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Gene: TFE3 (transcription factor binding to IGHM enhancer 3) Homo sapiens
Symbol: TFE3
Name: transcription factor binding to IGHM enhancer 3
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and transcription regulatory region DNA binding activity. Involved in positive regulation of cell adhesion and positive regulation of transcription by RNA polymerase II. Localizes to the cytosol and nucleoplasm. Implicated in renal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bHLHe33; class E basic helix-loop-helix protein 33; RCCP2; RCCX1; TFEA; transcription factor E family, member A; transcription factor E3; Transcription factor for IgH enhancer; transcription factor for immunoglobulin heavy-chain enhancer 3
Mus musculus (house mouse) : Tfe3 (transcription factor E3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tfe3 (transcription factor binding to IGHM enhancer 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tfe3 (transcription factor binding to IGHM enhancer 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TFE3 (transcription factor binding to IGHM enhancer 3)
Canis lupus familiaris (dog) : TFE3 (transcription factor binding to IGHM enhancer 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tfe3 (transcription factor binding to IGHM enhancer 3)
Sus scrofa (pig) : TFE3 (transcription factor binding to IGHM enhancer 3)
Chlorocebus sabaeus (green monkey) : TFE3 (transcription factor binding to IGHM enhancer 3)
Heterocephalus glaber (naked mole-rat) : Tfe3 (transcription factor binding to IGHM enhancer 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX49,028,726 - 49,043,410 (-)Ensembl
GRCh38X49,028,726 - 49,043,357 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X48,886,237 - 48,900,990 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,771,186 - 48,787,934 (-)NCBINCBI36hg18NCBI36
Build 34X48,642,489 - 48,657,239NCBI
CeleraX52,763,508 - 52,778,256 (+)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX46,544,091 - 46,558,358 (-)NCBIHuRef
CHM1_1X48,917,569 - 48,932,374 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on TFE3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1351703
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.