MAPK13 (mitogen-activated protein kinase 13) - Rat Genome Database

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Gene: MAPK13 (mitogen-activated protein kinase 13) Pan paniscus
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Symbol: MAPK13
Name: mitogen-activated protein kinase 13
RGD ID: 11913109
Description: ENCODES a protein that exhibits ATP binding (ortholog); MAP kinase activity (ortholog); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein phosphorylation (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; ASSOCIATED WITH cholestasis (ortholog); proteasome-associated autoinflammatory syndrome 1 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2550,589,442 - 50,619,036 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1646,458,940 - 46,488,555 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0635,689,475 - 35,711,990 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1636,890,205 - 36,904,528 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl636,890,974 - 36,899,388 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MAPK13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2550,589,442 - 50,619,036 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1646,458,940 - 46,488,555 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0635,689,475 - 35,711,990 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1636,890,205 - 36,904,528 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl636,890,974 - 36,899,388 (+)Ensemblpanpan1.1panPan2
MAPK13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38636,130,513 - 36,144,521 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl636,127,809 - 36,144,524 (+)EnsemblGRCh38hg38GRCh38
GRCh37636,098,290 - 36,112,298 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36636,206,240 - 36,215,820 (+)NCBINCBI36Build 36hg18NCBI36
Build 34636,206,239 - 36,215,820NCBI
Celera637,652,800 - 37,662,381 (+)NCBICelera
Cytogenetic Map6p21.31NCBI
HuRef635,818,129 - 35,832,173 (+)NCBIHuRef
CHM1_1636,100,011 - 36,114,054 (+)NCBICHM1_1
T2T-CHM13v2.0635,950,829 - 35,964,842 (+)NCBIT2T-CHM13v2.0
Mapk13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391728,988,260 - 28,997,678 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1728,988,271 - 28,999,207 (+)EnsemblGRCm39 Ensembl
GRCm381728,769,286 - 28,778,704 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1728,769,297 - 28,780,233 (+)EnsemblGRCm38mm10GRCm38
MGSCv371728,906,262 - 28,915,649 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361728,496,946 - 28,506,293 (+)NCBIMGSCv36mm8
Celera1729,324,078 - 29,333,467 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1715.0NCBI
Mapk13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8206,836,979 - 6,847,197 (+)NCBIGRCr8
mRatBN7.2206,835,277 - 6,845,500 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl206,835,320 - 6,844,222 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx207,546,408 - 7,555,599 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0206,908,260 - 6,917,454 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0207,389,575 - 7,399,109 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0206,018,374 - 6,027,467 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl206,018,374 - 6,027,473 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0208,272,098 - 8,281,191 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4207,055,313 - 7,064,405 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1207,055,597 - 7,064,383 (+)NCBI
Celera208,389,500 - 8,398,583 (+)NCBICelera
Cytogenetic Map20p12NCBI
Mapk13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554373,899,950 - 3,909,114 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554373,899,988 - 3,907,781 (+)NCBIChiLan1.0ChiLan1.0
MAPK13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1125,239,783 - 5,248,197 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl125,239,750 - 5,248,196 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha125,259,690 - 5,268,114 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0125,587,473 - 5,595,899 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl125,587,535 - 5,595,894 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1125,242,126 - 5,250,558 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0125,321,188 - 5,329,595 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0125,421,369 - 5,429,783 (+)NCBIUU_Cfam_GSD_1.0
Mapk13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494640,741,448 - 40,748,117 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647623,212,074 - 23,218,775 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647623,212,116 - 23,218,726 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAPK13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl731,880,638 - 31,889,455 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1731,880,643 - 31,889,586 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MAPK13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11735,982,749 - 35,993,956 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1735,983,430 - 35,992,468 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604436,084,986 - 36,097,950 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mapk13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475421,506,369 - 21,513,801 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475421,506,086 - 21,513,803 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000052556   ⟹   ENSPPAP00000029705
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl636,890,974 - 36,899,388 (+)Ensembl
RefSeq Acc Id: XM_003818912   ⟹   XP_003818960
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2550,589,447 - 50,609,735 (+)NCBI
NHGRI_mPanPan1646,458,945 - 46,479,247 (+)NCBI
Mhudiblu_PPA_v0635,689,475 - 35,703,419 (+)NCBI
PanPan1.1636,890,207 - 36,904,528 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034961951   ⟹   XP_034817842
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2550,589,445 - 50,609,735 (+)NCBI
NHGRI_mPanPan1646,458,945 - 46,475,702 (+)NCBI
Mhudiblu_PPA_v0635,689,475 - 35,698,950 (+)NCBI
RefSeq Acc Id: XM_034961952   ⟹   XP_034817843
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2550,589,444 - 50,609,735 (+)NCBI
NHGRI_mPanPan1646,458,944 - 46,479,247 (+)NCBI
Mhudiblu_PPA_v0635,689,475 - 35,700,380 (+)NCBI
RefSeq Acc Id: XM_034961953   ⟹   XP_034817844
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2550,589,444 - 50,615,826 (+)NCBI
NHGRI_mPanPan1646,458,944 - 46,488,555 (+)NCBI
Mhudiblu_PPA_v0635,689,475 - 35,709,508 (+)NCBI
RefSeq Acc Id: XM_034961955   ⟹   XP_034817846
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2550,589,442 - 50,609,735 (+)NCBI
NHGRI_mPanPan1646,458,943 - 46,479,247 (+)NCBI
Mhudiblu_PPA_v0635,689,517 - 35,698,950 (+)NCBI
RefSeq Acc Id: XM_034961956   ⟹   XP_034817847
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2550,596,000 - 50,609,735 (+)NCBI
NHGRI_mPanPan1646,465,510 - 46,475,702 (+)NCBI
Mhudiblu_PPA_v0635,689,692 - 35,698,950 (+)NCBI
RefSeq Acc Id: XM_055113538   ⟹   XP_054969513
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2550,589,443 - 50,609,735 (+)NCBI
NHGRI_mPanPan1646,458,942 - 46,479,247 (+)NCBI
RefSeq Acc Id: XR_004671957
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2550,589,444 - 50,619,036 (+)NCBI
NHGRI_mPanPan1646,458,944 - 46,488,555 (+)NCBI
Mhudiblu_PPA_v0635,689,475 - 35,711,990 (+)NCBI
RefSeq Acc Id: XR_008625605
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2550,589,447 - 50,609,735 (+)NCBI
NHGRI_mPanPan1646,458,945 - 46,479,247 (+)NCBI
RefSeq Acc Id: XR_008625606
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2550,589,443 - 50,609,735 (+)NCBI
NHGRI_mPanPan1646,458,942 - 46,479,247 (+)NCBI
RefSeq Acc Id: XP_003818960   ⟸   XM_003818912
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BJ50 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034817844   ⟸   XM_034961953
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034817843   ⟸   XM_034961952
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034817842   ⟸   XM_034961951
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034817846   ⟸   XM_034961955
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034817847   ⟸   XM_034961956
- Peptide Label: isoform X3
Ensembl Acc Id: ENSPPAP00000029705   ⟸   ENSPPAT00000052556
RefSeq Acc Id: XP_054969513   ⟸   XM_055113538
- Peptide Label: isoform X5
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037868 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000052556.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  MAP_kinase UniProtKB/TrEMBL
  MAPK_p38-like UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
NCBI Gene MAPK13 ENTREZGENE
PANTHER MITOGEN-ACTIVATED PROTEIN KINASE UniProtKB/TrEMBL
  MITOGEN-ACTIVATED PROTEIN KINASE 13 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PRINTS P38MAPKINASE UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A2R9BJ50 ENTREZGENE, UniProtKB/TrEMBL