KCNK10 (potassium two pore domain channel subfamily K member 10) - Rat Genome Database

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Gene: KCNK10 (potassium two pore domain channel subfamily K member 10) Pan paniscus
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Symbol: KCNK10
Name: potassium two pore domain channel subfamily K member 10
RGD ID: 11923977
Description: ENCODES a protein that exhibits potassium channel activity (ortholog); INVOLVED IN memory (ortholog); ASSOCIATED WITH brain ischemia (ortholog); Deafness (ortholog); Leber congenital amaurosis 3 (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium channel subfamily K member 10; potassium channel, subfamily K, member 10
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21589,318,727 - 89,465,402 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11488,535,233 - 88,681,901 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01468,792,290 - 68,938,947 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11488,152,288 - 88,298,811 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1488,157,714 - 88,235,878 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KCNK10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21589,318,727 - 89,465,402 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11488,535,233 - 88,681,901 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01468,792,290 - 68,938,947 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11488,152,288 - 88,298,811 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1488,157,714 - 88,235,878 (-)Ensemblpanpan1.1panPan2
KCNK10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381488,180,108 - 88,326,912 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1488,180,103 - 88,326,907 (-)EnsemblGRCh38hg38GRCh38
GRCh371488,646,452 - 88,793,256 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361487,720,993 - 87,863,004 (-)NCBINCBI36Build 36hg18NCBI36
Build 341487,720,999 - 87,863,004NCBI
Celera1468,692,135 - 68,838,993 (-)NCBICelera
Cytogenetic Map14q31.3NCBI
HuRef1468,816,576 - 68,963,621 (-)NCBIHuRef
CHM1_11488,584,550 - 88,731,289 (-)NCBICHM1_1
T2T-CHM13v2.01482,400,736 - 82,547,879 (-)NCBIT2T-CHM13v2.0
Kcnk10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391298,395,691 - 98,544,472 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1298,395,696 - 98,544,569 (-)EnsemblGRCm39 Ensembl
GRCm381298,429,432 - 98,578,213 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1298,429,437 - 98,578,310 (-)EnsemblGRCm38mm10GRCm38
MGSCv371299,672,204 - 99,816,150 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361298,835,044 - 98,978,990 (-)NCBIMGSCv36mm8
Celera1299,659,474 - 99,802,888 (-)NCBICelera
Cytogenetic Map12ENCBI
cM Map1249.86NCBI
Kcnk10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86123,419,778 - 123,555,820 (-)NCBIGRCr8
mRatBN7.26117,690,052 - 117,826,120 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6117,694,222 - 117,825,695 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6117,844,163 - 117,973,353 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06118,140,969 - 118,270,161 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06117,475,841 - 117,605,022 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06122,417,079 - 122,549,532 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6122,419,046 - 122,545,899 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06131,631,562 - 131,760,720 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46122,600,156 - 122,729,583 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16122,603,902 - 122,733,330 (-)NCBI
Celera6115,256,086 - 115,384,773 (-)NCBICelera
Cytogenetic Map6q32NCBI
Kcnk10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543810,873,131 - 10,999,441 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543810,867,695 - 10,996,005 (-)NCBIChiLan1.0ChiLan1.0
KCNK10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1859,484,385 - 59,612,891 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl859,484,328 - 59,612,750 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha859,058,106 - 59,190,884 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0859,748,550 - 59,882,007 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl859,753,288 - 59,882,355 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1859,426,150 - 59,559,090 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0859,472,627 - 59,606,367 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0859,806,721 - 59,940,310 (-)NCBIUU_Cfam_GSD_1.0
Kcnk10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864016,240,409 - 16,371,438 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648815,698,143 - 15,827,661 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648815,698,137 - 15,773,582 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNK10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7110,121,263 - 110,271,481 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17110,117,087 - 110,271,877 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27116,613,778 - 116,770,316 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNK10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12465,835,010 - 65,989,030 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2465,835,650 - 65,987,964 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605353,194,967 - 53,339,806 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnk10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473413,990,495 - 14,156,674 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473414,062,218 - 14,161,869 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000015689   ⟹   ENSPPAP00000003410
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1488,157,714 - 88,235,878 (-)Ensembl
RefSeq Acc Id: XM_003832742   ⟹   XP_003832790
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21589,318,727 - 89,465,402 (-)NCBI
NHGRI_mPanPan11488,535,233 - 88,681,901 (-)NCBI
Mhudiblu_PPA_v01468,792,290 - 68,938,947 (-)NCBI
PanPan1.11488,152,288 - 88,298,811 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034937963   ⟹   XP_034793854
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21589,318,727 - 89,461,581 (-)NCBI
NHGRI_mPanPan11488,535,233 - 88,678,087 (-)NCBI
Mhudiblu_PPA_v01468,792,290 - 68,935,132 (-)NCBI
RefSeq Acc Id: XM_034937964   ⟹   XP_034793855
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21589,318,727 - 89,462,559 (-)NCBI
NHGRI_mPanPan11488,535,233 - 88,679,069 (-)NCBI
Mhudiblu_PPA_v01468,792,290 - 68,936,109 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003832790 (Get FASTA)   NCBI Sequence Viewer  
  XP_034793854 (Get FASTA)   NCBI Sequence Viewer  
  XP_034793855 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000003410
  ENSPPAP00000003410.1
RefSeq Acc Id: XP_003832790   ⟸   XM_003832742
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZI00 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034793855   ⟸   XM_034937964
- Peptide Label: isoform X3
- UniProtKB: A0A2R8ZI00 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034793854   ⟸   XM_034937963
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZI00 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000003410   ⟸   ENSPPAT00000015689
Protein Domains
Potassium channel


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000014296 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000015689.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
InterPro 2pore_dom_K_chnl UniProtKB/TrEMBL
  2pore_dom_K_chnl_TREK UniProtKB/TrEMBL
  K_chnl_dom UniProtKB/TrEMBL
NCBI Gene KCNK10 ENTREZGENE
PANTHER POTASSIUM CHANNEL SUBFAMILY K MEMBER 10 UniProtKB/TrEMBL
  PTHR11003 UniProtKB/TrEMBL
Pfam Ion_trans_2 UniProtKB/TrEMBL
PRINTS 2POREKCHANEL UniProtKB/TrEMBL
  TREKCHANNEL UniProtKB/TrEMBL
Superfamily-SCOP Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A2R8ZI00 ENTREZGENE, UniProtKB/TrEMBL