NUBP2 (NUBP iron-sulfur cluster assembly factor 2, cytosolic) - Rat Genome Database

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Gene: NUBP2 (NUBP iron-sulfur cluster assembly factor 2, cytosolic) Pan paniscus
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Symbol: NUBP2
Name: NUBP iron-sulfur cluster assembly factor 2, cytosolic
RGD ID: 11994908
Description: ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); ATP binding (inferred); ATP-dependent FeS chaperone activity (inferred); INVOLVED IN iron-sulfur cluster assembly (inferred); PARTICIPATES IN cytosolic iron-sulfur cluster protein assembly pathway; ASSOCIATED WITH developmental and epileptic encephalopathy 1 (ortholog); epilepsy (ortholog); idiopathic generalized epilepsy (ortholog); FOUND IN cytosol (inferred); nucleus (inferred); spindle pole centrosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cytosolic Fe-S cluster assembly factor NUBP2; nucleotide binding protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,048,898 - 2,055,881 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1165,830,832 - 5,837,318 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v016405,264 - 411,626 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1161,836,186 - 1,842,752 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NUBP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,048,898 - 2,055,881 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1165,830,832 - 5,837,318 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v016405,264 - 411,626 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1161,836,186 - 1,842,752 (+)NCBIpanpan1.1PanPan1.1panPan2
NUBP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38161,782,960 - 1,789,186 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl161,782,932 - 1,789,186 (+)EnsemblGRCh38hg38GRCh38
GRCh37161,832,961 - 1,839,187 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,772,960 - 1,779,187 (+)NCBINCBI36Build 36hg18NCBI36
Build 34161,772,959 - 1,779,187NCBI
Celera162,045,211 - 2,051,474 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef161,755,830 - 1,762,093 (+)NCBIHuRef
CHM1_1161,832,881 - 1,839,140 (+)NCBICHM1_1
T2T-CHM13v2.0161,798,796 - 1,805,026 (+)NCBIT2T-CHM13v2.0
Nubp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391725,101,585 - 25,105,423 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1725,101,585 - 25,105,323 (-)EnsemblGRCm39 Ensembl
GRCm381724,882,611 - 24,886,350 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,882,611 - 24,886,349 (-)EnsemblGRCm38mm10GRCm38
MGSCv371725,019,556 - 25,023,295 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361724,610,217 - 24,613,930 (-)NCBIMGSCv36mm8
Celera1725,409,418 - 25,413,163 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.53NCBI
Nubp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,407,743 - 14,411,428 (-)NCBIGRCr8
mRatBN7.21013,903,224 - 13,906,928 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,903,224 - 13,906,969 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,650,265 - 18,653,975 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01018,139,125 - 18,142,835 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,638,342 - 13,642,052 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,244,201 - 14,247,930 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,244,203 - 14,247,886 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01014,060,217 - 14,063,902 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41014,131,309 - 14,134,994 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11014,131,309 - 14,134,994 (-)NCBI
Celera1013,582,432 - 13,586,117 (-)NCBICelera
Cytogenetic Map10q12NCBI
Nubp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,483,549 - 15,486,741 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,482,916 - 15,486,830 (-)NCBIChiLan1.0ChiLan1.0
NUBP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,119,332 - 39,121,869 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,119,337 - 39,122,370 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,358,237 - 40,360,777 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,435,772 - 39,438,315 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl639,435,775 - 39,438,277 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1639,112,469 - 39,115,008 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,085,049 - 39,087,589 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,563,512 - 39,566,056 (-)NCBIUU_Cfam_GSD_1.0
Nubp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,487,638 - 104,501,366 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366942,208,518 - 2,211,653 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366942,208,102 - 2,211,910 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUBP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl340,178,417 - 40,186,551 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1340,178,417 - 40,184,646 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,626,428 - 41,633,605 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NUBP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.151,687,972 - 1,697,559 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl51,691,565 - 1,697,562 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606829,388,788 - 29,394,690 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nubp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624913465,894 - 469,389 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624913465,097 - 469,663 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_003807607   ⟹   XP_003807655
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2182,048,898 - 2,055,881 (+)NCBI
NHGRI_mPanPan1165,830,832 - 5,837,318 (+)NCBI
Mhudiblu_PPA_v016405,264 - 411,622 (+)NCBI
PanPan1.1161,836,186 - 1,842,752 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008959745   ⟹   XP_008957993
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2182,049,758 - 2,055,881 (+)NCBI
NHGRI_mPanPan1165,831,236 - 5,837,318 (+)NCBI
Mhudiblu_PPA_v016406,280 - 411,626 (+)NCBI
PanPan1.1161,837,404 - 1,842,752 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008959746   ⟹   XP_008957994
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2182,049,231 - 2,055,881 (+)NCBI
NHGRI_mPanPan1165,830,994 - 5,837,318 (+)NCBI
Mhudiblu_PPA_v016405,293 - 411,173 (+)NCBI
PanPan1.1161,836,187 - 1,842,752 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034939618   ⟹   XP_034795509
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2182,050,596 - 2,055,881 (+)NCBI
NHGRI_mPanPan1165,832,029 - 5,837,318 (+)NCBI
Mhudiblu_PPA_v016406,349 - 411,173 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003807655 (Get FASTA)   NCBI Sequence Viewer  
  XP_008957993 (Get FASTA)   NCBI Sequence Viewer  
  XP_008957994 (Get FASTA)   NCBI Sequence Viewer  
  XP_034795509 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000012888.1
  ENSPPAP00000012901
  ENSPPAP00000012901.1
RefSeq Acc Id: XP_008957994   ⟸   XM_008959746
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AB88 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003807655   ⟸   XM_003807607
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008957993   ⟸   XM_008959745
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034795509   ⟸   XM_034939618
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AB88 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029613 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000035555.1 UniProtKB/TrEMBL
  ENSPPAT00000035568.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro Mrp/NBP35_ATP-bd UniProtKB/TrEMBL
  Mrp_CS UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  YlxH/NBP35 UniProtKB/TrEMBL
NCBI Gene NUBP2 ENTREZGENE
PANTHER CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2 UniProtKB/TrEMBL
  PTHR23264 UniProtKB/TrEMBL
Pfam ParA UniProtKB/TrEMBL
PROSITE MRP UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9A6G9_PANPA UniProtKB/TrEMBL
  A0A2R9AB88 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-12-21 NUBP2  NUBP iron-sulfur cluster assembly factor 2, cytosolic  NUBP2  nucleotide binding protein 2  Symbol and/or name change 5135510 APPROVED