TULP4 (TUB like protein 4) - Rat Genome Database

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Gene: TULP4 (TUB like protein 4) Pan paniscus
Analyze
Symbol: TULP4
Name: TUB like protein 4
RGD ID: 11962435
Description: INVOLVED IN protein ubiquitination (inferred); ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (ortholog); chromosome 6q24-q25 deletion syndrome (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tubby like protein 4; tubby-related protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25178,348,549 - 178,620,918 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16176,252,142 - 176,524,790 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06156,134,524 - 156,406,899 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16161,227,355 - 161,421,659 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6161,227,355 - 161,416,546 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
TULP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25178,348,549 - 178,620,918 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16176,252,142 - 176,524,790 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06156,134,524 - 156,406,899 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16161,227,355 - 161,421,659 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6161,227,355 - 161,416,546 (+)Ensemblpanpan1.1panPan2
TULP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386158,232,195 - 158,511,828 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6158,232,236 - 158,511,828 (+)EnsemblGRCh38hg38GRCh38
GRCh376158,733,497 - 158,932,860 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366158,653,680 - 158,852,848 (+)NCBINCBI36Build 36hg18NCBI36
Build 346158,704,100 - 158,903,263NCBI
Celera6159,381,741 - 159,580,886 (+)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6156,205,571 - 156,404,118 (+)NCBIHuRef
CHM1_16158,996,493 - 159,195,628 (+)NCBICHM1_1
T2T-CHM13v2.06159,476,584 - 159,756,806 (+)NCBIT2T-CHM13v2.0
Tulp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39176,156,528 - 6,290,912 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl176,156,712 - 6,301,403 (+)EnsemblGRCm39 Ensembl
GRCm38176,106,253 - 6,240,637 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl176,106,437 - 6,251,128 (+)EnsemblGRCm38mm10GRCm38
MGSCv37176,106,830 - 6,240,637 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36176,095,226 - 6,197,103 (+)NCBIMGSCv36mm8
Celera176,644,957 - 6,763,753 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map173.72NCBI
Tulp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8149,082,492 - 49,218,262 (+)NCBIGRCr8
mRatBN7.2146,682,416 - 46,813,167 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl146,682,863 - 46,809,688 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx147,259,725 - 47,357,561 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0153,246,987 - 53,344,818 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0147,335,153 - 47,432,988 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,002,928 - 47,128,114 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,032,113 - 47,127,035 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0148,306,876 - 48,435,206 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4140,912,287 - 41,010,505 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera142,399,937 - 42,497,708 (+)NCBICelera
Cytogenetic Map1q11NCBI
Tulp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554393,940,098 - 4,119,874 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554393,935,422 - 4,121,780 (-)NCBIChiLan1.0ChiLan1.0
TULP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1147,727,642 - 47,952,818 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl147,791,993 - 47,951,710 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha148,570,799 - 48,797,892 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0147,913,821 - 48,141,165 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl147,913,845 - 48,139,520 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1147,791,982 - 48,015,516 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0147,663,797 - 47,886,197 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0148,223,163 - 48,445,777 (+)NCBIUU_Cfam_GSD_1.0
Tulp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946142,838,786 - 143,003,641 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648910,092,739 - 10,252,154 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648910,090,759 - 10,255,634 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TULP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.118,650,811 - 8,891,596 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2110,659,274 - 10,681,041 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TULP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11385,881,735 - 86,088,074 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1385,883,698 - 86,085,894 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604058,185,297 - 58,463,770 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tulp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249291,098,801 - 1,253,891 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249291,095,164 - 1,317,623 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000054322   ⟹   ENSPPAP00000031458
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6161,227,355 - 161,416,546 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000054327   ⟹   ENSPPAP00000031463
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6161,229,365 - 161,416,546 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000054330   ⟹   ENSPPAP00000031466
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6161,229,365 - 161,416,452 (+)Ensembl
RefSeq Acc Id: XM_034963151   ⟹   XP_034819042
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25178,348,551 - 178,620,918 (+)NCBI
NHGRI_mPanPan16176,252,145 - 176,524,790 (+)NCBI
Mhudiblu_PPA_v06156,134,524 - 156,406,899 (+)NCBI
RefSeq Acc Id: XM_034963152   ⟹   XP_034819043
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25178,348,549 - 178,620,918 (+)NCBI
NHGRI_mPanPan16176,252,142 - 176,524,790 (+)NCBI
Mhudiblu_PPA_v06156,134,524 - 156,406,899 (+)NCBI
RefSeq Acc Id: XM_034963153   ⟹   XP_034819044
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25178,421,235 - 178,620,918 (+)NCBI
NHGRI_mPanPan16176,324,816 - 176,524,790 (+)NCBI
Mhudiblu_PPA_v06156,207,200 - 156,406,899 (+)NCBI
RefSeq Acc Id: XM_034963155   ⟹   XP_034819046
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25178,348,552 - 178,620,918 (+)NCBI
NHGRI_mPanPan16176,252,149 - 176,524,790 (+)NCBI
Mhudiblu_PPA_v06156,134,536 - 156,403,952 (+)NCBI
RefSeq Acc Id: XM_034963156   ⟹   XP_034819047
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25178,348,551 - 178,620,918 (+)NCBI
NHGRI_mPanPan16176,252,145 - 176,524,790 (+)NCBI
Mhudiblu_PPA_v06156,134,524 - 156,406,899 (+)NCBI
RefSeq Acc Id: XM_055114281   ⟹   XP_054970256
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25178,348,551 - 178,620,918 (+)NCBI
NHGRI_mPanPan16176,252,161 - 176,524,790 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034819043   ⟸   XM_034963152
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034819042   ⟸   XM_034963151
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034819047   ⟸   XM_034963156
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034819046   ⟸   XM_034963155
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034819044   ⟸   XM_034963153
- Peptide Label: isoform X1
RefSeq Acc Id: ENSPPAP00000031463   ⟸   ENSPPAT00000054327
RefSeq Acc Id: ENSPPAP00000031458   ⟸   ENSPPAT00000054322
RefSeq Acc Id: ENSPPAP00000031466   ⟸   ENSPPAT00000054330
RefSeq Acc Id: XP_054970256   ⟸   XM_055114281
- Peptide Label: isoform X1
Protein Domains
SOCS box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038644 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000054322.1 UniProtKB/TrEMBL
  ENSPPAT00000054327.1 UniProtKB/TrEMBL
  ENSPPAT00000054330.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro SOCS_box UniProtKB/TrEMBL
  Tubby-like_C UniProtKB/TrEMBL
  Tubby_C UniProtKB/TrEMBL
  Tumour_necrosis_fac-like_dom UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene TULP4 ENTREZGENE
PANTHER TUBBY-RELATED UniProtKB/TrEMBL
  TUBBY-RELATED PROTEIN 4 UniProtKB/TrEMBL
Pfam SOCS_box UniProtKB/TrEMBL
  Tub UniProtKB/TrEMBL
PRINTS SUPERTUBBY UniProtKB/TrEMBL
PROSITE SOCS UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART SOCS_box UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF49842 UniProtKB/TrEMBL
  SSF50978 UniProtKB/TrEMBL
  SSF54518 UniProtKB/TrEMBL
UniProt A0A2R9BP67_PANPA UniProtKB/TrEMBL
  A0A2R9BSP4_PANPA UniProtKB/TrEMBL
  A0A2R9BSQ0_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-16 TULP4  TUB like protein 4    tubby like protein 4  Symbol and/or name change 5135510 APPROVED