ACKR3 (atypical chemokine receptor 3) - Rat Genome Database

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Gene: ACKR3 (atypical chemokine receptor 3) Pan paniscus
Analyze
Symbol: ACKR3
Name: atypical chemokine receptor 3
RGD ID: 11971495
Description: ENCODES a protein that exhibits C-X-C chemokine binding (inferred); C-X-C chemokine receptor activity (inferred); chemokine binding (inferred); INVOLVED IN negative regulation of cell population proliferation (ortholog); positive regulation of ERK1 and ERK2 cascade (ortholog); positive regulation of mesenchymal stem cell migration (ortholog); ASSOCIATED WITH Bethlem Myopathy 1A (ortholog); carcinoma (ortholog); clear cell renal cell carcinoma (ortholog); FOUND IN cell surface (inferred); clathrin-coated pit (inferred); endosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: chemokine (C-X-C motif) receptor 7; CXCR7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213139,194,667 - 139,209,073 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B139,209,625 - 139,224,039 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B123,795,664 - 123,810,067 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B242,653,738 - 242,668,063 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B242,666,173 - 242,667,261 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
ACKR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213139,194,667 - 139,209,073 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B139,209,625 - 139,224,039 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B123,795,664 - 123,810,067 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B242,653,738 - 242,668,063 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B242,666,173 - 242,667,261 (+)Ensemblpanpan1.1panPan2
ACKR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382236,537,122 - 236,582,354 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2236,567,787 - 236,582,354 (+)EnsemblGRCh38hg38GRCh38
GRCh372237,478,468 - 237,490,997 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,143,119 - 237,155,736 (+)NCBINCBI36Build 36hg18NCBI36
Build 342237,260,442 - 237,272,991NCBI
Celera2231,191,070 - 231,203,687 (+)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2229,272,353 - 229,284,798 (+)NCBIHuRef
CHM1_12237,484,219 - 237,496,832 (+)NCBICHM1_1
T2T-CHM13v2.02237,027,450 - 237,072,880 (+)NCBIT2T-CHM13v2.0
Ackr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39190,131,702 - 90,143,446 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl190,131,702 - 90,144,473 (+)EnsemblGRCm39 Ensembl
GRCm38190,203,980 - 90,215,724 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl190,203,980 - 90,216,751 (+)EnsemblGRCm38mm10GRCm38
MGSCv37192,100,578 - 92,112,863 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36192,035,174 - 92,047,459 (+)NCBIMGSCv36mm8
Celera193,147,393 - 93,159,682 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map145.28NCBI
Ackr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8998,247,300 - 98,258,877 (+)NCBIGRCr8
mRatBN7.2990,799,682 - 90,811,246 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl990,799,686 - 90,811,237 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx999,226,229 - 99,237,752 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09104,362,114 - 104,373,635 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09102,727,673 - 102,739,194 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0997,355,881 - 97,367,455 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl997,355,924 - 97,367,445 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0997,046,816 - 97,058,382 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4989,343,528 - 89,355,053 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1989,548,296 - 89,559,818 (+)NCBI
Celera988,347,205 - 88,358,728 (+)NCBICelera
Cytogenetic Map9q36NCBI
Ackr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955453195,346 - 218,034 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955453195,346 - 218,034 (-)NCBIChiLan1.0ChiLan1.0
ACKR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12547,327,921 - 47,339,632 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2547,327,963 - 47,339,622 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2547,833,792 - 47,835,768 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02547,675,583 - 47,687,325 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2547,675,593 - 47,687,321 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12547,593,385 - 47,595,361 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02547,386,571 - 47,388,546 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02547,617,367 - 47,619,344 (+)NCBIUU_Cfam_GSD_1.0
Ackr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303189,351,726 - 189,380,121 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365251,559,575 - 1,570,679 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACKR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15136,370,530 - 136,382,553 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115136,370,457 - 136,382,559 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215150,847,155 - 150,859,228 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACKR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110122,558,998 - 122,573,747 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10122,571,853 - 122,572,941 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604076,827,681 - 76,842,164 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ackr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248472,189,257 - 2,200,352 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248472,189,167 - 2,200,355 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000014667   ⟹   ENSPPAP00000003168
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B242,666,173 - 242,667,261 (+)Ensembl
RefSeq Acc Id: XM_003813113   ⟹   XP_003813161
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213139,196,288 - 139,209,073 (+)NCBI
NHGRI_mPanPan12B139,211,713 - 139,224,039 (+)NCBI
Mhudiblu_PPA_v02B123,797,740 - 123,810,067 (+)NCBI
PanPan1.12B242,655,607 - 242,668,063 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003813115   ⟹   XP_003813163
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213139,194,667 - 139,209,073 (+)NCBI
NHGRI_mPanPan12B139,209,625 - 139,224,039 (+)NCBI
Mhudiblu_PPA_v02B123,795,664 - 123,810,067 (+)NCBI
PanPan1.12B242,653,738 - 242,668,063 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024928013   ⟹   XP_024783781
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213139,195,449 - 139,209,073 (+)NCBI
NHGRI_mPanPan12B139,210,415 - 139,224,039 (+)NCBI
Mhudiblu_PPA_v02B123,795,971 - 123,810,067 (+)NCBI
PanPan1.12B242,654,484 - 242,668,063 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063595321   ⟹   XP_063451391
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213139,195,450 - 139,209,073 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003813161 (Get FASTA)   NCBI Sequence Viewer  
  XP_003813163 (Get FASTA)   NCBI Sequence Viewer  
  XP_024783781 (Get FASTA)   NCBI Sequence Viewer  
  XP_063451391 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000003168
  ENSPPAP00000003168.1
RefSeq Acc Id: XP_003813163   ⟸   XM_003813115
- UniProtKB: A0A2R8ZE81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003813161   ⟸   XM_003813113
- UniProtKB: A0A2R8ZE81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024783781   ⟸   XM_024928013
- UniProtKB: A0A2R8ZE81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000003168   ⟸   ENSPPAT00000014667
RefSeq Acc Id: XP_063451391   ⟸   XM_063595321
- UniProtKB: A0A2R8ZE81 (UniProtKB/TrEMBL)

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000013418 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000014667.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro ACKR3 UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  GPER1-like UniProtKB/TrEMBL
KEGG Report pps:100980618 UniProtKB/TrEMBL
NCBI Gene ACKR3 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  RDC1ORPHANR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A2R8ZE81 ENTREZGENE, UniProtKB/TrEMBL