CALML4 (calmodulin like 4) - Rat Genome Database

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Gene: CALML4 (calmodulin like 4) Pan paniscus
Analyze
Symbol: CALML4
Name: calmodulin like 4
RGD ID: 11936848
Description: ENCODES a protein that exhibits myosin head/neck binding (ortholog); INVOLVED IN brush border assembly (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); neuronal ceroid lipofuscinosis (ortholog); FOUND IN microvillus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: calmodulin-like protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21657,444,352 - 57,460,549 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11561,618,194 - 61,634,392 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01547,140,272 - 47,155,700 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11565,409,732 - 65,424,852 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1565,409,732 - 65,424,852 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CALML4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21657,444,352 - 57,460,549 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11561,618,194 - 61,634,392 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01547,140,272 - 47,155,700 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11565,409,732 - 65,424,852 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1565,409,732 - 65,424,852 (-)Ensemblpanpan1.1panPan2
CALML4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381568,190,705 - 68,206,110 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1568,190,705 - 68,206,079 (-)EnsemblGRCh38hg38GRCh38
GRCh371568,483,043 - 68,498,448 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361566,270,097 - 66,285,502 (-)NCBINCBI36Build 36hg18NCBI36
Build 341566,270,479 - 66,285,502NCBI
Celera1545,367,956 - 45,383,362 (-)NCBICelera
Cytogenetic Map15q23NCBI
HuRef1545,313,778 - 45,329,162 (-)NCBIHuRef
CHM1_11568,600,995 - 68,616,402 (-)NCBICHM1_1
T2T-CHM13v2.01566,009,455 - 66,024,859 (-)NCBIT2T-CHM13v2.0
Calml4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39962,765,068 - 62,783,203 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl962,765,362 - 62,783,203 (+)EnsemblGRCm39 Ensembl
GRCm38962,857,472 - 62,875,921 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl962,858,080 - 62,875,921 (+)EnsemblGRCm38mm10GRCm38
MGSCv37962,705,911 - 62,723,725 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36962,656,110 - 62,673,924 (+)NCBIMGSCv36mm8
Celera960,083,497 - 60,094,995 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map933.9NCBI
Calml4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8872,218,870 - 72,230,650 (+)NCBIGRCr8
mRatBN7.2863,323,426 - 63,335,234 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl863,323,351 - 63,335,234 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx868,838,506 - 68,850,149 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0867,110,960 - 67,122,603 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0864,980,956 - 64,992,609 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0867,753,279 - 67,765,359 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl867,753,279 - 67,765,358 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0867,482,026 - 67,494,105 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4867,007,122 - 67,018,886 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera862,738,382 - 62,750,146 (+)NCBICelera
Cytogenetic Map8q24NCBI
Calml4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554507,887,414 - 7,894,143 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554507,886,565 - 7,894,143 (+)NCBIChiLan1.0ChiLan1.0
CALML4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13032,234,879 - 32,244,321 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3032,235,091 - 32,240,008 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3032,169,539 - 32,179,258 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03032,430,743 - 32,440,471 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3032,430,780 - 32,435,698 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13032,359,011 - 32,368,754 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03032,420,957 - 32,430,694 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03032,666,809 - 32,676,532 (-)NCBIUU_Cfam_GSD_1.0
Calml4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640110,210,102 - 110,222,226 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647128,058,176 - 28,067,442 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647128,058,165 - 28,067,463 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CALML4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1166,083,629 - 166,099,593 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11166,089,583 - 166,099,794 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CALML4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12615,278,349 - 15,291,934 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666048126,176,796 - 126,188,708 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Calml4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247814,882,136 - 4,888,358 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247814,880,142 - 4,892,829 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000043059   ⟹   ENSPPAP00000020267
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1565,409,732 - 65,424,589 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000043066   ⟹   ENSPPAP00000020274
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1565,410,595 - 65,424,852 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000043073   ⟹   ENSPPAP00000020281
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1565,412,694 - 65,423,855 (-)Ensembl
RefSeq Acc Id: XM_003828012   ⟹   XP_003828060
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21657,444,352 - 57,460,549 (-)NCBI
NHGRI_mPanPan11561,618,194 - 61,634,392 (-)NCBI
Mhudiblu_PPA_v01547,140,272 - 47,155,700 (-)NCBI
PanPan1.11565,410,588 - 65,424,852 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008953352   ⟹   XP_008951600
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21657,444,352 - 57,460,549 (-)NCBI
NHGRI_mPanPan11561,618,194 - 61,634,392 (-)NCBI
Mhudiblu_PPA_v01547,140,272 - 47,155,700 (-)NCBI
PanPan1.11565,409,732 - 65,424,589 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008953353   ⟹   XP_008951601
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21657,444,352 - 57,459,042 (-)NCBI
NHGRI_mPanPan11561,618,194 - 61,632,885 (-)NCBI
Mhudiblu_PPA_v01547,140,272 - 47,155,700 (-)NCBI
PanPan1.11565,409,732 - 65,424,589 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008953354   ⟹   XP_008951602
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21657,444,352 - 57,459,051 (-)NCBI
NHGRI_mPanPan11561,618,194 - 61,632,894 (-)NCBI
Mhudiblu_PPA_v01547,140,272 - 47,155,700 (-)NCBI
PanPan1.11565,409,732 - 65,424,589 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003828060 (Get FASTA)   NCBI Sequence Viewer  
  XP_008951600 (Get FASTA)   NCBI Sequence Viewer  
  XP_008951601 (Get FASTA)   NCBI Sequence Viewer  
  XP_008951602 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000020267.1
  ENSPPAP00000020274.1
  ENSPPAP00000020281.1
RefSeq Acc Id: XP_008951602   ⟸   XM_008953354
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008951601   ⟸   XM_008953353
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008951600   ⟸   XM_008953352
- Peptide Label: isoform X2
- UniProtKB: A0A2R9ASE5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003828060   ⟸   XM_003828012
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AYX7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000020267   ⟸   ENSPPAT00000043059
Ensembl Acc Id: ENSPPAP00000020274   ⟸   ENSPPAT00000043066
Ensembl Acc Id: ENSPPAP00000020281   ⟸   ENSPPAT00000043073
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033363 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000043059.1 UniProtKB/TrEMBL
  ENSPPAT00000043066.1 UniProtKB/TrEMBL
  ENSPPAT00000043073.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro Ca-Reg_Muscle_Contr_Cell_Proc UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
KEGG Report pps:100996176 UniProtKB/TrEMBL
NCBI Gene CALML4 ENTREZGENE
PANTHER CALMODULIN LIKE 4 UniProtKB/TrEMBL
  MYOSIN LIGHT CHAIN 1, 3 UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/TrEMBL
PROSITE EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A2R9ASE5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ASG9_PANPA UniProtKB/TrEMBL
  A0A2R9AYX7 ENTREZGENE, UniProtKB/TrEMBL