16,578,202 - 16,582,712 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	16,427,937 - 16,432,448	NCBI
Celera	X	20,786,679 - 20,791,190 (+)	NCBI		Celera
Cytogenetic Map	X	p22.2	NCBI
HuRef	X	14,422,857 - 14,427,585 (+)	NCBI		HuRef
CHM1_1	X	16,698,663 - 16,703,172 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	16,232,624 - 16,237,136 (+)	NCBI		T2T-CHM13v2.0

S100g
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	161,744,988 - 161,747,595 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	161,744,988 - 161,747,595 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	162,961,992 - 162,964,599 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	162,961,992 - 162,964,599 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	159,399,924 - 159,402,531 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	158,306,097 - 158,308,704 (-)	NCBI		MGSCv36	mm8
Celera	X	146,186,381 - 146,188,986 (-)	NCBI		Celera
Cytogenetic Map	X	F4	NCBI
cM Map	X	75.15	NCBI

S100g
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	35,337,636 - 35,340,205 (+)	NCBI		GRCr8
mRatBN7.2	X	31,705,853 - 31,708,422 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	31,705,866 - 31,708,433 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	32,740,258 - 32,742,781 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	36,175,676 - 36,178,203 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	32,364,662 - 32,367,187 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	33,442,820 - 33,445,714 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	33,443,186 - 33,445,709 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	33,790,619 - 33,793,188 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	52,446,817 - 52,449,342 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	52,500,285 - 52,502,811 (+)	NCBI
Celera	X	32,019,786 - 32,022,301 (+)	NCBI		Celera
Cytogenetic Map	X	q14	NCBI

S100g
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955519	1,622,522 - 1,625,164 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955519	1,623,695 - 1,625,164 (-)	NCBI	ChiLan1.0	ChiLan1.0

S100G
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	18,447,395 - 18,451,064 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	18,449,593 - 18,454,419 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	9,272,311 - 9,276,147 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	16,642,211 - 16,645,760 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	16,642,211 - 16,645,760 (+)	Ensembl	panpan1.1		panPan2

S100g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	5,930,101 - 5,934,996 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	5,930,140 - 5,935,000 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	5,931,158 - 5,934,986 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

S100G
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	13,107,402 - 13,114,213 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	13,107,611 - 13,114,213 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	14,053,102 - 14,059,701 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	X	p	NCBI

S100G
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	15,082,230 - 15,087,327 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	15,083,524 - 15,087,004 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666056	16,933,822 - 16,937,577 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

S100g
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624829	1,402,443 - 1,403,795 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624829	1,402,296 - 1,403,794 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in S100G
56 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium
Low		3						3
Below cutoff	5	5	1	1	1	1	1	5	3	5	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038449476	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038522909	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038586897	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038651409	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_843973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000110	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000175	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000046135 ⟹ ENSCAFP00000036287

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	X	12,808,718 - 12,812,972 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845054733 ⟹ ENSCAFP00845043052

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	X	12,771,404 - 12,776,325 (+)	Ensembl

RefSeq Acc Id:

XM_038449476 ⟹ XP_038305404

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	X	12,771,897 - 12,776,208 (+)	NCBI

RefSeq Acc Id:

XM_038522909 ⟹ XP_038378837

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	X	12,839,790 - 12,844,092 (+)	NCBI

RefSeq Acc Id:

XM_038586897 ⟹ XP_038442825

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	X	12,853,701 - 12,858,003 (+)	NCBI

RefSeq Acc Id:

XM_038651409 ⟹ XP_038507337

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	X	12,826,177 - 12,830,481 (+)	NCBI

RefSeq Acc Id:

XM_843973 ⟹ XP_849066

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	X	12,808,234 - 12,813,696 (+)	NCBI
Dog10K_Boxer_Tasha	X	12,659,893 - 12,664,199 (+)	NCBI

Sequence:

show sequence

AAGACTATAAAAGTCACGATCCTGCTCAACTCTTCACACTCCTACTTGATTCTTCTAGCTGCCT
TGCTGCCAGGCAACCAGGACACCAAAATGAGTGTAAAAAAGTCTCCCGAAGAACTGAAGAGCAT
TTTTGAAAAATACGCAGCCAAAGAAGGTGACCCAGACCAGCTGTCAAAGGCGGAGCTGAAGCTA
CTGATTGAGGCAGAATTTCCTACTTTACTGAAAGGTCCCAGCACCCTAGATGACCTCTTTCAAG
AACTGGACAAGAATGGAGATGGAGAAGTTAGTTTCGAAGAATTCCAGGTGTTAGTGAAGAAGAT
ATCCCAATGAAGGGAAAAAACCAAAACAATATATCATTCCTAGCACCAAAAGAAGAGCACCTGG
GATGTGGCCCCATTCTATACACAATAGCTAATGTCTGTTTAATTCTTGCAATTATAATGATCTG
GTGGTGAGGTCCAAACACTGTTAATAAAGAAATTCTTAGACATGTCTCTCCTTGTCAAATACTG
ACCCCCATTGCTTAATAGATTTGAAAGTAACCTTAGTCTAATGCATCTAATTTTATATCTTTTT
TTTTTTTTTTTTTAAGAAAGGCTGAGAATAGTTCATGATCTTCACTAAGACTGCAAAGATAGTG
TCAGGCTTAGAAAGAATTCTGACATGCCAAACTAACGCCCTTACTCCAGCCTTCCACCAGAATA
GCCCTGTTCCCACTCTCCCTCCCCAGCCACTCAGTGCTCACATCATTTCCGATTCCAACTCTAG
TGAACAGCTAGTAAGGAGCAGTCTTCAAAAAACCAACACTTGTCTTTAAAGTCACCTCCAGGAC
TCACCATGTTTTTTGAATCATTGACCTTCTCATAGAGTAGAAGCATTACAGGACCAAGAGTCAC
TTCTGTTCCATCACTGAGGGGTGGCCTTGGTTGTGGCATGTGATGTGTAAAACAAAAGGGACAG
GAAGACATAGGGCCCTCCCGGCTCCCACAGCCTGTGGTGCTGGGACTGTTAGGAGCTGAGAAAC
AGTGAACCCTCAAATTCCACTTGCTGAGTC

hide sequence

Protein Sequences


Protein RefSeqs	XP_038305404	(Get FASTA)	NCBI Sequence Viewer
	XP_038378837	(Get FASTA)	NCBI Sequence Viewer
	XP_038442825	(Get FASTA)	NCBI Sequence Viewer
	XP_038507337	(Get FASTA)	NCBI Sequence Viewer
	XP_849066	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000036287.3
	ENSCAFP00040022927.1
	ENSCAFP00845043052.1

RefSeq Acc Id:	XP_849066 ⟸ XM_843973
- UniProtKB:	A0A8C0SKA9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSVKKSPEELKSIFEKYAAKEGDPDQLSKAELKLLIEAEFPTLLKGPSTLDDLFQELDKNGDGE VSFEEFQVLVKKISQ hide sequence

RefSeq Acc Id:

ENSCAFP00000036287 ⟸ ENSCAFT00000046135

RefSeq Acc Id:

XP_038378837 ⟸ XM_038522909

RefSeq Acc Id:

XP_038507337 ⟸ XM_038651409

RefSeq Acc Id:	XP_038305404 ⟸ XM_038449476
- UniProtKB:	A0A8C0SKA9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038442825 ⟸ XM_038586897
- UniProtKB:	A0A8C0SKA9 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845043052 ⟸ ENSCAFT00845054733

Protein Domains

EF-hand

Promoters

RGD ID:

13689268

Promoter ID:

EPDNEW_C7337

Type:

single initiation site

Name:

S100G_1

Description:

S100 calcium binding protein G

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	X	12,808,269 - 12,808,329	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000032533	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00040014312	UniProtKB/TrEMBL
	ENSCAFG00845030790	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000046135.3	UniProtKB/TrEMBL
	ENSCAFT00040026382.1	UniProtKB/TrEMBL
	ENSCAFT00845054733.1	UniProtKB/TrEMBL
Gene3D-CATH	EF-hand	UniProtKB/TrEMBL
InterPro	EF-hand-dom_pair	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_dom	UniProtKB/TrEMBL
	S-100_dom	UniProtKB/TrEMBL
	S100/CaBP-9k_CS	UniProtKB/TrEMBL
	S100_Ca-bd_sub	UniProtKB/TrEMBL
KEGG Report	cfa:607826	UniProtKB/TrEMBL
NCBI Gene	S100G	ENTREZGENE
PANTHER	PTHR11639:SF73	UniProtKB/TrEMBL
	S100 CALCIUM-BINDING PROTEIN	UniProtKB/TrEMBL
Pfam	EF-hand_1	UniProtKB/TrEMBL
	S_100	UniProtKB/TrEMBL
PROSITE	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
	S100_CABP	UniProtKB/TrEMBL
SMART	EFh	UniProtKB/TrEMBL
	S_100	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47473	UniProtKB/TrEMBL
UniProt	A0A8C0SKA9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3QAY5_CANLF	UniProtKB/TrEMBL
	A0A8P0SRB1_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:49688	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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