ACKR3 (atypical chemokine receptor 3) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: ACKR3 (atypical chemokine receptor 3) Sus scrofa
Analyze
Symbol: ACKR3
Name: atypical chemokine receptor 3
RGD ID: 14053692
Description: ENCODES a protein that exhibits C-X-C chemokine binding (inferred); C-X-C chemokine receptor activity (inferred); coreceptor activity (inferred); INVOLVED IN negative regulation of cell population proliferation (ortholog); positive regulation of ERK1 and ERK2 cascade (ortholog); positive regulation of mesenchymal stem cell migration (ortholog); ASSOCIATED WITH Bethlem Myopathy 1 (ortholog); carcinoma (ortholog); Colorectal Neoplasms (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: chemokine (C-X-C motif) receptor 7; CXCR7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15136,370,530 - 136,382,559 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115136,370,457 - 136,382,559 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215150,847,155 - 150,859,228 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
ACKR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15136,370,530 - 136,382,559 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115136,370,457 - 136,382,559 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215150,847,155 - 150,859,228 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACKR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2236,567,787 - 236,582,354 (+)EnsemblGRCh38hg38GRCh38
GRCh382236,537,131 - 236,582,358 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372237,478,468 - 237,490,997 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,143,119 - 237,155,736 (+)NCBINCBI36hg18NCBI36
Build 342237,260,442 - 237,272,991NCBI
Celera2231,191,070 - 231,203,687 (+)NCBI
Cytogenetic Map2q37.3NCBI
HuRef2229,272,353 - 229,284,798 (+)NCBIHuRef
CHM1_12237,484,219 - 237,496,832 (+)NCBICHM1_1
Ackr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39190,131,702 - 90,143,446 (+)NCBIGRCm39mm39
GRCm39 Ensembl190,131,702 - 90,144,473 (+)Ensembl
GRCm38190,203,980 - 90,215,724 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl190,203,980 - 90,216,751 (+)EnsemblGRCm38mm10GRCm38
MGSCv37192,100,578 - 92,112,863 (+)NCBIGRCm37mm9NCBIm37
MGSCv36192,035,174 - 92,047,459 (+)NCBImm8
Celera193,147,393 - 93,159,682 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map145.28NCBI
Ackr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2990,799,682 - 90,811,246 (+)NCBI
Rnor_6.0 Ensembl997,355,924 - 97,367,445 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0997,355,881 - 97,367,455 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0997,046,816 - 97,058,382 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4989,343,528 - 89,355,053 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1989,548,296 - 89,559,818 (+)NCBI
Celera988,347,205 - 88,358,728 (+)NCBICelera
Cytogenetic Map9q36NCBI
Ackr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955453195,346 - 218,034 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955453195,346 - 218,034 (-)NCBIChiLan1.0ChiLan1.0
ACKR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B242,653,738 - 242,668,063 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B242,666,173 - 242,667,261 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B123,795,664 - 123,810,067 (+)NCBIMhudiblu_PPA_v0panPan3
ACKR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2547,327,963 - 47,339,622 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12547,327,921 - 47,339,632 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ackr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365251,559,575 - 1,570,679 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACKR3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110122,558,998 - 122,573,747 (+)NCBI
ChlSab1.1 Ensembl10122,571,853 - 122,572,941 (+)Ensembl
Ackr3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248472,189,167 - 2,200,355 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1 1 2 2
Low 9 3 3 4 2 23 1 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017775   ⟹   ENSSSCP00000017294
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15136,370,530 - 136,382,559 (+)Ensembl
RefSeq Acc Id: XM_003133759   ⟹   XP_003133807
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115136,370,457 - 136,382,559 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003133807 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003133807   ⟸   XM_003133759
- UniProtKB: F1SM08 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000017294   ⟸   ENSSSCT00000017775
Protein Domains
G_PROTEIN_RECEP_F1_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016322 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070007601 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000017294 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070012124 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017775 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070014673 UniProtKB/TrEMBL
InterPro ACKR3 UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
KEGG Report ssc:100515346 UniProtKB/TrEMBL
NCBI Gene ACKR3 ENTREZGENE
PANTHER PTHR10489:SF931 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  RDC1ORPHANR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
UniProt A0A4X1T9Z1_PIG UniProtKB/TrEMBL
  F1SM08 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:96017 ENTREZGENE