DDX1 (DEAD-box helicase 1) - Rat Genome Database

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Gene: DDX1 (DEAD-box helicase 1) Pan paniscus
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Symbol: DDX1
Name: DEAD-box helicase 1
RGD ID: 12021599
Description: ENCODES a protein that exhibits ATP binding (inferred); chromatin binding (inferred); DNA binding (inferred); INVOLVED IN response to exogenous dsRNA (ortholog); response to virus (ortholog); ASSOCIATED WITH amenorrhea (ortholog); endometrial hyperplasia (ortholog); human immunodeficiency virus infectious disease (ortholog); FOUND IN cleavage body (inferred); cytoplasm (inferred); cytoplasmic stress granule (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-dependent RNA helicase DDX1; DEAD/H-box helicase 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212110,890,477 - 110,930,113 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A110,894,450 - 110,959,990 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A15,582,499 - 15,619,751 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A15,716,044 - 15,753,482 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A15,716,044 - 15,753,623 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DDX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212110,890,477 - 110,930,113 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A110,894,450 - 110,959,990 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A15,582,499 - 15,619,751 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A15,716,044 - 15,753,482 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A15,716,044 - 15,753,623 (+)Ensemblpanpan1.1panPan2
DDX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38215,591,868 - 15,631,101 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl215,591,178 - 15,634,346 (+)EnsemblGRCh38hg38GRCh38
GRCh37215,731,992 - 15,771,225 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36215,649,221 - 15,688,676 (+)NCBINCBI36Build 36hg18NCBI36
Build 34215,682,367 - 15,721,823NCBI
Celera215,649,490 - 15,688,945 (+)NCBICelera
Cytogenetic Map2p24.3NCBI
HuRef215,583,004 - 15,622,496 (+)NCBIHuRef
CHM1_1215,661,598 - 15,701,093 (+)NCBICHM1_1
T2T-CHM13v2.0215,623,489 - 15,662,692 (+)NCBIT2T-CHM13v2.0
Ddx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391213,269,308 - 13,299,175 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1213,266,974 - 13,299,214 (-)EnsemblGRCm39 Ensembl
GRCm381213,219,307 - 13,249,174 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1213,216,973 - 13,249,213 (-)EnsemblGRCm38mm10GRCm38
MGSCv371213,226,113 - 13,255,980 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361213,245,295 - 13,275,162 (-)NCBIMGSCv36mm8
Celera1213,565,291 - 13,593,111 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map126.4NCBI
Ddx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8641,725,365 - 41,756,236 (-)NCBIGRCr8
mRatBN7.2635,996,469 - 36,027,340 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl635,996,469 - 36,027,365 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx636,308,721 - 36,339,592 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0636,623,377 - 36,654,248 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0636,091,437 - 36,122,515 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0638,422,892 - 38,453,762 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl638,422,888 - 38,453,797 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0647,188,697 - 47,219,567 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4636,794,602 - 36,825,473 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1636,812,356 - 36,818,005 (-)NCBI
Celera635,359,044 - 35,389,916 (-)NCBICelera
Cytogenetic Map6q15NCBI
Ddx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554879,085,918 - 9,119,979 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554879,085,950 - 9,117,599 (+)NCBIChiLan1.0ChiLan1.0
DDX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11711,432,060 - 11,467,000 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1711,432,136 - 11,466,990 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1711,375,128 - 11,409,962 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01711,559,789 - 11,594,731 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1711,559,798 - 11,594,727 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11711,419,496 - 11,454,379 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01711,429,814 - 11,464,805 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01711,454,120 - 11,488,966 (+)NCBIUU_Cfam_GSD_1.0
Ddx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629255,920,933 - 55,954,651 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649314,884,442 - 14,918,823 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649314,884,532 - 14,918,621 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3121,818,406 - 121,856,604 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13121,818,400 - 121,856,667 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23130,448,196 - 130,480,756 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DDX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11492,007,446 - 92,045,414 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1492,007,036 - 92,045,190 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604520,189,540 - 20,227,199 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624865898,850 - 928,091 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624865898,850 - 927,375 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003826983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000031068   ⟹   ENSPPAP00000008432
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A15,716,044 - 15,753,623 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000031075   ⟹   ENSPPAP00000008439
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A15,716,494 - 15,753,277 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000031079   ⟹   ENSPPAP00000008443
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A15,719,716 - 15,752,492 (+)Ensembl
RefSeq Acc Id: XM_003826983   ⟹   XP_003827031
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212110,890,477 - 110,930,113 (-)NCBI
NHGRI_mPanPan12A110,894,450 - 110,958,369 (-)NCBI
Mhudiblu_PPA_v02A15,582,499 - 15,619,751 (+)NCBI
PanPan1.12A15,716,044 - 15,753,482 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003827031 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000008432
  ENSPPAP00000008432.1
  ENSPPAP00000008439.1
  ENSPPAP00000008443.1
RefSeq Acc Id: XP_003827031   ⟸   XM_003826983
- UniProtKB: A0A2R8ZXC2 (UniProtKB/TrEMBL),   A0A2R8ZZP8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000008439   ⟸   ENSPPAT00000031075
Ensembl Acc Id: ENSPPAP00000008443   ⟸   ENSPPAT00000031079
Ensembl Acc Id: ENSPPAP00000008432   ⟸   ENSPPAT00000031068

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027432 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000031068.1 UniProtKB/TrEMBL
  ENSPPAT00000031075.1 UniProtKB/TrEMBL
  ENSPPAT00000031079.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RNA_helicase_DEAD_Q_motif UniProtKB/TrEMBL
  SPRY_dom UniProtKB/TrEMBL
KEGG Report pps:100975496 UniProtKB/TrEMBL
NCBI Gene DDX1 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE DBP3 UniProtKB/TrEMBL
  ATP-DEPENDENT RNA HELICASE DDX1 UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  Q_MOTIF UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A2R8ZTZ1_PANPA UniProtKB/TrEMBL
  A0A2R8ZXC2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZZP8 ENTREZGENE, UniProtKB/TrEMBL