TFE3 (transcription factor binding to IGHM enhancer 3) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: TFE3 (transcription factor binding to IGHM enhancer 3) Pan paniscus
Analyze
Symbol: TFE3
Name: transcription factor binding to IGHM enhancer 3
RGD ID: 11961298
Description: ENCODES a protein that exhibits E-box binding (ortholog); protein heterodimerization activity (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN negative regulation of cold-induced thermogenesis (ortholog); positive regulation of brown fat cell differentiation (ortholog); positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH autistic disorder (ortholog); congenital disorder of glycosylation type IIm (ortholog); genetic disease (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor E3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X50,518,538 - 50,533,445 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X50,521,917 - 50,536,666 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X41,326,802 - 41,341,574 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X49,182,795 - 49,197,194 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX49,182,795 - 49,197,194 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TFE3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X50,518,538 - 50,533,445 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X50,521,917 - 50,536,666 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X41,326,802 - 41,341,574 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X49,182,795 - 49,197,194 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX49,182,795 - 49,197,194 (-)Ensemblpanpan1.1panPan2
TFE3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X49,028,726 - 49,043,357 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX49,028,726 - 49,043,410 (-)EnsemblGRCh38hg38GRCh38
GRCh37X48,886,237 - 48,900,883 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,771,186 - 48,787,934 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X48,642,489 - 48,657,239NCBI
CeleraX52,763,508 - 52,778,256 (+)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX46,544,091 - 46,558,358 (-)NCBIHuRef
CHM1_1X48,917,574 - 48,932,321 (-)NCBICHM1_1
T2T-CHM13v2.0X48,440,314 - 48,454,961 (-)NCBIT2T-CHM13v2.0
Tfe3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,628,769 - 7,641,441 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX7,628,799 - 7,641,441 (+)EnsemblGRCm39 Ensembl
GRCm38X7,762,530 - 7,775,202 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX7,762,560 - 7,775,202 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X7,339,787 - 7,352,328 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X6,919,676 - 6,932,158 (+)NCBIMGSCv36mm8
CeleraX3,695,480 - 3,708,004 (-)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.5NCBI
Tfe3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X17,401,466 - 17,414,829 (-)NCBIGRCr8
mRatBN7.2X14,729,547 - 14,742,830 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX14,729,550 - 14,742,571 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX19,543,279 - 19,556,535 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X20,526,577 - 20,539,833 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X16,791,746 - 16,805,003 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X15,574,579 - 15,587,826 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,575,934 - 15,587,419 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X16,355,812 - 16,369,002 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,768,875 - 26,781,006 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX14,814,215 - 14,827,305 (-)NCBICelera
Cytogenetic MapXq12NCBI
Tfe3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955543547,037 - 561,073 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955543547,037 - 561,073 (-)NCBIChiLan1.0ChiLan1.0
TFE3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X42,181,639 - 42,192,709 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX42,183,037 - 42,193,892 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX16,557,254 - 16,568,302 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X42,317,881 - 42,328,931 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX42,317,905 - 42,328,969 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X42,304,191 - 42,315,238 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X42,291,847 - 42,302,895 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X42,386,591 - 42,397,641 (-)NCBIUU_Cfam_GSD_1.0
Tfe3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X34,693,183 - 34,705,282 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936721933,404 - 945,725 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936721933,572 - 945,717 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFE3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX43,100,032 - 43,116,227 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X43,100,375 - 43,116,377 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X47,948,307 - 47,964,209 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TFE3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X46,141,377 - 46,155,445 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX46,140,543 - 46,155,372 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607611,655,554 - 11,669,637 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tfe3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624893803,717 - 817,705 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624893803,717 - 817,700 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000033924   ⟹   ENSPPAP00000011269
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX49,182,795 - 49,197,194 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000033930   ⟹   ENSPPAP00000011275
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX49,184,224 - 49,196,903 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000033932   ⟹   ENSPPAP00000011277
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX49,184,224 - 49,196,903 (-)Ensembl
RefSeq Acc Id: XM_003807242   ⟹   XP_003807290
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X50,518,538 - 50,533,445 (-)NCBI
NHGRI_mPanPan1X50,521,917 - 50,536,666 (-)NCBI
Mhudiblu_PPA_v0X41,326,802 - 41,341,574 (-)NCBI
PanPan1.1X49,182,795 - 49,197,194 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003807290 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000011269.1
  ENSPPAP00000011275.1
  ENSPPAP00000011277.1
RefSeq Acc Id: XP_003807290   ⟸   XM_003807242
- UniProtKB: A0A2R9A329 (UniProtKB/TrEMBL),   A0A2R9A6G5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000011275   ⟸   ENSPPAT00000033930
Ensembl Acc Id: ENSPPAP00000011277   ⟸   ENSPPAT00000033932
Ensembl Acc Id: ENSPPAP00000011269   ⟸   ENSPPAT00000033924
Protein Domains
bHLH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000028832 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000033924.1 UniProtKB/TrEMBL
  ENSPPAT00000033930.1 UniProtKB/TrEMBL
  ENSPPAT00000033932.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  MiT/TFE_C UniProtKB/TrEMBL
  MiT/TFE_N UniProtKB/TrEMBL
  TFE3 UniProtKB/TrEMBL
KEGG Report pps:100984828 UniProtKB/TrEMBL
NCBI Gene TFE3 ENTREZGENE
PANTHER MIP04163P UniProtKB/TrEMBL
  PTHR45776:SF3 UniProtKB/TrEMBL
Pfam DUF3371 UniProtKB/TrEMBL
  HLH UniProtKB/TrEMBL
  MITF_TFEB_C_3_N UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
UniProt A0A2R9A1Y5_PANPA UniProtKB/TrEMBL
  A0A2R9A329 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A6G5 ENTREZGENE, UniProtKB/TrEMBL